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The map label for this gene is mrdB [H]

Identifier: 222524039

GI number: 222524039

Start: 943353

End: 944477

Strand: Direct

Name: mrdB [H]

Synonym: Chy400_0754

Alternate gene names: 222524039

Gene position: 943353-944477 (Clockwise)

Preceding gene: 222524038

Following gene: 222524041

Centisome position: 17.9

GC content: 54.93

Gene sequence:

>1125_bases
GTGGAAACGCGGCGCTGGCGGGATCTGGATTGGGGCATTTTGGTCAGTGTAGCTGTCCTGCTGATTATTGGCAGCCTGGC
ACTCCACAGTGCAACCCTGAATGCAGTGGCCGGTAATGGCTTACCATTACGTCCGGTCTTCGGACGTCAAATCGTATATA
TCGTTGTCGGCCTGATCGCCATGGTCGCCATGATGTCGTTTGATTACCGCTTGCTTTCCAGCCTGGCGCGCCCACTCTAC
GTCAGCACAATACTACTACTGGGTGCGGTATTGGTAATCGGCCGCGTAAGTGAAGGTGCGCAGAGCTGGATTGCCATCGG
TGAACGAACGTTTCAACCTGCTGAACTGGGCAAACTCGTGCTCATCATTGCGCTGGCCACGTACTGGCAGCACTACGCTG
ATCGTGGTGGAAGCTGGCTGGTGCAGATAGGTGGATTATTGATCGCCGGTGTACCAATGGCGTTGATCTTTATCCAGCCC
GACCTGGGCACAACGCTGGTTCTGGCCGGCATCTGGCTGACGATGGCGTGGGGTGGTGGCATGCGGTTGGTCCAGTTGAT
CACCCTGTTCATTGCCGCCATCCCACTCGCATGGATCGCGTGGCACTACGTGCTCGATACCTATCAGCAAGTTCGGCTCA
GTACATTCTACTACTTGCTCACTAATCCGGCGGCTGTTGATTTTAATGCCGCTTATAACGTCATTCAGGCACTCAATGCA
ATCAGTTCCGGCGGTCTGACCGGCACCGGCCTCACCCGTGGCCTGTTCAGTCAGGGCAATTACGTGCCGGTGCAGCACAC
CGACTTCATCTTCGCTGTTATCGGCGAAGAATTAGGGTTTATCGGTGGTGTGGTGCTGATCATCTTTCAGGCGGTCGTAC
TCTGGCAGACCCTCTCTATTGCTGGCAAAGCGCGTGATCAGTTTGGCCGATTGATAGCGCTCGGTATTTTCGGGATGCTC
TTCAGTCACACCGTCATCAACATTGGCATGAACATGAGTCTCCTGCCGGTAACCGGTCTGCCATTGCCGTTCGTCTCGGC
GGGAGGCAGCTTTATGGTGACCACCCTGATCGCCATTGGCCTGTTACAAAGTATCAGTCTTCGCCACCGACATATTGCTT
TCTGA

Upstream 100 bases:

>100_bases
CAACGCCAGACATCTGACACATGGATACTGAGCACGGCAGAGATACAATACCAGCAGAGTTGTTCACGACCTGGACAACA
ACGACATAACGAGGTACCCA

Downstream 100 bases:

>100_bases
TGCAGTTTTACCGATTGTCTGATCTCACCATACACATTAACCGTATCTTGCTACTGCGCAGTGGTAGTGCGAACCAAGGC
CTCAACCTCGGCGAGCGATG

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
METRRWRDLDWGILVSVAVLLIIGSLALHSATLNAVAGNGLPLRPVFGRQIVYIVVGLIAMVAMMSFDYRLLSSLARPLY
VSTILLLGAVLVIGRVSEGAQSWIAIGERTFQPAELGKLVLIIALATYWQHYADRGGSWLVQIGGLLIAGVPMALIFIQP
DLGTTLVLAGIWLTMAWGGGMRLVQLITLFIAAIPLAWIAWHYVLDTYQQVRLSTFYYLLTNPAAVDFNAAYNVIQALNA
ISSGGLTGTGLTRGLFSQGNYVPVQHTDFIFAVIGEELGFIGGVVLIIFQAVVLWQTLSIAGKARDQFGRLIALGIFGML
FSHTVINIGMNMSLLPVTGLPLPFVSAGGSFMVTTLIAIGLLQSISLRHRHIAF

Sequences:

>Translated_374_residues
METRRWRDLDWGILVSVAVLLIIGSLALHSATLNAVAGNGLPLRPVFGRQIVYIVVGLIAMVAMMSFDYRLLSSLARPLY
VSTILLLGAVLVIGRVSEGAQSWIAIGERTFQPAELGKLVLIIALATYWQHYADRGGSWLVQIGGLLIAGVPMALIFIQP
DLGTTLVLAGIWLTMAWGGGMRLVQLITLFIAAIPLAWIAWHYVLDTYQQVRLSTFYYLLTNPAAVDFNAAYNVIQALNA
ISSGGLTGTGLTRGLFSQGNYVPVQHTDFIFAVIGEELGFIGGVVLIIFQAVVLWQTLSIAGKARDQFGRLIALGIFGML
FSHTVINIGMNMSLLPVTGLPLPFVSAGGSFMVTTLIAIGLLQSISLRHRHIAF
>Mature_374_residues
METRRWRDLDWGILVSVAVLLIIGSLALHSATLNAVAGNGLPLRPVFGRQIVYIVVGLIAMVAMMSFDYRLLSSLARPLY
VSTILLLGAVLVIGRVSEGAQSWIAIGERTFQPAELGKLVLIIALATYWQHYADRGGSWLVQIGGLLIAGVPMALIFIQP
DLGTTLVLAGIWLTMAWGGGMRLVQLITLFIAAIPLAWIAWHYVLDTYQQVRLSTFYYLLTNPAAVDFNAAYNVIQALNA
ISSGGLTGTGLTRGLFSQGNYVPVQHTDFIFAVIGEELGFIGGVVLIIFQAVVLWQTLSIAGKARDQFGRLIALGIFGML
FSHTVINIGMNMSLLPVTGLPLPFVSAGGSFMVTTLIAIGLLQSISLRHRHIAF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=328, Percent_Identity=36.5853658536585, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=32.4175824175824, Blast_Score=131, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40465; Mature: 40465

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRRWRDLDWGILVSVAVLLIIGSLALHSATLNAVAGNGLPLRPVFGRQIVYIVVGLIA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
MVAMMSFDYRLLSSLARPLYVSTILLLGAVLVIGRVSEGAQSWIAIGERTFQPAELGKLV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHH
LIIALATYWQHYADRGGSWLVQIGGLLIAGVPMALIFIQPDLGTTLVLAGIWLTMAWGGG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCH
MRLVQLITLFIAAIPLAWIAWHYVLDTYQQVRLSTFYYLLTNPAAVDFNAAYNVIQALNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEECHHHHHHHHHHHHH
ISSGGLTGTGLTRGLFSQGNYVPVQHTDFIFAVIGEELGFIGGVVLIIFQAVVLWQTLSI
HHCCCCCCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGKARDQFGRLIALGIFGMLFSHTVINIGMNMSLLPVTGLPLPFVSAGGSFMVTTLIAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCCHHHHHHHHHHH
LLQSISLRHRHIAF
HHHHHHHHHHHCCC
>Mature Secondary Structure
METRRWRDLDWGILVSVAVLLIIGSLALHSATLNAVAGNGLPLRPVFGRQIVYIVVGLIA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
MVAMMSFDYRLLSSLARPLYVSTILLLGAVLVIGRVSEGAQSWIAIGERTFQPAELGKLV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHH
LIIALATYWQHYADRGGSWLVQIGGLLIAGVPMALIFIQPDLGTTLVLAGIWLTMAWGGG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCH
MRLVQLITLFIAAIPLAWIAWHYVLDTYQQVRLSTFYYLLTNPAAVDFNAAYNVIQALNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEECHHHHHHHHHHHHH
ISSGGLTGTGLTRGLFSQGNYVPVQHTDFIFAVIGEELGFIGGVVLIIFQAVVLWQTLSI
HHCCCCCCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGKARDQFGRLIALGIFGMLFSHTVINIGMNMSLLPVTGLPLPFVSAGGSFMVTTLIAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCCHHHHHHHHHHH
LLQSISLRHRHIAF
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]