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The map label for this gene is recG [H]

Identifier: 222151060

GI number: 222151060

Start: 881788

End: 883824

Strand: Direct

Name: recG [H]

Synonym: MCCL_0811

Alternate gene names: 222151060

Gene position: 881788-883824 (Clockwise)

Preceding gene: 222151059

Following gene: 222151061

Centisome position: 41.94

GC content: 40.06

Gene sequence:

>2037_bases
TTGGAAAATCAGCATCTTCTAATAACAGATAGTACATTGAAGGAGTTAAAAGGTGTCGGTCCGAAATCTTTAGAGAGTCT
CAATTCACTCAACATACATTCTATTGAAGATCTCATATTATATCTGCCTTATAAATATGAAGATGAAACCGTCATTAATT
TACATGAAGCCGAAGATGGTGCAAAAATAACGGTGCAGGGTGAAATTTACTCTGCGCCTGTTTTGGCTCATTTTGGTCGC
GGAAAATCTAAAGTATCATTCCATATGATGGTTGACAATGTCGCGGTGAAAATAGAATTCTTTAATCAGATGTACGTGAA
ACGGATTGCAGAAATAGGCAAGACGGTTAAAGTAACCGGTAAATGGAACAGGTCGAAACAGGTGATTCAAGGCAGTAAAA
TATCAGAAGATGAACATTCAGGTGTGCAGCTTGTCCCGCAATATAGTCTGAAAGGTTTGATTAAGCGCGCGCAGTTTAGA
AAGATGATTGACAGCGCGTTTCAGACCGTGAAAATTCAGCCCTTTTTGCCGGAACATTTAAAAGTGAGATATAAACTTTG
GGATCTGGATCAATCGCTATATGAGTTACATATTCCTTCAAGCCATAAACATCTGCAGCAGGCACGTAGAAGTTTTGCGT
TTTGTGAATTATTACTCTTTCAACTAAAGATGCGGATGCTTAATCAGCTTGAACAAAGCGGAGCGCCACATAGCAAGGTT
GATTATGATATCACGAAGGTTAAGGCGTTTATTGATACCCTGCCATTCGAATTGACAGAAGCACAGAAACAAGTGGTCAA
TGAAATATTTCGGGATATGAAGCATGAATTTCGCATGAATAGGCTGCTTCAAGGTGACGTAGGATCAGGGAAGACAATCG
TTGCTGCAATTTGCATGTATGCATTAATGACTGCAGGTAGACAAAGTGCATTGATGGTGCCTACTGAGATACTGGCTGAA
CAGCATGCAGAAAGTTTATCTGAAATCTATGGTGAATCACTAAACATAGCACTCCTTACAAGTTCCATCAAAGGTAAAAA
GCGGAGATTAATTTTAGAAGCGTTAGAACGTGGCGATATCGATATTATTGTAGGTACGCATGCGCTTATCAGTGAACCCG
TTCAATTTAATGATCTCGGTCTAGTCATTACTGATGAGCAGCATAGGTTTGGAGTAAATCAGCGTAAATTATTACGTGAA
AAAGGTAATGATGCAAATGTACTCTTTATGACAGCGACACCGATACCACGTACATTAGCAATCTCTGTATTTGGTGAACT
TGACGTTTCAACGATTAAACAGATGCCAAAAGGACGTAAACCCATTATTACAGAATGGGCGAAACATGAGGAAATTGAAA
TTGTGCATGACAAGACTGCACGTGAAATACGAGCGGGCCGACAAGTCTACGTAATATGTCCGCTGATTGAAGCTTCACAA
CATCTGGATGTAAAAAACGCGACTGAAATCTATGAAGCTTATCAAAGGCTATTTGGCACTGATAAAGTAGGATTACTTCA
TGGTAAGATGAAGACAGAAGAAAAAGATGAAGTGATGAATAAATTCCAAAATCATGACTTTGATGTTATAGTGTCTACAA
CAGTGGTTGAAGTCGGTGTGAATGTTCCGAACGCAACGATGATTGTCATCTATGATGCAGAACGTTTTGGTTTATCTACC
TTGCATCAGTTAAGAGGTCGTGTCGGTCGAAGTTCTTATCAAAGTTATTGTATATTGGTGGGCAATCCAGAAAGCGAAAC
AGGAATTGAAAGGTTGCAGATTATGACGCAGACAACAGATGGCTTTGTACTCAGTGAAAAGGATCTGGAAATGAGAGGGC
CGGGTGACTTCTTCGGCATTAAGCAAAGTGGTCTACCGGACTTTAAGGTAGCAAATATTGTTGAGGATTATCGCATGCTG
GAAGTCGCACGTGACGAAGCAAGCGAGCTAATACTAAGTGGTGCAATCGAACAACCTGAATTACGCGCATTAAAGATGCG
TCTAGATGCAGACCTTGCAGTACATCAACTTGACTAA

Upstream 100 bases:

>100_bases
ATGTATAAGATAGGTTTAACAATGCCAAGTGCACTGCGTGAGACAGGTCGTGGAGGTCTTGCAGGCACTAAGACTGGCCA
GGAAATGAAGGAAAGAATCT

Downstream 100 bases:

>100_bases
GAGGAGATTGAAATGAGAGTTATCGTAAGATTGATGGGAGTTCTATGTATCATAGCAGCGATTACGATGTTTTTCTGGCA
GGATATTCGTGCGTATTTCA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MENQHLLITDSTLKELKGVGPKSLESLNSLNIHSIEDLILYLPYKYEDETVINLHEAEDGAKITVQGEIYSAPVLAHFGR
GKSKVSFHMMVDNVAVKIEFFNQMYVKRIAEIGKTVKVTGKWNRSKQVIQGSKISEDEHSGVQLVPQYSLKGLIKRAQFR
KMIDSAFQTVKIQPFLPEHLKVRYKLWDLDQSLYELHIPSSHKHLQQARRSFAFCELLLFQLKMRMLNQLEQSGAPHSKV
DYDITKVKAFIDTLPFELTEAQKQVVNEIFRDMKHEFRMNRLLQGDVGSGKTIVAAICMYALMTAGRQSALMVPTEILAE
QHAESLSEIYGESLNIALLTSSIKGKKRRLILEALERGDIDIIVGTHALISEPVQFNDLGLVITDEQHRFGVNQRKLLRE
KGNDANVLFMTATPIPRTLAISVFGELDVSTIKQMPKGRKPIITEWAKHEEIEIVHDKTAREIRAGRQVYVICPLIEASQ
HLDVKNATEIYEAYQRLFGTDKVGLLHGKMKTEEKDEVMNKFQNHDFDVIVSTTVVEVGVNVPNATMIVIYDAERFGLST
LHQLRGRVGRSSYQSYCILVGNPESETGIERLQIMTQTTDGFVLSEKDLEMRGPGDFFGIKQSGLPDFKVANIVEDYRML
EVARDEASELILSGAIEQPELRALKMRLDADLAVHQLD

Sequences:

>Translated_678_residues
MENQHLLITDSTLKELKGVGPKSLESLNSLNIHSIEDLILYLPYKYEDETVINLHEAEDGAKITVQGEIYSAPVLAHFGR
GKSKVSFHMMVDNVAVKIEFFNQMYVKRIAEIGKTVKVTGKWNRSKQVIQGSKISEDEHSGVQLVPQYSLKGLIKRAQFR
KMIDSAFQTVKIQPFLPEHLKVRYKLWDLDQSLYELHIPSSHKHLQQARRSFAFCELLLFQLKMRMLNQLEQSGAPHSKV
DYDITKVKAFIDTLPFELTEAQKQVVNEIFRDMKHEFRMNRLLQGDVGSGKTIVAAICMYALMTAGRQSALMVPTEILAE
QHAESLSEIYGESLNIALLTSSIKGKKRRLILEALERGDIDIIVGTHALISEPVQFNDLGLVITDEQHRFGVNQRKLLRE
KGNDANVLFMTATPIPRTLAISVFGELDVSTIKQMPKGRKPIITEWAKHEEIEIVHDKTAREIRAGRQVYVICPLIEASQ
HLDVKNATEIYEAYQRLFGTDKVGLLHGKMKTEEKDEVMNKFQNHDFDVIVSTTVVEVGVNVPNATMIVIYDAERFGLST
LHQLRGRVGRSSYQSYCILVGNPESETGIERLQIMTQTTDGFVLSEKDLEMRGPGDFFGIKQSGLPDFKVANIVEDYRML
EVARDEASELILSGAIEQPELRALKMRLDADLAVHQLD
>Mature_678_residues
MENQHLLITDSTLKELKGVGPKSLESLNSLNIHSIEDLILYLPYKYEDETVINLHEAEDGAKITVQGEIYSAPVLAHFGR
GKSKVSFHMMVDNVAVKIEFFNQMYVKRIAEIGKTVKVTGKWNRSKQVIQGSKISEDEHSGVQLVPQYSLKGLIKRAQFR
KMIDSAFQTVKIQPFLPEHLKVRYKLWDLDQSLYELHIPSSHKHLQQARRSFAFCELLLFQLKMRMLNQLEQSGAPHSKV
DYDITKVKAFIDTLPFELTEAQKQVVNEIFRDMKHEFRMNRLLQGDVGSGKTIVAAICMYALMTAGRQSALMVPTEILAE
QHAESLSEIYGESLNIALLTSSIKGKKRRLILEALERGDIDIIVGTHALISEPVQFNDLGLVITDEQHRFGVNQRKLLRE
KGNDANVLFMTATPIPRTLAISVFGELDVSTIKQMPKGRKPIITEWAKHEEIEIVHDKTAREIRAGRQVYVICPLIEASQ
HLDVKNATEIYEAYQRLFGTDKVGLLHGKMKTEEKDEVMNKFQNHDFDVIVSTTVVEVGVNVPNATMIVIYDAERFGLST
LHQLRGRVGRSSYQSYCILVGNPESETGIERLQIMTQTTDGFVLSEKDLEMRGPGDFFGIKQSGLPDFKVANIVEDYRML
EVARDEASELILSGAIEQPELRALKMRLDADLAVHQLD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=672, Percent_Identity=38.6904761904762, Blast_Score=400, Evalue=1e-112,
Organism=Escherichia coli, GI1787357, Length=390, Percent_Identity=36.6666666666667, Blast_Score=260, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76816; Mature: 76816

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQHLLITDSTLKELKGVGPKSLESLNSLNIHSIEDLILYLPYKYEDETVINLHEAEDG
CCCCEEEEECHHHHHHHCCCHHHHHHHCCCCCCCHHHHHEECCCCCCCCEEEEEEECCCC
AKITVQGEIYSAPVLAHFGRGKSKVSFHMMVDNVAVKIEFFNQMYVKRIAEIGKTVKVTG
CEEEEECCEECCCHHHHCCCCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHCCCEEEEEE
KWNRSKQVIQGSKISEDEHSGVQLVPQYSLKGLIKRAQFRKMIDSAFQTVKIQPFLPEHL
CCCCCHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHH
KVRYKLWDLDQSLYELHIPSSHKHLQQARRSFAFCELLLFQLKMRMLNQLEQSGAPHSKV
EEEEEEECCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DYDITKVKAFIDTLPFELTEAQKQVVNEIFRDMKHEFRMNRLLQGDVGSGKTIVAAICMY
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ALMTAGRQSALMVPTEILAEQHAESLSEIYGESLNIALLTSSIKGKKRRLILEALERGDI
HHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCE
DIIVGTHALISEPVQFNDLGLVITDEQHRFGVNQRKLLREKGNDANVLFMTATPIPRTLA
EEEEECHHHHCCCCEECCEEEEEECCHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCEEE
ISVFGELDVSTIKQMPKGRKPIITEWAKHEEIEIVHDKTAREIRAGRQVYVICPLIEASQ
EEEECCCCHHHHHHCCCCCCCCHHHHCCCCCEEEEECHHHHHHHCCCEEEEEEEECCCCC
HLDVKNATEIYEAYQRLFGTDKVGLLHGKMKTEEKDEVMNKFQNHDFDVIVSTTVVEVGV
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEEEECC
NVPNATMIVIYDAERFGLSTLHQLRGRVGRSSYQSYCILVGNPESETGIERLQIMTQTTD
CCCCCEEEEEECCHHCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHEEEEECCC
GFVLSEKDLEMRGPGDFFGIKQSGLPDFKVANIVEDYRMLEVARDEASELILSGAIEQPE
CEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LRALKMRLDADLAVHQLD
HHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MENQHLLITDSTLKELKGVGPKSLESLNSLNIHSIEDLILYLPYKYEDETVINLHEAEDG
CCCCEEEEECHHHHHHHCCCHHHHHHHCCCCCCCHHHHHEECCCCCCCCEEEEEEECCCC
AKITVQGEIYSAPVLAHFGRGKSKVSFHMMVDNVAVKIEFFNQMYVKRIAEIGKTVKVTG
CEEEEECCEECCCHHHHCCCCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHCCCEEEEEE
KWNRSKQVIQGSKISEDEHSGVQLVPQYSLKGLIKRAQFRKMIDSAFQTVKIQPFLPEHL
CCCCCHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHH
KVRYKLWDLDQSLYELHIPSSHKHLQQARRSFAFCELLLFQLKMRMLNQLEQSGAPHSKV
EEEEEEECCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DYDITKVKAFIDTLPFELTEAQKQVVNEIFRDMKHEFRMNRLLQGDVGSGKTIVAAICMY
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ALMTAGRQSALMVPTEILAEQHAESLSEIYGESLNIALLTSSIKGKKRRLILEALERGDI
HHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCE
DIIVGTHALISEPVQFNDLGLVITDEQHRFGVNQRKLLREKGNDANVLFMTATPIPRTLA
EEEEECHHHHCCCCEECCEEEEEECCHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCEEE
ISVFGELDVSTIKQMPKGRKPIITEWAKHEEIEIVHDKTAREIRAGRQVYVICPLIEASQ
EEEECCCCHHHHHHCCCCCCCCHHHHCCCCCEEEEECHHHHHHHCCCEEEEEEEECCCCC
HLDVKNATEIYEAYQRLFGTDKVGLLHGKMKTEEKDEVMNKFQNHDFDVIVSTTVVEVGV
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEEEECC
NVPNATMIVIYDAERFGLSTLHQLRGRVGRSSYQSYCILVGNPESETGIERLQIMTQTTD
CCCCCEEEEEECCHHCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHEEEEECCC
GFVLSEKDLEMRGPGDFFGIKQSGLPDFKVANIVEDYRMLEVARDEASELILSGAIEQPE
CEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LRALKMRLDADLAVHQLD
HHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9257758 [H]