Click here to switch to the map view.

The map label for this gene is hslV

Identifier: 222151086

GI number: 222151086

Start: 913942

End: 914484

Strand: Direct

Name: hslV

Synonym: MCCL_0837

Alternate gene names: 222151086

Gene position: 913942-914484 (Clockwise)

Preceding gene: 222151085

Following gene: 222151087

Centisome position: 43.47

GC content: 42.36

Gene sequence:

>543_bases
ATGAATAATCAATTACATGCTACGACAATCTTTGCAATCAGACATAATGGTCGAGCGGCGATGAGCGGTGATGGACAAGT
GACACTCGGGCAGCAGGTCATTATGAAACAGACTGCAAGAAAAGTGAGAAGACTGTTTAATGATGAAGTCGTTGCAGGAT
TTGCCGGCAGTGTTGCAGATGCATTTACACTATTTGAAATGTTTGAAGCAAAGCTTTATGAATATAATGGTAACTTATCA
CGTGCAGCAGTTGAGCTGGCAAAAGAATGGCGTGGTGACAAAATGTTACGTCAACTTGAAGCGATGCTGATTGTTATGAA
TAAAGATGAACTGCTTGTCGTGAGCGGTACAGGCGAAGTGATACAGCCTGATGACGATATTATTGCGATTGGTTCAGGCG
GGAATTACGCGCTAAGTGCGGGGCGTGCATTAAAGCGCCATGCAAGCACGTTGAGCGCGCGTGATATTGCACAGGCTTCT
TTAGAAACAGCAGCTGATATATGTGTATTCACAAATCATAATATTATTATTGAAGAAATTTAG

Upstream 100 bases:

>100_bases
ATGTCAATTTATCGACAACAAGCAAATATACGCATATAACGAAAGCACACTTAAGAAATTCATATTTAAGCGCACATCCA
AGAGCATAAGGAGTGGAAGA

Downstream 100 bases:

>100_bases
GAGGCATATCATGAAGTCAGCGAACTTAACGCCAAGACAAATCGTTAGTCATCTCGATGAACATATTATCGGTCAGCAGG
ATGCAAAGAGGAAGGTGGCG

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNNQLHATTIFAIRHNGRAAMSGDGQVTLGQQVIMKQTARKVRRLFNDEVVAGFAGSVADAFTLFEMFEAKLYEYNGNLS
RAAVELAKEWRGDKMLRQLEAMLIVMNKDELLVVSGTGEVIQPDDDIIAIGSGGNYALSAGRALKRHASTLSARDIAQAS
LETAADICVFTNHNIIIEEI

Sequences:

>Translated_180_residues
MNNQLHATTIFAIRHNGRAAMSGDGQVTLGQQVIMKQTARKVRRLFNDEVVAGFAGSVADAFTLFEMFEAKLYEYNGNLS
RAAVELAKEWRGDKMLRQLEAMLIVMNKDELLVVSGTGEVIQPDDDIIAIGSGGNYALSAGRALKRHASTLSARDIAQAS
LETAADICVFTNHNIIIEEI
>Mature_180_residues
MNNQLHATTIFAIRHNGRAAMSGDGQVTLGQQVIMKQTARKVRRLFNDEVVAGFAGSVADAFTLFEMFEAKLYEYNGNLS
RAAVELAKEWRGDKMLRQLEAMLIVMNKDELLVVSGTGEVIQPDDDIIAIGSGGNYALSAGRALKRHASTLSARDIAQAS
LETAADICVFTNHNIIIEEI

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=173, Percent_Identity=56.6473988439306, Blast_Score=201, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_MACCJ (B9EBD3)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560240.1
- MEROPS:   T01.007
- GeneID:   7390501
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0837
- OMA:   AADICVY
- ProtClustDB:   PRK05456
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.- [C]

Molecular weight: Translated: 19656; Mature: 19656

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: ACT_SITE 8-8

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQLHATTIFAIRHNGRAAMSGDGQVTLGQQVIMKQTARKVRRLFNDEVVAGFAGSVAD
CCCCEEEEEEEEEEECCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AFTLFEMFEAKLYEYNGNLSRAAVELAKEWRGDKMLRQLEAMLIVMNKDELLVVSGTGEV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHEEEEECCCCEEEEECCCCE
IQPDDDIIAIGSGGNYALSAGRALKRHASTLSARDIAQASLETAADICVFTNHNIIIEEI
ECCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEC
>Mature Secondary Structure
MNNQLHATTIFAIRHNGRAAMSGDGQVTLGQQVIMKQTARKVRRLFNDEVVAGFAGSVAD
CCCCEEEEEEEEEEECCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AFTLFEMFEAKLYEYNGNLSRAAVELAKEWRGDKMLRQLEAMLIVMNKDELLVVSGTGEV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHEEEEECCCCEEEEECCCCE
IQPDDDIIAIGSGGNYALSAGRALKRHASTLSARDIAQASLETAADICVFTNHNIIIEEI
ECCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA