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The map label for this gene is sucD [H]

Identifier: 222151081

GI number: 222151081

Start: 907452

End: 908360

Strand: Direct

Name: sucD [H]

Synonym: MCCL_0832

Alternate gene names: 222151081

Gene position: 907452-908360 (Clockwise)

Preceding gene: 222151080

Following gene: 222151082

Centisome position: 43.16

GC content: 39.6

Gene sequence:

>909_bases
GTGGGAGTATTTATTGATAAAGATACGAAAGTAATCGTACAAGGTATTACAGGATCAACAGCATTATTTCATACGAAACA
AATGATAGAATATGGTACTAAAATTGTTGCAGGTGTTACACCGGGTAAAGGTGGCATGGAAGTTGAAGGCGTACCTGTAT
TCAATACAGTTGAAGAGGCAGTAAAAGCTACAGGTGCTACAGTTTCAGTTATTTATGTTCCAGCACCATTTGCTGCAGAT
GCAATTGTTGAATGTGTTGATGCAGAATTAGATTTAGCAATTTGTATTACTGAACATATTCCGGTCTTAGATATGGTTAA
AGTAAAACGTTATATGCAAGGTAAGAAAACACGCTTAGTTGGACCGAACTGTCCAGGTGTTATTACTGCAGACGAATGTA
AAATAGGAATTATGCCAGGATACATTCATAAAAAAGGACATGTGGGCGTTGTTAGCCGTTCTGGAACATTGACTTATGAA
GCAGTGCATCAGTTAACACAAGCAGGTATCGGTCAAACAACAGCTGTAGGTATTGGTGGAGACCCTGTAAACGGTACAAA
CTTCATCGATGCGTTAGAAGCGTTTAATAATGACCCTGAAACATTGGCTGTTGTCATGATCGGTGAAATTGGTGGAACAG
CTGAAGAAGAAGCTGCTGAATGGGTTAAAGCGAACATGACGAAACCTGTCGTAGGCTTTATCGGCGGTCAGACAGCACCT
CCTGGTAAACGTATGGGACATGCTGGTGCAATCATTTCAGGTGGTAAAGGTACGGCTGAAGAAAAGATTAAAACAATGAA
CGCTTGCGGTATTAAAACTGCAGCGACTCCTTCTGAAATTGGTTCGACATTAATCGAACGTATTAAAGAAGAAGATGGCT
TATATGACAAATGTTTAACAGTTAAATAA

Upstream 100 bases:

>100_bases
TAATTCAGGATTAGCAATTACACCTGCAAGCACAATGGCTGAAGGTGCACAAAAAATCGTTGAATTAGTAAAAGAAGCTA
AATAGGAAGCGGGGATAATC

Downstream 100 bases:

>100_bases
TATAGATTCCGGGCGACCCATCATTTATTTATAGGTCGCCCGGAATTTTTTTATTAATATTTACAAATATTAATATTTAG
ATGAAAAGAAATTAAAGAAC

Product: succinyl-CoA synthetase alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MGVFIDKDTKVIVQGITGSTALFHTKQMIEYGTKIVAGVTPGKGGMEVEGVPVFNTVEEAVKATGATVSVIYVPAPFAAD
AIVECVDAELDLAICITEHIPVLDMVKVKRYMQGKKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYE
AVHQLTQAGIGQTTAVGIGGDPVNGTNFIDALEAFNNDPETLAVVMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
PGKRMGHAGAIISGGKGTAEEKIKTMNACGIKTAATPSEIGSTLIERIKEEDGLYDKCLTVK

Sequences:

>Translated_302_residues
MGVFIDKDTKVIVQGITGSTALFHTKQMIEYGTKIVAGVTPGKGGMEVEGVPVFNTVEEAVKATGATVSVIYVPAPFAAD
AIVECVDAELDLAICITEHIPVLDMVKVKRYMQGKKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYE
AVHQLTQAGIGQTTAVGIGGDPVNGTNFIDALEAFNNDPETLAVVMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
PGKRMGHAGAIISGGKGTAEEKIKTMNACGIKTAATPSEIGSTLIERIKEEDGLYDKCLTVK
>Mature_301_residues
GVFIDKDTKVIVQGITGSTALFHTKQMIEYGTKIVAGVTPGKGGMEVEGVPVFNTVEEAVKATGATVSVIYVPAPFAADA
IVECVDAELDLAICITEHIPVLDMVKVKRYMQGKKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEA
VHQLTQAGIGQTTAVGIGGDPVNGTNFIDALEAFNNDPETLAVVMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAPP
GKRMGHAGAIISGGKGTAEEKIKTMNACGIKTAATPSEIGSTLIERIKEEDGLYDKCLTVK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=297, Percent_Identity=59.5959595959596, Blast_Score=309, Evalue=2e-84,
Organism=Homo sapiens, GI38569423, Length=255, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI38569421, Length=255, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=64.0138408304498, Blast_Score=367, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17550194, Length=285, Percent_Identity=62.1052631578947, Blast_Score=338, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17553126, Length=284, Percent_Identity=58.4507042253521, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17557344, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551266, Length=254, Percent_Identity=24.4094488188976, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324716, Length=295, Percent_Identity=47.1186440677966, Blast_Score=257, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21356559, Length=289, Percent_Identity=56.7474048442907, Blast_Score=333, Evalue=8e-92,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=56.3573883161512, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI281363477, Length=296, Percent_Identity=26.3513513513513, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281363475, Length=296, Percent_Identity=26.3513513513513, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281363473, Length=296, Percent_Identity=26.3513513513513, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31529; Mature: 31398

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVFIDKDTKVIVQGITGSTALFHTKQMIEYGTKIVAGVTPGKGGMEVEGVPVFNTVEEA
CCEEECCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCCEEECCCCCHHHHHHH
VKATGATVSVIYVPAPFAADAIVECVDAELDLAICITEHIPVLDMVKVKRYMQGKKTRLV
HHHCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTQAGIGQTTAVGIGG
CCCCCCEEEECCCEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCC
DPVNGTNFIDALEAFNNDPETLAVVMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
CCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
PGKRMGHAGAIISGGKGTAEEKIKTMNACGIKTAATPSEIGSTLIERIKEEDGLYDKCLT
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHEEE
VK
CC
>Mature Secondary Structure 
GVFIDKDTKVIVQGITGSTALFHTKQMIEYGTKIVAGVTPGKGGMEVEGVPVFNTVEEA
CEEECCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCCEEECCCCCHHHHHHH
VKATGATVSVIYVPAPFAADAIVECVDAELDLAICITEHIPVLDMVKVKRYMQGKKTRLV
HHHCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTQAGIGQTTAVGIGG
CCCCCCEEEECCCEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCC
DPVNGTNFIDALEAFNNDPETLAVVMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
CCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
PGKRMGHAGAIISGGKGTAEEKIKTMNACGIKTAATPSEIGSTLIERIKEEDGLYDKCLT
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHEEE
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA