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The map label for this gene is lacD [H]

Identifier: 222524447

GI number: 222524447

Start: 1486234

End: 1487274

Strand: Reverse

Name: lacD [H]

Synonym: Chy400_1171

Alternate gene names: 222524447

Gene position: 1487274-1486234 (Counterclockwise)

Preceding gene: 222524451

Following gene: 222524445

Centisome position: 28.23

GC content: 56.2

Gene sequence:

>1041_bases
ATGGCTAAAGTACAGATGACGCGAGGCAAATTTAACGGAATCCAGGCTTGCGCAGACGCTAATGGCATTATTGCTGCCGC
AGCGATGGATCAGCGGGGTTCGTTGAAGAAGGCGATTGCGAAAGCTCGCGGTGCTGAGGCAACGAATGAAGATTTGACGG
CATTTAAAACGGCTGTGACCCGCATTTTGACCCGGTATGCCAGCGCCATTTTGATGGATCCGGAGTATGGTTTGCCCGCT
ATTGCCCAGCGTGCCCCTGGTACCGGTGTGCTGCTGGCCTATGAGAAGACCGGTTATGATGCCTCGGTGCGTGGCCGGCT
GCCCGACCTGCTCGATGTCTGGAGTGTGCGGCGCTTGAAAGAGGCTGGCGCCGACGCGATCAAGATTCTGCTCTACTACA
ATCCCTTCGATGATGCCGCTATCAATGAGGTAAAGCATGCCTTCATCGAGCGGATTGGTGCAGAGTGTGCGGCAAATGAT
ATTCCTTTCTTCCTTGAACCAATTGCGTATGATGATGCCGTGGGCGACGAGAAGAGCTTCGAGTTTGCCCTGGTGAAGCC
GAAGTATGTGACCGCCTATATGGCCGAGTTCTCAAAGCCGCGCTATGGGGTTGATGTGTTGAAGGTCGAAGTGCCGGTGA
ATGTCAAGTTTGTCGAAGGGATGCGCGTGTTCAGCGGCCAGAAGGCGTATAGCCGCGAAGAGGCTAAAGAGTTCTTCCGC
CAGGCTGCTGATGCAGCGCGCAAGCCGTTTATCTATCTCAGTGCCGGCGTTTCCGACGAGGTCTTCCGCGAGACGCTTGA
GCTGGCTGCTGAGGCCGGGACACCTTTCGCGGGTGTGTTGTGTGGTCGGGCCACCTGGCAGGATGGCATCCCGGTCTATG
CCCAGCAAGGACTGGGAGCGCTCGAAGCATGGCTGGAGGATCGCGGGGTTGCCAATATTACGGCCCTGAATGAGACACTG
GCTCAGGGTGCCAAACCCTGGTGGACGATCTACGGCGGTTTGGAGAACATTGAAGTGATCGATCTGCCCGTTCAGCAATA
A

Upstream 100 bases:

>100_bases
TAACTCATCATGGTATCGCTGTCGTTCCGCACCGGGAGTTATACACACCTGACATCTGCTACCGGTTGCTGCCCGATTGT
TTGAGCTAAGGAGTTGACTC

Downstream 100 bases:

>100_bases
ACCCGCCCTGGCGTGGATCAATCCACTGCCGAAAAGCTCATACGTTAGCGTGAGTGCGGAAGCTATGCTCCCGCACTCAT
TATTTACTGCTGGACAAGAT

Product: tagatose 1,6-diphosphate aldolase

Products: NA

Alternate protein names: D-tagatose-1,6-bisphosphate aldolase; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MAKVQMTRGKFNGIQACADANGIIAAAAMDQRGSLKKAIAKARGAEATNEDLTAFKTAVTRILTRYASAILMDPEYGLPA
IAQRAPGTGVLLAYEKTGYDASVRGRLPDLLDVWSVRRLKEAGADAIKILLYYNPFDDAAINEVKHAFIERIGAECAAND
IPFFLEPIAYDDAVGDEKSFEFALVKPKYVTAYMAEFSKPRYGVDVLKVEVPVNVKFVEGMRVFSGQKAYSREEAKEFFR
QAADAARKPFIYLSAGVSDEVFRETLELAAEAGTPFAGVLCGRATWQDGIPVYAQQGLGALEAWLEDRGVANITALNETL
AQGAKPWWTIYGGLENIEVIDLPVQQ

Sequences:

>Translated_346_residues
MAKVQMTRGKFNGIQACADANGIIAAAAMDQRGSLKKAIAKARGAEATNEDLTAFKTAVTRILTRYASAILMDPEYGLPA
IAQRAPGTGVLLAYEKTGYDASVRGRLPDLLDVWSVRRLKEAGADAIKILLYYNPFDDAAINEVKHAFIERIGAECAAND
IPFFLEPIAYDDAVGDEKSFEFALVKPKYVTAYMAEFSKPRYGVDVLKVEVPVNVKFVEGMRVFSGQKAYSREEAKEFFR
QAADAARKPFIYLSAGVSDEVFRETLELAAEAGTPFAGVLCGRATWQDGIPVYAQQGLGALEAWLEDRGVANITALNETL
AQGAKPWWTIYGGLENIEVIDLPVQQ
>Mature_345_residues
AKVQMTRGKFNGIQACADANGIIAAAAMDQRGSLKKAIAKARGAEATNEDLTAFKTAVTRILTRYASAILMDPEYGLPAI
AQRAPGTGVLLAYEKTGYDASVRGRLPDLLDVWSVRRLKEAGADAIKILLYYNPFDDAAINEVKHAFIERIGAECAANDI
PFFLEPIAYDDAVGDEKSFEFALVKPKYVTAYMAEFSKPRYGVDVLKVEVPVNVKFVEGMRVFSGQKAYSREEAKEFFRQ
AADAARKPFIYLSAGVSDEVFRETLELAAEAGTPFAGVLCGRATWQDGIPVYAQQGLGALEAWLEDRGVANITALNETLA
QGAKPWWTIYGGLENIEVIDLPVQQ

Specific function: Unknown

COG id: COG3684

COG function: function code G; Tagatose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase lacD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 37781; Mature: 37650

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVQMTRGKFNGIQACADANGIIAAAAMDQRGSLKKAIAKARGAEATNEDLTAFKTAVT
CCCEEECCCCCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
RILTRYASAILMDPEYGLPAIAQRAPGTGVLLAYEKTGYDASVRGRLPDLLDVWSVRRLK
HHHHHHHHHEEECCCCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
EAGADAIKILLYYNPFDDAAINEVKHAFIERIGAECAANDIPFFLEPIAYDDAVGDEKSF
HCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCC
EFALVKPKYVTAYMAEFSKPRYGVDVLKVEVPVNVKFVEGMRVFSGQKAYSREEAKEFFR
EEEEECCHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCHHHHCCCHHHHHHHHHHHHH
QAADAARKPFIYLSAGVSDEVFRETLELAAEAGTPFAGVLCGRATWQDGIPVYAQQGLGA
HHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHCCCHH
LEAWLEDRGVANITALNETLAQGAKPWWTIYGGLENIEVIDLPVQQ
HHHHHHCCCCEEHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCC
>Mature Secondary Structure 
AKVQMTRGKFNGIQACADANGIIAAAAMDQRGSLKKAIAKARGAEATNEDLTAFKTAVT
CCEEECCCCCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
RILTRYASAILMDPEYGLPAIAQRAPGTGVLLAYEKTGYDASVRGRLPDLLDVWSVRRLK
HHHHHHHHHEEECCCCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
EAGADAIKILLYYNPFDDAAINEVKHAFIERIGAECAANDIPFFLEPIAYDDAVGDEKSF
HCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCC
EFALVKPKYVTAYMAEFSKPRYGVDVLKVEVPVNVKFVEGMRVFSGQKAYSREEAKEFFR
EEEEECCHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCHHHHCCCHHHHHHHHHHHHH
QAADAARKPFIYLSAGVSDEVFRETLELAAEAGTPFAGVLCGRATWQDGIPVYAQQGLGA
HHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHCCCHH
LEAWLEDRGVANITALNETLAQGAKPWWTIYGGLENIEVIDLPVQQ
HHHHHHCCCCEEHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]