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The map label for this gene is glmS [H]

Identifier: 222524492

GI number: 222524492

Start: 1551507

End: 1552541

Strand: Direct

Name: glmS [H]

Synonym: Chy400_1216

Alternate gene names: 222524492

Gene position: 1551507-1552541 (Clockwise)

Preceding gene: 222524491

Following gene: 222524493

Centisome position: 29.45

GC content: 52.66

Gene sequence:

>1035_bases
ATGACCATTCAACACGAAATTTACGCACAACCCACAGTTATTAGTGAACTACTTGAACATGGGTTGGTACAGGCATACCA
ATTGGCCGCTAAAATTCGCAAGCATGATATCCGTTATGTGTATGCAGCCGGTCGGGGAACTTCTGAACATGCCAGTATTT
ACGGTCAGTATTTGTTCGGGACGCTCAATCGGTTACCGGTAGCGCTAGCTGCGCCATCACTTTTCACTATCTATCAGCAG
CCACCAAACCTGCGCCACGCATTAGTTATCGGCGTTTCGCAATCGGGGCAATCTCCAGACATTCTGGCAGTGATTGATGA
AGCACAACGGCAAGGGGCTCTCACGCTGGCTATAACCAACGATCCAGCTTCGCCATTGGCTCAGCACGCTGCCCTCCACT
TCGACATCGCTGCCGGCCCAGAGTTAGCAGTAGCCGCGACGAAAACCTACACGGCTCAACTGACCGCTTTCGCATTGCTG
GCAATAGCGCTGGCCGATGATCAGGCAAGATTAACTGAATTGCGCCGACTTCCTGTAGCACTTACTGAAGCCTTGCAACT
CGAAGAAGTTGTAGCAACTGCTGCCAGCCATTTTCGCACGATGTCATACTGTGTAGTACTTGGTCGTGGATTTCAACTGG
CAACTGCTCTGGAATGGTCGCTGAAACTGAAAGAGATGGCCTATGTCGTAGCCGAACGCTACTCTACCGCCGAGTTTCAA
CACGGCCCAATTGCTCTGATCGAGCCAGGGTTTCCAGTGCTAGCTGTGGCTACCCGCGATGCTGGCAGTATGTACATCGC
CAATCTGCTCGACCGCTTACGAGCCGCTGGCGCTGAATTGCTCGTACTCAGTGATGATCGCACACTCTTTGCGCACGGTG
TTACCGGCTTGCTCATACCCGCAGGTATTCCCGACTGGTTAACCCCCATCGTTACCATCGTTCCGGCACAACTATTCTGT
TACCATCTAGCCCTGGCACGAGGCGTCGATCCGTTGCATCCCCGCGGGTTACGAAAAATAACACGCACCCACTGA

Upstream 100 bases:

>100_bases
TGCAACCGGTAGCCTTGAAAGCACTTGCTGCTGGCCTATGGGGTGAAATTCCATTCCAGGGTAAGCTACCATTACGAGTA
TTGTCTGAGGAATTTAATGT

Downstream 100 bases:

>100_bases
TATGATGAGCCTGGATTGGCACCTGCCTGATTGCAACTTATTCATCGTCAGCTCATGATGAAACTGCTAAAAGCACGAAA
GCGTCTATCATGCGCAGCAG

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTIQHEIYAQPTVISELLEHGLVQAYQLAAKIRKHDIRYVYAAGRGTSEHASIYGQYLFGTLNRLPVALAAPSLFTIYQQ
PPNLRHALVIGVSQSGQSPDILAVIDEAQRQGALTLAITNDPASPLAQHAALHFDIAAGPELAVAATKTYTAQLTAFALL
AIALADDQARLTELRRLPVALTEALQLEEVVATAASHFRTMSYCVVLGRGFQLATALEWSLKLKEMAYVVAERYSTAEFQ
HGPIALIEPGFPVLAVATRDAGSMYIANLLDRLRAAGAELLVLSDDRTLFAHGVTGLLIPAGIPDWLTPIVTIVPAQLFC
YHLALARGVDPLHPRGLRKITRTH

Sequences:

>Translated_344_residues
MTIQHEIYAQPTVISELLEHGLVQAYQLAAKIRKHDIRYVYAAGRGTSEHASIYGQYLFGTLNRLPVALAAPSLFTIYQQ
PPNLRHALVIGVSQSGQSPDILAVIDEAQRQGALTLAITNDPASPLAQHAALHFDIAAGPELAVAATKTYTAQLTAFALL
AIALADDQARLTELRRLPVALTEALQLEEVVATAASHFRTMSYCVVLGRGFQLATALEWSLKLKEMAYVVAERYSTAEFQ
HGPIALIEPGFPVLAVATRDAGSMYIANLLDRLRAAGAELLVLSDDRTLFAHGVTGLLIPAGIPDWLTPIVTIVPAQLFC
YHLALARGVDPLHPRGLRKITRTH
>Mature_343_residues
TIQHEIYAQPTVISELLEHGLVQAYQLAAKIRKHDIRYVYAAGRGTSEHASIYGQYLFGTLNRLPVALAAPSLFTIYQQP
PNLRHALVIGVSQSGQSPDILAVIDEAQRQGALTLAITNDPASPLAQHAALHFDIAAGPELAVAATKTYTAQLTAFALLA
IALADDQARLTELRRLPVALTEALQLEEVVATAASHFRTMSYCVVLGRGFQLATALEWSLKLKEMAYVVAERYSTAEFQH
GPIALIEPGFPVLAVATRDAGSMYIANLLDRLRAAGAELLVLSDDRTLFAHGVTGLLIPAGIPDWLTPIVTIVPAQLFCY
HLALARGVDPLHPRGLRKITRTH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=354, Percent_Identity=29.9435028248588, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4826742, Length=357, Percent_Identity=32.4929971988796, Blast_Score=165, Evalue=6e-41,
Organism=Escherichia coli, GI1790167, Length=353, Percent_Identity=32.0113314447592, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI87082251, Length=327, Percent_Identity=23.2415902140673, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532899, Length=356, Percent_Identity=29.7752808988764, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17532897, Length=356, Percent_Identity=29.7752808988764, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17539970, Length=355, Percent_Identity=27.3239436619718, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6322745, Length=311, Percent_Identity=30.5466237942122, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6323731, Length=360, Percent_Identity=26.1111111111111, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21357745, Length=304, Percent_Identity=31.25, Blast_Score=157, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 37288; Mature: 37156

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQHEIYAQPTVISELLEHGLVQAYQLAAKIRKHDIRYVYAAGRGTSEHASIYGQYLFG
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHH
TLNRLPVALAAPSLFTIYQQPPNLRHALVIGVSQSGQSPDILAVIDEAQRQGALTLAITN
HHHHCCHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEEHHHHCCCEEEEEEC
DPASPLAQHAALHFDIAAGPELAVAATKTYTAQLTAFALLAIALADDQARLTELRRLPVA
CCCHHHHHHHEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHH
LTEALQLEEVVATAASHFRTMSYCVVLGRGFQLATALEWSLKLKEMAYVVAERYSTAEFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
HGPIALIEPGFPVLAVATRDAGSMYIANLLDRLRAAGAELLVLSDDRTLFAHGVTGLLIP
CCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCEEEEC
AGIPDWLTPIVTIVPAQLFCYHLALARGVDPLHPRGLRKITRTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TIQHEIYAQPTVISELLEHGLVQAYQLAAKIRKHDIRYVYAAGRGTSEHASIYGQYLFG
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHH
TLNRLPVALAAPSLFTIYQQPPNLRHALVIGVSQSGQSPDILAVIDEAQRQGALTLAITN
HHHHCCHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEEHHHHCCCEEEEEEC
DPASPLAQHAALHFDIAAGPELAVAATKTYTAQLTAFALLAIALADDQARLTELRRLPVA
CCCHHHHHHHEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHH
LTEALQLEEVVATAASHFRTMSYCVVLGRGFQLATALEWSLKLKEMAYVVAERYSTAEFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
HGPIALIEPGFPVLAVATRDAGSMYIANLLDRLRAAGAELLVLSDDRTLFAHGVTGLLIP
CCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCEEEEC
AGIPDWLTPIVTIVPAQLFCYHLALARGVDPLHPRGLRKITRTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA