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The map label for this gene is ndk

Identifier: 222524037

GI number: 222524037

Start: 941522

End: 941977

Strand: Direct

Name: ndk

Synonym: Chy400_0752

Alternate gene names: 222524037

Gene position: 941522-941977 (Clockwise)

Preceding gene: 222524036

Following gene: 222524038

Centisome position: 17.87

GC content: 58.11

Gene sequence:

>456_bases
ATGGAACGTGCACTGTTAATCTTGAAACCTGACGCCGTACAACGAGGATTGATCGGCGCTATCATCAGCCGCTTTGAACA
GCGGGGCTTGAAATTTCAGGGCCTCAAGCTGATGCAGGTCGACGAGGCTCTGGCGCGCCGCCACTACGCCGAGCACGAAG
GCAAGAGCTTCTTCAACGGTCTGGTCAGCTACATCACCTCTGCACCGGTCGTTGTGGCAGTCGTTGCCGGAAAGCCGGGC
ACCGTGGAGCTGGTGCGGGCAATGGTAGGCGCCACAAATCCGGCCAAAGCAGCACCGGGGACGATCCGGGGCGACTTTGG
AGTAGACATTGGTCGCAATCTGATTCACGCTTCGGACTCGCCGGAAAGTGGTGAGCGCGAGACAGCGATCTTCTTCCAAC
CGCACGAGCTAATTGGCGAGTGGAATCGTGCGCTCGACAACTGGATCTACGAATAG

Upstream 100 bases:

>100_bases
ATCGACAGGTAACAACCTGTCGATTTTTGTTTGTCAGCATTTTGTATGTGGTATACTGACCGCGGGAAACAGACCTGTTT
CTTAATGTTATGAGGTATCC

Downstream 100 bases:

>100_bases
TCGTTGTTCCGAATAACGGACACTACGTCCGTCAATGCGGTTGGCGCAACCTGATGCTTGCCGCCAACCGCCGCCTTGTC
TATGCTAGTAGTCATGGAAG

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MERALLILKPDAVQRGLIGAIISRFEQRGLKFQGLKLMQVDEALARRHYAEHEGKSFFNGLVSYITSAPVVVAVVAGKPG
TVELVRAMVGATNPAKAAPGTIRGDFGVDIGRNLIHASDSPESGERETAIFFQPHELIGEWNRALDNWIYE

Sequences:

>Translated_151_residues
MERALLILKPDAVQRGLIGAIISRFEQRGLKFQGLKLMQVDEALARRHYAEHEGKSFFNGLVSYITSAPVVVAVVAGKPG
TVELVRAMVGATNPAKAAPGTIRGDFGVDIGRNLIHASDSPESGERETAIFFQPHELIGEWNRALDNWIYE
>Mature_151_residues
MERALLILKPDAVQRGLIGAIISRFEQRGLKFQGLKLMQVDEALARRHYAEHEGKSFFNGLVSYITSAPVVVAVVAGKPG
TVELVRAMVGATNPAKAAPGTIRGDFGVDIGRNLIHASDSPESGERETAIFFQPHELIGEWNRALDNWIYE

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family

Homologues:

Organism=Homo sapiens, GI38045913, Length=151, Percent_Identity=50.3311258278146, Blast_Score=159, Evalue=6e-40,
Organism=Homo sapiens, GI4557797, Length=151, Percent_Identity=50.3311258278146, Blast_Score=159, Evalue=7e-40,
Organism=Homo sapiens, GI37693993, Length=150, Percent_Identity=50.6666666666667, Blast_Score=152, Evalue=1e-37,
Organism=Homo sapiens, GI66392227, Length=151, Percent_Identity=45.0331125827815, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI66392205, Length=151, Percent_Identity=45.0331125827815, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI4505409, Length=151, Percent_Identity=45.0331125827815, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI66392192, Length=151, Percent_Identity=45.0331125827815, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI66392203, Length=151, Percent_Identity=45.0331125827815, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI4826862, Length=137, Percent_Identity=48.9051094890511, Blast_Score=134, Evalue=2e-32,
Organism=Homo sapiens, GI5031951, Length=140, Percent_Identity=36.4285714285714, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI7019465, Length=146, Percent_Identity=31.5068493150685, Blast_Score=71, Evalue=3e-13,
Organism=Homo sapiens, GI37574614, Length=146, Percent_Identity=31.5068493150685, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788866, Length=138, Percent_Identity=45.6521739130435, Blast_Score=122, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17506807, Length=150, Percent_Identity=44.6666666666667, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71995094, Length=131, Percent_Identity=31.2977099236641, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322783, Length=150, Percent_Identity=49.3333333333333, Blast_Score=157, Evalue=6e-40,
Organism=Drosophila melanogaster, GI45549037, Length=150, Percent_Identity=50, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NDK_CHLAA (A9WFJ8)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001634325.1
- ProteinModelPortal:   A9WFJ8
- SMR:   A9WFJ8
- GeneID:   5828681
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_0697
- HOGENOM:   HBG445152
- OMA:   ERPFFGA
- ProtClustDB:   PRK00668
- GO:   GO:0005737
- HAMAP:   MF_00451
- InterPro:   IPR001564
- InterPro:   IPR023005
- Gene3D:   G3DSA:3.30.70.141
- PANTHER:   PTHR11349
- PRINTS:   PR01243
- SMART:   SM00562

Pfam domain/function: PF00334 NDK; SSF54919 NDK

EC number: =2.7.4.6

Molecular weight: Translated: 16555; Mature: 16555

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00469 NDP_KINASES

Important sites: ACT_SITE 116-116 BINDING 9-9 BINDING 57-57 BINDING 86-86 BINDING 92-92 BINDING 103-103 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERALLILKPDAVQRGLIGAIISRFEQRGLKFQGLKLMQVDEALARRHYAEHEGKSFFNG
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHH
LVSYITSAPVVVAVVAGKPGTVELVRAMVGATNPAKAAPGTIRGDFGVDIGRNLIHASDS
HHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
PESGERETAIFFQPHELIGEWNRALDNWIYE
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERALLILKPDAVQRGLIGAIISRFEQRGLKFQGLKLMQVDEALARRHYAEHEGKSFFNG
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHH
LVSYITSAPVVVAVVAGKPGTVELVRAMVGATNPAKAAPGTIRGDFGVDIGRNLIHASDS
HHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
PESGERETAIFFQPHELIGEWNRALDNWIYE
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA