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The map label for this gene is hsdR [H]

Identifier: 222151726

GI number: 222151726

Start: 1600582

End: 1601970

Strand: Direct

Name: hsdR [H]

Synonym: MCCL_1479

Alternate gene names: 222151726

Gene position: 1600582-1601970 (Clockwise)

Preceding gene: 222151725

Following gene: 222151727

Centisome position: 76.13

GC content: 31.1

Gene sequence:

>1389_bases
GTGATCAAAATAGCTAAATTTGAATACGAAACGGTCAACGAATTGATAATGTATGCAAAAGAAGCAGAAGGTAAATATTT
GTATGAAATTGATAAGAAAGATATGTTGGAGAATACAAATGTAAAAGGCTCTGTGGGACATATTATCGAAGCTAGTTATT
TTGGTTATGAAATAAATTCAAATGCAGAACCTGACTTTGCAGATGTAGGAATAGAACTAAAAGCTACTGGTATCCAAAAG
ATGAAAAAAGGAGACCTAAAAGCCAAAGAGCGACTCGTATTAAATATAATCAATTACTGTGACGAAGCTACAGTTGAATT
TGAGTCATCAAGCTTTTGGAAGAAAAATAAACATTTACTTCTCTTCTTCTATGAATATAAAAAAGATAAAAACAACAAAA
TGGATCGCAGAAACGCTCAAATAATTAAAGTTGAAGACTTCCAATTTCCAGAAGAAGACTTAAAAACAATAAAACAAGAT
TGGAATATAATACATAACAAAATCATCAATGGTGAAGCCCACCTACTTTCTGAAGGTGACACATTAATACTTGGTGCATG
TACCAAAGGTTCCACTGCAGCAAAATCTTTAAGAAAACAGCCTAATAGTGATATTTTGGCTAAGCAGCGAGCATATTCTA
TTAAGCAAGGATACATGTCAAATCTTGTTCGAAAGTTAATTACAAAAGAGCAATTTGAAGCAATTACGACTGCAAAAGAG
CTAAATGAAAAGTCTATCGATCAGATATTACATAATAAATTTAAGAATTACTATGGTAAATCTGATGTTGAAATAGCTGA
ACAATTAAATATCACTCTTAGTGATGGGAAAAATCGTATCGCACATCTGATAAGTAATATGTTAGGTATTAAGAAGAATG
ATTTAAGTAAAATCGAGGAATTTGAAAAGTATAGCATTAAATTTAAAACGATCACTTTAAATAATGAAGATAAATTGAAA
GAACACATGTCTTTTGAGAACATTGACTTTGATGAGTATGCTACTTCTGAGTGGGATGATAGCCATTTAAAAACGATGTT
CGAATCAACAAAATGGTTATTTGTTGTATTTAAAGAAGATGATAAACATAATAAAATATTTCTTGGGTACAAGTTATGGA
ACATGCCAATGACTGATATCGAAGGACCATTACAAGAGTTTTTCATAAAAACACAACGCATTCTTAACGAAGGTGTTATA
CTGTCACAGACTTCAAGAGGTATACGTAATAACCTGCCTGGCGCAAAAGATAATCCAATTTGTCATATCAGACCAAAAGC
TAGAAATGCTGAAGATAAAGTTAAACTTCCAGATGGACAATGTATTACTAAACAGTGTTTTTGGTTGAATAAGGGGTATA
TCAAAAATATTTTACAAGGAGTAATATAA

Upstream 100 bases:

>100_bases
AATTCAGGCGAAAAATATAATGAACGTCCTATCAACTTAGTATTTCCAAAACACGAACTCATTAAGATTTCTAAATTTCA
CACAATACATAAAATAGAAG

Downstream 100 bases:

>100_bases
TGAAAAGGCTTATATTAGGAGAATTATATAGTAGAGAAGACGTTAGTAAAATATTTAATAGTCAATCTAAATATACCAGA
GGCTCAGGTGTATGGGGATT

Product: type II restriction enzyme

Products: NA

Alternate protein names: R.Sau3AI; Endonuclease Sau3AI; Type II restriction enzyme Sau3AI [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MIKIAKFEYETVNELIMYAKEAEGKYLYEIDKKDMLENTNVKGSVGHIIEASYFGYEINSNAEPDFADVGIELKATGIQK
MKKGDLKAKERLVLNIINYCDEATVEFESSSFWKKNKHLLLFFYEYKKDKNNKMDRRNAQIIKVEDFQFPEEDLKTIKQD
WNIIHNKIINGEAHLLSEGDTLILGACTKGSTAAKSLRKQPNSDILAKQRAYSIKQGYMSNLVRKLITKEQFEAITTAKE
LNEKSIDQILHNKFKNYYGKSDVEIAEQLNITLSDGKNRIAHLISNMLGIKKNDLSKIEEFEKYSIKFKTITLNNEDKLK
EHMSFENIDFDEYATSEWDDSHLKTMFESTKWLFVVFKEDDKHNKIFLGYKLWNMPMTDIEGPLQEFFIKTQRILNEGVI
LSQTSRGIRNNLPGAKDNPICHIRPKARNAEDKVKLPDGQCITKQCFWLNKGYIKNILQGVI

Sequences:

>Translated_462_residues
MIKIAKFEYETVNELIMYAKEAEGKYLYEIDKKDMLENTNVKGSVGHIIEASYFGYEINSNAEPDFADVGIELKATGIQK
MKKGDLKAKERLVLNIINYCDEATVEFESSSFWKKNKHLLLFFYEYKKDKNNKMDRRNAQIIKVEDFQFPEEDLKTIKQD
WNIIHNKIINGEAHLLSEGDTLILGACTKGSTAAKSLRKQPNSDILAKQRAYSIKQGYMSNLVRKLITKEQFEAITTAKE
LNEKSIDQILHNKFKNYYGKSDVEIAEQLNITLSDGKNRIAHLISNMLGIKKNDLSKIEEFEKYSIKFKTITLNNEDKLK
EHMSFENIDFDEYATSEWDDSHLKTMFESTKWLFVVFKEDDKHNKIFLGYKLWNMPMTDIEGPLQEFFIKTQRILNEGVI
LSQTSRGIRNNLPGAKDNPICHIRPKARNAEDKVKLPDGQCITKQCFWLNKGYIKNILQGVI
>Mature_462_residues
MIKIAKFEYETVNELIMYAKEAEGKYLYEIDKKDMLENTNVKGSVGHIIEASYFGYEINSNAEPDFADVGIELKATGIQK
MKKGDLKAKERLVLNIINYCDEATVEFESSSFWKKNKHLLLFFYEYKKDKNNKMDRRNAQIIKVEDFQFPEEDLKTIKQD
WNIIHNKIINGEAHLLSEGDTLILGACTKGSTAAKSLRKQPNSDILAKQRAYSIKQGYMSNLVRKLITKEQFEAITTAKE
LNEKSIDQILHNKFKNYYGKSDVEIAEQLNITLSDGKNRIAHLISNMLGIKKNDLSKIEEFEKYSIKFKTITLNNEDKLK
EHMSFENIDFDEYATSEWDDSHLKTMFESTKWLFVVFKEDDKHNKIFLGYKLWNMPMTDIEGPLQEFFIKTQRILNEGVI
LSQTSRGIRNNLPGAKDNPICHIRPKARNAEDKVKLPDGQCITKQCFWLNKGYIKNILQGVI

Specific function: Recognizes the double-stranded sequence GATC and cleaves before G-1 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011337
- InterPro:   IPR011335 [H]

Pfam domain/function: PF02976 MutH [H]

EC number: =3.1.21.4 [H]

Molecular weight: Translated: 53586; Mature: 53586

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIAKFEYETVNELIMYAKEAEGKYLYEIDKKDMLENTNVKGSVGHIIEASYFGYEINS
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCCCCEEEEEEECEEECC
NAEPDFADVGIELKATGIQKMKKGDLKAKERLVLNIINYCDEATVEFESSSFWKKNKHLL
CCCCCHHHCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEE
LFFYEYKKDKNNKMDRRNAQIIKVEDFQFPEEDLKTIKQDWNIIHNKIINGEAHLLSEGD
EEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCEEEECCCC
TLILGACTKGSTAAKSLRKQPNSDILAKQRAYSIKQGYMSNLVRKLITKEQFEAITTAKE
EEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNEKSIDQILHNKFKNYYGKSDVEIAEQLNITLSDGKNRIAHLISNMLGIKKNDLSKIEE
HCHHHHHHHHHHHHHHHCCCCCCEEHHHCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHH
FEKYSIKFKTITLNNEDKLKEHMSFENIDFDEYATSEWDDSHLKTMFESTKWLFVVFKED
HHHHEEEEEEEEECCHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHCCCCEEEEEEECC
DKHNKIFLGYKLWNMPMTDIEGPLQEFFIKTQRILNEGVILSQTSRGIRNNLPGAKDNPI
CCCCEEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHCCCCCCCCCE
CHIRPKARNAEDKVKLPDGQCITKQCFWLNKGYIKNILQGVI
EEECCCCCCCCCCEECCCCCCHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MIKIAKFEYETVNELIMYAKEAEGKYLYEIDKKDMLENTNVKGSVGHIIEASYFGYEINS
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCCCCEEEEEEECEEECC
NAEPDFADVGIELKATGIQKMKKGDLKAKERLVLNIINYCDEATVEFESSSFWKKNKHLL
CCCCCHHHCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEE
LFFYEYKKDKNNKMDRRNAQIIKVEDFQFPEEDLKTIKQDWNIIHNKIINGEAHLLSEGD
EEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCEEEECCCC
TLILGACTKGSTAAKSLRKQPNSDILAKQRAYSIKQGYMSNLVRKLITKEQFEAITTAKE
EEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNEKSIDQILHNKFKNYYGKSDVEIAEQLNITLSDGKNRIAHLISNMLGIKKNDLSKIEE
HCHHHHHHHHHHHHHHHCCCCCCEEHHHCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHH
FEKYSIKFKTITLNNEDKLKEHMSFENIDFDEYATSEWDDSHLKTMFESTKWLFVVFKED
HHHHEEEEEEEEECCHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHCCCCEEEEEEECC
DKHNKIFLGYKLWNMPMTDIEGPLQEFFIKTQRILNEGVILSQTSRGIRNNLPGAKDNPI
CCCCEEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHCCCCCCCCCE
CHIRPKARNAEDKVKLPDGQCITKQCFWLNKGYIKNILQGVI
EEECCCCCCCCCCEECCCCCCHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2227451 [H]