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The map label for this gene is pyrAA [H]

Identifier: 222151021

GI number: 222151021

Start: 831424

End: 832518

Strand: Direct

Name: pyrAA [H]

Synonym: MCCL_0772

Alternate gene names: 222151021

Gene position: 831424-832518 (Clockwise)

Preceding gene: 222151020

Following gene: 222151022

Centisome position: 39.55

GC content: 40.91

Gene sequence:

>1095_bases
ATGCGTAAACAAAGATATCTTGTATTAGAAGATGGCACTACATTTAAAGGATATAGATTTGGAAGTGACAAAGAGGTAGT
AGGGGAAATCGTATTTAATACTGCGATGACAGGTTATCAGGAGACATTATCTGATCCGTCATATACAGGACAAATCATTA
CATTCACTTATCCGTTGATCGGAAACTACGGGATTAACCGTGATGACTTCGAAACGTTAAACCCTTCTCTTAAAGGTATG
GTTGTTCGTGAAGCTTGTGATTTGCCGAGTAACTTTCGTAATATGGCGACACTCGATGAAACGTTAGAAAGCTATGACGT
TCCGGGGATCGACGGTGTAGATACTAGAAAATTAACACGTATAATTCGTCAGCACGGCGTATTGAAAGCAGCCCTTATCA
ATGATGAAAAGGATATTGATGCAACAATTGAACGTTTAAAAGAAGAAACGCTACCTACAGATGAAGTCGCACAAGTATCA
ACGAAGAGTGCATATGTGTCTACAGGTAACGATCTGCGTGTCGTGCTTATCGACTTCGGTAAGAAAGAAAACATTGTCCG
TGAACTGAACTCACGTGGCTGTGACGTAACAGTAATGCCATATACGACAACAGCTGAGGAGATTATCAGGCTGAGACCGG
ACGGTGTGATGTTATCCAATGGACCAGGGAATCCAGAAGTTGTAACTGAAGGAATCGAAATGATAAAAGGAATATTAGGA
AAAGTACCGTTCTTTGGTATATGTCTAGGACATCAGCTGTTCGCACTCGCAAGTGGTGCAACGACATTCAAGATGAAGTT
TGGACATCGTGGAGCAAACCATCCAGTGAAAAACTTAGCAACAGGTAAGATTGAAATCACATCTCAGAATCATGGTTACG
CAGTGGATCCGGAATCAATCAAAAACACGGACCTTGAAATTACACATACAGCTTTAAACGATGGAACAGTAGAAGGGCTG
AAGCATAAATCATTACCTGCATTCTCGGTGCAGTATCATCCGGAAGCGTCACCAGGTCCTCATGATCCAAACTATTTATT
TGATCAGTTTATCGACTTAATGAAAGAAAATAAGGAGCGTGTCACAAATGCCTAA

Upstream 100 bases:

>100_bases
TTATCAAAATCAAGTAATACACCATTTATTGGAGAACATGTCTACGGCAATGTGAAGCTAACACTTGTAGAAGGACAAAT
CGCTTATCAGGAGGGGCAAC

Downstream 100 bases:

>100_bases
ACGTAATGATATTAAAACAATTCTCGTAATCGGTTCAGGTCCAATTATTATTGGACAAGCTGCAGAGTTTGACTATGCAG
GTACTCAAGCATGTCTGGCA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRKQRYLVLEDGTTFKGYRFGSDKEVVGEIVFNTAMTGYQETLSDPSYTGQIITFTYPLIGNYGINRDDFETLNPSLKGM
VVREACDLPSNFRNMATLDETLESYDVPGIDGVDTRKLTRIIRQHGVLKAALINDEKDIDATIERLKEETLPTDEVAQVS
TKSAYVSTGNDLRVVLIDFGKKENIVRELNSRGCDVTVMPYTTTAEEIIRLRPDGVMLSNGPGNPEVVTEGIEMIKGILG
KVPFFGICLGHQLFALASGATTFKMKFGHRGANHPVKNLATGKIEITSQNHGYAVDPESIKNTDLEITHTALNDGTVEGL
KHKSLPAFSVQYHPEASPGPHDPNYLFDQFIDLMKENKERVTNA

Sequences:

>Translated_364_residues
MRKQRYLVLEDGTTFKGYRFGSDKEVVGEIVFNTAMTGYQETLSDPSYTGQIITFTYPLIGNYGINRDDFETLNPSLKGM
VVREACDLPSNFRNMATLDETLESYDVPGIDGVDTRKLTRIIRQHGVLKAALINDEKDIDATIERLKEETLPTDEVAQVS
TKSAYVSTGNDLRVVLIDFGKKENIVRELNSRGCDVTVMPYTTTAEEIIRLRPDGVMLSNGPGNPEVVTEGIEMIKGILG
KVPFFGICLGHQLFALASGATTFKMKFGHRGANHPVKNLATGKIEITSQNHGYAVDPESIKNTDLEITHTALNDGTVEGL
KHKSLPAFSVQYHPEASPGPHDPNYLFDQFIDLMKENKERVTNA
>Mature_364_residues
MRKQRYLVLEDGTTFKGYRFGSDKEVVGEIVFNTAMTGYQETLSDPSYTGQIITFTYPLIGNYGINRDDFETLNPSLKGM
VVREACDLPSNFRNMATLDETLESYDVPGIDGVDTRKLTRIIRQHGVLKAALINDEKDIDATIERLKEETLPTDEVAQVS
TKSAYVSTGNDLRVVLIDFGKKENIVRELNSRGCDVTVMPYTTTAEEIIRLRPDGVMLSNGPGNPEVVTEGIEMIKGILG
KVPFFGICLGHQLFALASGATTFKMKFGHRGANHPVKNLATGKIEITSQNHGYAVDPESIKNTDLEITHTALNDGTVEGL
KHKSLPAFSVQYHPEASPGPHDPNYLFDQFIDLMKENKERVTNA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=363, Percent_Identity=41.8732782369146, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI21361331, Length=370, Percent_Identity=38.1081081081081, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI169790915, Length=370, Percent_Identity=38.1081081081081, Blast_Score=239, Evalue=4e-63,
Organism=Escherichia coli, GI1786215, Length=381, Percent_Identity=45.4068241469816, Blast_Score=328, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI193204318, Length=372, Percent_Identity=40.8602150537634, Blast_Score=268, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6324878, Length=365, Percent_Identity=41.6438356164384, Blast_Score=272, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6322331, Length=394, Percent_Identity=39.3401015228426, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6322638, Length=178, Percent_Identity=32.5842696629214, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45555749, Length=381, Percent_Identity=39.3700787401575, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24642586, Length=381, Percent_Identity=39.3700787401575, Blast_Score=260, Evalue=8e-70,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40338; Mature: 40338

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKQRYLVLEDGTTFKGYRFGSDKEVVGEIVFNTAMTGYQETLSDPSYTGQIITFTYPLI
CCCCEEEEEECCCEECCEEECCCHHHHHHHHHHHHHHCHHHHHCCCCCCCEEEEEEEEEC
GNYGINRDDFETLNPSLKGMVVREACDLPSNFRNMATLDETLESYDVPGIDGVDTRKLTR
CCCCCCCCCHHHCCCCHHHEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
IIRQHGVLKAALINDEKDIDATIERLKEETLPTDEVAQVSTKSAYVSTGNDLRVVLIDFG
HHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCEEEEEEECC
KKENIVRELNSRGCDVTVMPYTTTAEEIIRLRPDGVMLSNGPGNPEVVTEGIEMIKGILG
CCHHHHHHHHCCCCEEEEEECCCCHHHHHEECCCCEEEECCCCCHHHHHHHHHHHHHHHH
KVPFFGICLGHQLFALASGATTFKMKFGHRGANHPVKNLATGKIEITSQNHGYAVDPESI
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCEEEEEECCCCEEECHHHH
KNTDLEITHTALNDGTVEGLKHKSLPAFSVQYHPEASPGPHDPNYLFDQFIDLMKENKER
CCCCEEEEEEECCCCCHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
VTNA
HCCC
>Mature Secondary Structure
MRKQRYLVLEDGTTFKGYRFGSDKEVVGEIVFNTAMTGYQETLSDPSYTGQIITFTYPLI
CCCCEEEEEECCCEECCEEECCCHHHHHHHHHHHHHHCHHHHHCCCCCCCEEEEEEEEEC
GNYGINRDDFETLNPSLKGMVVREACDLPSNFRNMATLDETLESYDVPGIDGVDTRKLTR
CCCCCCCCCHHHCCCCHHHEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
IIRQHGVLKAALINDEKDIDATIERLKEETLPTDEVAQVSTKSAYVSTGNDLRVVLIDFG
HHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCEEEEEEECC
KKENIVRELNSRGCDVTVMPYTTTAEEIIRLRPDGVMLSNGPGNPEVVTEGIEMIKGILG
CCHHHHHHHHCCCCEEEEEECCCCHHHHHEECCCCEEEECCCCCHHHHHHHHHHHHHHHH
KVPFFGICLGHQLFALASGATTFKMKFGHRGANHPVKNLATGKIEITSQNHGYAVDPESI
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCEEEEEECCCCEEECHHHH
KNTDLEITHTALNDGTVEGLKHKSLPAFSVQYHPEASPGPHDPNYLFDQFIDLMKENKER
CCCCEEEEEEECCCCCHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
VTNA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA