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The map label for this gene is 222524515

Identifier: 222524515

GI number: 222524515

Start: 1574315

End: 1575991

Strand: Reverse

Name: 222524515

Synonym: Chy400_1239

Alternate gene names: NA

Gene position: 1575991-1574315 (Counterclockwise)

Preceding gene: 222524518

Following gene: 222524512

Centisome position: 29.91

GC content: 58.14

Gene sequence:

>1677_bases
ATGCCCGCAATTGATTTCACGCGCTATTACCGTCCACACGAAGTTGAAGCCGCATTGAAAGCCTGGGCCGAAGAGTATCC
TCACCTTTGTTCTCTGCGTAGCATCGGTACCAGCTACGAGGGACGTTCGATCTGGTTGCTGACGTTGACCAATCAGGCTA
CCGGAGCCGATGACGAAAAACCGGCTTTCTGGCTTGATGCCAACATCCATGCGACCGAAGTGACCGGTTGTATGGGGGCG
CTGCACGTTATTCAGACTGTGCTGACCGGCTACGGTCACGATCCTAACCTGACTGCTTTGCTCGATGAACGTGCATTGTA
TATCGTGCCATGCCTCAACCCCGATGGCATGGAACAGGCGCTCACCTCACCGGTCTATGTGCGCTCAGGTACCCGGCGTT
ACCCATTCACCGACGACCGGGACGGTCTCTACCCGGCTGATATTGATGGCGATGGTTTGATCTTGCAGATGCGCGTGGTC
GATCCCGATGGGGGCTGGAAGGTGAGTGAGCGCGATCCGCGGCTGATGCGGCGGCGTGCTCCCGACGAGCGCGGTGGCAC
GTACTACCGGGTCTATACCGAGGGATTGATTCGCAATTTTGATGGCTACGAGGTCAAGATTGCACCACCGGCCCAGGGGC
TGGATTTTAATCGCAATTTTCCCTACATCTGGGCACCGGAAGGGGTACAGCGTGGTGCTGGCCCGTATCCAACCTCTGAG
CCGGAGATTCGGGCGGCGGTTGAGTTTCTCACCTCCCATCTGAACGTTAGTGGGGCCATCTCATACCACACCTATTCCGG
TGCTATTCTCCGCCCCTATTCCGATAAACCCGACGATCAGATGCCGATTGATGATCTCTGGACGTACAAAGAGCTGGGGA
ATCGCGGCCAGGAGATCACCGGCTACAAACACGTCTCGGTTTATCACGGCTTTCGTTATCACCCGCGTGAAGTCATGCGC
GGCGCTTTCGATGATTGGGCCTACGAACAGCTTGGCATCTTCGCCTTTACCGTCGAGTTGTGGGATATGATCGGCGAGGC
CGGCATTAAGGATCGTGATTTCATCGAATGGTTCCGCGATCATCCCGAAGAGGACGATCTCAAGCTCTTGCGCTGGAATG
ATGAACAGCTTGGCGGCGCCGGTTTTGTCAACTGGCGACCGTTCAATCATCCGCAGCTTGGCCCGGTCGAAATTGGGGGA
TGGATCGAGCGCCGCACGTTTGGCAATCCGCCCGAACAATTTCTGCTACGAACGCTGGAACCCAATACACGCTTTGTCCT
GGCCTTTGCTCAGACCGGCCCACGGCTCGAATTGCGCCACGTGCAGGCCGAAGCGCTAGGCGGTGATCTCTACCGCTTGC
AGGCAGTCGTGGTCAACAGCGGCTATCTGCCGACGTATGGCAGCCGCAAGGCTTTAGAAGTAAAAGCAGTGCAGCCAATT
GAGGTCGAAGTGTTGCTTCCTGAAGGCGGTGAGATCGTGAGCGGTGAACGGCGCCAGGAGATCGGCCAACTGGAAGGGCG
GGCGAACAAGCGCGCGTTGTGGGGAGGGAGTTTCCCAACCGATCATCTGCGGCGCCTGACCTGGACGGTACGTGCACCGG
CGGGCAGCAGCGTCTCGGTGGTTGCCCGTTCCCAGCGCGCCGGTACGGCCCGGGCAACGGTGCAGCTAGACGGTTAG

Upstream 100 bases:

>100_bases
GCTGATTGTTAGAAGTATACCATATGCTTTCTGTTATGTATGACGGGCCATTTGTGGTATTATTATGACGAAGAATGTTT
GACAAAGCAAGGATTGTCTT

Downstream 100 bases:

>100_bases
TATCGCCTTAGAGAATAGGCGGCACTGCACGTGCGCGACTTCTGGGAGGGCGGAACATCTGCTTCCGCCCTCCCAGTATG
TTGCTCCGTGCAGCTATGAG

Product: peptidase M14 carboxypeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MPAIDFTRYYRPHEVEAALKAWAEEYPHLCSLRSIGTSYEGRSIWLLTLTNQATGADDEKPAFWLDANIHATEVTGCMGA
LHVIQTVLTGYGHDPNLTALLDERALYIVPCLNPDGMEQALTSPVYVRSGTRRYPFTDDRDGLYPADIDGDGLILQMRVV
DPDGGWKVSERDPRLMRRRAPDERGGTYYRVYTEGLIRNFDGYEVKIAPPAQGLDFNRNFPYIWAPEGVQRGAGPYPTSE
PEIRAAVEFLTSHLNVSGAISYHTYSGAILRPYSDKPDDQMPIDDLWTYKELGNRGQEITGYKHVSVYHGFRYHPREVMR
GAFDDWAYEQLGIFAFTVELWDMIGEAGIKDRDFIEWFRDHPEEDDLKLLRWNDEQLGGAGFVNWRPFNHPQLGPVEIGG
WIERRTFGNPPEQFLLRTLEPNTRFVLAFAQTGPRLELRHVQAEALGGDLYRLQAVVVNSGYLPTYGSRKALEVKAVQPI
EVEVLLPEGGEIVSGERRQEIGQLEGRANKRALWGGSFPTDHLRRLTWTVRAPAGSSVSVVARSQRAGTARATVQLDG

Sequences:

>Translated_558_residues
MPAIDFTRYYRPHEVEAALKAWAEEYPHLCSLRSIGTSYEGRSIWLLTLTNQATGADDEKPAFWLDANIHATEVTGCMGA
LHVIQTVLTGYGHDPNLTALLDERALYIVPCLNPDGMEQALTSPVYVRSGTRRYPFTDDRDGLYPADIDGDGLILQMRVV
DPDGGWKVSERDPRLMRRRAPDERGGTYYRVYTEGLIRNFDGYEVKIAPPAQGLDFNRNFPYIWAPEGVQRGAGPYPTSE
PEIRAAVEFLTSHLNVSGAISYHTYSGAILRPYSDKPDDQMPIDDLWTYKELGNRGQEITGYKHVSVYHGFRYHPREVMR
GAFDDWAYEQLGIFAFTVELWDMIGEAGIKDRDFIEWFRDHPEEDDLKLLRWNDEQLGGAGFVNWRPFNHPQLGPVEIGG
WIERRTFGNPPEQFLLRTLEPNTRFVLAFAQTGPRLELRHVQAEALGGDLYRLQAVVVNSGYLPTYGSRKALEVKAVQPI
EVEVLLPEGGEIVSGERRQEIGQLEGRANKRALWGGSFPTDHLRRLTWTVRAPAGSSVSVVARSQRAGTARATVQLDG
>Mature_557_residues
PAIDFTRYYRPHEVEAALKAWAEEYPHLCSLRSIGTSYEGRSIWLLTLTNQATGADDEKPAFWLDANIHATEVTGCMGAL
HVIQTVLTGYGHDPNLTALLDERALYIVPCLNPDGMEQALTSPVYVRSGTRRYPFTDDRDGLYPADIDGDGLILQMRVVD
PDGGWKVSERDPRLMRRRAPDERGGTYYRVYTEGLIRNFDGYEVKIAPPAQGLDFNRNFPYIWAPEGVQRGAGPYPTSEP
EIRAAVEFLTSHLNVSGAISYHTYSGAILRPYSDKPDDQMPIDDLWTYKELGNRGQEITGYKHVSVYHGFRYHPREVMRG
AFDDWAYEQLGIFAFTVELWDMIGEAGIKDRDFIEWFRDHPEEDDLKLLRWNDEQLGGAGFVNWRPFNHPQLGPVEIGGW
IERRTFGNPPEQFLLRTLEPNTRFVLAFAQTGPRLELRHVQAEALGGDLYRLQAVVVNSGYLPTYGSRKALEVKAVQPIE
VEVLLPEGGEIVSGERRQEIGQLEGRANKRALWGGSFPTDHLRRLTWTVRAPAGSSVSVVARSQRAGTARATVQLDG

Specific function: Combines the specificities of mammalian Cpase A and B [H]

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M14 family [H]

Homologues:

Organism=Homo sapiens, GI217416390, Length=345, Percent_Identity=24.9275362318841, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI53832021, Length=132, Percent_Identity=34.8484848484849, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38327526, Length=132, Percent_Identity=34.8484848484849, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI6631081, Length=132, Percent_Identity=34.8484848484849, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI22202611, Length=116, Percent_Identity=30.1724137931034, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25143424, Length=277, Percent_Identity=26.3537906137184, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32563693, Length=334, Percent_Identity=27.5449101796407, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI32563699, Length=348, Percent_Identity=24.1379310344828, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193207630, Length=134, Percent_Identity=36.5671641791045, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990283, Length=113, Percent_Identity=31.858407079646, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141274, Length=114, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221372165, Length=113, Percent_Identity=35.3982300884956, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221372158, Length=113, Percent_Identity=35.3982300884956, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221372169, Length=113, Percent_Identity=35.3982300884956, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221372162, Length=113, Percent_Identity=35.3982300884956, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834 [H]

Pfam domain/function: PF00246 Peptidase_M14 [H]

EC number: NA

Molecular weight: Translated: 62971; Mature: 62840

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAIDFTRYYRPHEVEAALKAWAEEYPHLCSLRSIGTSYEGRSIWLLTLTNQATGADDEK
CCCCCCHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCC
PAFWLDANIHATEVTGCMGALHVIQTVLTGYGHDPNLTALLDERALYIVPCLNPDGMEQA
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCCHHHH
LTSPVYVRSGTRRYPFTDDRDGLYPADIDGDGLILQMRVVDPDGGWKVSERDPRLMRRRA
HCCCEEEECCCCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCEEECCCCHHHHHHCC
PDERGGTYYRVYTEGLIRNFDGYEVKIAPPAQGLDFNRNFPYIWAPEGVQRGAGPYPTSE
CCCCCCCEEEEEECHHHCCCCCCEEEECCCCCCCCCCCCCCEEECCCHHHCCCCCCCCCC
PEIRAAVEFLTSHLNVSGAISYHTYSGAILRPYSDKPDDQMPIDDLWTYKELGNRGQEIT
HHHHHHHHHHHHHCCCCEEEEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCC
GYKHVSVYHGFRYHPREVMRGAFDDWAYEQLGIFAFTVELWDMIGEAGIKDRDFIEWFRD
CEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHEEEHHHHHHHHHHCCCCCHHHHHHHHC
HPEEDDLKLLRWNDEQLGGAGFVNWRPFNHPQLGPVEIGGWIERRTFGNPPEQFLLRTLE
CCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCEEECCEEEECCCCCCHHHHHHHHCC
PNTRFVLAFAQTGPRLELRHVQAEALGGDLYRLQAVVVNSGYLPTYGSRKALEVKAVQPI
CCCEEEEEEECCCCCEEEEEEEHHHCCCCEEEEEEEEEECCCCCCCCCCCEEEEEECCCE
EVEVLLPEGGEIVSGERRQEIGQLEGRANKRALWGGSFPTDHLRRLTWTVRAPAGSSVSV
EEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHEEEEEEEECCCCCCEEE
VARSQRAGTARATVQLDG
EEECCCCCCEEEEEEECC
>Mature Secondary Structure 
PAIDFTRYYRPHEVEAALKAWAEEYPHLCSLRSIGTSYEGRSIWLLTLTNQATGADDEK
CCCCCHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCC
PAFWLDANIHATEVTGCMGALHVIQTVLTGYGHDPNLTALLDERALYIVPCLNPDGMEQA
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCCHHHH
LTSPVYVRSGTRRYPFTDDRDGLYPADIDGDGLILQMRVVDPDGGWKVSERDPRLMRRRA
HCCCEEEECCCCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCEEECCCCHHHHHHCC
PDERGGTYYRVYTEGLIRNFDGYEVKIAPPAQGLDFNRNFPYIWAPEGVQRGAGPYPTSE
CCCCCCCEEEEEECHHHCCCCCCEEEECCCCCCCCCCCCCCEEECCCHHHCCCCCCCCCC
PEIRAAVEFLTSHLNVSGAISYHTYSGAILRPYSDKPDDQMPIDDLWTYKELGNRGQEIT
HHHHHHHHHHHHHCCCCEEEEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCC
GYKHVSVYHGFRYHPREVMRGAFDDWAYEQLGIFAFTVELWDMIGEAGIKDRDFIEWFRD
CEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHEEEHHHHHHHHHHCCCCCHHHHHHHHC
HPEEDDLKLLRWNDEQLGGAGFVNWRPFNHPQLGPVEIGGWIERRTFGNPPEQFLLRTLE
CCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCEEECCEEEECCCCCCHHHHHHHHCC
PNTRFVLAFAQTGPRLELRHVQAEALGGDLYRLQAVVVNSGYLPTYGSRKALEVKAVQPI
CCCEEEEEEECCCCCEEEEEEEHHHCCCCEEEEEEEEEECCCCCCCCCCCEEEEEECCCE
EVEVLLPEGGEIVSGERRQEIGQLEGRANKRALWGGSFPTDHLRRLTWTVRAPAGSSVSV
EEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHEEEEEEEECCCCCCEEE
VARSQRAGTARATVQLDG
EEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA