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The map label for this gene is uvrX [H]

Identifier: 222151280

GI number: 222151280

Start: 1138539

End: 1139852

Strand: Direct

Name: uvrX [H]

Synonym: MCCL_1033

Alternate gene names: 222151280

Gene position: 1138539-1139852 (Clockwise)

Preceding gene: 222151279

Following gene: 222151281

Centisome position: 54.16

GC content: 39.35

Gene sequence:

>1314_bases
ATGTTCTGGTATGATAAATATATCATCAAAGATTATAAGAGGGTGCTTAATATGTATGATTACAGTCTATGCGAGAAAAG
GAATGTACTCTGTATTGACCAGAAGAGTTTCTTTGCGAGTGTTTCTTGCATCATGATAGGACTTGATCCTATGACAACAA
AGCTCGCTGTTGTCGCTGATACGAAACGACAGGGGTCTGTTGTACTTGCTGCTACACCACCTCTAAAGATGCTGGGGATA
AAGACCGGTTCACGTTTATTTGAAATACCTCATCGTTCTGATATTTATATTATCAATCCTTCGATGAACACTTACCTGAA
AGTTGCCAGTCAAATTGCTGAGATTTCACTGCAATATGTTGCACCGGAGGATTACCATCAATATAGTATCGATGAATTTT
TTATGGATGTTACAAAGAGTTATAAACTATACGCAGAAAGTCCGTATGCGCTTGCCTTAAAGATTAAACAGGAGATTTAT
GATAAGACGCAAATTCAGTGTGCCGTGGGAATAGGGGATAATGTCTTACTCAGCAAGATTGCACTGGATATGGAAGCAAA
GACACAACCGGATGGTATTGCTGAGTGGCATTACGAAGATGTACCGGTAAAGATGTGGTCGATTGAGCCGTTAAGTAAGT
TCTGGGGAATTAATCGTCGCACCGAGAAGAAACTCAATCAAAAGGGGATATTCACGATTGGGCAGCTTGCTAATTATCCG
CATCATTATTTAAAGCGCGATTTCGGTATTATCGGAGTAGACCTGCATTTACATGCGAATGGCATCGACTCAAGTTTAAT
CCGAGAGAAACATCATATTTATAAACCCTCTATTAATAAAAGTCAGATTTTAATGCGTGATTACCGTTTCGATGAACTAC
GAGCTGTCGTGTTAGAACATGTTGAAGAAGTAACATTCAGACTACGTGCCGACAATATGATTGCACGTACGATTTCTTTT
ACAGTTGGTTATAGTGATGAAGGGAAAGTGAATAAAAGTTATACATTATCTGAAGGTACGAATTTAACCGCTGATATCTT
TCAGTTTGTATGGGGATTTATGATGCAGTTGTGTGATAAGAAACGGATGTATCGTACAGTAAATATTTCACTTACGAACT
TTATTCGTGAGGAAGATCATCAGTTATCACTCTTTGTCGATGAGTTTGAACGTGAAAAACAAGAGAGACTGGAAAAGACG
GTAGACCAGCTAAAGATACGTTTCGGGAAGAATAGCGTCTTGCGTGCAGTATCGTATACAGAGCAAGGCACAGCGATGAA
GCGCAATGGTCTTATCGCTGGTCATAAGGCATAG

Upstream 100 bases:

>100_bases
GCTAATATGGAGTGGCAGCCCATATTAGCCGTTTATTTATTTCTGTTTTAATATCTTGAAAAATAAGAACATACGTTCTA
TTTTTATTTAAATAGAACGT

Downstream 100 bases:

>100_bases
TCAGATATCATAAATATAAACAAAAGATATAATCAATCGTAAAACCAACCTGTATTTCTAGAATTATTTATCTATCAAAC
GTATAATAGACATAAATTGT

Product: DNA-damage repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MFWYDKYIIKDYKRVLNMYDYSLCEKRNVLCIDQKSFFASVSCIMIGLDPMTTKLAVVADTKRQGSVVLAATPPLKMLGI
KTGSRLFEIPHRSDIYIINPSMNTYLKVASQIAEISLQYVAPEDYHQYSIDEFFMDVTKSYKLYAESPYALALKIKQEIY
DKTQIQCAVGIGDNVLLSKIALDMEAKTQPDGIAEWHYEDVPVKMWSIEPLSKFWGINRRTEKKLNQKGIFTIGQLANYP
HHYLKRDFGIIGVDLHLHANGIDSSLIREKHHIYKPSINKSQILMRDYRFDELRAVVLEHVEEVTFRLRADNMIARTISF
TVGYSDEGKVNKSYTLSEGTNLTADIFQFVWGFMMQLCDKKRMYRTVNISLTNFIREEDHQLSLFVDEFEREKQERLEKT
VDQLKIRFGKNSVLRAVSYTEQGTAMKRNGLIAGHKA

Sequences:

>Translated_437_residues
MFWYDKYIIKDYKRVLNMYDYSLCEKRNVLCIDQKSFFASVSCIMIGLDPMTTKLAVVADTKRQGSVVLAATPPLKMLGI
KTGSRLFEIPHRSDIYIINPSMNTYLKVASQIAEISLQYVAPEDYHQYSIDEFFMDVTKSYKLYAESPYALALKIKQEIY
DKTQIQCAVGIGDNVLLSKIALDMEAKTQPDGIAEWHYEDVPVKMWSIEPLSKFWGINRRTEKKLNQKGIFTIGQLANYP
HHYLKRDFGIIGVDLHLHANGIDSSLIREKHHIYKPSINKSQILMRDYRFDELRAVVLEHVEEVTFRLRADNMIARTISF
TVGYSDEGKVNKSYTLSEGTNLTADIFQFVWGFMMQLCDKKRMYRTVNISLTNFIREEDHQLSLFVDEFEREKQERLEKT
VDQLKIRFGKNSVLRAVSYTEQGTAMKRNGLIAGHKA
>Mature_437_residues
MFWYDKYIIKDYKRVLNMYDYSLCEKRNVLCIDQKSFFASVSCIMIGLDPMTTKLAVVADTKRQGSVVLAATPPLKMLGI
KTGSRLFEIPHRSDIYIINPSMNTYLKVASQIAEISLQYVAPEDYHQYSIDEFFMDVTKSYKLYAESPYALALKIKQEIY
DKTQIQCAVGIGDNVLLSKIALDMEAKTQPDGIAEWHYEDVPVKMWSIEPLSKFWGINRRTEKKLNQKGIFTIGQLANYP
HHYLKRDFGIIGVDLHLHANGIDSSLIREKHHIYKPSINKSQILMRDYRFDELRAVVLEHVEEVTFRLRADNMIARTISF
TVGYSDEGKVNKSYTLSEGTNLTADIFQFVWGFMMQLCDKKRMYRTVNISLTNFIREEDHQLSLFVDEFEREKQERLEKT
VDQLKIRFGKNSVLRAVSYTEQGTAMKRNGLIAGHKA

Specific function: Involved In Uv Protection And Mutation. Essential For Induced (Or Sos) Mutagenesis. May Modify The DNA Replication Machinery To Allow Bypass Synthesis Across A Damaged Template. [C]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=412, Percent_Identity=22.8155339805825, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786425, Length=299, Percent_Identity=24.4147157190635, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 50641; Mature: 50641

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWYDKYIIKDYKRVLNMYDYSLCEKRNVLCIDQKSFFASVSCIMIGLDPMTTKLAVVAD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHEEEEEEEECCCCCEEEEEEEE
TKRQGSVVLAATPPLKMLGIKTGSRLFEIPHRSDIYIINPSMNTYLKVASQIAEISLQYV
CCCCCCEEEEECCCEEEEEECCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHEEEEE
APEDYHQYSIDEFFMDVTKSYKLYAESPYALALKIKQEIYDKTQIQCAVGIGDNVLLSKI
CCCCCCCCCHHHHHHHHHHCCEEEECCCEEEEEEEHHHHCCCCEEEEEECCCCHHHHHHH
ALDMEAKTQPDGIAEWHYEDVPVKMWSIEPLSKFWGINRRTEKKLNQKGIFTIGQLANYP
HHCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHCCCCCHHHHHHCCCCCEEEHHHCCCC
HHYLKRDFGIIGVDLHLHANGIDSSLIREKHHIYKPSINKSQILMRDYRFDELRAVVLEH
HHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHH
VEEVTFRLRADNMIARTISFTVGYSDEGKVNKSYTLSEGTNLTADIFQFVWGFMMQLCDK
HHHHHHHEECCCEEEEEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCH
KRMYRTVNISLTNFIREEDHQLSLFVDEFEREKQERLEKTVDQLKIRFGKNSVLRAVSYT
HHHEEEEEEEHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHEEEC
EQGTAMKRNGLIAGHKA
CCCCCCCCCCEEECCCC
>Mature Secondary Structure
MFWYDKYIIKDYKRVLNMYDYSLCEKRNVLCIDQKSFFASVSCIMIGLDPMTTKLAVVAD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHEEEEEEEECCCCCEEEEEEEE
TKRQGSVVLAATPPLKMLGIKTGSRLFEIPHRSDIYIINPSMNTYLKVASQIAEISLQYV
CCCCCCEEEEECCCEEEEEECCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHEEEEE
APEDYHQYSIDEFFMDVTKSYKLYAESPYALALKIKQEIYDKTQIQCAVGIGDNVLLSKI
CCCCCCCCCHHHHHHHHHHCCEEEECCCEEEEEEEHHHHCCCCEEEEEECCCCHHHHHHH
ALDMEAKTQPDGIAEWHYEDVPVKMWSIEPLSKFWGINRRTEKKLNQKGIFTIGQLANYP
HHCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHCCCCCHHHHHHCCCCCEEEHHHCCCC
HHYLKRDFGIIGVDLHLHANGIDSSLIREKHHIYKPSINKSQILMRDYRFDELRAVVLEH
HHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHH
VEEVTFRLRADNMIARTISFTVGYSDEGKVNKSYTLSEGTNLTADIFQFVWGFMMQLCDK
HHHHHHHEECCCEEEEEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCH
KRMYRTVNISLTNFIREEDHQLSLFVDEFEREKQERLEKTVDQLKIRFGKNSVLRAVSYT
HHHEEEEEEEHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHEEEC
EQGTAMKRNGLIAGHKA
CCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]