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The map label for this gene is btuC [H]

Identifier: 222523632

GI number: 222523632

Start: 403346

End: 404428

Strand: Direct

Name: btuC [H]

Synonym: Chy400_0338

Alternate gene names: 222523632

Gene position: 403346-404428 (Clockwise)

Preceding gene: 222523631

Following gene: 222523633

Centisome position: 7.66

GC content: 52.54

Gene sequence:

>1083_bases
ATGACAAAAACACTCTCAGCAGCGATACAATCTACACGATGGCCACGGCCAGGCTTGCAACCGTTGGTTCTACTGGCAAT
GGTTGGCGTGACGCTATGCATCTTTTTGCTGAGTCTTAGTTTAGGATCGGTATCTATCCCACCCGAACAGGTGTTGAGTA
TTCTCTTGTACCAGGAGGCCGAACGGAAATCCTGGGTCACAATCATTTATGATTTTCGTCTTCCCAAAGCACTGACCGCC
GCGCTGGCCGGTGCTGCGCTTGGTGTTAGCGGCTTGCAGATGCAGACCCTGTTTCGCAACCCTCTGGCCGATCCGTTCGT
TCTCGGCATTAGTTCAGGTGCCAGTCTGGGAGTAGCCATCGTTGTACTGAGTGTTGGTGCGGCAAACACAGCACTCCTCG
CAGTTGCCGGCCTACTCGGTAACGTGAGCCTGGTAGTTGCCGCCAGTCTCGGCGCCGGTATGGTTATGATGATTATTCTC
ACCCTCGCTCAACGAGTGCGGAGTAGCATCACCTTACTTATCCTGGGTCTGATGATAGGCTATGTAACCAGTGCTGTGGT
CAGTCTCCTGCTGTACTTCAGTATCGCTGAGCGTATTCAGGCCTACATCGCCTGGAGCTTTGGCAACTTTGGTGGGGTAA
CATGGAGCCAGATGCAGGTACTGGCACCGACCATCGGAATAGGGTTAATACTGGCATTACTCCTGACAAAAGTACTTAAC
GCCCTGCTGCTAGGCGAGGCATACGCACGCAGTATGGGTATGGATATTCAACTGGCGAGATGTGGTATTGTCCTGAGCAG
TTCTGTCCTCGCTGGTACAATCACCGCATTCTGTGGCCCAATTGCATTTCTCGGCATTGCCATTCCTCATCTCTGTCGAG
CACTATTCCGCACCGCCGATCATCGTATTCTGCTCCCTGCCTGTATGTGGATTGGAGCAACAATCGCCCTGCTTGGTGAT
TTGATCGCCCAGGTGCCAGGCTATAGTATCGTCTTACCGCTCAATGCCATCAACGCACTCTTCGGTGCACCCATCGTTAT
GTGGGTCGTTCTGCAACGGTATCGAGGAGTTTTTGGGTTATGA

Upstream 100 bases:

>100_bases
TCGAACGCATCGTGCGTGAGCATCTGGTGCAAAACAGACCGGTAGTTGAGCATATCTTCCACCAGTTGCATGAGCAGTGA
GTAAGAATAGAGAGATGAGC

Downstream 100 bases:

>100_bases
GCCGCTCCATTCTGGTTACCGAACATCTCCGTATTGGCTATGCCAATCGGCGTGGAGAGGCACGAGTGGTTGCAGATCAA
CTCAACCTGACCCTCAATGA

Product: transport system permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTKTLSAAIQSTRWPRPGLQPLVLLAMVGVTLCIFLLSLSLGSVSIPPEQVLSILLYQEAERKSWVTIIYDFRLPKALTA
ALAGAALGVSGLQMQTLFRNPLADPFVLGISSGASLGVAIVVLSVGAANTALLAVAGLLGNVSLVVAASLGAGMVMMIIL
TLAQRVRSSITLLILGLMIGYVTSAVVSLLLYFSIAERIQAYIAWSFGNFGGVTWSQMQVLAPTIGIGLILALLLTKVLN
ALLLGEAYARSMGMDIQLARCGIVLSSSVLAGTITAFCGPIAFLGIAIPHLCRALFRTADHRILLPACMWIGATIALLGD
LIAQVPGYSIVLPLNAINALFGAPIVMWVVLQRYRGVFGL

Sequences:

>Translated_360_residues
MTKTLSAAIQSTRWPRPGLQPLVLLAMVGVTLCIFLLSLSLGSVSIPPEQVLSILLYQEAERKSWVTIIYDFRLPKALTA
ALAGAALGVSGLQMQTLFRNPLADPFVLGISSGASLGVAIVVLSVGAANTALLAVAGLLGNVSLVVAASLGAGMVMMIIL
TLAQRVRSSITLLILGLMIGYVTSAVVSLLLYFSIAERIQAYIAWSFGNFGGVTWSQMQVLAPTIGIGLILALLLTKVLN
ALLLGEAYARSMGMDIQLARCGIVLSSSVLAGTITAFCGPIAFLGIAIPHLCRALFRTADHRILLPACMWIGATIALLGD
LIAQVPGYSIVLPLNAINALFGAPIVMWVVLQRYRGVFGL
>Mature_359_residues
TKTLSAAIQSTRWPRPGLQPLVLLAMVGVTLCIFLLSLSLGSVSIPPEQVLSILLYQEAERKSWVTIIYDFRLPKALTAA
LAGAALGVSGLQMQTLFRNPLADPFVLGISSGASLGVAIVVLSVGAANTALLAVAGLLGNVSLVVAASLGAGMVMMIILT
LAQRVRSSITLLILGLMIGYVTSAVVSLLLYFSIAERIQAYIAWSFGNFGGVTWSQMQVLAPTIGIGLILALLLTKVLNA
LLLGEAYARSMGMDIQLARCGIVLSSSVLAGTITAFCGPIAFLGIAIPHLCRALFRTADHRILLPACMWIGATIALLGDL
IAQVPGYSIVLPLNAINALFGAPIVMWVVLQRYRGVFGL

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=35.5400696864112, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790740, Length=320, Percent_Identity=29.0625, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786805, Length=325, Percent_Identity=32.6153846153846, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790741, Length=289, Percent_Identity=29.757785467128, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786804, Length=259, Percent_Identity=31.6602316602317, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786347, Length=311, Percent_Identity=27.0096463022508, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37857; Mature: 37726

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTLSAAIQSTRWPRPGLQPLVLLAMVGVTLCIFLLSLSLGSVSIPPEQVLSILLYQEA
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ERKSWVTIIYDFRLPKALTAALAGAALGVSGLQMQTLFRNPLADPFVLGISSGASLGVAI
CCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
VVLSVGAANTALLAVAGLLGNVSLVVAASLGAGMVMMIILTLAQRVRSSITLLILGLMIG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVTSAVVSLLLYFSIAERIQAYIAWSFGNFGGVTWSQMQVLAPTIGIGLILALLLTKVLN
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLLGEAYARSMGMDIQLARCGIVLSSSVLAGTITAFCGPIAFLGIAIPHLCRALFRTAD
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HRILLPACMWIGATIALLGDLIAQVPGYSIVLPLNAINALFGAPIVMWVVLQRYRGVFGL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKTLSAAIQSTRWPRPGLQPLVLLAMVGVTLCIFLLSLSLGSVSIPPEQVLSILLYQEA
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ERKSWVTIIYDFRLPKALTAALAGAALGVSGLQMQTLFRNPLADPFVLGISSGASLGVAI
CCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
VVLSVGAANTALLAVAGLLGNVSLVVAASLGAGMVMMIILTLAQRVRSSITLLILGLMIG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVTSAVVSLLLYFSIAERIQAYIAWSFGNFGGVTWSQMQVLAPTIGIGLILALLLTKVLN
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLLGEAYARSMGMDIQLARCGIVLSSSVLAGTITAFCGPIAFLGIAIPHLCRALFRTAD
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HRILLPACMWIGATIALLGDLIAQVPGYSIVLPLNAINALFGAPIVMWVVLQRYRGVFGL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA