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The map label for this gene is hmp [H]

Identifier: 222150934

GI number: 222150934

Start: 736435

End: 737577

Strand: Direct

Name: hmp [H]

Synonym: MCCL_0684

Alternate gene names: 222150934

Gene position: 736435-737577 (Clockwise)

Preceding gene: 222150932

Following gene: 222150935

Centisome position: 35.03

GC content: 42.96

Gene sequence:

>1143_bases
GTGTTAACAGAAGAAACTAAGAATATCGTCAAAGCGACGATTCCAGTGCTGGAGGAACATGGTACGGAGATTACTTCAGC
ATTCTATAAGCATATGTTCGAAGAGCATCCAGAATTACTGAATGTATTTAATAAGACGAACCAGAAGTTAGGGCGTCAAC
AGACAGCTTTAGCGCAGACGGTTATCGCTGCTGCTAAGCATATCGATCATCTGGAGGCGATTGTTCCGAACGTCAACCAG
ATCGCGCATAAACATAGAGCGTTAGAGATCAAACCGGAGCATTATCCGATTGTAGGTGAGAACTTGATCTGGGCGATTCA
GCATGTACTAGGTGATGCGGCAACGCCTGAGATTGTGGAGGCCTGGACAGAGACCTATGGTGTGATTGCTGATGTGTTTA
TTCAGATGGAGGCGACACTGTATGATGAAGCTGACTGGCAGGGCTTTGTACCGTTCAAGGTTGTAGCGGTTAAGGAAGAG
TCCCCGGACATTAAATCATTTACTGTTCAAAGTGATGCGATTCAATTGAAGCCTGTTAAAGCGGGTCAGTATATCACAGT
GAAGGTGCATCCTGAAGATGAAACAAATGATGCATTACGTCATTATTCAATCTGTTCTGTTGATACATCTCGTGGACTTA
AGTTCGCGGTTAAGCGTGACGTTGCAGGTGAAGAGAAAGGGATGGTCTCTAACTATCTACATGATCATGTGACAGCAGGA
GATGAGCTTCTGTTATCTGCACCGGCAGGTGAGTTCTTAGTTGAGACTGATAATAAGGACCTCGTATTTATAAGTGGGGG
CGTAGGTATGACGCCACTCATGAGTATGTTAGAGGATGAGGTGGAGAAACGACATATCAAGTTTATCCATTCAGCATATA
ACCGCGATGCTGTTCCATTTAAAGATGAGATTACGAAGTTCCATAATAATAGTAACGTAGAGTTCTTCTTTAACTATTCG
GAAAGTGAAGGTCGCTTAACGAAAGAGAAGTTATCTAAAATTATGAACGGTAACGAAGAAATCTATATGTGTGGTTCTGT
AGGATTTATGGAAGGCATGCTTGAGATTTTCAGTGATATGGGGATTGATCGAAGCCGTGTACACTTCGAGCCGTTTGGTC
CGAAGATGAGTATTACAGTATAA

Upstream 100 bases:

>100_bases
AATTTTTTGTTCATAGATGATATAAATGATTGTAATTTGTAGGGATGAGGTGTATATTAAAGATGTATTTATAATGTATC
TTTAAATAGGGGGAGTTAGT

Downstream 100 bases:

>100_bases
TAGCTGGTTTAGAGAACTATTAAAGCACAGCCTTAGCTGTGCTTTTTTTATTACGATATTTTAATTTCTGCATGAATTTC
ATGCAGTTTTTTAATATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLTEETKNIVKATIPVLEEHGTEITSAFYKHMFEEHPELLNVFNKTNQKLGRQQTALAQTVIAAAKHIDHLEAIVPNVNQ
IAHKHRALEIKPEHYPIVGENLIWAIQHVLGDAATPEIVEAWTETYGVIADVFIQMEATLYDEADWQGFVPFKVVAVKEE
SPDIKSFTVQSDAIQLKPVKAGQYITVKVHPEDETNDALRHYSICSVDTSRGLKFAVKRDVAGEEKGMVSNYLHDHVTAG
DELLLSAPAGEFLVETDNKDLVFISGGVGMTPLMSMLEDEVEKRHIKFIHSAYNRDAVPFKDEITKFHNNSNVEFFFNYS
ESEGRLTKEKLSKIMNGNEEIYMCGSVGFMEGMLEIFSDMGIDRSRVHFEPFGPKMSITV

Sequences:

>Translated_380_residues
MLTEETKNIVKATIPVLEEHGTEITSAFYKHMFEEHPELLNVFNKTNQKLGRQQTALAQTVIAAAKHIDHLEAIVPNVNQ
IAHKHRALEIKPEHYPIVGENLIWAIQHVLGDAATPEIVEAWTETYGVIADVFIQMEATLYDEADWQGFVPFKVVAVKEE
SPDIKSFTVQSDAIQLKPVKAGQYITVKVHPEDETNDALRHYSICSVDTSRGLKFAVKRDVAGEEKGMVSNYLHDHVTAG
DELLLSAPAGEFLVETDNKDLVFISGGVGMTPLMSMLEDEVEKRHIKFIHSAYNRDAVPFKDEITKFHNNSNVEFFFNYS
ESEGRLTKEKLSKIMNGNEEIYMCGSVGFMEGMLEIFSDMGIDRSRVHFEPFGPKMSITV
>Mature_380_residues
MLTEETKNIVKATIPVLEEHGTEITSAFYKHMFEEHPELLNVFNKTNQKLGRQQTALAQTVIAAAKHIDHLEAIVPNVNQ
IAHKHRALEIKPEHYPIVGENLIWAIQHVLGDAATPEIVEAWTETYGVIADVFIQMEATLYDEADWQGFVPFKVVAVKEE
SPDIKSFTVQSDAIQLKPVKAGQYITVKVHPEDETNDALRHYSICSVDTSRGLKFAVKRDVAGEEKGMVSNYLHDHVTAG
DELLLSAPAGEFLVETDNKDLVFISGGVGMTPLMSMLEDEVEKRHIKFIHSAYNRDAVPFKDEITKFHNNSNVEFFFNYS
ESEGRLTKEKLSKIMNGNEEIYMCGSVGFMEGMLEIFSDMGIDRSRVHFEPFGPKMSITV

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=398, Percent_Identity=35.929648241206, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1787098, Length=219, Percent_Identity=28.310502283105, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788104, Length=234, Percent_Identity=26.4957264957265, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321673, Length=395, Percent_Identity=47.8481012658228, Blast_Score=342, Evalue=6e-95,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR001834
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 42800; Mature: 42800

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTEETKNIVKATIPVLEEHGTEITSAFYKHMFEEHPELLNVFNKTNQKLGRQQTALAQT
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
VIAAAKHIDHLEAIVPNVNQIAHKHRALEIKPEHYPIVGENLIWAIQHVLGDAATPEIVE
HHHHHHHHHHHHHHCCCHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHH
AWTETYGVIADVFIQMEATLYDEADWQGFVPFKVVAVKEESPDIKSFTVQSDAIQLKPVK
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCCCCCEEEEECCCEEEEEEC
AGQYITVKVHPEDETNDALRHYSICSVDTSRGLKFAVKRDVAGEEKGMVSNYLHDHVTAG
CCCEEEEEECCCCCCCHHHHHEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCC
DELLLSAPAGEFLVETDNKDLVFISGGVGMTPLMSMLEDEVEKRHIKFIHSAYNRDAVPF
CCEEEECCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KDEITKFHNNSNVEFFFNYSESEGRLTKEKLSKIMNGNEEIYMCGSVGFMEGMLEIFSDM
HHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHC
GIDRSRVHFEPFGPKMSITV
CCCCCEEEECCCCCEEEEEC
>Mature Secondary Structure
MLTEETKNIVKATIPVLEEHGTEITSAFYKHMFEEHPELLNVFNKTNQKLGRQQTALAQT
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
VIAAAKHIDHLEAIVPNVNQIAHKHRALEIKPEHYPIVGENLIWAIQHVLGDAATPEIVE
HHHHHHHHHHHHHHCCCHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHH
AWTETYGVIADVFIQMEATLYDEADWQGFVPFKVVAVKEESPDIKSFTVQSDAIQLKPVK
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCCCCCEEEEECCCEEEEEEC
AGQYITVKVHPEDETNDALRHYSICSVDTSRGLKFAVKRDVAGEEKGMVSNYLHDHVTAG
CCCEEEEEECCCCCCCHHHHHEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCC
DELLLSAPAGEFLVETDNKDLVFISGGVGMTPLMSMLEDEVEKRHIKFIHSAYNRDAVPF
CCEEEECCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KDEITKFHNNSNVEFFFNYSESEGRLTKEKLSKIMNGNEEIYMCGSVGFMEGMLEIFSDM
HHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHC
GIDRSRVHFEPFGPKMSITV
CCCCCEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10484179; 11058132 [H]