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The map label for this gene is trxB [H]

Identifier: 222150765

GI number: 222150765

Start: 547151

End: 548080

Strand: Direct

Name: trxB [H]

Synonym: MCCL_0515

Alternate gene names: 222150765

Gene position: 547151-548080 (Clockwise)

Preceding gene: 222150764

Following gene: 222150766

Centisome position: 26.03

GC content: 40.32

Gene sequence:

>930_bases
ATGAGTGAAATTAAAGAATATGACGTGATCATTGTTGGTGCTGGTCCAGCCGGGATGACAGCAGCAGTCTATGCATCTAG
AGCAAACCTATCTACGATTATGATTGAACGTGGTATGCCTGGTGGACAGATGGCCAATACTGCAGACGTCGAAAATTTTC
CTGGATTTGATCTGATCACAGGACCTGACCTTTCAACGAAGATGTTCTCCCATGCACAGAAATTCGGTGCAGAATATACT
TATGGTGATATTAAAAATATTACTGTTGAAGGCGATGACAAGATTGTAGATCTAGGTGACAAGCAGTTAAAAGCAAAAGC
AGTTATTATTGCGACAGGTGCAGAATATAAGAAGATTGGTGTGCCAGGAGAATCAGAGCTTGGTGGACGCGGCGTATCTT
ACTGTGCTGTGTGTGACGGTGCATTCTTCAAACAGAAGAACTTAGTAGTAATCGGTGGGGGAGATTCTGCAGTCGAAGAA
GGAGTATACTTAACGAAATATGCAGACAAAGTAACGATCGTGCATAGAAGAGATACATTAAGAGCTCAGAAAATTCTTCA
GGAACGTGCATTTAAAAATGATAAGATAGATTTTATCTGGAATAGTACGTTAAAATCAATCAACGAAAAGGATGGAAAAG
TCGGATCTGTAACACTAATCGATAATGAAGGTAAAGAGACAGATGTTGAAACTGATGGTGTATTCATCTATATCGGTATG
CAGCCCCTGACAAAACCATTTCAACATCTTGGTATCACTGATGAAGTCGGCTATATTATAACGAATGAAGAGATGGAGAC
GAATATTCCTGGAATATTCGCTGCTGGTGACGTTAGACAGAAGAAACTCCGTCAAATTGTAACTGCGACAGGTGACGGCA
GCATTGCTGCACAAAATGCTCAGCATTATATTGAAAGCTTGAATGATTAA

Upstream 100 bases:

>100_bases
ATCATTTTATGAAGGTGTATGAACAGTTCAAGCAAAATAATATTTAAAAATCTGGAATTCATGTATATTATAAGTACTGA
ACAAACATGGAGGTATAATT

Downstream 100 bases:

>100_bases
TATATTCCGACAAATAGATACGCATTTTGTGCGTGTCTATTTTTATGAATTCATGTAGAATGAAATTAAGATGAGGAGGA
ATATATATGTCGAACGAAGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSEIKEYDVIIVGAGPAGMTAAVYASRANLSTIMIERGMPGGQMANTADVENFPGFDLITGPDLSTKMFSHAQKFGAEYT
YGDIKNITVEGDDKIVDLGDKQLKAKAVIIATGAEYKKIGVPGESELGGRGVSYCAVCDGAFFKQKNLVVIGGGDSAVEE
GVYLTKYADKVTIVHRRDTLRAQKILQERAFKNDKIDFIWNSTLKSINEKDGKVGSVTLIDNEGKETDVETDGVFIYIGM
QPLTKPFQHLGITDEVGYIITNEEMETNIPGIFAAGDVRQKKLRQIVTATGDGSIAAQNAQHYIESLND

Sequences:

>Translated_309_residues
MSEIKEYDVIIVGAGPAGMTAAVYASRANLSTIMIERGMPGGQMANTADVENFPGFDLITGPDLSTKMFSHAQKFGAEYT
YGDIKNITVEGDDKIVDLGDKQLKAKAVIIATGAEYKKIGVPGESELGGRGVSYCAVCDGAFFKQKNLVVIGGGDSAVEE
GVYLTKYADKVTIVHRRDTLRAQKILQERAFKNDKIDFIWNSTLKSINEKDGKVGSVTLIDNEGKETDVETDGVFIYIGM
QPLTKPFQHLGITDEVGYIITNEEMETNIPGIFAAGDVRQKKLRQIVTATGDGSIAAQNAQHYIESLND
>Mature_308_residues
SEIKEYDVIIVGAGPAGMTAAVYASRANLSTIMIERGMPGGQMANTADVENFPGFDLITGPDLSTKMFSHAQKFGAEYTY
GDIKNITVEGDDKIVDLGDKQLKAKAVIIATGAEYKKIGVPGESELGGRGVSYCAVCDGAFFKQKNLVVIGGGDSAVEEG
VYLTKYADKVTIVHRRDTLRAQKILQERAFKNDKIDFIWNSTLKSINEKDGKVGSVTLIDNEGKETDVETDGVFIYIGMQ
PLTKPFQHLGITDEVGYIITNEEMETNIPGIFAAGDVRQKKLRQIVTATGDGSIAAQNAQHYIESLND

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=327, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI65787454, Length=327, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI226437568, Length=327, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=39.0625, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=33.7704918032787, Blast_Score=150, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=43.0340557275542, Blast_Score=219, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6321898, Length=330, Percent_Identity=39.6969696969697, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33476; Mature: 33345

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIKEYDVIIVGAGPAGMTAAVYASRANLSTIMIERGMPGGQMANTADVENFPGFDLIT
CCCCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEE
GPDLSTKMFSHAQKFGAEYTYGDIKNITVEGDDKIVDLGDKQLKAKAVIIATGAEYKKIG
CCCCHHHHHHHHHHHCCCCEECCCEEEEECCCCEEEECCCCCEEEEEEEEEECCCEEEEC
VPGESELGGRGVSYCAVCDGAFFKQKNLVVIGGGDSAVEEGVYLTKYADKVTIVHRRDTL
CCCCCCCCCCCCEEEEEECCCEEECCCEEEEECCCHHHHCCEEEEEECCEEEEEECHHHH
RAQKILQERAFKNDKIDFIWNSTLKSINEKDGKVGSVTLIDNEGKETDVETDGVFIYIGM
HHHHHHHHHHCCCCCEEEEECHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEECC
QPLTKPFQHLGITDEVGYIITNEEMETNIPGIFAAGDVRQKKLRQIVTATGDGSIAAQNA
CHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHEECCCCCEEHHHH
QHYIESLND
HHHHHHCCC
>Mature Secondary Structure 
SEIKEYDVIIVGAGPAGMTAAVYASRANLSTIMIERGMPGGQMANTADVENFPGFDLIT
CCCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEE
GPDLSTKMFSHAQKFGAEYTYGDIKNITVEGDDKIVDLGDKQLKAKAVIIATGAEYKKIG
CCCCHHHHHHHHHHHCCCCEECCCEEEEECCCCEEEECCCCCEEEEEEEEEECCCEEEEC
VPGESELGGRGVSYCAVCDGAFFKQKNLVVIGGGDSAVEEGVYLTKYADKVTIVHRRDTL
CCCCCCCCCCCCEEEEEECCCEEECCCEEEEECCCHHHHCCEEEEEECCEEEEEECHHHH
RAQKILQERAFKNDKIDFIWNSTLKSINEKDGKVGSVTLIDNEGKETDVETDGVFIYIGM
HHHHHHHHHHCCCCCEEEEECHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEECC
QPLTKPFQHLGITDEVGYIITNEEMETNIPGIFAAGDVRQKKLRQIVTATGDGSIAAQNA
CHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHEECCCCCEEHHHH
QHYIESLND
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA