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The map label for this gene is pld [H]

Identifier: 222524138

GI number: 222524138

Start: 1076884

End: 1078041

Strand: Direct

Name: pld [H]

Synonym: Chy400_0854

Alternate gene names: 222524138

Gene position: 1076884-1078041 (Clockwise)

Preceding gene: 222524137

Following gene: 222524145

Centisome position: 20.44

GC content: 56.04

Gene sequence:

>1158_bases
ATGGCGCGCAAGCCCTCTTCGTCACGACCGTATCGCCCCAACCGCACGCAGATCATATTGCTGTTTCTCATCCTGGCCCT
CGGTTATCTGATTAACGCCGGGATTATTGATCTACGCCGCTTCGGTCTCGATCCGGCGCTGTTCGGGATTGAAACCCAAC
CTAAACCTGATGTCAGTGGCGACATCGCCGTCTATTTCACAACCCCATCACTGGTCTATCCCGATGTGCCACGCGACCGG
GTCACGCCACCGTTTCTGCGCGATATGCTGACCGATATTGCCAATGCTCGCCAGAGTATCGATCTGGCGACATTTGAATA
CACCCTGCAACCACTGGCGGAAGCGCTGGTTGCTGCCCACCAGCGCGGGGTACAGGTGCGGCTGGCGCTTGACCGTGAAA
GCCTGGAGGACCCGGTAGATGCCAAATTCGCCGGGATTATTGAAGAAGGTGGTATTCCAATAAGCTGGGAAGAGACAACG
GCGTTTCTCCACAGCAAATTCGTTATCATTGACAACCGGATCGTCTGGACGGGATCGTGGAATGTGACGATCAACGACAC
CTACCGCAACAACAACAACCTGTTGCGGATTACCATTCCGGCCATCGTCGAAAATTATCGCGTCGAGTTTGCGGAAATGG
CCGCCGGTCGGTTCGGCAACAGCAAACAGGCAACAACCCCTCACACCCGCATCACCACCGGTCAGGCAACTATCGAAAAT
TACTTTACGCCACGCGAACGGCCAGCCGCACGGATTGTTGAGGTCATCACCAATGCCCGCCGGTCGGTCGTGTTTATGGC
CTTTTCGTTTACCAGTGACGAGATTGCCGGGGCGATGGTTAATCGGCAGCAGGCCGGTATTCCGGTACGGGGGGTGTTCG
AGCAGCGCAACGCTGAAGGGATTGGTTCCGAGTTTGGGCCGTTGCGCGAAGCAGGCGTAGAAGTTCTAGCCGATGGGAAT
TGCTATACCATGCACCACAAGGTGATCGTGGTTGATGAACGGATTGTGATCACCGGTTCGTATAACTTCACCAGCCGCGC
CGAGCGCACCAACGACGAAAACCTGCTCATCATTGAAGACCCGGTGCTGGCCGCAGCCTATCTCGGTGAGTTCGAGCGCG
TCTTTACCCAGGCTCAAAATCCAACGCGCTGCCAGTAG

Upstream 100 bases:

>100_bases
ACCCCCTTCCCCGCCGGTACCGGCGTATCCGAAGCGGTGGCTGCATGCGGTACCATTCAGCCTGCTGGCCCATCTGGGCC
GTCGCTAGACTGGGGAATCT

Downstream 100 bases:

>100_bases
GGAGTGGGAAATGGACGTTCTCAGGATTACGCCCCCCTCCCAATCTACCCCTGCTGGGGGGATGCCATTGGAGCATGATC
CTGCCCTACGCATTACCTTC

Product: phospholipase D/Transphosphatidylase

Products: NA

Alternate protein names: PLD; Choline phosphatase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MARKPSSSRPYRPNRTQIILLFLILALGYLINAGIIDLRRFGLDPALFGIETQPKPDVSGDIAVYFTTPSLVYPDVPRDR
VTPPFLRDMLTDIANARQSIDLATFEYTLQPLAEALVAAHQRGVQVRLALDRESLEDPVDAKFAGIIEEGGIPISWEETT
AFLHSKFVIIDNRIVWTGSWNVTINDTYRNNNNLLRITIPAIVENYRVEFAEMAAGRFGNSKQATTPHTRITTGQATIEN
YFTPRERPAARIVEVITNARRSVVFMAFSFTSDEIAGAMVNRQQAGIPVRGVFEQRNAEGIGSEFGPLREAGVEVLADGN
CYTMHHKVIVVDERIVITGSYNFTSRAERTNDENLLIIEDPVLAAAYLGEFERVFTQAQNPTRCQ

Sequences:

>Translated_385_residues
MARKPSSSRPYRPNRTQIILLFLILALGYLINAGIIDLRRFGLDPALFGIETQPKPDVSGDIAVYFTTPSLVYPDVPRDR
VTPPFLRDMLTDIANARQSIDLATFEYTLQPLAEALVAAHQRGVQVRLALDRESLEDPVDAKFAGIIEEGGIPISWEETT
AFLHSKFVIIDNRIVWTGSWNVTINDTYRNNNNLLRITIPAIVENYRVEFAEMAAGRFGNSKQATTPHTRITTGQATIEN
YFTPRERPAARIVEVITNARRSVVFMAFSFTSDEIAGAMVNRQQAGIPVRGVFEQRNAEGIGSEFGPLREAGVEVLADGN
CYTMHHKVIVVDERIVITGSYNFTSRAERTNDENLLIIEDPVLAAAYLGEFERVFTQAQNPTRCQ
>Mature_384_residues
ARKPSSSRPYRPNRTQIILLFLILALGYLINAGIIDLRRFGLDPALFGIETQPKPDVSGDIAVYFTTPSLVYPDVPRDRV
TPPFLRDMLTDIANARQSIDLATFEYTLQPLAEALVAAHQRGVQVRLALDRESLEDPVDAKFAGIIEEGGIPISWEETTA
FLHSKFVIIDNRIVWTGSWNVTINDTYRNNNNLLRITIPAIVENYRVEFAEMAAGRFGNSKQATTPHTRITTGQATIENY
FTPRERPAARIVEVITNARRSVVFMAFSFTSDEIAGAMVNRQQAGIPVRGVFEQRNAEGIGSEFGPLREAGVEVLADGNC
YTMHHKVIVVDERIVITGSYNFTSRAERTNDENLLIIEDPVLAAAYLGEFERVFTQAQNPTRCQ

Specific function: Could be a virulence factor [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PLD phosphodiesterase domain [H]

Homologues:

Organism=Homo sapiens, GI270265812, Length=116, Percent_Identity=41.3793103448276, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: NA

EC number: =3.1.4.4 [H]

Molecular weight: Translated: 43049; Mature: 42918

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKPSSSRPYRPNRTQIILLFLILALGYLINAGIIDLRRFGLDPALFGIETQPKPDVSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHEECCCCCCCCCCCC
DIAVYFTTPSLVYPDVPRDRVTPPFLRDMLTDIANARQSIDLATFEYTLQPLAEALVAAH
CEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHH
QRGVQVRLALDRESLEDPVDAKFAGIIEEGGIPISWEETTAFLHSKFVIIDNRIVWTGSW
HCCCEEEEEECHHHCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHEEEEEEECEEEEEECE
NVTINDTYRNNNNLLRITIPAIVENYRVEFAEMAAGRFGNSKQATTPHTRITTGQATIEN
EEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHH
YFTPRERPAARIVEVITNARRSVVFMAFSFTSDEIAGAMVNRQQAGIPVRGVFEQRNAEG
CCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHCCCCC
IGSEFGPLREAGVEVLADGNCYTMHHKVIVVDERIVITGSYNFTSRAERTNDENLLIIED
CCCCCCHHHHCCEEEEECCCEEEEEEEEEEEECEEEEEECCCCCCCCCCCCCCCEEEEEC
PVLAAAYLGEFERVFTQAQNPTRCQ
CHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ARKPSSSRPYRPNRTQIILLFLILALGYLINAGIIDLRRFGLDPALFGIETQPKPDVSG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHEECCCCCCCCCCCC
DIAVYFTTPSLVYPDVPRDRVTPPFLRDMLTDIANARQSIDLATFEYTLQPLAEALVAAH
CEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHH
QRGVQVRLALDRESLEDPVDAKFAGIIEEGGIPISWEETTAFLHSKFVIIDNRIVWTGSW
HCCCEEEEEECHHHCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHEEEEEEECEEEEEECE
NVTINDTYRNNNNLLRITIPAIVENYRVEFAEMAAGRFGNSKQATTPHTRITTGQATIEN
EEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHH
YFTPRERPAARIVEVITNARRSVVFMAFSFTSDEIAGAMVNRQQAGIPVRGVFEQRNAEG
CCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHCCCCC
IGSEFGPLREAGVEVLADGNCYTMHHKVIVVDERIVITGSYNFTSRAERTNDENLLIIED
CCCCCCHHHHCCEEEEECCCEEEEEEEEEEEECEEEEEECCCCCCCCCCCCCCCEEEEEC
PVLAAAYLGEFERVFTQAQNPTRCQ
CHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA