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The map label for this gene is aroF [H]

Identifier: 222524038

GI number: 222524038

Start: 942059

End: 943102

Strand: Direct

Name: aroF [H]

Synonym: Chy400_0753

Alternate gene names: 222524038

Gene position: 942059-943102 (Clockwise)

Preceding gene: 222524037

Following gene: 222524039

Centisome position: 17.88

GC content: 56.61

Gene sequence:

>1044_bases
ATGCTAGTAGTCATGGAAGCACATGCCACGGCGGAGCAGATCGAAGCGGTCTGCGCTGAAATCCGGGCGATGGGATTCAC
TCCACATCCGATGCCTGGGCCAACACGCACAGCCATCGGAATTACAGGAAATCAAGGCCCAATTGAACAGGCCGGACGAT
TACAACGGTTGCCCGGCGTGAGTCAATTGATCCGGGTCACAGCACCCTACAAACGGGTGAGCCGGGAATTCAAAGAGCTG
GACACCGTTGTCGACGTTGGTGGCATTCCCATCGGTGGATCGGGCATTACCATCATTGCCGGGCCATGTACGGTCGAAAG
CCGCGAACAGACCTTCAATGTAGCAAGAGCGGTACAGGCCGCCGGTGCAGTCATCCTCCGTGGTGGGGCCTATAAACCGC
GCACCTCACCCTATTCCTTTCAGGGATTGGGGGAGGCCGGCTTACAAATTCTGGCTGAAGCACGGGCGTTAACCGGGATG
CCGGTGGTCACGGAAGTGATGGACACCGAGACACTACCGCTCGTCGTGCAGTATGCCGACATGCTGCAAATCGGTGCGCG
CAATATGCAAAACTACTCGCTGTTGCGGGCAGTTGGGCGTACCCGCCACCCGGTACTACTCAAACGCGGCTTTGCGGCTA
CCGTGAAGGATTTGTTGCTGGCGGCAGAGTATATTCTGGCCGAAGGTAACCCAAACGTTGTTTTGTGTGAACGAGGTATT
CGCACGTTCGATGACAGTCTGCGCTTTACCCTTGATCTGGGAGCGGTGCCCTTGATCAAGCAGCTTTCGCACCTACCGGT
CATTGTTGATCCGTCGCATGCCAGTGGTCGGGCCGACATGGTGATTCCGATGGCGCGAGCTGCCATTGCTGCCGGCGCTG
ATGGTTTGATCATTGAGGTGCATGACAATCCAGCTTTTGCCGTTTGCGACGGGACACAGTCACTGGTGCCTGAGAGTTTT
GCCGATCTGATGAAGCAATTGCATCGGGTAGCAGCAGCCATCGAGCGACCTCTGGTGCGTTGTGACGTAGCTCAGACAAA
GTAG

Upstream 100 bases:

>100_bases
CAACTGGATCTACGAATAGTCGTTGTTCCGAATAACGGACACTACGTCCGTCAATGCGGTTGGCGCAACCTGATGCTTGC
CGCCAACCGCCGCCTTGTCT

Downstream 100 bases:

>100_bases
CAGTTGTTTCATAGCGCGCTGATATAGGCTTCTGCTCGTGCACAATAGACACACCTGACAATTAATAGCAGTCTAACCAT
CCGGGCAAAGTCCGGCAGGT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLVVMEAHATAEQIEAVCAEIRAMGFTPHPMPGPTRTAIGITGNQGPIEQAGRLQRLPGVSQLIRVTAPYKRVSREFKEL
DTVVDVGGIPIGGSGITIIAGPCTVESREQTFNVARAVQAAGAVILRGGAYKPRTSPYSFQGLGEAGLQILAEARALTGM
PVVTEVMDTETLPLVVQYADMLQIGARNMQNYSLLRAVGRTRHPVLLKRGFAATVKDLLLAAEYILAEGNPNVVLCERGI
RTFDDSLRFTLDLGAVPLIKQLSHLPVIVDPSHASGRADMVIPMARAAIAAGADGLIIEVHDNPAFAVCDGTQSLVPESF
ADLMKQLHRVAAAIERPLVRCDVAQTK

Sequences:

>Translated_347_residues
MLVVMEAHATAEQIEAVCAEIRAMGFTPHPMPGPTRTAIGITGNQGPIEQAGRLQRLPGVSQLIRVTAPYKRVSREFKEL
DTVVDVGGIPIGGSGITIIAGPCTVESREQTFNVARAVQAAGAVILRGGAYKPRTSPYSFQGLGEAGLQILAEARALTGM
PVVTEVMDTETLPLVVQYADMLQIGARNMQNYSLLRAVGRTRHPVLLKRGFAATVKDLLLAAEYILAEGNPNVVLCERGI
RTFDDSLRFTLDLGAVPLIKQLSHLPVIVDPSHASGRADMVIPMARAAIAAGADGLIIEVHDNPAFAVCDGTQSLVPESF
ADLMKQLHRVAAAIERPLVRCDVAQTK
>Mature_347_residues
MLVVMEAHATAEQIEAVCAEIRAMGFTPHPMPGPTRTAIGITGNQGPIEQAGRLQRLPGVSQLIRVTAPYKRVSREFKEL
DTVVDVGGIPIGGSGITIIAGPCTVESREQTFNVARAVQAAGAVILRGGAYKPRTSPYSFQGLGEAGLQILAEARALTGM
PVVTEVMDTETLPLVVQYADMLQIGARNMQNYSLLRAVGRTRHPVLLKRGFAATVKDLLLAAEYILAEGNPNVVLCERGI
RTFDDSLRFTLDLGAVPLIKQLSHLPVIVDPSHASGRADMVIPMARAAIAAGADGLIIEVHDNPAFAVCDGTQSLVPESF
ADLMKQLHRVAAAIERPLVRCDVAQTK

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=210, Percent_Identity=28.0952380952381, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 37039; Mature: 37039

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVMEAHATAEQIEAVCAEIRAMGFTPHPMPGPTRTAIGITGNQGPIEQAGRLQRLPGV
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCH
SQLIRVTAPYKRVSREFKELDTVVDVGGIPIGGSGITIIAGPCTVESREQTFNVARAVQA
HHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHH
AGAVILRGGAYKPRTSPYSFQGLGEAGLQILAEARALTGMPVVTEVMDTETLPLVVQYAD
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHH
MLQIGARNMQNYSLLRAVGRTRHPVLLKRGFAATVKDLLLAAEYILAEGNPNVVLCERGI
HHHHHHCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHEECCCCCEEEECCCC
RTFDDSLRFTLDLGAVPLIKQLSHLPVIVDPSHASGRADMVIPMARAAIAAGADGLIIEV
CHHCCCEEEEEECCCHHHHHHHHCCCEEECCCCCCCCCCEEHHHHHHHHHCCCCEEEEEE
HDNPAFAVCDGTQSLVPESFADLMKQLHRVAAAIERPLVRCDVAQTK
ECCCCEEEECCCHHHCHHHHHHHHHHHHHHHHHHHCCHHEECCCCCC
>Mature Secondary Structure
MLVVMEAHATAEQIEAVCAEIRAMGFTPHPMPGPTRTAIGITGNQGPIEQAGRLQRLPGV
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCH
SQLIRVTAPYKRVSREFKELDTVVDVGGIPIGGSGITIIAGPCTVESREQTFNVARAVQA
HHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHH
AGAVILRGGAYKPRTSPYSFQGLGEAGLQILAEARALTGMPVVTEVMDTETLPLVVQYAD
CCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHH
MLQIGARNMQNYSLLRAVGRTRHPVLLKRGFAATVKDLLLAAEYILAEGNPNVVLCERGI
HHHHHHCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHEECCCCCEEEECCCC
RTFDDSLRFTLDLGAVPLIKQLSHLPVIVDPSHASGRADMVIPMARAAIAAGADGLIIEV
CHHCCCEEEEEECCCHHHHHHHHCCCEEECCCCCCCCCCEEHHHHHHHHHCCCCEEEEEE
HDNPAFAVCDGTQSLVPESFADLMKQLHRVAAAIERPLVRCDVAQTK
ECCCCEEEECCCHHHCHHHHHHHHHHHHHHHHHHHCCHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]