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The map label for this gene is glmS [H]

Identifier: 222523794

GI number: 222523794

Start: 599750

End: 601612

Strand: Direct

Name: glmS [H]

Synonym: Chy400_0502

Alternate gene names: 222523794

Gene position: 599750-601612 (Clockwise)

Preceding gene: 222523793

Following gene: 222523803

Centisome position: 11.38

GC content: 56.52

Gene sequence:

>1863_bases
ATGTGTGGTATTGTGGGCTATATTGGTGGACGTGAGGCGACCGAAGTTGTGCTGAATGGCCTTCAACGATTGGAATATCG
GGGTTACGATTCGGCGGGGATCGCTATCTACCATCCAGATGCCGGGTTGCAGTTGCGTCGCAGTGTTGGCAAGCTCATCA
ATTTGCAACAACGGGTGCAGGCCGATCCACCGCGTGGCCGGGTCGGCATTGGTCATACGCGCTGGGCCACGCATGGTGGC
GTCACCGAGCAAAATGCTCACCCCCACCGTGATGCCAGTGGCACGATTGTGGTGATTCAAAATGGGATTGTTGAGAATTA
TCTAAGCCTGAAGGGGCGTCTGATCGAATTGGGGTACCAGTTTGAGTCGCAGACCGATACTGAAGTGATTGCAAAGCTGA
TTGGACATTACTATCAAGAGCAGCGTGATCTGGTCGCGGCCACACGTCAGGCGTTGCAGGAACTACGCGGTGGCAATGCG
GTTGTCGCCTTTTGTATTCACGAGCCGGACACGCTGGTTGCAGCGCGCCTGGGCAACGCCGGTGGCATCGCGATTGGGCT
TGGCGACAACGAACAGTTTATCGCTTCCGATATTCCGGCTATCCTCGATTACACACGCAATCTGATCTTTCTGGAAGACC
ATGACATTGCCGTTGTCCGGCGTGACGAGGTAACGATTACCCGGCTCGATGGTACACCGGTTACGCGCGCAGTACACAGT
ATTGCCTGGGACCCCGTGGCGGCAGCGAAAGGTGATTATCGCCACTTTATGCACAAAGAGATCGATGAACAACCACGGGC
GCTGATGGATGTGTTGCGCGGACGGATCGATCAGGAGCGTGGTCTGATCACGCTCGAAGACCTCCGCCTCGACGATCAGG
ACTTACGTCGGGTCCGTCGTATCTACGCTATCGCGTGCGGTACGGCGTGGCACGCCGCCTTGGTGGCGAAGTTTATGATT
GAGAATCTGGCACGAGTGCGGGTTGAAGTCGACTATGCCAGCGAGTTCCGCTATCGCCAGCCGATATTGCAGAGCAATGG
TGAGCGCGATGCGCTGATTCTTACCTTCACGCAAAGCGGTGAAACAGTCGATACGCTGGCCGGCATGGAAGAGGCACGCA
GACAGGGCGTTCCCAGTGTAGCAATCGTTAATGCCATCGGCAGTCAGGCCGCCCGGCTGGCCGATGGCGGCCCGATCTAT
CTGCACGCCGGGCCAGAAATTGGGGTCGCTTCGACCAAAGCCTTTACCTCGATGCTGGTTGCAGGCTACCTGTTTGCACT
ACGTCTGGCGCAGGCGCACGGGACACTGACACCGGCCCAGATTCGGGAACATATTCAGGCGCTGGTGGAATTGCCGGGGA
AGGCGGCGCAGGTGATCGAGCAAGTCACGCCTGTATGTGTCGAGTTAGCCGAGCGCTACTATCGGGTTGGCAATGCCCTC
TTCCTGGGTCGTCAAATCAACTACCCAATCGCGCTCGAAGGCGCGCTCAAACTCAAAGAGATCAGCTACATTCACGCCGA
AGGCTACCCGGCAGGCGAAATGAAGCACGGGCCAATTGCCTTGATCGATGAGGGTATGCCGGTTGTCTGCATTGCTACCC
GCGACCACATTTACGAAAAGATGATCAGTAACGTCGAACAGGTGCGTGCGCGTCACGGCCAGGTGATTGCAATCGGTCAC
GAGGGTGATGAGTTGTTGGCGGCAAAGGCGAATCATTTCATCGGGGTACCGGCGACATTACCACTACTCCAACCGGTGTT
GAATGTGATACCGTTGCAGATCTTTGCTTATCACGTTGCCGTGTTGCGCGGGTGTGATGTCGATCAGCCGCGTAATCTGG
CCAAGAGTGTGACTGTGGAGTAG

Upstream 100 bases:

>100_bases
CACGGTAGCAGGTCTGGCTGCTGCACTCTGTCGCAGGCGGCGGCTGCCATGGGCTGCTATGGATTGTCTTTGCTTTCTTT
ACTATGAAGGAGTTTCTGCT

Downstream 100 bases:

>100_bases
GCGTTATCGAGAGCACGTTGCCGGATAACACTCCTTCCGCACGCTGCACGATGTGCTTCCGGGTTGCAGCGTGCGGAAGC
CGTGCCGCCACACTCCATAC

Product: glucosamine/fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MCGIVGYIGGREATEVVLNGLQRLEYRGYDSAGIAIYHPDAGLQLRRSVGKLINLQQRVQADPPRGRVGIGHTRWATHGG
VTEQNAHPHRDASGTIVVIQNGIVENYLSLKGRLIELGYQFESQTDTEVIAKLIGHYYQEQRDLVAATRQALQELRGGNA
VVAFCIHEPDTLVAARLGNAGGIAIGLGDNEQFIASDIPAILDYTRNLIFLEDHDIAVVRRDEVTITRLDGTPVTRAVHS
IAWDPVAAAKGDYRHFMHKEIDEQPRALMDVLRGRIDQERGLITLEDLRLDDQDLRRVRRIYAIACGTAWHAALVAKFMI
ENLARVRVEVDYASEFRYRQPILQSNGERDALILTFTQSGETVDTLAGMEEARRQGVPSVAIVNAIGSQAARLADGGPIY
LHAGPEIGVASTKAFTSMLVAGYLFALRLAQAHGTLTPAQIREHIQALVELPGKAAQVIEQVTPVCVELAERYYRVGNAL
FLGRQINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALIDEGMPVVCIATRDHIYEKMISNVEQVRARHGQVIAIGH
EGDELLAAKANHFIGVPATLPLLQPVLNVIPLQIFAYHVAVLRGCDVDQPRNLAKSVTVE

Sequences:

>Translated_620_residues
MCGIVGYIGGREATEVVLNGLQRLEYRGYDSAGIAIYHPDAGLQLRRSVGKLINLQQRVQADPPRGRVGIGHTRWATHGG
VTEQNAHPHRDASGTIVVIQNGIVENYLSLKGRLIELGYQFESQTDTEVIAKLIGHYYQEQRDLVAATRQALQELRGGNA
VVAFCIHEPDTLVAARLGNAGGIAIGLGDNEQFIASDIPAILDYTRNLIFLEDHDIAVVRRDEVTITRLDGTPVTRAVHS
IAWDPVAAAKGDYRHFMHKEIDEQPRALMDVLRGRIDQERGLITLEDLRLDDQDLRRVRRIYAIACGTAWHAALVAKFMI
ENLARVRVEVDYASEFRYRQPILQSNGERDALILTFTQSGETVDTLAGMEEARRQGVPSVAIVNAIGSQAARLADGGPIY
LHAGPEIGVASTKAFTSMLVAGYLFALRLAQAHGTLTPAQIREHIQALVELPGKAAQVIEQVTPVCVELAERYYRVGNAL
FLGRQINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALIDEGMPVVCIATRDHIYEKMISNVEQVRARHGQVIAIGH
EGDELLAAKANHFIGVPATLPLLQPVLNVIPLQIFAYHVAVLRGCDVDQPRNLAKSVTVE
>Mature_620_residues
MCGIVGYIGGREATEVVLNGLQRLEYRGYDSAGIAIYHPDAGLQLRRSVGKLINLQQRVQADPPRGRVGIGHTRWATHGG
VTEQNAHPHRDASGTIVVIQNGIVENYLSLKGRLIELGYQFESQTDTEVIAKLIGHYYQEQRDLVAATRQALQELRGGNA
VVAFCIHEPDTLVAARLGNAGGIAIGLGDNEQFIASDIPAILDYTRNLIFLEDHDIAVVRRDEVTITRLDGTPVTRAVHS
IAWDPVAAAKGDYRHFMHKEIDEQPRALMDVLRGRIDQERGLITLEDLRLDDQDLRRVRRIYAIACGTAWHAALVAKFMI
ENLARVRVEVDYASEFRYRQPILQSNGERDALILTFTQSGETVDTLAGMEEARRQGVPSVAIVNAIGSQAARLADGGPIY
LHAGPEIGVASTKAFTSMLVAGYLFALRLAQAHGTLTPAQIREHIQALVELPGKAAQVIEQVTPVCVELAERYYRVGNAL
FLGRQINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALIDEGMPVVCIATRDHIYEKMISNVEQVRARHGQVIAIGH
EGDELLAAKANHFIGVPATLPLLQPVLNVIPLQIFAYHVAVLRGCDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=693, Percent_Identity=37.9509379509379, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI205277386, Length=689, Percent_Identity=37.4455732946299, Blast_Score=416, Evalue=1e-116,
Organism=Escherichia coli, GI1790167, Length=622, Percent_Identity=45.1768488745981, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1788651, Length=175, Percent_Identity=27.4285714285714, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532899, Length=727, Percent_Identity=33.7001375515818, Blast_Score=360, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI17532897, Length=440, Percent_Identity=39.0909090909091, Blast_Score=302, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17539970, Length=437, Percent_Identity=39.8169336384439, Blast_Score=301, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6322745, Length=442, Percent_Identity=41.1764705882353, Blast_Score=321, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6323731, Length=434, Percent_Identity=32.4884792626728, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6323730, Length=199, Percent_Identity=37.6884422110553, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21357745, Length=701, Percent_Identity=37.2325249643367, Blast_Score=427, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 68087; Mature: 68087

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYIGGREATEVVLNGLQRLEYRGYDSAGIAIYHPDAGLQLRRSVGKLINLQQRVQ
CCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHCHHHHHC
ADPPRGRVGIGHTRWATHGGVTEQNAHPHRDASGTIVVIQNGIVENYLSLKGRLIELGYQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCEEEEEEEC
FESQTDTEVIAKLIGHYYQEQRDLVAATRQALQELRGGNAVVAFCIHEPDTLVAARLGNA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHHCCCC
GGIAIGLGDNEQFIASDIPAILDYTRNLIFLEDHDIAVVRRDEVTITRLDGTPVTRAVHS
CCEEEEECCCCCCHHHCCHHHHHHCCCEEEEECCCEEEEEECCEEEEEECCCHHHHHHHH
IAWDPVAAAKGDYRHFMHKEIDEQPRALMDVLRGRIDQERGLITLEDLRLDDQDLRRVRR
HCCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHH
IYAIACGTAWHAALVAKFMIENLARVRVEVDYASEFRYRQPILQSNGERDALILTFTQSG
HHHHHCCHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHCCHHHCCCCCCEEEEEEECCC
ETVDTLAGMEEARRQGVPSVAIVNAIGSQAARLADGGPIYLHAGPEIGVASTKAFTSMLV
CHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
AGYLFALRLAQAHGTLTPAQIREHIQALVELPGKAAQVIEQVTPVCVELAERYYRVGNAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
FLGRQINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALIDEGMPVVCIATRDHIYEK
EECCCCCCCEEECCCEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECHHHHHHH
MISNVEQVRARHGQVIAIGHEGDELLAAKANHFIGVPATLPLLQPVLNVIPLQIFAYHVA
HHHHHHHHHHHCCCEEEEECCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
VLRGCDVDQPRNLAKSVTVE
HHHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYIGGREATEVVLNGLQRLEYRGYDSAGIAIYHPDAGLQLRRSVGKLINLQQRVQ
CCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHCHHHHHC
ADPPRGRVGIGHTRWATHGGVTEQNAHPHRDASGTIVVIQNGIVENYLSLKGRLIELGYQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCEEEEEEEC
FESQTDTEVIAKLIGHYYQEQRDLVAATRQALQELRGGNAVVAFCIHEPDTLVAARLGNA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHHCCCC
GGIAIGLGDNEQFIASDIPAILDYTRNLIFLEDHDIAVVRRDEVTITRLDGTPVTRAVHS
CCEEEEECCCCCCHHHCCHHHHHHCCCEEEEECCCEEEEEECCEEEEEECCCHHHHHHHH
IAWDPVAAAKGDYRHFMHKEIDEQPRALMDVLRGRIDQERGLITLEDLRLDDQDLRRVRR
HCCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHH
IYAIACGTAWHAALVAKFMIENLARVRVEVDYASEFRYRQPILQSNGERDALILTFTQSG
HHHHHCCHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHCCHHHCCCCCCEEEEEEECCC
ETVDTLAGMEEARRQGVPSVAIVNAIGSQAARLADGGPIYLHAGPEIGVASTKAFTSMLV
CHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
AGYLFALRLAQAHGTLTPAQIREHIQALVELPGKAAQVIEQVTPVCVELAERYYRVGNAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
FLGRQINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALIDEGMPVVCIATRDHIYEK
EECCCCCCCEEECCCEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECHHHHHHH
MISNVEQVRARHGQVIAIGHEGDELLAAKANHFIGVPATLPLLQPVLNVIPLQIFAYHVA
HHHHHHHHHHHCCCEEEEECCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
VLRGCDVDQPRNLAKSVTVE
HHHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA