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The map label for this gene is ftsK [H]

Identifier: 222151116

GI number: 222151116

Start: 954353

End: 956593

Strand: Direct

Name: ftsK [H]

Synonym: MCCL_0867

Alternate gene names: 222151116

Gene position: 954353-956593 (Clockwise)

Preceding gene: 222151115

Following gene: 222151117

Centisome position: 45.4

GC content: 39.71

Gene sequence:

>2241_bases
ATGGCTATTAAGAAGAAAACACGTAAGAAAAAACGTAATACAAAGAAGAAGGATAATATACCTTATCGTTATTTGATCGC
TCTTTTGATTATTGGACTTATCTTTGCCGCCATCTTTCAATTTGGAATCATTGGCGTAGGCATTGACAGTCTATTTACTT
ACTTTACAGGTAGTGCGCGGTTTTATGTCTATATCCTGATTCTTTTAATGACGATATACTATACCGTAAATCAAAAGATG
ATACCATTGAATCGTCGCGTCAATGGCTGGTTATTGATGCTTGTGGCTTTACCTTCATTTTTACAGGTTATAGAACATAT
ATTAAATGGTAAGCCCATCCTGCCGTTATTTAATTCGATTTATGAGCTTCAATCCCGTTCAGGTATTCATTTTTTCGGTG
GCGGTATCATAGGTTATCTATATGATATCGTGTTTAGTACATTAATCAGTACACTCGGCTCTCTGTTATTATCGTTACTG
ATGATAACCATCAGTATATTGCTCATTCTTGGAAGGTCTATCCGTCTCGCTGCAGAAAGAACATTCCTTTGGATCATGAA
ATATCTACGTCTGTTAATAGATAAAGTTACAGACTTTGCAAAAAAGGACAGAAACACACATCATAATGAAGTCATCGATG
TGTCTGACCTCCCTGTGCTTACTCAAGATGCTGAGGATATTCCGATTTATGATAGCGTACAGCAATTTGATAGCAATGAA
GATCTTGGTGAAGGTGAAGCGTTTATAAGTACAAGTAAAGATGTACCGTCTAACACGGGAAATGTGAATCTTGAATCAGT
GGTGCATACAAGTGCAACAACAGAAGATGAGAATCCAAACTACAAGCTCCCACCGATTACGTTATTACATCCTGCTGCAG
AAAAAGCAAAGAACAATATGCAGGACGTAAAAAAACGTGGACAACTATTAGAAACGACTTTAAAGAATTTTGGGGTCAAT
GCAAAGGTAAGTCAGATTAGGATTGGACCAGCTGTTACACAATACGAAGTACAGCCTGCTATGGGCGTTAAAGTCAGTCG
CATCGTTAATCTGCACAACGATATCGCACTCGCACTTGCTGCAAAAGATATTCGTATAGAAGCGCCGATACCTGGCAAAT
CGGCAGTCGGGATAGAAGTCCCGAATCAGTCGGTGTCTATGGTTACTCTACGTGAAGTGCTGGAAGCATCCCCTGTAAAC
GATAATAAGCTGAAGGTTGTGCTTGGAAGAGATATCTCGGGAGAAGCAATCACTGCAGAACTTGATAAGATGCCACATTT
ACTTGTGGCTGGCGCAACCGGAAGCGGTAAGTCGGTGTGTATTAATGGTATTATTACAAGTATACTCATGAATGCAAAGC
CTCATGAAGTGAAGCTAATGATGATCGATCCGAAAATGGTTGAATTAAACGTCTATAATGGCATACCGCATCTACTGACG
CCAGTTGTCACGAATCCTCAGAAAGCTGCTCAGGCACTGCAGAAGATTGTCGGTGAGATGGAACGTCGTTACGATTTATT
CAGTCATACCGGTACACGAAATATAAAAGGATATAACGCATATCTCGAAAGACAGAATCATGAAATGAATGAGAAGAATG
CAAAGCTTCCATATATAGTAGTTATTGTTGATGAACTAGCTGATTTGATGATGGTGGCAAGTAAAGATGTAGAAGCAGCC
ATTATGCGACTGGCACAGATGGCGCGTGCAGCAGGAATCCATCTGATTATTGCGACCCAGCGCCCATCTGTCGATGTAAT
CACTGGATTAATTAAAGCAAATATTCCTTCGCGAATTGCCTTTAGTGTAAGTAGTGCTGTAGATTCAAGGACAATTTTGG
ATAGTCAAGGTGCAGAGAAGCTGCTCGGTAAAGGAGATATGTTATATTTACCTTATGGACAATCTAAACCGACACGTATA
CAAGGGGCTTTTTTATCAGATGCTGAAGTAGAAGCTATCGTTCAGTTTGTTACAAGACAGCAGTCTGCAAATTATGTTGA
AGAGATGACACCTGCAGACGTAAAAGAAAGCGAAAATGATTCAGAAGATGAACTTTATCTGGAAGTATATGCATTTGTAA
TCGAAAAGCAGAAAGCTTCAGCCAGTTTACTGCAGAGACAGTTTAGAATTGGATACAATAGAGCGGCTCGTTTAATTGAT
GAGCTGGAAGCAAATGGAGTAATTGGTCCCGCTACAGGGAGTAAACCAAGAGCAGTTTTAATAGAACAAATTGAAGAATA
G

Upstream 100 bases:

>100_bases
AACGCCGTCCGATGATTATTCCTGTAATTTCAGAAATTTAAATTATAAATAAACAAGCTATTAATAGCTTGTTTATTTAT
TTAGTAAGGTAGGTGTCAGT

Downstream 100 bases:

>100_bases
GAGCGTTAACATTGTCTGTAAATCATGAAGTTGTCTATACGAAGGACTGGATTCTATCAAAGATTTATTCAGGAGATTTC
AATAGTCATAAACCGTTACC

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 746; Mature: 745

Protein sequence:

>746_residues
MAIKKKTRKKKRNTKKKDNIPYRYLIALLIIGLIFAAIFQFGIIGVGIDSLFTYFTGSARFYVYILILLMTIYYTVNQKM
IPLNRRVNGWLLMLVALPSFLQVIEHILNGKPILPLFNSIYELQSRSGIHFFGGGIIGYLYDIVFSTLISTLGSLLLSLL
MITISILLILGRSIRLAAERTFLWIMKYLRLLIDKVTDFAKKDRNTHHNEVIDVSDLPVLTQDAEDIPIYDSVQQFDSNE
DLGEGEAFISTSKDVPSNTGNVNLESVVHTSATTEDENPNYKLPPITLLHPAAEKAKNNMQDVKKRGQLLETTLKNFGVN
AKVSQIRIGPAVTQYEVQPAMGVKVSRIVNLHNDIALALAAKDIRIEAPIPGKSAVGIEVPNQSVSMVTLREVLEASPVN
DNKLKVVLGRDISGEAITAELDKMPHLLVAGATGSGKSVCINGIITSILMNAKPHEVKLMMIDPKMVELNVYNGIPHLLT
PVVTNPQKAAQALQKIVGEMERRYDLFSHTGTRNIKGYNAYLERQNHEMNEKNAKLPYIVVIVDELADLMMVASKDVEAA
IMRLAQMARAAGIHLIIATQRPSVDVITGLIKANIPSRIAFSVSSAVDSRTILDSQGAEKLLGKGDMLYLPYGQSKPTRI
QGAFLSDAEVEAIVQFVTRQQSANYVEEMTPADVKESENDSEDELYLEVYAFVIEKQKASASLLQRQFRIGYNRAARLID
ELEANGVIGPATGSKPRAVLIEQIEE

Sequences:

>Translated_746_residues
MAIKKKTRKKKRNTKKKDNIPYRYLIALLIIGLIFAAIFQFGIIGVGIDSLFTYFTGSARFYVYILILLMTIYYTVNQKM
IPLNRRVNGWLLMLVALPSFLQVIEHILNGKPILPLFNSIYELQSRSGIHFFGGGIIGYLYDIVFSTLISTLGSLLLSLL
MITISILLILGRSIRLAAERTFLWIMKYLRLLIDKVTDFAKKDRNTHHNEVIDVSDLPVLTQDAEDIPIYDSVQQFDSNE
DLGEGEAFISTSKDVPSNTGNVNLESVVHTSATTEDENPNYKLPPITLLHPAAEKAKNNMQDVKKRGQLLETTLKNFGVN
AKVSQIRIGPAVTQYEVQPAMGVKVSRIVNLHNDIALALAAKDIRIEAPIPGKSAVGIEVPNQSVSMVTLREVLEASPVN
DNKLKVVLGRDISGEAITAELDKMPHLLVAGATGSGKSVCINGIITSILMNAKPHEVKLMMIDPKMVELNVYNGIPHLLT
PVVTNPQKAAQALQKIVGEMERRYDLFSHTGTRNIKGYNAYLERQNHEMNEKNAKLPYIVVIVDELADLMMVASKDVEAA
IMRLAQMARAAGIHLIIATQRPSVDVITGLIKANIPSRIAFSVSSAVDSRTILDSQGAEKLLGKGDMLYLPYGQSKPTRI
QGAFLSDAEVEAIVQFVTRQQSANYVEEMTPADVKESENDSEDELYLEVYAFVIEKQKASASLLQRQFRIGYNRAARLID
ELEANGVIGPATGSKPRAVLIEQIEE
>Mature_745_residues
AIKKKTRKKKRNTKKKDNIPYRYLIALLIIGLIFAAIFQFGIIGVGIDSLFTYFTGSARFYVYILILLMTIYYTVNQKMI
PLNRRVNGWLLMLVALPSFLQVIEHILNGKPILPLFNSIYELQSRSGIHFFGGGIIGYLYDIVFSTLISTLGSLLLSLLM
ITISILLILGRSIRLAAERTFLWIMKYLRLLIDKVTDFAKKDRNTHHNEVIDVSDLPVLTQDAEDIPIYDSVQQFDSNED
LGEGEAFISTSKDVPSNTGNVNLESVVHTSATTEDENPNYKLPPITLLHPAAEKAKNNMQDVKKRGQLLETTLKNFGVNA
KVSQIRIGPAVTQYEVQPAMGVKVSRIVNLHNDIALALAAKDIRIEAPIPGKSAVGIEVPNQSVSMVTLREVLEASPVND
NKLKVVLGRDISGEAITAELDKMPHLLVAGATGSGKSVCINGIITSILMNAKPHEVKLMMIDPKMVELNVYNGIPHLLTP
VVTNPQKAAQALQKIVGEMERRYDLFSHTGTRNIKGYNAYLERQNHEMNEKNAKLPYIVVIVDELADLMMVASKDVEAAI
MRLAQMARAAGIHLIIATQRPSVDVITGLIKANIPSRIAFSVSSAVDSRTILDSQGAEKLLGKGDMLYLPYGQSKPTRIQ
GAFLSDAEVEAIVQFVTRQQSANYVEEMTPADVKESENDSEDELYLEVYAFVIEKQKASASLLQRQFRIGYNRAARLIDE
LEANGVIGPATGSKPRAVLIEQIEE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=483, Percent_Identity=49.2753623188406, Blast_Score=424, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 82670; Mature: 82539

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKKKTRKKKRNTKKKDNIPYRYLIALLIIGLIFAAIFQFGIIGVGIDSLFTYFTGSAR
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHH
FYVYILILLMTIYYTVNQKMIPLNRRVNGWLLMLVALPSFLQVIEHILNGKPILPLFNSI
HHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YELQSRSGIHFFGGGIIGYLYDIVFSTLISTLGSLLLSLLMITISILLILGRSIRLAAER
HHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TFLWIMKYLRLLIDKVTDFAKKDRNTHHNEVIDVSDLPVLTQDAEDIPIYDSVQQFDSNE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEECCCCCCCCCHHHHHHCCCCC
DLGEGEAFISTSKDVPSNTGNVNLESVVHTSATTEDENPNYKLPPITLLHPAAEKAKNNM
CCCCCCEEEECCCCCCCCCCCEEHHHEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHH
QDVKKRGQLLETTLKNFGVNAKVSQIRIGPAVTQYEVQPAMGVKVSRIVNLHNDIALALA
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHCCCEEEEEE
AKDIRIEAPIPGKSAVGIEVPNQSVSMVTLREVLEASPVNDNKLKVVLGRDISGEAITAE
EECEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEHHH
LDKMPHLLVAGATGSGKSVCINGIITSILMNAKPHEVKLMMIDPKMVELNVYNGIPHLLT
HHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEECCCCHHHHH
PVVTNPQKAAQALQKIVGEMERRYDLFSHTGTRNIKGYNAYLERQNHEMNEKNAKLPYIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEE
VIVDELADLMMVASKDVEAAIMRLAQMARAAGIHLIIATQRPSVDVITGLIKANIPSRIA
EEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCHHH
FSVSSAVDSRTILDSQGAEKLLGKGDMLYLPYGQSKPTRIQGAFLSDAEVEAIVQFVTRQ
HHHHHHHCCHHHHCCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHH
QSANYVEEMTPADVKESENDSEDELYLEVYAFVIEKQKASASLLQRQFRIGYNRAARLID
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ELEANGVIGPATGSKPRAVLIEQIEE
HHHCCCEEECCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
AIKKKTRKKKRNTKKKDNIPYRYLIALLIIGLIFAAIFQFGIIGVGIDSLFTYFTGSAR
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHH
FYVYILILLMTIYYTVNQKMIPLNRRVNGWLLMLVALPSFLQVIEHILNGKPILPLFNSI
HHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YELQSRSGIHFFGGGIIGYLYDIVFSTLISTLGSLLLSLLMITISILLILGRSIRLAAER
HHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TFLWIMKYLRLLIDKVTDFAKKDRNTHHNEVIDVSDLPVLTQDAEDIPIYDSVQQFDSNE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEECCCCCCCCCHHHHHHCCCCC
DLGEGEAFISTSKDVPSNTGNVNLESVVHTSATTEDENPNYKLPPITLLHPAAEKAKNNM
CCCCCCEEEECCCCCCCCCCCEEHHHEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHH
QDVKKRGQLLETTLKNFGVNAKVSQIRIGPAVTQYEVQPAMGVKVSRIVNLHNDIALALA
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHCCCEEEEEE
AKDIRIEAPIPGKSAVGIEVPNQSVSMVTLREVLEASPVNDNKLKVVLGRDISGEAITAE
EECEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEHHH
LDKMPHLLVAGATGSGKSVCINGIITSILMNAKPHEVKLMMIDPKMVELNVYNGIPHLLT
HHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEECCCCHHHHH
PVVTNPQKAAQALQKIVGEMERRYDLFSHTGTRNIKGYNAYLERQNHEMNEKNAKLPYIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEE
VIVDELADLMMVASKDVEAAIMRLAQMARAAGIHLIIATQRPSVDVITGLIKANIPSRIA
EEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCHHH
FSVSSAVDSRTILDSQGAEKLLGKGDMLYLPYGQSKPTRIQGAFLSDAEVEAIVQFVTRQ
HHHHHHHCCHHHHCCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHH
QSANYVEEMTPADVKESENDSEDELYLEVYAFVIEKQKASASLLQRQFRIGYNRAARLID
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ELEANGVIGPATGSKPRAVLIEQIEE
HHHCCCEEECCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA