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The map label for this gene is cseB [H]

Identifier: 222523334

GI number: 222523334

Start: 36960

End: 37901

Strand: Reverse

Name: cseB [H]

Synonym: Chy400_0035

Alternate gene names: 222523334

Gene position: 37901-36960 (Counterclockwise)

Preceding gene: 222523335

Following gene: 222523333

Centisome position: 0.72

GC content: 52.44

Gene sequence:

>942_bases
GTGTCTGAAGAAGTTCATCTGCCAACAGTTCTTTTCGCCGACGACGACCCCCATATTCGTACCTTGCTCAGTGATACATT
GACGCAAGCCGGTTTCGCTGTACTGGCTGCCGAAGATGGGTTGTCGTTGATTCGGATTGCCCAAGAGCAGTTACCAGACA
TCATTCTCGTTGATCTAATGCTCCCTGGGGTTGATGGTTACGAGGCAATTCGGCAACTGCGGAATGATACCCGCACTGCC
CATCTGCCTATCATTATTGTGACTGCACGTGCCAACCCATCTGATGTCGTCATCGGTTTTGATACCGGTGCCGATGATTA
CATCACCAAGCCGTTCAACGAAGCCGAACTTGTGGCACGTATTCGTTCGTTACTGCGGCGCATAACGAAGCGTCCGGTTC
GCAACCCATTGACCGGTTTGCCCGGCAATGTGCTCATCGGTGAGGAAATTCGCTACCGGCTTCAGCGCGGTGAACCATTT
ACTTTACTTTACACAGACATCAACGAATTCAAGGCGTTTAACGACAAGTATGGCTTTGCCCGTGGTGACCAGGTAATTCG
CCTGGTAGCCGAACTTTGCGAGCAGGCACAACAATTCTTTGCACCTCATGCTATCTTTGTCGGCCACATAGGCGGTGATG
ATTTTGTACTGCTCTGTCCGAGTACAGTTGCTGCTGACCTGGCGCGGTGGCTGGTTGATCAATTTGAACAGGCAGCATTA
TCGCTCTACGATGAGGAAGACCGCCAACGCGGCTACCTGGTCGGGTATGATCGAGCCGGTAATTTGCGCCATATTCCACT
GGCTACGATGGCTGTCGGTGGGGTTTCGAGCCGCCTGGATGCGACCGTTGATGAATTGTCACGGGAAGCAGCAGCCATGA
AACACGCGGCCAAGGTCTTTGGTACCAGTGCAGTCATCATTGATCATGTGCGCCTGCGCTAA

Upstream 100 bases:

>100_bases
GGACTGATTGCCACCACTCCCTTGATCAGTGCCCGTTATCCACTTGCTGAAGGTTTACAAGCGTTTGCCGCTGCTCCCGG
CCAACTTAAGGTTTTGCTCA

Downstream 100 bases:

>100_bases
TGGATGGTCTTGCCAGGGGTAGCACGGGCATCAGCCTGTGCTCCCTTATTCTCTGTAACTTGTCGGGCCATACATCTACA
CAGCCAATTTTCAGTTCAGA

Product: response regulator receiver modulated diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSEEVHLPTVLFADDDPHIRTLLSDTLTQAGFAVLAAEDGLSLIRIAQEQLPDIILVDLMLPGVDGYEAIRQLRNDTRTA
HLPIIIVTARANPSDVVIGFDTGADDYITKPFNEAELVARIRSLLRRITKRPVRNPLTGLPGNVLIGEEIRYRLQRGEPF
TLLYTDINEFKAFNDKYGFARGDQVIRLVAELCEQAQQFFAPHAIFVGHIGGDDFVLLCPSTVAADLARWLVDQFEQAAL
SLYDEEDRQRGYLVGYDRAGNLRHIPLATMAVGGVSSRLDATVDELSREAAAMKHAAKVFGTSAVIIDHVRLR

Sequences:

>Translated_313_residues
MSEEVHLPTVLFADDDPHIRTLLSDTLTQAGFAVLAAEDGLSLIRIAQEQLPDIILVDLMLPGVDGYEAIRQLRNDTRTA
HLPIIIVTARANPSDVVIGFDTGADDYITKPFNEAELVARIRSLLRRITKRPVRNPLTGLPGNVLIGEEIRYRLQRGEPF
TLLYTDINEFKAFNDKYGFARGDQVIRLVAELCEQAQQFFAPHAIFVGHIGGDDFVLLCPSTVAADLARWLVDQFEQAAL
SLYDEEDRQRGYLVGYDRAGNLRHIPLATMAVGGVSSRLDATVDELSREAAAMKHAAKVFGTSAVIIDHVRLR
>Mature_312_residues
SEEVHLPTVLFADDDPHIRTLLSDTLTQAGFAVLAAEDGLSLIRIAQEQLPDIILVDLMLPGVDGYEAIRQLRNDTRTAH
LPIIIVTARANPSDVVIGFDTGADDYITKPFNEAELVARIRSLLRRITKRPVRNPLTGLPGNVLIGEEIRYRLQRGEPFT
LLYTDINEFKAFNDKYGFARGDQVIRLVAELCEQAQQFFAPHAIFVGHIGGDDFVLLCPSTVAADLARWLVDQFEQAALS
LYDEEDRQRGYLVGYDRAGNLRHIPLATMAVGGVSSRLDATVDELSREAAAMKHAAKVFGTSAVIIDHVRLR

Specific function: Member of the two-component regulatory system CseB/CseC involved in the stability of the cell envelope. CseB activates transcription of RNA polymerase sigma-E factor, in response to changes in the cell envelope [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=44.1666666666667, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789809, Length=135, Percent_Identity=40.7407407407407, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790860, Length=129, Percent_Identity=39.5348837209302, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788394, Length=177, Percent_Identity=34.4632768361582, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=40.6779661016949, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=36.4406779661017, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786911, Length=131, Percent_Identity=38.9312977099237, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI2367329, Length=121, Percent_Identity=40.495867768595, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787229, Length=168, Percent_Identity=33.9285714285714, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790863, Length=123, Percent_Identity=35.7723577235772, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=40.6779661016949, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790299, Length=140, Percent_Identity=32.8571428571429, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789402, Length=157, Percent_Identity=35.031847133758, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790552, Length=122, Percent_Identity=39.344262295082, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=128, Percent_Identity=32.03125, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 34702; Mature: 34571

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEVHLPTVLFADDDPHIRTLLSDTLTQAGFAVLAAEDGLSLIRIAQEQLPDIILVDLM
CCCCEECCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCEEEEEHH
LPGVDGYEAIRQLRNDTRTAHLPIIIVTARANPSDVVIGFDTGADDYITKPFNEAELVAR
CCCCCHHHHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
IRSLLRRITKRPVRNPLTGLPGNVLIGEEIRYRLQRGEPFTLLYTDINEFKAFNDKYGFA
HHHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCCC
RGDQVIRLVAELCEQAQQFFAPHAIFVGHIGGDDFVLLCPSTVAADLARWLVDQFEQAAL
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHH
SLYDEEDRQRGYLVGYDRAGNLRHIPLATMAVGGVSSRLDATVDELSREAAAMKHAAKVF
HHHCCHHHCCCCEEEECCCCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GTSAVIIDHVRLR
CCCEEEEECEECC
>Mature Secondary Structure 
SEEVHLPTVLFADDDPHIRTLLSDTLTQAGFAVLAAEDGLSLIRIAQEQLPDIILVDLM
CCCEECCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCEEEEEHH
LPGVDGYEAIRQLRNDTRTAHLPIIIVTARANPSDVVIGFDTGADDYITKPFNEAELVAR
CCCCCHHHHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
IRSLLRRITKRPVRNPLTGLPGNVLIGEEIRYRLQRGEPFTLLYTDINEFKAFNDKYGFA
HHHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCCC
RGDQVIRLVAELCEQAQQFFAPHAIFVGHIGGDDFVLLCPSTVAADLARWLVDQFEQAAL
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHH
SLYDEEDRQRGYLVGYDRAGNLRHIPLATMAVGGVSSRLDATVDELSREAAAMKHAAKVF
HHHCCHHHCCCCEEEECCCCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GTSAVIIDHVRLR
CCCEEEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]