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The map label for this gene is ykhA [H]

Identifier: 222523861

GI number: 222523861

Start: 681088

End: 681594

Strand: Direct

Name: ykhA [H]

Synonym: Chy400_0569

Alternate gene names: 222523861

Gene position: 681088-681594 (Clockwise)

Preceding gene: 222523860

Following gene: 222523862

Centisome position: 12.93

GC content: 57.4

Gene sequence:

>507_bases
ATGGATAACACAACGTTCCCTAACCGGCCGGCGCGGGCGGCAAATGAAGAACGCATGGCCGAAATTATCTTGCCTCATCA
AACCAACGGCTACGGTACCATGTTTGGTGGTGATGTGATGGCACTGATGGATAAAGCGGCAGCGATTGCCGCTCTCCGCT
TCTGTCGCTTGCCGGTTGTAACCGCCTCGACCGAACGGATTGATTTTCGGACCCCGATTGGGCAGGGCGAAATTGTGGAA
GCCTTCTCGCGGGTGATCTACGTTGGGCGGAGTTCCATGGTGGTGCGCGTACACCTCTTTGCCGAACATCCGCTGATCGG
AGATCGCCGGCTCTGCACGACCGGCTATTTCAGCATGGTAGCCATCAACCGCGAAGGTGGGCCGGCGCCAGTTGTGCCAC
AATTGTTGTTGCTCGACGATGATGCCCGCGCAGAGCATGCCGTTGGTGCCGAGATTCACGCTGCTATCGCTGCACGTCGC
AATAGCCGAACAACAGGACGATCATGA

Upstream 100 bases:

>100_bases
GGGTGCATCCCGGCCATTGCTACCTCTGGAAAGAGCATAATCCTACAGCCAGTGACGGCGCTCGCATGAGCGCCGTTCGC
TACCTACAGGTTGGTGTGAT

Downstream 100 bases:

>100_bases
TCGACGAATCACTTTTTCGCCAAACGATGAGTCACTTCGCCTCCGGTGTCACTGTGGTGACGACTGCGCTCGGTGAACGC
CTGGCCGGCTTAACAGTCAG

Product: thioesterase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MDNTTFPNRPARAANEERMAEIILPHQTNGYGTMFGGDVMALMDKAAAIAALRFCRLPVVTASTERIDFRTPIGQGEIVE
AFSRVIYVGRSSMVVRVHLFAEHPLIGDRRLCTTGYFSMVAINREGGPAPVVPQLLLLDDDARAEHAVGAEIHAAIAARR
NSRTTGRS

Sequences:

>Translated_168_residues
MDNTTFPNRPARAANEERMAEIILPHQTNGYGTMFGGDVMALMDKAAAIAALRFCRLPVVTASTERIDFRTPIGQGEIVE
AFSRVIYVGRSSMVVRVHLFAEHPLIGDRRLCTTGYFSMVAINREGGPAPVVPQLLLLDDDARAEHAVGAEIHAAIAARR
NSRTTGRS
>Mature_168_residues
MDNTTFPNRPARAANEERMAEIILPHQTNGYGTMFGGDVMALMDKAAAIAALRFCRLPVVTASTERIDFRTPIGQGEIVE
AFSRVIYVGRSSMVVRVHLFAEHPLIGDRRLCTTGYFSMVAINREGGPAPVVPQLLLLDDDARAEHAVGAEIHAAIAARR
NSRTTGRS

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528286, Length=150, Percent_Identity=27.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI32528284, Length=150, Percent_Identity=27.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI75709208, Length=150, Percent_Identity=27.3333333333333, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI32528282, Length=150, Percent_Identity=27.3333333333333, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787506, Length=109, Percent_Identity=33.0275229357798, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 18319; Mature: 18319

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTTFPNRPARAANEERMAEIILPHQTNGYGTMFGGDVMALMDKAAAIAALRFCRLPVV
CCCCCCCCCCCCCCCHHHHEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCEE
TASTERIDFRTPIGQGEIVEAFSRVIYVGRSSMVVRVHLFAEHPLIGDRRLCTTGYFSMV
ECCCCCEEEECCCCCCHHHHHHHHHEEECCCCEEEEEEEEECCCCCCCCEEEECCCEEEE
AINREGGPAPVVPQLLLLDDDARAEHAVGAEIHAAIAARRNSRTTGRS
EEECCCCCCCCCCEEEEECCCCCCHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDNTTFPNRPARAANEERMAEIILPHQTNGYGTMFGGDVMALMDKAAAIAALRFCRLPVV
CCCCCCCCCCCCCCCHHHHEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCEE
TASTERIDFRTPIGQGEIVEAFSRVIYVGRSSMVVRVHLFAEHPLIGDRRLCTTGYFSMV
ECCCCCEEEECCCCCCHHHHHHHHHEEECCCCEEEEEEEEECCCCCCCCEEEECCCEEEE
AINREGGPAPVVPQLLLLDDDARAEHAVGAEIHAAIAARRNSRTTGRS
EEECCCCCCCCCCEEEEECCCCCCHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751 [H]