Click here to switch to the map view.

The map label for this gene is nagD [H]

Identifier: 222150809

GI number: 222150809

Start: 595789

End: 596574

Strand: Direct

Name: nagD [H]

Synonym: MCCL_0559

Alternate gene names: 222150809

Gene position: 595789-596574 (Clockwise)

Preceding gene: 222150808

Following gene: 222150810

Centisome position: 28.34

GC content: 38.55

Gene sequence:

>786_bases
TTGAAGAAGTATAAAGGTTATCTGTTAGATTTAGATGGAACGATGTACGCTGGCACACGCGTGATAGAAGGTGCAAAGGA
ATTTATCGAATATTTGTCGAATAATAATCTGCCCTACCTCTTTGTTACAAATAACGCATCGAAACGTCCAGATGAAGTTG
CTGAGAAATTAACGAATATGGGATTTATTGCAACGGCTGATAATGTTGTCACAAGTGCAATGGCAACAGCAAGTTATATC
GCAGAAGAACATCCAGGTGCAAGTGTCTATGTCATTGGTGGTACTGGAATCAGACAAGCCTTACAAGATGAACAGCTTGT
TATAACTGATGATATTCATGTGGATTATGTCGTTATTGGACTAGATGTAGACATCAACTATGAAAAATTATCTAAAGCAT
GTCTTGCTGTGCGTAATGGGGCTCGATTTATTTCGACAAATCCAGATACGTCTATTCCGACAGAACGTGGATTTTTACCT
GGGAATGGAGCTTTGACGAGTGTGGTCTCTGTATCAACGGGTATAGCACCTAAGTTTATCGGTAAACCAATGGAAACGAT
TATGAATAAAGCAGTTGATATGATGCAATTACCGAAAGAAGAACTTGTAATGATCGGTGATTTGTATATGACAGACATTA
TGAGCGGTATCAATGCAGGGATAGATACATTACATGTTCAAACAGGGGTCAGTACTTATGAACAGGTGATGGCAGAGCAA
GTTCCACCGACGCATAGTGTTAAAAACTTATTAGATGTTATTCGCATATACGAAAATGGTGAATAA

Upstream 100 bases:

>100_bases
ATGGAGAATATCGCAAGCTATAAACAGTTTAAAGCAAATGTGGATGCATTTATTGAAAATGAATTAGGACCAGTATCAGC
ATTTGGAAAGGGTGGAAAAG

Downstream 100 bases:

>100_bases
TATGCGTGAGTTGATCATCAAAAAATTGAAAGCAGCAGCATGAAAAATACTATGAGAAATCATAGTATTTTTTTGTGTCC
AAATTATGAACAGGAAATTT

Product: haloacid dehalogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKKYKGYLLDLDGTMYAGTRVIEGAKEFIEYLSNNNLPYLFVTNNASKRPDEVAEKLTNMGFIATADNVVTSAMATASYI
AEEHPGASVYVIGGTGIRQALQDEQLVITDDIHVDYVVIGLDVDINYEKLSKACLAVRNGARFISTNPDTSIPTERGFLP
GNGALTSVVSVSTGIAPKFIGKPMETIMNKAVDMMQLPKEELVMIGDLYMTDIMSGINAGIDTLHVQTGVSTYEQVMAEQ
VPPTHSVKNLLDVIRIYENGE

Sequences:

>Translated_261_residues
MKKYKGYLLDLDGTMYAGTRVIEGAKEFIEYLSNNNLPYLFVTNNASKRPDEVAEKLTNMGFIATADNVVTSAMATASYI
AEEHPGASVYVIGGTGIRQALQDEQLVITDDIHVDYVVIGLDVDINYEKLSKACLAVRNGARFISTNPDTSIPTERGFLP
GNGALTSVVSVSTGIAPKFIGKPMETIMNKAVDMMQLPKEELVMIGDLYMTDIMSGINAGIDTLHVQTGVSTYEQVMAEQ
VPPTHSVKNLLDVIRIYENGE
>Mature_261_residues
MKKYKGYLLDLDGTMYAGTRVIEGAKEFIEYLSNNNLPYLFVTNNASKRPDEVAEKLTNMGFIATADNVVTSAMATASYI
AEEHPGASVYVIGGTGIRQALQDEQLVITDDIHVDYVVIGLDVDINYEKLSKACLAVRNGARFISTNPDTSIPTERGFLP
GNGALTSVVSVSTGIAPKFIGKPMETIMNKAVDMMQLPKEELVMIGDLYMTDIMSGINAGIDTLHVQTGVSTYEQVMAEQ
VPPTHSVKNLLDVIRIYENGE

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=254, Percent_Identity=28.740157480315, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI108796653, Length=273, Percent_Identity=30.03663003663, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI14149777, Length=243, Percent_Identity=25.5144032921811, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786890, Length=240, Percent_Identity=33.75, Blast_Score=141, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17558880, Length=270, Percent_Identity=27.037037037037, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562458, Length=270, Percent_Identity=27.037037037037, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560956, Length=270, Percent_Identity=27.037037037037, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193210059, Length=261, Percent_Identity=27.9693486590038, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI86563050, Length=245, Percent_Identity=27.7551020408163, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319965, Length=240, Percent_Identity=26.25, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24666141, Length=254, Percent_Identity=25.9842519685039, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24656330, Length=258, Percent_Identity=26.7441860465116, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24656326, Length=262, Percent_Identity=25.5725190839695, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19920940, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI22026920, Length=235, Percent_Identity=23.4042553191489, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641437, Length=247, Percent_Identity=25.5060728744939, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 28438; Mature: 28438

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYKGYLLDLDGTMYAGTRVIEGAKEFIEYLSNNNLPYLFVTNNASKRPDEVAEKLTNM
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCC
GFIATADNVVTSAMATASYIAEEHPGASVYVIGGTGIRQALQDEQLVITDDIHVDYVVIG
CEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCEEEEECCEEEEEEEE
LDVDINYEKLSKACLAVRNGARFISTNPDTSIPTERGFLPGNGALTSVVSVSTGIAPKFI
EEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
GKPMETIMNKAVDMMQLPKEELVMIGDLYMTDIMSGINAGIDTLHVQTGVSTYEQVMAEQ
CCHHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
VPPTHSVKNLLDVIRIYENGE
CCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKYKGYLLDLDGTMYAGTRVIEGAKEFIEYLSNNNLPYLFVTNNASKRPDEVAEKLTNM
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCC
GFIATADNVVTSAMATASYIAEEHPGASVYVIGGTGIRQALQDEQLVITDDIHVDYVVIG
CEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCEEEEECCEEEEEEEE
LDVDINYEKLSKACLAVRNGARFISTNPDTSIPTERGFLPGNGALTSVVSVSTGIAPKFI
EEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
GKPMETIMNKAVDMMQLPKEELVMIGDLYMTDIMSGINAGIDTLHVQTGVSTYEQVMAEQ
CCHHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
VPPTHSVKNLLDVIRIYENGE
CCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA