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The map label for this gene is tkt [H]

Identifier: 222151246

GI number: 222151246

Start: 1097540

End: 1099525

Strand: Direct

Name: tkt [H]

Synonym: MCCL_0997

Alternate gene names: 222151246

Gene position: 1097540-1099525 (Clockwise)

Preceding gene: 222151245

Following gene: 222151248

Centisome position: 52.21

GC content: 41.54

Gene sequence:

>1986_bases
ATGTTTAATGAAAAAGATCAATTGGCAGTAGATAGTATTAGAGCTTTAAGTATCGATCAGATTGAGGAAGCGAATTCAGG
CCATCCGGGGTTACCTATGGGTGCGGCACCTATGGCTTACACTTTATGGACACGTCATCTTAATTTCAATCCGTCATCAC
ATCATTTCTTCGATAGAGATCGATTTGTACTATCAGCAGGACACGGTTCAGCTCTGTTATATTCATTGCTGCATGTTTCT
GGTGGGCTCGAAATAGAGGAGCTTAAGCAGTTTAGACAATGGGACTCTAAAACTCCAGGGCATCCGGAGTACCGTCATAC
TAAAGGTGTAGAGATCACAACAGGGCCACTAGGTCAAGGATTTGCGATGAGCGTCGGCATGGCGATGGCAGAAAAGCATC
TCGCTGCAAGCTTCAATCAGCAGTCAGATATTATTGATCATTATACGTATGCATTAGTTTCAGATGGAGACTTGATGGAA
GGTATATCGCACGAAGCTGCAAGTCTTGCAGGTCACTTAAAACTTAATAAATTAATCGCTTTATATGATTCGAATGATAT
CTCTTTAGATGGAGAGCTGAATAAAGCATTCTCTGAAGATGTTAAAGGGCGTTTCGAAAGCTATGGCTGGGAACATATTT
TAGTGTCGGATGGTAATGATATGGAAGCCATTGATAAAGCCATTTCAGCAGCAAAATCAAGTGATAGACCTACGATCATT
GAAGTTAAGACTATTATCGGTTATGGTTCTCCGAATAAGCAAGGAACGAATGGTATCCACGGGGCTCCATTAGGAGGAGA
TGAGCGTAAGCTTGTATTTGAAGCATACGGTTTAGATGCAGATAAGAAATTCCATGTAGATCCAGCTGTATATGAAATAT
TCCAGCAGACGATGCTAAAACGTGCAAATGAAAAAGAGCAGTTATGGAATGAGAAATTTACACAATTAGAAAAAGAAAAT
GCTGAACTAGCACAACAGCTTAAACAAGCAATAGCTGGGGAATTAAATGCTGATTATGCGGAAGCGTTACCGGTATATGA
GGCTGGTACATCAGCTGCTACCCGTGCAACGAGTGGTGATATGATCCAGGCAATCGCAAAAACAGTTCCTTCATTCTTTG
GGGGATCTGCAGATTTAGCATCTTCTAATAAGTCAAATGTTAAGGATACAGGAGACTTTTCGGCTGAAACGCCTGAAGGA
AAGAATGTCTGGTTCGGTGTCAGAGAGTTTGCAATGGGTGCTGCTTTAAATGGTATGGCTGCTCACGGAGGACTTAAAGT
ATACGGTGCGACATTCTTTGTGTTTAGTGACTATTTGAAGCCGGCAGTAAGATTATCAGCGTTAATGGGCTTACCGGTCA
CATATGTATTTACACATGACTCAATAGCAGTAGGTGAAGACGGCCCGACACATGAACCGATCGAGCAGCTGGCTGGTTTG
CGTGCGATTCCGAACTTAAATGTAATTCGTCCGGCAGATGGTAATGAAAGCCGTGCCGCCTGGAAAATTGCGCTTGAATC
AACTGATGCACCGACTGCACTTGTCCTTACGCGTCAGAACCTAACAGCGATTGATATTGAACAGGATAAATTAGAAGCGG
GTGTTGCACGTGGTGGCTATGTTGTTTATCAATCTGAGCATCCAGAGATATTAATAGTTGCAACTGGTTCAGAAGTGAAT
TTAGCGATTGATGCAGCAAAAGTATTAGAAAATCAAGGTAAAGGTGTTCAAGTGGTATCAATGCCGAACACTCAGAAATT
TGATGCACAAGACAAAGCATACAAAGAAGAAGTATTACCATCTTCAATTAAGCAGCGTGTGGCAATTGAAATGGCTGCTT
CTGACAGCTGGTATAAATACGTTGGTCTGGATGGACTTGTAATTGGTATTGATAAGTTCGGTGCAAGCGCACCTGGAGAA
TTAGTAATGGAGAAATATGGATTCACTGTAGAAAATGTTGTAAATAACATTTTGAATATGAAGTAA

Upstream 100 bases:

>100_bases
TCATCGACCCTGAAGGTAATGATGTGACACCTGACAAGGTGAAAGAAATTCAGAAATTAAATAATATCAGAAAATAAATT
TTGTAGATAGGAGCATTTAT

Downstream 100 bases:

>100_bases
ATAAAAGGCTGTTTATCAGCCTTTTATTATTTATAGAAAACATATTGAAAAAAAAGTTTGTTTTTAGTAAAATTTTAATG
GTATAAGAAAGTGGGTGAAC

Product: transketolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MFNEKDQLAVDSIRALSIDQIEEANSGHPGLPMGAAPMAYTLWTRHLNFNPSSHHFFDRDRFVLSAGHGSALLYSLLHVS
GGLEIEELKQFRQWDSKTPGHPEYRHTKGVEITTGPLGQGFAMSVGMAMAEKHLAASFNQQSDIIDHYTYALVSDGDLME
GISHEAASLAGHLKLNKLIALYDSNDISLDGELNKAFSEDVKGRFESYGWEHILVSDGNDMEAIDKAISAAKSSDRPTII
EVKTIIGYGSPNKQGTNGIHGAPLGGDERKLVFEAYGLDADKKFHVDPAVYEIFQQTMLKRANEKEQLWNEKFTQLEKEN
AELAQQLKQAIAGELNADYAEALPVYEAGTSAATRATSGDMIQAIAKTVPSFFGGSADLASSNKSNVKDTGDFSAETPEG
KNVWFGVREFAMGAALNGMAAHGGLKVYGATFFVFSDYLKPAVRLSALMGLPVTYVFTHDSIAVGEDGPTHEPIEQLAGL
RAIPNLNVIRPADGNESRAAWKIALESTDAPTALVLTRQNLTAIDIEQDKLEAGVARGGYVVYQSEHPEILIVATGSEVN
LAIDAAKVLENQGKGVQVVSMPNTQKFDAQDKAYKEEVLPSSIKQRVAIEMAASDSWYKYVGLDGLVIGIDKFGASAPGE
LVMEKYGFTVENVVNNILNMK

Sequences:

>Translated_661_residues
MFNEKDQLAVDSIRALSIDQIEEANSGHPGLPMGAAPMAYTLWTRHLNFNPSSHHFFDRDRFVLSAGHGSALLYSLLHVS
GGLEIEELKQFRQWDSKTPGHPEYRHTKGVEITTGPLGQGFAMSVGMAMAEKHLAASFNQQSDIIDHYTYALVSDGDLME
GISHEAASLAGHLKLNKLIALYDSNDISLDGELNKAFSEDVKGRFESYGWEHILVSDGNDMEAIDKAISAAKSSDRPTII
EVKTIIGYGSPNKQGTNGIHGAPLGGDERKLVFEAYGLDADKKFHVDPAVYEIFQQTMLKRANEKEQLWNEKFTQLEKEN
AELAQQLKQAIAGELNADYAEALPVYEAGTSAATRATSGDMIQAIAKTVPSFFGGSADLASSNKSNVKDTGDFSAETPEG
KNVWFGVREFAMGAALNGMAAHGGLKVYGATFFVFSDYLKPAVRLSALMGLPVTYVFTHDSIAVGEDGPTHEPIEQLAGL
RAIPNLNVIRPADGNESRAAWKIALESTDAPTALVLTRQNLTAIDIEQDKLEAGVARGGYVVYQSEHPEILIVATGSEVN
LAIDAAKVLENQGKGVQVVSMPNTQKFDAQDKAYKEEVLPSSIKQRVAIEMAASDSWYKYVGLDGLVIGIDKFGASAPGE
LVMEKYGFTVENVVNNILNMK
>Mature_661_residues
MFNEKDQLAVDSIRALSIDQIEEANSGHPGLPMGAAPMAYTLWTRHLNFNPSSHHFFDRDRFVLSAGHGSALLYSLLHVS
GGLEIEELKQFRQWDSKTPGHPEYRHTKGVEITTGPLGQGFAMSVGMAMAEKHLAASFNQQSDIIDHYTYALVSDGDLME
GISHEAASLAGHLKLNKLIALYDSNDISLDGELNKAFSEDVKGRFESYGWEHILVSDGNDMEAIDKAISAAKSSDRPTII
EVKTIIGYGSPNKQGTNGIHGAPLGGDERKLVFEAYGLDADKKFHVDPAVYEIFQQTMLKRANEKEQLWNEKFTQLEKEN
AELAQQLKQAIAGELNADYAEALPVYEAGTSAATRATSGDMIQAIAKTVPSFFGGSADLASSNKSNVKDTGDFSAETPEG
KNVWFGVREFAMGAALNGMAAHGGLKVYGATFFVFSDYLKPAVRLSALMGLPVTYVFTHDSIAVGEDGPTHEPIEQLAGL
RAIPNLNVIRPADGNESRAAWKIALESTDAPTALVLTRQNLTAIDIEQDKLEAGVARGGYVVYQSEHPEILIVATGSEVN
LAIDAAKVLENQGKGVQVVSMPNTQKFDAQDKAYKEEVLPSSIKQRVAIEMAASDSWYKYVGLDGLVIGIDKFGASAPGE
LVMEKYGFTVENVVNNILNMK

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=574, Percent_Identity=25.4355400696864, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4507521, Length=574, Percent_Identity=25.4355400696864, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI133778974, Length=587, Percent_Identity=25.5536626916525, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI225637463, Length=516, Percent_Identity=23.2558139534884, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI225637459, Length=516, Percent_Identity=23.2558139534884, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI225637461, Length=516, Percent_Identity=23.2558139534884, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI48994911, Length=663, Percent_Identity=49.1704374057315, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1788808, Length=653, Percent_Identity=47.0137825421133, Blast_Score=588, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI17539652, Length=668, Percent_Identity=24.8502994011976, Blast_Score=157, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6325331, Length=663, Percent_Identity=47.0588235294118, Blast_Score=575, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6319593, Length=666, Percent_Identity=44.8948948948949, Blast_Score=550, Evalue=1e-157,
Organism=Drosophila melanogaster, GI45551847, Length=580, Percent_Identity=26.8965517241379, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI45550715, Length=580, Percent_Identity=26.8965517241379, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24645119, Length=552, Percent_Identity=26.8115942028986, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24666278, Length=584, Percent_Identity=25.6849315068493, Blast_Score=162, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71740; Mature: 71740

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNEKDQLAVDSIRALSIDQIEEANSGHPGLPMGAAPMAYTLWTRHLNFNPSSHHFFDRD
CCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCEEEEEHEEECCCCCCCCCCCCC
RFVLSAGHGSALLYSLLHVSGGLEIEELKQFRQWDSKTPGHPEYRHTKGVEITTGPLGQG
CEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCC
FAMSVGMAMAEKHLAASFNQQSDIIDHYTYALVSDGDLMEGISHEAASLAGHLKLNKLIA
HHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEEE
LYDSNDISLDGELNKAFSEDVKGRFESYGWEHILVSDGNDMEAIDKAISAAKSSDRPTII
EECCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEE
EVKTIIGYGSPNKQGTNGIHGAPLGGDERKLVFEAYGLDADKKFHVDPAVYEIFQQTMLK
EEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEECCCHHHHHHHHHHHHH
RANEKEQLWNEKFTQLEKENAELAQQLKQAIAGELNADYAEALPVYEAGTSAATRATSGD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEECCCCHHHCCCCCH
MIQAIAKTVPSFFGGSADLASSNKSNVKDTGDFSAETPEGKNVWFGVREFAMGAALNGMA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCHH
AHGGLKVYGATFFVFSDYLKPAVRLSALMGLPVTYVFTHDSIAVGEDGPTHEPIEQLAGL
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHCC
RAIPNLNVIRPADGNESRAAWKIALESTDAPTALVLTRQNLTAIDIEQDKLEAGVARGGY
CCCCCCCEEECCCCCCCCEEEEEEEECCCCCEEEEEEECCCEEEECCHHHHHHHHCCCCE
VVYQSEHPEILIVATGSEVNLAIDAAKVLENQGKGVQVVSMPNTQKFDAQDKAYKEEVLP
EEEECCCCCEEEEEECCCEEEEEHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCH
SSIKQRVAIEMAASDSWYKYVGLDGLVIGIDKFGASAPGELVMEKYGFTVENVVNNILNM
HHHHHHEEEEEECCCCEEEEECCCEEEEEEHHCCCCCCHHHHHHHHCCCHHHHHHHHHCC
K
C
>Mature Secondary Structure
MFNEKDQLAVDSIRALSIDQIEEANSGHPGLPMGAAPMAYTLWTRHLNFNPSSHHFFDRD
CCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCEEEEEHEEECCCCCCCCCCCCC
RFVLSAGHGSALLYSLLHVSGGLEIEELKQFRQWDSKTPGHPEYRHTKGVEITTGPLGQG
CEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCC
FAMSVGMAMAEKHLAASFNQQSDIIDHYTYALVSDGDLMEGISHEAASLAGHLKLNKLIA
HHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEEE
LYDSNDISLDGELNKAFSEDVKGRFESYGWEHILVSDGNDMEAIDKAISAAKSSDRPTII
EECCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEE
EVKTIIGYGSPNKQGTNGIHGAPLGGDERKLVFEAYGLDADKKFHVDPAVYEIFQQTMLK
EEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEECCCHHHHHHHHHHHHH
RANEKEQLWNEKFTQLEKENAELAQQLKQAIAGELNADYAEALPVYEAGTSAATRATSGD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEECCCCHHHCCCCCH
MIQAIAKTVPSFFGGSADLASSNKSNVKDTGDFSAETPEGKNVWFGVREFAMGAALNGMA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCHH
AHGGLKVYGATFFVFSDYLKPAVRLSALMGLPVTYVFTHDSIAVGEDGPTHEPIEQLAGL
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHCC
RAIPNLNVIRPADGNESRAAWKIALESTDAPTALVLTRQNLTAIDIEQDKLEAGVARGGY
CCCCCCCEEECCCCCCCCEEEEEEEECCCCCEEEEEEECCCEEEECCHHHHHHHHCCCCE
VVYQSEHPEILIVATGSEVNLAIDAAKVLENQGKGVQVVSMPNTQKFDAQDKAYKEEVLP
EEEECCCCCEEEEEECCCEEEEEHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCH
SSIKQRVAIEMAASDSWYKYVGLDGLVIGIDKFGASAPGELVMEKYGFTVENVVNNILNM
HHHHHHEEEEEECCCCEEEEECCCEEEEEEHHCCCCCCHHHHHHHHCCCHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA