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The map label for this gene is alr2 [H]

Identifier: 222151301

GI number: 222151301

Start: 1162557

End: 1163639

Strand: Direct

Name: alr2 [H]

Synonym: MCCL_1054

Alternate gene names: 222151301

Gene position: 1162557-1163639 (Clockwise)

Preceding gene: 222151300

Following gene: 222151302

Centisome position: 55.3

GC content: 35.73

Gene sequence:

>1083_bases
ATGACTGCGCGATGGACTGTAGATCGTACTAAGTTTATAGAAAATGTGAAATCCGTGATAGATAATACTCCTGTAATGGC
CGTCGTAAAGAACAATGCCTATCATTATGGACTGGAATTTGCAATAGATGCATTTCTACAAGCTGGTATTACAACTTTTA
GTACAACCAATTTAAATGAAGCAATTCTCATAAGAAAAATAGCACCAGAAGCTACTATATTTTTGATGAATCCAGTTACT
CGTTTCAATGACTTAAGACAATATAATATTCAAATGACGCTACCTTCTTTAGCTTTCTATCATAGGTATCAGTCTGAATT
AGACGGGATATCAGTACATCTCGAATATGAAAATCTTCTCCATCGCTCAGGGTTTAAAACATTTGAGGAAATGAAAACTG
TAATTGATGACAATAATCAGTTACCTGTTCATTTACAGATGAATATTAACGGGATATGGACCCATTTCGGCTATGCCGAT
GAATTTGATGTTATAGAATACGAAATTGAAAAAGAATCCTGGTTAAAAGGGCTGAAATGGATTTCTAGGTATCATACTTT
TGAGATGATCCATAGTCAAAATAGCGCAAGTTTTATACGAGATAAGATATTTGATGAACACACACATGTCAGAATTGGCA
TCATCCTGTATGGGAGCAGACCCTATGCATCATTAGATGAATCCGTTACGCACCAATCATTAACTGTTAGTGCAAATGTA
ATTCAAGTAAGAAATATATCAAAGGGAGAATCTGCAGGATACAGCTTCGCCTTTACAGCAGAAAAAGAAACGAAGCTCGC
TGTAGTAGACATCGGTTATGGAGATGGCATATTGAGGACGAGAAGTAAGCATGACTGCATTATCAAGGGTAGACGTTACC
CTATTCGTGCTTTGATGATGAGTCATATGTTTGTAGAAGTAGATAATACAGTAGAAGCTGAAGATGAAGTAATATTGTAT
AGTGATGAGATTCGTATCGATGAATTTACCTTTAAGGGCATCGGAGCAAATTCAGAACAACTCAGCGCCTTGAACCATCA
ATCACTAATAAAGGAGTATATCAATGACATTAACATATATTAA

Upstream 100 bases:

>100_bases
TTACAGGGCTTCATACGTCGACGTTCAACTTTGATGAATCCGCATTGATATATGGGATTGACGTTCTGGAAGCAATTTTT
AACAGATTTGAGGGGTTACA

Downstream 100 bases:

>100_bases
TAATCAACTTACTATTAACGGCCATAATATTCGACAAATCGCTGAACAATATGGTACACCATTATTTATTTACGATGAGG
ATGAGATACGCAATCAGTGC

Product: alanine racemase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTARWTVDRTKFIENVKSVIDNTPVMAVVKNNAYHYGLEFAIDAFLQAGITTFSTTNLNEAILIRKIAPEATIFLMNPVT
RFNDLRQYNIQMTLPSLAFYHRYQSELDGISVHLEYENLLHRSGFKTFEEMKTVIDDNNQLPVHLQMNINGIWTHFGYAD
EFDVIEYEIEKESWLKGLKWISRYHTFEMIHSQNSASFIRDKIFDEHTHVRIGIILYGSRPYASLDESVTHQSLTVSANV
IQVRNISKGESAGYSFAFTAEKETKLAVVDIGYGDGILRTRSKHDCIIKGRRYPIRALMMSHMFVEVDNTVEAEDEVILY
SDEIRIDEFTFKGIGANSEQLSALNHQSLIKEYINDINIY

Sequences:

>Translated_360_residues
MTARWTVDRTKFIENVKSVIDNTPVMAVVKNNAYHYGLEFAIDAFLQAGITTFSTTNLNEAILIRKIAPEATIFLMNPVT
RFNDLRQYNIQMTLPSLAFYHRYQSELDGISVHLEYENLLHRSGFKTFEEMKTVIDDNNQLPVHLQMNINGIWTHFGYAD
EFDVIEYEIEKESWLKGLKWISRYHTFEMIHSQNSASFIRDKIFDEHTHVRIGIILYGSRPYASLDESVTHQSLTVSANV
IQVRNISKGESAGYSFAFTAEKETKLAVVDIGYGDGILRTRSKHDCIIKGRRYPIRALMMSHMFVEVDNTVEAEDEVILY
SDEIRIDEFTFKGIGANSEQLSALNHQSLIKEYINDINIY
>Mature_359_residues
TARWTVDRTKFIENVKSVIDNTPVMAVVKNNAYHYGLEFAIDAFLQAGITTFSTTNLNEAILIRKIAPEATIFLMNPVTR
FNDLRQYNIQMTLPSLAFYHRYQSELDGISVHLEYENLLHRSGFKTFEEMKTVIDDNNQLPVHLQMNINGIWTHFGYADE
FDVIEYEIEKESWLKGLKWISRYHTFEMIHSQNSASFIRDKIFDEHTHVRIGIILYGSRPYASLDESVTHQSLTVSANVI
QVRNISKGESAGYSFAFTAEKETKLAVVDIGYGDGILRTRSKHDCIIKGRRYPIRALMMSHMFVEVDNTVEAEDEVILYS
DEIRIDEFTFKGIGANSEQLSALNHQSLIKEYINDINIY

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=346, Percent_Identity=25.4335260115607, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787439, Length=348, Percent_Identity=23.8505747126437, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41522; Mature: 41390

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARWTVDRTKFIENVKSVIDNTPVMAVVKNNAYHYGLEFAIDAFLQAGITTFSTTNLNE
CCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHHCCCEEEECCCCC
AILIRKIAPEATIFLMNPVTRFNDLRQYNIQMTLPSLAFYHRYQSELDGISVHLEYENLL
EEEEEEECCCEEEEEECCHHHHCCHHEEEEEEECHHHHHHHHHHHCCCCEEEEEEHHHHH
HRSGFKTFEEMKTVIDDNNQLPVHLQMNINGIWTHFGYADEFDVIEYEIEKESWLKGLKW
HHCCCHHHHHHHHHHCCCCCEEEEEEEECCEEEEECCCCCCCCEEEEEECHHHHHHHHHH
ISRYHTFEMIHSQNSASFIRDKIFDEHTHVRIGIILYGSRPYASLDESVTHQSLTVSANV
HHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHCCCEEEEEEEE
IQVRNISKGESAGYSFAFTAEKETKLAVVDIGYGDGILRTRSKHDCIIKGRRYPIRALMM
EEEECCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEECCCCCCEEEECCCCHHHHHHH
SHMFVEVDNTVEAEDEVILYSDEIRIDEFTFKGIGANSEQLSALNHQSLIKEYINDINIY
HHHEEEECCCCCCCCCEEEEECCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TARWTVDRTKFIENVKSVIDNTPVMAVVKNNAYHYGLEFAIDAFLQAGITTFSTTNLNE
CCEEECHHHHHHHHHHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHHCCCEEEECCCCC
AILIRKIAPEATIFLMNPVTRFNDLRQYNIQMTLPSLAFYHRYQSELDGISVHLEYENLL
EEEEEEECCCEEEEEECCHHHHCCHHEEEEEEECHHHHHHHHHHHCCCCEEEEEEHHHHH
HRSGFKTFEEMKTVIDDNNQLPVHLQMNINGIWTHFGYADEFDVIEYEIEKESWLKGLKW
HHCCCHHHHHHHHHHCCCCCEEEEEEEECCEEEEECCCCCCCCEEEEEECHHHHHHHHHH
ISRYHTFEMIHSQNSASFIRDKIFDEHTHVRIGIILYGSRPYASLDESVTHQSLTVSANV
HHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHCCCEEEEEEEE
IQVRNISKGESAGYSFAFTAEKETKLAVVDIGYGDGILRTRSKHDCIIKGRRYPIRALMM
EEEECCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEECCCCCCEEEECCCCHHHHHHH
SHMFVEVDNTVEAEDEVILYSDEIRIDEFTFKGIGANSEQLSALNHQSLIKEYINDINIY
HHHEEEECCCCCCCCCEEEEECCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11447207 [H]