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The map label for this gene is scrK [H]

Identifier: 222150624

GI number: 222150624

Start: 398593

End: 399540

Strand: Direct

Name: scrK [H]

Synonym: MCCL_0374

Alternate gene names: 222150624

Gene position: 398593-399540 (Clockwise)

Preceding gene: 222150623

Following gene: 222150625

Centisome position: 18.96

GC content: 41.67

Gene sequence:

>948_bases
ATGCCAAAACTCTATGCTATCGGTGAAGCATTAATTGACTTTATTCCACAGACAAAAGGGGTAGCACTTAAAAATGTTGC
AGCATTTGACACCCAAGTAGGCGGCGCACCTGCTAATGTCGCAAGCTGTGTCGCAAAACTTGGGAAGTCTTCGGTATTGC
TCACGCAACTTGGAAACGATGCGTTTGGGGATCTTATCATTGATACGCTGGATGAGATAGGTGTTGATACATCATTTATA
CAAAGAACAGACGAAGCAAATACAGGGCTTGCTTTTGTAAGCTTAACTGAAGATGGTGAAAGAGACTTTGCTTTCTATCG
TAAGCCATCTGCTGATATGCTGATGAATCACGTAGAAGTTAATTTTACTTCAGCGGATATCCTTCACTTTTGTTCGGTGG
ATTTAATCCCATCTGCAATGAAAGATACCCATGTACAAGTGATTGAACAAATGCATGCTGCAGGTGGCACGGTCGTATTT
GATCCAAACTTAAGGTTCCCATTACGGCCATCGAAAGAAGCGTTAAAAGAAACGGTTCTTGAATTTCTGCCGCATGCACA
TATTATAAAGATTTCAGACGAAGAGCTTGAGTTCTTAACAGGGTCATCACATACTGATTCGATTCAGTCATTATTTAATG
GTTATACACAAGTTGTCATCTATACACAAGGTGCAAACGGCGCATCAATATATACGAAAGATGGCTGCATAGCAAGTCAC
CCGGGTTATACGGTTAATGTGCAGGATACAACGGGGGCAGGTGATGCATTCATCGGTGCTACAATCTATCAGTTACTAGG
TCACGATGCAATACAATATATCAAGCAACACGCAGCAGCAATCCTTATATTCAGTAATAGTGTAGGTGCGCTCACTACTA
CGAATAAAGGGGCAATACAAAGTTTACCCGCGCTACTAGACATTCGACGATTAAAGGAGGAACAGTAA

Upstream 100 bases:

>100_bases
GAATCTTCCCTTCTGAAGATTCTGATGGAGTGCGCGTATCTAGTAGTGACGGTCAGGCCAAGTTAACGATTACTAAGTTC
AATTTGAAAGAAGGGATTTC

Downstream 100 bases:

>100_bases
TATGGCTAAAACAGACAAACAGATTGCACAGGAAGTACTCGACGCAGTAGGAGGACGTGAAAATATTGCTTCGATTGCCC
ATTGTGCAACGCGATTACGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPKLYAIGEALIDFIPQTKGVALKNVAAFDTQVGGAPANVASCVAKLGKSSVLLTQLGNDAFGDLIIDTLDEIGVDTSFI
QRTDEANTGLAFVSLTEDGERDFAFYRKPSADMLMNHVEVNFTSADILHFCSVDLIPSAMKDTHVQVIEQMHAAGGTVVF
DPNLRFPLRPSKEALKETVLEFLPHAHIIKISDEELEFLTGSSHTDSIQSLFNGYTQVVIYTQGANGASIYTKDGCIASH
PGYTVNVQDTTGAGDAFIGATIYQLLGHDAIQYIKQHAAAILIFSNSVGALTTTNKGAIQSLPALLDIRRLKEEQ

Sequences:

>Translated_315_residues
MPKLYAIGEALIDFIPQTKGVALKNVAAFDTQVGGAPANVASCVAKLGKSSVLLTQLGNDAFGDLIIDTLDEIGVDTSFI
QRTDEANTGLAFVSLTEDGERDFAFYRKPSADMLMNHVEVNFTSADILHFCSVDLIPSAMKDTHVQVIEQMHAAGGTVVF
DPNLRFPLRPSKEALKETVLEFLPHAHIIKISDEELEFLTGSSHTDSIQSLFNGYTQVVIYTQGANGASIYTKDGCIASH
PGYTVNVQDTTGAGDAFIGATIYQLLGHDAIQYIKQHAAAILIFSNSVGALTTTNKGAIQSLPALLDIRRLKEEQ
>Mature_314_residues
PKLYAIGEALIDFIPQTKGVALKNVAAFDTQVGGAPANVASCVAKLGKSSVLLTQLGNDAFGDLIIDTLDEIGVDTSFIQ
RTDEANTGLAFVSLTEDGERDFAFYRKPSADMLMNHVEVNFTSADILHFCSVDLIPSAMKDTHVQVIEQMHAAGGTVVFD
PNLRFPLRPSKEALKETVLEFLPHAHIIKISDEELEFLTGSSHTDSIQSLFNGYTQVVIYTQGANGASIYTKDGCIASHP
GYTVNVQDTTGAGDAFIGATIYQLLGHDAIQYIKQHAAAILIFSNSVGALTTTNKGAIQSLPALLDIRRLKEEQ

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=286, Percent_Identity=25.5244755244755, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87082281, Length=271, Percent_Identity=25.0922509225092, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082343, Length=314, Percent_Identity=26.4331210191083, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081971, Length=328, Percent_Identity=24.0853658536585, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=292, Percent_Identity=25.6849315068493, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=26.0726072607261, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 33920; Mature: 33789

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLYAIGEALIDFIPQTKGVALKNVAAFDTQVGGAPANVASCVAKLGKSSVLLTQLGND
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCC
AFGDLIIDTLDEIGVDTSFIQRTDEANTGLAFVSLTEDGERDFAFYRKPSADMLMNHVEV
HHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCEEECCCHHHHHHHHEE
NFTSADILHFCSVDLIPSAMKDTHVQVIEQMHAAGGTVVFDPNLRFPLRPSKEALKETVL
EECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHH
EFLPHAHIIKISDEELEFLTGSSHTDSIQSLFNGYTQVVIYTQGANGASIYTKDGCIASH
HHCCCCEEEEECCCHHHEECCCCCHHHHHHHHCCCEEEEEEEECCCCCEEEECCCEEECC
PGYTVNVQDTTGAGDAFIGATIYQLLGHDAIQYIKQHAAAILIFSNSVGALTTTNKGAIQ
CCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHCEEEEEEECCCCCEEECCCCHHH
SLPALLDIRRLKEEQ
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
PKLYAIGEALIDFIPQTKGVALKNVAAFDTQVGGAPANVASCVAKLGKSSVLLTQLGND
CCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCC
AFGDLIIDTLDEIGVDTSFIQRTDEANTGLAFVSLTEDGERDFAFYRKPSADMLMNHVEV
HHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCEEECCCHHHHHHHHEE
NFTSADILHFCSVDLIPSAMKDTHVQVIEQMHAAGGTVVFDPNLRFPLRPSKEALKETVL
EECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHH
EFLPHAHIIKISDEELEFLTGSSHTDSIQSLFNGYTQVVIYTQGANGASIYTKDGCIASH
HHCCCCEEEEECCCHHHEECCCCCHHHHHHHHCCCEEEEEEEECCCCCEEEECCCEEECC
PGYTVNVQDTTGAGDAFIGATIYQLLGHDAIQYIKQHAAAILIFSNSVGALTTTNKGAIQ
CCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHCEEEEEEECCCCCEEECCCCHHH
SLPALLDIRRLKEEQ
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2174811 [H]