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The map label for this gene is rnhC

Identifier: 222151572

GI number: 222151572

Start: 1434692

End: 1435633

Strand: Direct

Name: rnhC

Synonym: MCCL_1325

Alternate gene names: 222151572

Gene position: 1434692-1435633 (Clockwise)

Preceding gene: 222151559

Following gene: 222151575

Centisome position: 68.24

GC content: 36.52

Gene sequence:

>942_bases
ATGACCAATAAAGTTTACCTATTAACTGATGAACAATCAAAAAAGATAGAACATGTATTACCTACATCTGATACGACGAA
TCTTCCACAAGGTACGAAATATCGAACAAAAATATCCGGACACACAGTCACATTATACAACTCTAATAAACTGATGATCC
AAGGTGCAGATAGTGAAGTAATCGGTGAACAAATTCTTTCTAAAGCTGGTATTCAACTCACTCAGCAACTTCCAGATAGT
AATTCTACCTCTAAGCATAACGTATCCATTGAAAGTATCCAGTATGATAACTACAACTGTATCGGTAGCGATGAAGCAGG
TTCTGGGGACTACTTCGGACCGATGACCGTTGTCGCGAGCTATGTATCAAAGAAAAATGCTGAAATTCTGAAAGTGCTTG
GTGTCATGGATTCTAAGAATCTCAAGGACAGACAAATTATAGAACTTGCAGAACAAATCATCCCGATAATTCCACATTCA
CTGCTCGTCCTAGATAACATCAAATATAATGAACGTAAACAGATGGGCTGGTCACAAGTTAAGATGAAAGCGGTGCTGCA
TAATGAAGCGATTAAAAACGTTCTGAACAAAATAGAAGAACCTGTTGATTACATTGTAATCGACCAGTTTGCAGTTCAAG
GTGTATATGAAAATTATGCACTCGGTGCAATACCTGAGCGAAATAAAACTAAATTCGAAACGAAAGGTGAATCTAAAGCG
ATTGCCATCGCCGCAAGCTCCATTATTGCAAGATATGCGTTTGTAAAACATTTCGAACAAATAATTAAAGAGACCGGCAT
CTCAATCACAAAAGGAGCAGGCGCTAAAGTAGATGTCGAAGCTGCAAAAATTATTAAACTTAGAGGCATTGATTATTTAG
ATACGATAACGAAAAAAGACTTTAAAAATAGAGAAAAAGCATTGAAGCTCATAAAAAAATAA

Upstream 100 bases:

>100_bases
TATCAACACTCCGACATCGTTATTTATTTTAGTTTATGTTAACATTTTTATATGATAATTAACAATAAAAACATACTAAT
ATGTTAGAAAGCAGGCTGAA

Downstream 100 bases:

>100_bases
GCTGACGATTGTCAGCCTATTTTTTATCCTCTAAGTTTAGCGCCAATTGACTCTAATCTTTCAATAACCGCATCATATAT
CGGTTTAATTTCTTCATCTG

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTNKVYLLTDEQSKKIEHVLPTSDTTNLPQGTKYRTKISGHTVTLYNSNKLMIQGADSEVIGEQILSKAGIQLTQQLPDS
NSTSKHNVSIESIQYDNYNCIGSDEAGSGDYFGPMTVVASYVSKKNAEILKVLGVMDSKNLKDRQIIELAEQIIPIIPHS
LLVLDNIKYNERKQMGWSQVKMKAVLHNEAIKNVLNKIEEPVDYIVIDQFAVQGVYENYALGAIPERNKTKFETKGESKA
IAIAASSIIARYAFVKHFEQIIKETGISITKGAGAKVDVEAAKIIKLRGIDYLDTITKKDFKNREKALKLIKK

Sequences:

>Translated_313_residues
MTNKVYLLTDEQSKKIEHVLPTSDTTNLPQGTKYRTKISGHTVTLYNSNKLMIQGADSEVIGEQILSKAGIQLTQQLPDS
NSTSKHNVSIESIQYDNYNCIGSDEAGSGDYFGPMTVVASYVSKKNAEILKVLGVMDSKNLKDRQIIELAEQIIPIIPHS
LLVLDNIKYNERKQMGWSQVKMKAVLHNEAIKNVLNKIEEPVDYIVIDQFAVQGVYENYALGAIPERNKTKFETKGESKA
IAIAASSIIARYAFVKHFEQIIKETGISITKGAGAKVDVEAAKIIKLRGIDYLDTITKKDFKNREKALKLIKK
>Mature_312_residues
TNKVYLLTDEQSKKIEHVLPTSDTTNLPQGTKYRTKISGHTVTLYNSNKLMIQGADSEVIGEQILSKAGIQLTQQLPDSN
STSKHNVSIESIQYDNYNCIGSDEAGSGDYFGPMTVVASYVSKKNAEILKVLGVMDSKNLKDRQIIELAEQIIPIIPHSL
LVLDNIKYNERKQMGWSQVKMKAVLHNEAIKNVLNKIEEPVDYIVIDQFAVQGVYENYALGAIPERNKTKFETKGESKAI
AIAASSIIARYAFVKHFEQIIKETGISITKGAGAKVDVEAAKIIKLRGIDYLDTITKKDFKNREKALKLIKK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_MACCJ (B9E764)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560728.1
- GeneID:   7389327
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_1325
- OMA:   ASIIARY
- ProtClustDB:   PRK00996
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 34907; Mature: 34775

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKVYLLTDEQSKKIEHVLPTSDTTNLPQGTKYRTKISGHTVTLYNSNKLMIQGADSEV
CCCEEEEEECCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEECCEEEEECCCHHH
IGEQILSKAGIQLTQQLPDSNSTSKHNVSIESIQYDNYNCIGSDEAGSGDYFGPMTVVAS
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCEEECCCCCCCCCCCCHHHHHHHH
YVSKKNAEILKVLGVMDSKNLKDRQIIELAEQIIPIIPHSLLVLDNIKYNERKQMGWSQV
HHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCHHHH
KMKAVLHNEAIKNVLNKIEEPVDYIVIDQFAVQGVYENYALGAIPERNKTKFETKGESKA
HHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCE
IAIAASSIIARYAFVKHFEQIIKETGISITKGAGAKVDVEAAKIIKLRGIDYLDTITKKD
EEHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHEEEECCCHHHHHHHHHH
FKNREKALKLIKK
HHHHHHHHHHHCC
>Mature Secondary Structure 
TNKVYLLTDEQSKKIEHVLPTSDTTNLPQGTKYRTKISGHTVTLYNSNKLMIQGADSEV
CCEEEEEECCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEECCEEEEECCCHHH
IGEQILSKAGIQLTQQLPDSNSTSKHNVSIESIQYDNYNCIGSDEAGSGDYFGPMTVVAS
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCEEECCCCCCCCCCCCHHHHHHHH
YVSKKNAEILKVLGVMDSKNLKDRQIIELAEQIIPIIPHSLLVLDNIKYNERKQMGWSQV
HHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCHHHH
KMKAVLHNEAIKNVLNKIEEPVDYIVIDQFAVQGVYENYALGAIPERNKTKFETKGESKA
HHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCE
IAIAASSIIARYAFVKHFEQIIKETGISITKGAGAKVDVEAAKIIKLRGIDYLDTITKKD
EEHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHEEEECCCHHHHHHHHHH
FKNREKALKLIKK
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA