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The map label for this gene is ccdA [H]

Identifier: 222151248

GI number: 222151248

Start: 1100627

End: 1101301

Strand: Direct

Name: ccdA [H]

Synonym: MCCL_0999

Alternate gene names: 222151248

Gene position: 1100627-1101301 (Clockwise)

Preceding gene: 222151246

Following gene: 222151249

Centisome position: 52.35

GC content: 35.26

Gene sequence:

>675_bases
GTGAATGATATTACGATTGCGGTGGCATTTGGTGCAGGTTTATTAAGTTTTGTATCTCCATGTGTCTTGCCGATATATCC
AGCATTCTTATCTTATATAACAGGTGTTGGCTATAATGATCTGCAAGATTCGAAACTGAATCGGAATGCCCTGTTACATA
CGATATTCTTTTTACTAGGTTTTTCTGTCGTCTATATCTCTCTAGGTGTCGGTATCGGGATGTTTTCGGACTTTTTACTG
TCATATGATAATACAATACGAATGCTCGGTGGACTGCTCTGTATAATTTTCGGCTTGATAATCTTAGGTATTTTTAATCC
GAAGTTATTGATGAAAGATCGTAAATTCGAATTTAAAAATAAACCAGCAGGATTTTTAGGGTCATTTCTAGTAGGTATTG
CATTCGCTGCTGGCTGGACCCCTTGTATGGGACCGATTATTGGAGTTATTTTTTCTATGGCAGCTGTGAATCAATCATTA
GCACTCGTTTACATGACCATGTATGTATTAGGGTTCTGTATTCCATTTTTCCTGCTGACATTTTTTATAACTAAAATTAA
TATATTAAAGAAATATAGTCAGTTGTTAACTAAAGTTGGAGGGGTTATAATGATAATCATGGGCTTATTGCTATTCTTTG
ATAAGCTGACGGTAATCAATCAGTACTTTAGTTGA

Upstream 100 bases:

>100_bases
AATCATATTTCATCCGCTTTTTGTCACATTTAAGTCATAAAGCACATCTTAATTTGAAATGAATATTTGCTAAAATAGAA
GTGAATGGAGGTTTTTTTAG

Downstream 100 bases:

>100_bases
AAGTAGGTCAAATCATGTATTTTATCGTTTCTATGCTTGTTGCATTATTTATGGGTATGGCTGTTATTATTGTCAGGATG
AAGGCACAGAATTATCCGAC

Product: holocytochrome C synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MNDITIAVAFGAGLLSFVSPCVLPIYPAFLSYITGVGYNDLQDSKLNRNALLHTIFFLLGFSVVYISLGVGIGMFSDFLL
SYDNTIRMLGGLLCIIFGLIILGIFNPKLLMKDRKFEFKNKPAGFLGSFLVGIAFAAGWTPCMGPIIGVIFSMAAVNQSL
ALVYMTMYVLGFCIPFFLLTFFITKINILKKYSQLLTKVGGVIMIIMGLLLFFDKLTVINQYFS

Sequences:

>Translated_224_residues
MNDITIAVAFGAGLLSFVSPCVLPIYPAFLSYITGVGYNDLQDSKLNRNALLHTIFFLLGFSVVYISLGVGIGMFSDFLL
SYDNTIRMLGGLLCIIFGLIILGIFNPKLLMKDRKFEFKNKPAGFLGSFLVGIAFAAGWTPCMGPIIGVIFSMAAVNQSL
ALVYMTMYVLGFCIPFFLLTFFITKINILKKYSQLLTKVGGVIMIIMGLLLFFDKLTVINQYFS
>Mature_224_residues
MNDITIAVAFGAGLLSFVSPCVLPIYPAFLSYITGVGYNDLQDSKLNRNALLHTIFFLLGFSVVYISLGVGIGMFSDFLL
SYDNTIRMLGGLLCIIFGLIILGIFNPKLLMKDRKFEFKNKPAGFLGSFLVGIAFAAGWTPCMGPIIGVIFSMAAVNQSL
ALVYMTMYVLGFCIPFFLLTFFITKINILKKYSQLLTKVGGVIMIIMGLLLFFDKLTVINQYFS

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 24725; Mature: 24725

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDITIAVAFGAGLLSFVSPCVLPIYPAFLSYITGVGYNDLQDSKLNRNALLHTIFFLLG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
FSVVYISLGVGIGMFSDFLLSYDNTIRMLGGLLCIIFGLIILGIFNPKLLMKDRKFEFKN
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
KPAGFLGSFLVGIAFAAGWTPCMGPIIGVIFSMAAVNQSLALVYMTMYVLGFCIPFFLLT
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFITKINILKKYSQLLTKVGGVIMIIMGLLLFFDKLTVINQYFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNDITIAVAFGAGLLSFVSPCVLPIYPAFLSYITGVGYNDLQDSKLNRNALLHTIFFLLG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
FSVVYISLGVGIGMFSDFLLSYDNTIRMLGGLLCIIFGLIILGIFNPKLLMKDRKFEFKN
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
KPAGFLGSFLVGIAFAAGWTPCMGPIIGVIFSMAAVNQSLALVYMTMYVLGFCIPFFLLT
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFITKINILKKYSQLLTKVGGVIMIIMGLLLFFDKLTVINQYFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]