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The map label for this gene is glcB [H]

Identifier: 222151263

GI number: 222151263

Start: 1122259

End: 1124340

Strand: Direct

Name: glcB [H]

Synonym: MCCL_1016

Alternate gene names: 222151263

Gene position: 1122259-1124340 (Clockwise)

Preceding gene: 222151262

Following gene: 222151264

Centisome position: 53.38

GC content: 38.38

Gene sequence:

>2082_bases
ATGTGGAAAACGTTTTTCGGTCAATTACAACGTATCGGTAAAGCATTGATGCTTCCGGTGGCATTATTACCAGCTGCAGG
AATACTGCTTGCATTTGGTAACGCAATGCATAATGAACAACTTGTTCAGATAGCACCATGGTTAGATAATGGATTCTTTG
TAATGCTATCAGGTATTATGGAAAGTGCTGGACAGGTTATTTTTGATAATTTACCTTTATTATTTGCAATTGGTACAGCG
CTAGGGTTAGCAGGTGGTGATGGTGTTGCTGGACTTGCTGCATTAGTAGGTTATTTAATTATGAATGCTACTATCGGTAA
GTTTATGGGAATTACTATCGATGATATTTTCAGCTATGCTGAAGGGGCGAAGACACTAGGGCAATCCGCTAAAGAACCGG
CAAACGCTTTAATTTTAGGCATACCAACCCTTCAAACAGGTGTATTTGGCGGAATTATTATGGGTGCGGTTGCTGCATGG
TGCTATAATAAGTTTTACAATATTAATATGCCTGCTTTCTTAGGGTTTTTCGCTGGTAAACGATTCGTGCCAATCATTAC
TTCAGTGATGGCAATCATTGTGGGTGCGATTCTAGCGATTATCTGGCCACCAATTCAGGGCGGTTTAAATACATTGTCTG
AATTCTTATTGAATAAAAACTTAGTATTAACGACCTTTATTTTTGGTGTCATTGAACGTGCTTTAATTCCATTTGGATTA
CATCATATTTTCTATGCGCCATTCTGGTTTGAATTCGGAAATTACACAAATGCTGCCGGTAACTTAGTGCGTGGTGATCA
AAGTATATGGATGGCACAAATGAAAGATGGCGTTCCATTTACAGCAGGTATGTTTACTACTGGTAAATACCCATTTATGA
TGTTCGGATTACCAGCTGCTGCTTATGCTATTTATCGTCAGGCACGTCCAGAACGCAAGAAAGTTGTAGGAGGATTAATG
CTATCTGCAGCGTTAACATCATTCTTAACAGGTATTACGGAACCACTAGAGTTCTCATTCTTATTCGTTGCTCCAATTCT
TTATGTAATACACGTATTACTTGCAGGAACATCGTTCTTAATCATGCATTTATTACATGTTAAGATTGGTATGACCTTCT
CAGGTGGGTTTATCGATTATACACTTTTTGGATTATTGAATTATGATAGAACTAATGCACTATTGGTTATCCCTGTAGGC
CTTGTATATGCAGTTGTTTACTATCTATTGTTCACTTTTGCAATTAAGAAATTTAATTTAAAAACACCAGGAAGAGAAGT
TGAAGAAACAGTTAACAAAGCTTCAGAAACCTCTGAACTTCCATTCCATGTGCTTGATGCAATGGGCGGTAAAGAGAACA
TCAAGCATCTAGACGCTTGTATTACAAGACTTAGAGTTGAAGTAAAAGATAAGTCCAAAGTGGATGTCGGTGAGTTAAAA
GCGTTAGGTGCAGCTGGTGTGTTAGAAGTAGGAAACAATATGCAGGCAATCTTTGGACCTAAGTCAGATCAGATTAAACA
TGATATGGCTAGAATCATTTCAGGTGACATAACACGTCCAGAACAAACGACTGTCACTGAAGAGATGAATCCGGTGAAAG
CTGAAGAACAAATTGAAGCTGTACCAGCAGCAGCGGATCATATTGTATATGCGCCGATTACTGGTGAAGTGGTAGATTTA
TCTCAAGTACCAGATCAAGTGTTTAGTCAGAAGCTAATGGGAGATGGGGTTGCAATCATACCTTCTATCGGTGAAGTAGT
AGCACCATTCGATGGCGTTGTGAAGATGGATTTCCCGACGAAACATGCAATAGGACTTGAAGATGAGAACGGTCTTGAAG
TTTTAATTCATTTCGGATTGGAAACTGTTGGATTAAAAGGCAACGGATTTGAAATGCTCGTAGCGCCTGGTGATAAAATC
ACTAAAGGTCAGTCGTTGTTAAAAGTAGATCTGGATTATATCAGAGCGAATGCGGACAGTGATATTACCCCAATCATCTT
CACTAATTTGAATAATCAAATGATTCATGATGTCAATTATGGAAAAATTCAATCTGGTGAACGTTTACTTTCAGTTAAAT
AA

Upstream 100 bases:

>100_bases
ATGAGTTGTCACTGATACTTAGGGATCGGTGTATACTCATGCCTTTTTATATGTGACACTGCATCACTTTACATCAAAAA
CTATTTAGGAGGAATACAAT

Downstream 100 bases:

>100_bases
GTAAAATCAAGGAACATCTGTAACGATGTTCCTTGATTTTTTTTGTTATATATGGTTAAATTTCTTTATATATAATATAA
ATTATTATAAATATATTATG

Product: glucose-specific PTS system IIABC component

Products: NA

Alternate protein names: EIICBA-Glc 2; Glucoside permease IIC component; PTS system glucoside-specific EIIC component; Glucoside-specific phosphotransferase enzyme IIB component; PTS system glucoside-specific EIIB component; Glucoside-specific phosphotransferase enzyme IIA component; PTS system glucoside-specific EIIA component [H]

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MWKTFFGQLQRIGKALMLPVALLPAAGILLAFGNAMHNEQLVQIAPWLDNGFFVMLSGIMESAGQVIFDNLPLLFAIGTA
LGLAGGDGVAGLAALVGYLIMNATIGKFMGITIDDIFSYAEGAKTLGQSAKEPANALILGIPTLQTGVFGGIIMGAVAAW
CYNKFYNINMPAFLGFFAGKRFVPIITSVMAIIVGAILAIIWPPIQGGLNTLSEFLLNKNLVLTTFIFGVIERALIPFGL
HHIFYAPFWFEFGNYTNAAGNLVRGDQSIWMAQMKDGVPFTAGMFTTGKYPFMMFGLPAAAYAIYRQARPERKKVVGGLM
LSAALTSFLTGITEPLEFSFLFVAPILYVIHVLLAGTSFLIMHLLHVKIGMTFSGGFIDYTLFGLLNYDRTNALLVIPVG
LVYAVVYYLLFTFAIKKFNLKTPGREVEETVNKASETSELPFHVLDAMGGKENIKHLDACITRLRVEVKDKSKVDVGELK
ALGAAGVLEVGNNMQAIFGPKSDQIKHDMARIISGDITRPEQTTVTEEMNPVKAEEQIEAVPAAADHIVYAPITGEVVDL
SQVPDQVFSQKLMGDGVAIIPSIGEVVAPFDGVVKMDFPTKHAIGLEDENGLEVLIHFGLETVGLKGNGFEMLVAPGDKI
TKGQSLLKVDLDYIRANADSDITPIIFTNLNNQMIHDVNYGKIQSGERLLSVK

Sequences:

>Translated_693_residues
MWKTFFGQLQRIGKALMLPVALLPAAGILLAFGNAMHNEQLVQIAPWLDNGFFVMLSGIMESAGQVIFDNLPLLFAIGTA
LGLAGGDGVAGLAALVGYLIMNATIGKFMGITIDDIFSYAEGAKTLGQSAKEPANALILGIPTLQTGVFGGIIMGAVAAW
CYNKFYNINMPAFLGFFAGKRFVPIITSVMAIIVGAILAIIWPPIQGGLNTLSEFLLNKNLVLTTFIFGVIERALIPFGL
HHIFYAPFWFEFGNYTNAAGNLVRGDQSIWMAQMKDGVPFTAGMFTTGKYPFMMFGLPAAAYAIYRQARPERKKVVGGLM
LSAALTSFLTGITEPLEFSFLFVAPILYVIHVLLAGTSFLIMHLLHVKIGMTFSGGFIDYTLFGLLNYDRTNALLVIPVG
LVYAVVYYLLFTFAIKKFNLKTPGREVEETVNKASETSELPFHVLDAMGGKENIKHLDACITRLRVEVKDKSKVDVGELK
ALGAAGVLEVGNNMQAIFGPKSDQIKHDMARIISGDITRPEQTTVTEEMNPVKAEEQIEAVPAAADHIVYAPITGEVVDL
SQVPDQVFSQKLMGDGVAIIPSIGEVVAPFDGVVKMDFPTKHAIGLEDENGLEVLIHFGLETVGLKGNGFEMLVAPGDKI
TKGQSLLKVDLDYIRANADSDITPIIFTNLNNQMIHDVNYGKIQSGERLLSVK
>Mature_693_residues
MWKTFFGQLQRIGKALMLPVALLPAAGILLAFGNAMHNEQLVQIAPWLDNGFFVMLSGIMESAGQVIFDNLPLLFAIGTA
LGLAGGDGVAGLAALVGYLIMNATIGKFMGITIDDIFSYAEGAKTLGQSAKEPANALILGIPTLQTGVFGGIIMGAVAAW
CYNKFYNINMPAFLGFFAGKRFVPIITSVMAIIVGAILAIIWPPIQGGLNTLSEFLLNKNLVLTTFIFGVIERALIPFGL
HHIFYAPFWFEFGNYTNAAGNLVRGDQSIWMAQMKDGVPFTAGMFTTGKYPFMMFGLPAAAYAIYRQARPERKKVVGGLM
LSAALTSFLTGITEPLEFSFLFVAPILYVIHVLLAGTSFLIMHLLHVKIGMTFSGGFIDYTLFGLLNYDRTNALLVIPVG
LVYAVVYYLLFTFAIKKFNLKTPGREVEETVNKASETSELPFHVLDAMGGKENIKHLDACITRLRVEVKDKSKVDVGELK
ALGAAGVLEVGNNMQAIFGPKSDQIKHDMARIISGDITRPEQTTVTEEMNPVKAEEQIEAVPAAADHIVYAPITGEVVDL
SQVPDQVFSQKLMGDGVAIIPSIGEVVAPFDGVVKMDFPTKHAIGLEDENGLEVLIHFGLETVGLKGNGFEMLVAPGDKI
TKGQSLLKVDLDYIRANADSDITPIIFTNLNNQMIHDVNYGKIQSGERLLSVK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=513, Percent_Identity=48.9278752436647, Blast_Score=433, Evalue=1e-122,
Organism=Escherichia coli, GI1786894, Length=678, Percent_Identity=39.5280235988201, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1787908, Length=528, Percent_Identity=38.4469696969697, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1788757, Length=124, Percent_Identity=38.7096774193548, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790159, Length=174, Percent_Identity=36.2068965517241, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 75151; Mature: 75151

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKTFFGQLQRIGKALMLPVALLPAAGILLAFGNAMHNEQLVQIAPWLDNGFFVMLSGIM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
ESAGQVIFDNLPLLFAIGTALGLAGGDGVAGLAALVGYLIMNATIGKFMGITIDDIFSYA
HHCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EGAKTLGQSAKEPANALILGIPTLQTGVFGGIIMGAVAAWCYNKFYNINMPAFLGFFAGK
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
RFVPIITSVMAIIVGAILAIIWPPIQGGLNTLSEFLLNKNLVLTTFIFGVIERALIPFGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
HHIFYAPFWFEFGNYTNAAGNLVRGDQSIWMAQMKDGVPFTAGMFTTGKYPFMMFGLPAA
HHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHCCCCEEECCEECCCCCEEEECHHHH
AYAIYRQARPERKKVVGGLMLSAALTSFLTGITEPLEFSFLFVAPILYVIHVLLAGTSFL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IMHLLHVKIGMTFSGGFIDYTLFGLLNYDRTNALLVIPVGLVYAVVYYLLFTFAIKKFNL
HHHHHHHHHCCEECCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
KTPGREVEETVNKASETSELPFHVLDAMGGKENIKHLDACITRLRVEVKDKSKVDVGELK
CCCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCHHHHH
ALGAAGVLEVGNNMQAIFGPKSDQIKHDMARIISGDITRPEQTTVTEEMNPVKAEEQIEA
HCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHH
VPAAADHIVYAPITGEVVDLSQVPDQVFSQKLMGDGVAIIPSIGEVVAPFDGVVKMDFPT
CCCCCCCEEEECCCCCEEEHHHCCHHHHHHHHHCCCEEEECCHHHHHCCCCCEEEECCCC
KHAIGLEDENGLEVLIHFGLETVGLKGNGFEMLVAPGDKITKGQSLLKVDLDYIRANADS
CCCCCCCCCCCCEEEEEECCCEECCCCCCEEEEEECCCCCCCCCHHHHEEHHHHHCCCCC
DITPIIFTNLNNQMIHDVNYGKIQSGERLLSVK
CCCCEEEECCCCCEEECCCCCCCCCCCEEECCC
>Mature Secondary Structure
MWKTFFGQLQRIGKALMLPVALLPAAGILLAFGNAMHNEQLVQIAPWLDNGFFVMLSGIM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
ESAGQVIFDNLPLLFAIGTALGLAGGDGVAGLAALVGYLIMNATIGKFMGITIDDIFSYA
HHCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EGAKTLGQSAKEPANALILGIPTLQTGVFGGIIMGAVAAWCYNKFYNINMPAFLGFFAGK
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
RFVPIITSVMAIIVGAILAIIWPPIQGGLNTLSEFLLNKNLVLTTFIFGVIERALIPFGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
HHIFYAPFWFEFGNYTNAAGNLVRGDQSIWMAQMKDGVPFTAGMFTTGKYPFMMFGLPAA
HHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHCCCCEEECCEECCCCCEEEECHHHH
AYAIYRQARPERKKVVGGLMLSAALTSFLTGITEPLEFSFLFVAPILYVIHVLLAGTSFL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IMHLLHVKIGMTFSGGFIDYTLFGLLNYDRTNALLVIPVGLVYAVVYYLLFTFAIKKFNL
HHHHHHHHHCCEECCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
KTPGREVEETVNKASETSELPFHVLDAMGGKENIKHLDACITRLRVEVKDKSKVDVGELK
CCCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCHHHHH
ALGAAGVLEVGNNMQAIFGPKSDQIKHDMARIISGDITRPEQTTVTEEMNPVKAEEQIEA
HCCCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHH
VPAAADHIVYAPITGEVVDLSQVPDQVFSQKLMGDGVAIIPSIGEVVAPFDGVVKMDFPT
CCCCCCCEEEECCCCCEEEHHHCCHHHHHHHHHCCCEEEECCHHHHHCCCCCEEEECCCC
KHAIGLEDENGLEVLIHFGLETVGLKGNGFEMLVAPGDKITKGQSLLKVDLDYIRANADS
CCCCCCCCCCCCEEEEEECCCEECCCCCCEEEEEECCCCCCCCCHHHHEEHHHHHCCCCC
DITPIIFTNLNNQMIHDVNYGKIQSGERLLSVK
CCCCEEEECCCCCEEECCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8602153; 10974121 [H]