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The map label for this gene is soxB [H]

Identifier: 222523745

GI number: 222523745

Start: 549312

End: 550469

Strand: Direct

Name: soxB [H]

Synonym: Chy400_0451

Alternate gene names: 222523745

Gene position: 549312-550469 (Clockwise)

Preceding gene: 222523744

Following gene: 222523746

Centisome position: 10.43

GC content: 57.6

Gene sequence:

>1158_bases
ATGATTGAGCGGGCACAAGTGGTTATTATTGGTGCAGGTGTAATCGGCGCCAGTATTGCTTTTCATCTGGCCGAACGTGG
CCTGCGCGACGTGATCATCCTGGAGCGTGAAGAGACCGAAATCAGCGGTAGTACGGCCCGCTCGGCGGCGGGAGTGCGCC
ATCAATTTTCATCGCGTACCAATGTGCTGTTGTCACGCTATAGCATCGAGCGTTTACGCCATTTCGAGGAAGAAGTTGGT
GGTCACGCCGAATTACGTCAAGTTGGCTACCTGTTTTTGATCAACGACGAGCAGACCTGGGCGCAATACATGCGCAACGT
GGCGATGCAGCGCGAGTTGGGGGTGCGGGTCGAGGTTTTAACCCCCGCTGAAGCAGCCCGCTTCATCCCGCAGATGCGGA
CTGACGATCTGATCGGTGCCACGTTTGGCCCCGATGACGGATACTGCGATCCTTACGGTATCGCCCTGGGTTATCTGCGT
GCTGCGCAGCGCCACGGCGTGCGATTGTACCGGGGGAGACCGGTCACCGGCTTTCACATCCAGGGTGGTCGGGTGACGGC
AGTTGAAACACCAGCCGGTACGGTGGGTTGTGAGTTCGTGATCAACTGCGCTGGACCGTGGGCCGGTGAAGTCGCCGCCC
TGGCAGGTCTTGATCTGCCGGTACGACCATACCGACGGAATGTGTATATGACGACACCCTTCCCGGCGATCAGTGCCCCA
ATTCCACTGACGATAGATGTAGGCAGCGGTTTCTATATGCGGCGCGAGGGGCAGAGCATTCTGATGGGGCGGTCAAACCC
CAATGAGCCAAGCAGTACCAACACAAATGTGGACTGGGACTGGTTGGAGGCAGTGATCGAGGCCGGTATCCACCGCTTCC
CCATTCTCGAAACAGCCGGGCTGGCCGAGCAGCAGTGCTGGGCCGGGTTGTACGAGATTACGCCTGATCATAACCCGATT
CTCGGTCGTCACCCCGATCTGGCCGGTTACATTGATGCCAGTGGGTTTAGCGGTCACGGCATTATGCACGCACCGGCTAC
GGGCTTACTCATCGCTGAAGAGGTGATCGACGGTCGAGCACATACGATCAACATCGACGAATTGCGGATCGACCGATTCC
GCAGTGGTCATCTGGCATCCGAATTTAATGTGATTTAG

Upstream 100 bases:

>100_bases
CGTGAAAAGCGGGGTAAGGTATAGCACGTGAACGATGCATTGAAAAACGTAAAAACAAAGGACGCGCCAATGGCGGCGCA
CATCAGGCGAGGTGAGATGT

Downstream 100 bases:

>100_bases
CGAGGTGATTTCCAATGACACTCGATGAAGCAATTGCCGAGATCAAGCGCCGGATTGCCGAGGTTAGTCCCAGCGCAGTC
ACGCGCGTCACCCGGGTTTC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MIERAQVVIIGAGVIGASIAFHLAERGLRDVIILEREETEISGSTARSAAGVRHQFSSRTNVLLSRYSIERLRHFEEEVG
GHAELRQVGYLFLINDEQTWAQYMRNVAMQRELGVRVEVLTPAEAARFIPQMRTDDLIGATFGPDDGYCDPYGIALGYLR
AAQRHGVRLYRGRPVTGFHIQGGRVTAVETPAGTVGCEFVINCAGPWAGEVAALAGLDLPVRPYRRNVYMTTPFPAISAP
IPLTIDVGSGFYMRREGQSILMGRSNPNEPSSTNTNVDWDWLEAVIEAGIHRFPILETAGLAEQQCWAGLYEITPDHNPI
LGRHPDLAGYIDASGFSGHGIMHAPATGLLIAEEVIDGRAHTINIDELRIDRFRSGHLASEFNVI

Sequences:

>Translated_385_residues
MIERAQVVIIGAGVIGASIAFHLAERGLRDVIILEREETEISGSTARSAAGVRHQFSSRTNVLLSRYSIERLRHFEEEVG
GHAELRQVGYLFLINDEQTWAQYMRNVAMQRELGVRVEVLTPAEAARFIPQMRTDDLIGATFGPDDGYCDPYGIALGYLR
AAQRHGVRLYRGRPVTGFHIQGGRVTAVETPAGTVGCEFVINCAGPWAGEVAALAGLDLPVRPYRRNVYMTTPFPAISAP
IPLTIDVGSGFYMRREGQSILMGRSNPNEPSSTNTNVDWDWLEAVIEAGIHRFPILETAGLAEQQCWAGLYEITPDHNPI
LGRHPDLAGYIDASGFSGHGIMHAPATGLLIAEEVIDGRAHTINIDELRIDRFRSGHLASEFNVI
>Mature_385_residues
MIERAQVVIIGAGVIGASIAFHLAERGLRDVIILEREETEISGSTARSAAGVRHQFSSRTNVLLSRYSIERLRHFEEEVG
GHAELRQVGYLFLINDEQTWAQYMRNVAMQRELGVRVEVLTPAEAARFIPQMRTDDLIGATFGPDDGYCDPYGIALGYLR
AAQRHGVRLYRGRPVTGFHIQGGRVTAVETPAGTVGCEFVINCAGPWAGEVAALAGLDLPVRPYRRNVYMTTPFPAISAP
IPLTIDVGSGFYMRREGQSILMGRSNPNEPSSTNTNVDWDWLEAVIEAGIHRFPILETAGLAEQQCWAGLYEITPDHNPI
LGRHPDLAGYIDASGFSGHGIMHAPATGLLIAEEVIDGRAHTINIDELRIDRFRSGHLASEFNVI

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=370, Percent_Identity=32.972972972973, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI21361378, Length=370, Percent_Identity=32.972972972973, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI8923708, Length=415, Percent_Identity=32.5301204819277, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI194306651, Length=387, Percent_Identity=27.390180878553, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI24797151, Length=391, Percent_Identity=26.5984654731458, Blast_Score=141, Evalue=9e-34,
Organism=Escherichia coli, GI1787298, Length=394, Percent_Identity=23.0964467005076, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541536, Length=428, Percent_Identity=28.2710280373832, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71994045, Length=393, Percent_Identity=24.9363867684478, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994052, Length=400, Percent_Identity=24.5, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI20129729, Length=414, Percent_Identity=31.4009661835749, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI28571104, Length=394, Percent_Identity=27.6649746192893, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI20130091, Length=368, Percent_Identity=27.7173913043478, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17985989, Length=413, Percent_Identity=28.0871670702179, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42311; Mature: 42311

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIERAQVVIIGAGVIGASIAFHLAERGLRDVIILEREETEISGSTARSAAGVRHQFSSRT
CCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCHH
NVLLSRYSIERLRHFEEEVGGHAELRQVGYLFLINDEQTWAQYMRNVAMQRELGVRVEVL
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHCCEEEEE
TPAEAARFIPQMRTDDLIGATFGPDDGYCDPYGIALGYLRAAQRHGVRLYRGRPVTGFHI
CCHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEEE
QGGRVTAVETPAGTVGCEFVINCAGPWAGEVAALAGLDLPVRPYRRNVYMTTPFPAISAP
CCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCCCC
IPLTIDVGSGFYMRREGQSILMGRSNPNEPSSTNTNVDWDWLEAVIEAGIHRFPILETAG
CEEEEECCCCEEEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
LAEQQCWAGLYEITPDHNPILGRHPDLAGYIDASGFSGHGIMHAPATGLLIAEEVIDGRA
CCHHHHHCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCEEEEHHHHCCCC
HTINIDELRIDRFRSGHLASEFNVI
EEEEHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIERAQVVIIGAGVIGASIAFHLAERGLRDVIILEREETEISGSTARSAAGVRHQFSSRT
CCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCHH
NVLLSRYSIERLRHFEEEVGGHAELRQVGYLFLINDEQTWAQYMRNVAMQRELGVRVEVL
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHCCEEEEE
TPAEAARFIPQMRTDDLIGATFGPDDGYCDPYGIALGYLRAAQRHGVRLYRGRPVTGFHI
CCHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEEE
QGGRVTAVETPAGTVGCEFVINCAGPWAGEVAALAGLDLPVRPYRRNVYMTTPFPAISAP
CCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCCCC
IPLTIDVGSGFYMRREGQSILMGRSNPNEPSSTNTNVDWDWLEAVIEAGIHRFPILETAG
CEEEEECCCCEEEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
LAEQQCWAGLYEITPDHNPILGRHPDLAGYIDASGFSGHGIMHAPATGLLIAEEVIDGRA
CCHHHHHCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCEEEEHHHHCCCC
HTINIDELRIDRFRSGHLASEFNVI
EEEEHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]