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The map label for this gene is est [H]

Identifier: 222150777

GI number: 222150777

Start: 559785

End: 560525

Strand: Direct

Name: est [H]

Synonym: MCCL_0527

Alternate gene names: 222150777

Gene position: 559785-560525 (Clockwise)

Preceding gene: 222150776

Following gene: 222150778

Centisome position: 26.63

GC content: 38.46

Gene sequence:

>741_bases
ATGAAAATAAGATTACCAGAACCGTTCTTTTTTGAAGAGGGAAAAAGAGCAGTTTTATTATTACATGGGTTTACTGGGAA
TTCATCAGATGTGAGACAACTTGGACGATTCCTGCAGAAAAAAGGGTATACAAGTTATGCACCACACTATGAAGGTCATG
GAGTACCCCCAGAAGAACTGCTTGCATCTAGTCCTCATGTATGGTGGAGCCAAGTCCTAGAAGCTTATGATTTCTTAGTA
GAAAAAGGATATAATGAAATTGCAGTAGCAGGACTATCACTCGGTGGTGTCTTCGCTTTGAAGCTGGCGCAATATCGTGA
TGTGTTAGCTGTAGCTACAATGTGCAGCCCGATGTATATTAAGACGACTGGCAATATGTATGAGGGTGTCCTGGCGTATG
CAAGTGAGTTTAAGAAACGTGAAGGTAAATCAAAGGTACAAATTGATCGTGAAATGGAAGCTTTTCATCCGACAGATATG
CTTGTAGATTTACAAAAGACGATTCAAGATGTCCGAGATACAGTAGATAATGTATATGCGCCACTGTTTGTAGCTCAAGG
TAGACTGGATACGATGATTAATCCGGATTCGGCGAACATTATCTACAATGAAGCAGAAAGCGATGACAAAGAAATGCATT
GGTATGAACAAAGTGGTCACGTTATAACAATAGATAAAGAAAAAGAACAGTTATTTGAAGATTATTATCAGTTTTTAGAA
CAATTAGACTGGTCAAATTAA

Upstream 100 bases:

>100_bases
TTAACACAGGTCCGGACAATCGCGTTCGGGCTTTTTTATTTTAAATCTGTTCGCAAAAAACTTACAATAGTAGATGAGGA
TATTAAAAGGAGAATGTATT

Downstream 100 bases:

>100_bases
AGGAGGAATTATATGCATCTGTATGAACATGAAGTAATTGCATATTTAAAATCATTAAAGGGTAGTGCAGTTACGATAGA
AGCAATAGAAGCGCATCTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKIRLPEPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPHYEGHGVPPEELLASSPHVWWSQVLEAYDFLV
EKGYNEIAVAGLSLGGVFALKLAQYRDVLAVATMCSPMYIKTTGNMYEGVLAYASEFKKREGKSKVQIDREMEAFHPTDM
LVDLQKTIQDVRDTVDNVYAPLFVAQGRLDTMINPDSANIIYNEAESDDKEMHWYEQSGHVITIDKEKEQLFEDYYQFLE
QLDWSN

Sequences:

>Translated_246_residues
MKIRLPEPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPHYEGHGVPPEELLASSPHVWWSQVLEAYDFLV
EKGYNEIAVAGLSLGGVFALKLAQYRDVLAVATMCSPMYIKTTGNMYEGVLAYASEFKKREGKSKVQIDREMEAFHPTDM
LVDLQKTIQDVRDTVDNVYAPLFVAQGRLDTMINPDSANIIYNEAESDDKEMHWYEQSGHVITIDKEKEQLFEDYYQFLE
QLDWSN
>Mature_246_residues
MKIRLPEPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPHYEGHGVPPEELLASSPHVWWSQVLEAYDFLV
EKGYNEIAVAGLSLGGVFALKLAQYRDVLAVATMCSPMYIKTTGNMYEGVLAYASEFKKREGKSKVQIDREMEAFHPTDM
LVDLQKTIQDVRDTVDNVYAPLFVAQGRLDTMINPDSANIIYNEAESDDKEMHWYEQSGHVITIDKEKEQLFEDYYQFLE
QLDWSN

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012354
- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 28228; Mature: 28228

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRLPEPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPHYEGHGVPPEEL
CCCCCCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
LASSPHVWWSQVLEAYDFLVEKGYNEIAVAGLSLGGVFALKLAQYRDVLAVATMCSPMYI
HCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHCCCEEE
KTTGNMYEGVLAYASEFKKREGKSKVQIDREMEAFHPTDMLVDLQKTIQDVRDTVDNVYA
EECCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
PLFVAQGRLDTMINPDSANIIYNEAESDDKEMHWYEQSGHVITIDKEKEQLFEDYYQFLE
HHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHEECCCCEEEEECHHHHHHHHHHHHHH
QLDWSN
HCCCCC
>Mature Secondary Structure
MKIRLPEPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPHYEGHGVPPEEL
CCCCCCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
LASSPHVWWSQVLEAYDFLVEKGYNEIAVAGLSLGGVFALKLAQYRDVLAVATMCSPMYI
HCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHCCCEEE
KTTGNMYEGVLAYASEFKKREGKSKVQIDREMEAFHPTDMLVDLQKTIQDVRDTVDNVYA
EECCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
PLFVAQGRLDTMINPDSANIIYNEAESDDKEMHWYEQSGHVITIDKEKEQLFEDYYQFLE
HHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHEECCCCEEEEECHHHHHHHHHHHHHH
QLDWSN
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1369099 [H]