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The map label for this gene is yuxL [H]

Identifier: 222524445

GI number: 222524445

Start: 1482975

End: 1485011

Strand: Reverse

Name: yuxL [H]

Synonym: Chy400_1169

Alternate gene names: 222524445

Gene position: 1485011-1482975 (Counterclockwise)

Preceding gene: 222524447

Following gene: 222524441

Centisome position: 28.18

GC content: 57.58

Gene sequence:

>2037_bases
ATGACAAACCAACCCCCTGGTCGCTTTACCATTGACGATCTCTACGAATTAGGCTGGCTGGAAGACCCCCGGCTTAGTCC
CGACGGACGGTACGTGGCGGTCGTGTGGGTGACGGTGGATCGCGTCGGTAACGGCTATCGGCGGCACATTGTGCTAGTTG
CTACCGATGGTGGTCAAATACGTCGCTTCACCCGCGGTAAACAAGATCGCCAGCCACGCTGGAGTCCTGATGGGCGCTGG
ATTGCATTTGTCTCGAACCGCGACGATGAACGAGGGCAGATTTATATCATCCCGGTCGATGGTGGTGAAGCACGCCAGAT
AACCTCGCATCCCAACGGAGCGAGCGATCCGGCATGGAGTCCTGATGGACGATATATCGCGTTTTTGGCGCCGGTAAATG
CTGAAGAGCAGGCTCGTGAAGATGCCGGTGAAACACCACCACCACCAGCCGATGCCTGGGAAGCACGTCGCAGTCGCGAG
CAGCGCCAGCATGAAGAAGAAATGCGCGTTGATCCGCGTGTGATTACCAAACTTCCCTATCGCAGTGGTACCAGTTATTT
TGATGATCGTCGCCGCCATATTTACCTCGTTGAAGTTACTGATGATGATCAGCCATCAACCCCACGCCGGTTGACCTCCG
GTGACATCCACTACAGCGCACCGGTCTGGATGCCGGCAGGCGATGCGCTCTTGAGCACGGCAACCCGCGATCCCGAAGCC
GACTCGCTCTTTGCCTATTACGATGTGATGTGCGTTCCACTCGATGGCTCGTCGCCACACCCGCTAACCAGTAGTGGCTT
TTCCTATTTTGATCCGCGCCCATCCCCTGATGGCACTCAGATCGCGTTTCTGCGCTTGAACGAGTCGCGCCTCCTCGGTG
AAGGAAAACGGGTGGCGATTATTCCGGCTACCGGCGGCGAACCGCACGATCTTACGGCGCATACCGATCTGAATGTGGAA
CAATTTCACTGGCAACCCGATGGCCAGGGGGTGTTGTTCAGTGCAGGCTGGCGCGGCGATGCCCATGTCTATCAGATAGG
ACTACCGGGAACACCAACTTATCGTAATGGCGCAACGCTGGTCGGCGGGCCGCGGATCGTTAGCGAATTCGATGTCGGGC
GCGATGGCACCATTGCCTTTGTAGCTGGAAGTGCCGACAATCCGTGCGATCTCTTCGTGCGTGGCGCTGACGGTCAGGAA
CGGCGTCTGACTGCTATCAACGAGCGCTTACTGAGCCAGCGCATTATTGTGCCAATTGAAGAAATAACCTATCTCGCACC
CGATGGCAGTGAAGTGCAGGGTTGGACGCTCCATCCACCCGATTTCGATCCGGCGCAGCGCTATCCGCTGGCCGTCTACA
TTCACGGCGGCCCACATATTATGTGGGGGCCGGGTTTCCGTTCGATGTGGCACGAGTGGCAGGTCGCTGCTGCCCGTGGC
TATGTCGTCTTCTTCTGCAATCCCCGCGGCAGTGAGGGCTACGGCGAGCTGTGGCGTGACGCGATCCGGGGGAACTGGGG
TGAAGCGGATGCCCCTGATATTCTGGCCGGGATTGATGCCCTGGTTGCTCGTGGCTATATTGATCCCGAACGGATCGGAG
TGACCGGCGGGTCGTATGGTGGCTATATGACGGCCTGGCTGATCGGGCACGATGATCGGTTCGCCTGTGCTGTGGCTGCC
CGTGGGGTCTACAATCTTCTCACCCAACACAGCACCAGTGACGCCCATGAACTGATCGAAATTGAATTTGGCGGTTTTCC
CTGGGAGTTGTACGAGGAGCTGTGGGATCATTCGCCATTGGCCCACGCGCACAAGATTAAAACGCCACTCTTGCTCTTGC
ATAGCGAGCTTGATTACCGGGTACCGATCAGCGAAGCCGAACAACTCTTCGCCATTCTCCGCCGCCAAAAGAAAGTGGTT
GAACTGGTGCGTTACCCGCGCGAGGGCCATGAACTGACTCGTAGCGGCGAACCACGCCATCGCGCCGATCATATGCGACG
AACCCTGGAGTGGTTTGATCGGTATTTGAAAGAGTGA

Upstream 100 bases:

>100_bases
ATTCTATACTTTCTAGCAAAAATCTCAAACGCCGATCAATGAGAAGTGTGTTACAATAGCAAGGTCTGTGTACCCGCTTA
ATAATTCATGGGGCCGAGTT

Downstream 100 bases:

>100_bases
TCTCTCTCCCAAACCCCCTTCAAGGGCGGACAAAACATACGAACGCAGTCAGGAGATAGGGCTGAATATCAAATCTGGTG
TCATGGCGTTCAAAACCTGT

Product: peptidase S9 prolyl oligopeptidase active site domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MTNQPPGRFTIDDLYELGWLEDPRLSPDGRYVAVVWVTVDRVGNGYRRHIVLVATDGGQIRRFTRGKQDRQPRWSPDGRW
IAFVSNRDDERGQIYIIPVDGGEARQITSHPNGASDPAWSPDGRYIAFLAPVNAEEQAREDAGETPPPPADAWEARRSRE
QRQHEEEMRVDPRVITKLPYRSGTSYFDDRRRHIYLVEVTDDDQPSTPRRLTSGDIHYSAPVWMPAGDALLSTATRDPEA
DSLFAYYDVMCVPLDGSSPHPLTSSGFSYFDPRPSPDGTQIAFLRLNESRLLGEGKRVAIIPATGGEPHDLTAHTDLNVE
QFHWQPDGQGVLFSAGWRGDAHVYQIGLPGTPTYRNGATLVGGPRIVSEFDVGRDGTIAFVAGSADNPCDLFVRGADGQE
RRLTAINERLLSQRIIVPIEEITYLAPDGSEVQGWTLHPPDFDPAQRYPLAVYIHGGPHIMWGPGFRSMWHEWQVAAARG
YVVFFCNPRGSEGYGELWRDAIRGNWGEADAPDILAGIDALVARGYIDPERIGVTGGSYGGYMTAWLIGHDDRFACAVAA
RGVYNLLTQHSTSDAHELIEIEFGGFPWELYEELWDHSPLAHAHKIKTPLLLLHSELDYRVPISEAEQLFAILRRQKKVV
ELVRYPREGHELTRSGEPRHRADHMRRTLEWFDRYLKE

Sequences:

>Translated_678_residues
MTNQPPGRFTIDDLYELGWLEDPRLSPDGRYVAVVWVTVDRVGNGYRRHIVLVATDGGQIRRFTRGKQDRQPRWSPDGRW
IAFVSNRDDERGQIYIIPVDGGEARQITSHPNGASDPAWSPDGRYIAFLAPVNAEEQAREDAGETPPPPADAWEARRSRE
QRQHEEEMRVDPRVITKLPYRSGTSYFDDRRRHIYLVEVTDDDQPSTPRRLTSGDIHYSAPVWMPAGDALLSTATRDPEA
DSLFAYYDVMCVPLDGSSPHPLTSSGFSYFDPRPSPDGTQIAFLRLNESRLLGEGKRVAIIPATGGEPHDLTAHTDLNVE
QFHWQPDGQGVLFSAGWRGDAHVYQIGLPGTPTYRNGATLVGGPRIVSEFDVGRDGTIAFVAGSADNPCDLFVRGADGQE
RRLTAINERLLSQRIIVPIEEITYLAPDGSEVQGWTLHPPDFDPAQRYPLAVYIHGGPHIMWGPGFRSMWHEWQVAAARG
YVVFFCNPRGSEGYGELWRDAIRGNWGEADAPDILAGIDALVARGYIDPERIGVTGGSYGGYMTAWLIGHDDRFACAVAA
RGVYNLLTQHSTSDAHELIEIEFGGFPWELYEELWDHSPLAHAHKIKTPLLLLHSELDYRVPISEAEQLFAILRRQKKVV
ELVRYPREGHELTRSGEPRHRADHMRRTLEWFDRYLKE
>Mature_677_residues
TNQPPGRFTIDDLYELGWLEDPRLSPDGRYVAVVWVTVDRVGNGYRRHIVLVATDGGQIRRFTRGKQDRQPRWSPDGRWI
AFVSNRDDERGQIYIIPVDGGEARQITSHPNGASDPAWSPDGRYIAFLAPVNAEEQAREDAGETPPPPADAWEARRSREQ
RQHEEEMRVDPRVITKLPYRSGTSYFDDRRRHIYLVEVTDDDQPSTPRRLTSGDIHYSAPVWMPAGDALLSTATRDPEAD
SLFAYYDVMCVPLDGSSPHPLTSSGFSYFDPRPSPDGTQIAFLRLNESRLLGEGKRVAIIPATGGEPHDLTAHTDLNVEQ
FHWQPDGQGVLFSAGWRGDAHVYQIGLPGTPTYRNGATLVGGPRIVSEFDVGRDGTIAFVAGSADNPCDLFVRGADGQER
RLTAINERLLSQRIIVPIEEITYLAPDGSEVQGWTLHPPDFDPAQRYPLAVYIHGGPHIMWGPGFRSMWHEWQVAAARGY
VVFFCNPRGSEGYGELWRDAIRGNWGEADAPDILAGIDALVARGYIDPERIGVTGGSYGGYMTAWLIGHDDRFACAVAAR
GVYNLLTQHSTSDAHELIEIEFGGFPWELYEELWDHSPLAHAHKIKTPLLLLHSELDYRVPISEAEQLFAILRRQKKVVE
LVRYPREGHELTRSGEPRHRADHMRRTLEWFDRYLKE

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=273, Percent_Identity=26.007326007326, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI18450280, Length=261, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI37577089, Length=261, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI16933540, Length=288, Percent_Identity=25.6944444444444, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI18765694, Length=268, Percent_Identity=23.5074626865672, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17552908, Length=281, Percent_Identity=30.6049822064057, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI25144540, Length=235, Percent_Identity=30.2127659574468, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25144537, Length=235, Percent_Identity=30.2127659574468, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25149159, Length=270, Percent_Identity=29.2592592592593, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17564632, Length=266, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564634, Length=266, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508019, Length=221, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17508017, Length=221, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25144543, Length=126, Percent_Identity=37.3015873015873, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551969, Length=232, Percent_Identity=26.2931034482759, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45550825, Length=232, Percent_Identity=26.2931034482759, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45553511, Length=232, Percent_Identity=26.2931034482759, Blast_Score=77, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 76367; Mature: 76236

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQPPGRFTIDDLYELGWLEDPRLSPDGRYVAVVWVTVDRVGNGYRRHIVLVATDGGQI
CCCCCCCCEEHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEEECCCCHH
RRFTRGKQDRQPRWSPDGRWIAFVSNRDDERGQIYIIPVDGGEARQITSHPNGASDPAWS
HHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCC
PDGRYIAFLAPVNAEEQAREDAGETPPPPADAWEARRSREQRQHEEEMRVDPRVITKLPY
CCCCEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCC
RSGTSYFDDRRRHIYLVEVTDDDQPSTPRRLTSGDIHYSAPVWMPAGDALLSTATRDPEA
CCCCCHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCEECCCCHHHHHHCCCCCCC
DSLFAYYDVMCVPLDGSSPHPLTSSGFSYFDPRPSPDGTQIAFLRLNESRLLGEGKRVAI
CCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHCCCCCEEEE
IPATGGEPHDLTAHTDLNVEQFHWQPDGQGVLFSAGWRGDAHVYQIGLPGTPTYRNGATL
EECCCCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCEE
VGGPRIVSEFDVGRDGTIAFVAGSADNPCDLFVRGADGQERRLTAINERLLSQRIIVPIE
ECCCEEEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEHH
EITYLAPDGSEVQGWTLHPPDFDPAQRYPLAVYIHGGPHIMWGPGFRSMWHEWQVAAARG
HEEEECCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHEEEEECC
YVVFFCNPRGSEGYGELWRDAIRGNWGEADAPDILAGIDALVARGYIDPERIGVTGGSYG
EEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHEEECCCCCC
GYMTAWLIGHDDRFACAVAARGVYNLLTQHSTSDAHELIEIEFGGFPWELYEELWDHSPL
CEEEEEEEECCCCEEEHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCC
AHAHKIKTPLLLLHSELDYRVPISEAEQLFAILRRQKKVVELVRYPREGHELTRSGEPRH
CHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHH
RADHMRRTLEWFDRYLKE
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNQPPGRFTIDDLYELGWLEDPRLSPDGRYVAVVWVTVDRVGNGYRRHIVLVATDGGQI
CCCCCCCEEHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEEECCCCHH
RRFTRGKQDRQPRWSPDGRWIAFVSNRDDERGQIYIIPVDGGEARQITSHPNGASDPAWS
HHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCC
PDGRYIAFLAPVNAEEQAREDAGETPPPPADAWEARRSREQRQHEEEMRVDPRVITKLPY
CCCCEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCC
RSGTSYFDDRRRHIYLVEVTDDDQPSTPRRLTSGDIHYSAPVWMPAGDALLSTATRDPEA
CCCCCHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCEECCCCHHHHHHCCCCCCC
DSLFAYYDVMCVPLDGSSPHPLTSSGFSYFDPRPSPDGTQIAFLRLNESRLLGEGKRVAI
CCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHCCCCCEEEE
IPATGGEPHDLTAHTDLNVEQFHWQPDGQGVLFSAGWRGDAHVYQIGLPGTPTYRNGATL
EECCCCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCEE
VGGPRIVSEFDVGRDGTIAFVAGSADNPCDLFVRGADGQERRLTAINERLLSQRIIVPIE
ECCCEEEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEHH
EITYLAPDGSEVQGWTLHPPDFDPAQRYPLAVYIHGGPHIMWGPGFRSMWHEWQVAAARG
HEEEECCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHEEEEECC
YVVFFCNPRGSEGYGELWRDAIRGNWGEADAPDILAGIDALVARGYIDPERIGVTGGSYG
EEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHEEECCCCCC
GYMTAWLIGHDDRFACAVAARGVYNLLTQHSTSDAHELIEIEFGGFPWELYEELWDHSPL
CEEEEEEEECCCCEEEHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCC
AHAHKIKTPLLLLHSELDYRVPISEAEQLFAILRRQKKVVELVRYPREGHELTRSGEPRH
CHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHH
RADHMRRTLEWFDRYLKE
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]