Click here to switch to the map view.

The map label for this gene is pbuG [H]

Identifier: 222150442

GI number: 222150442

Start: 201254

End: 202588

Strand: Direct

Name: pbuG [H]

Synonym: MCCL_0192

Alternate gene names: 222150442

Gene position: 201254-202588 (Clockwise)

Preceding gene: 222150440

Following gene: 222150444

Centisome position: 9.57

GC content: 39.93

Gene sequence:

>1335_bases
ATGAGAAATTATTTTAAGTTTGATGAATTAGGCACAAGTTATAAGCGAGAGATAATGGGAGGCTTAACGACATTCCTATC
GATGGCATACATATTAGCGGTCAATCCTGCAATGTTATCACTCGCTGGTGTTGAAGGTATCCCGGATAGTATGCGTATGG
ATGCTGGTGCGGTCTTTGTTGCGACAATTCTTGCTTCAATAGTAGGCTGTTTGTTCATGGGACTAATTGCAAACTATCCT
ATTGCGTTAGCCCCTGGTATGGGATTGAATGCATTTTTTGCATTCACAGTCGTATTACAGTACAACATTCCGTGGCAGAC
AGGTTTAACGGGTGTACTATTCTCAGGATTATTCTTTGCATTACTGACGATGACAGGTTTACGTGAAACGATTATCAACG
CAATTCCTTTCGAACTGAAGATGGCTGTATCAGCGGGTATAGGTCTTTTTATTACCTTTGTAGGTTTAAAAGGTGCAGGC
ATTGTAAAAGGGAATGAATCGACTTTAGTATCATTAGGTAATGTCCATGATCCGCATGTATTATTAGCGGTTGGTGGCAT
TGCATTAACAATTATTCTTATGGCAAAACGCGTTCCAGGAAGCATCTTTATCGGGATGGTATTAACAGCGATATTTGGTA
TGCTCTTCGGACTTATTGATGCACCAAAGCAAATTGTCGGTTCAGTGCCAAGTATCGAACCAACATTCGGAAAAGCATTC
GATGCATTTGCACATCCAGAACACATCTTTAACTTGCAATTTTTAGTGATCGTATTAACATTCTTATTTATTGACTTCTT
TGATACAGCGGGTACATTAGTTGCTGTTGCAACGCAGGCGAACCTAGTGAAGGATAACAAATTGCCACGCGCGGGACGTT
CTTTATTTGCAGATTCATTAGCGACAATTGTAGGTGCTATTTTCGGTACGTCTACGACAACCTCATATATCGAATCTTCA
GCGGGGGTTGCAGTAGGTGCCAGAACAGGATTTGCAAGTGTGGTTACGGCATTATGTTTCGCCTTAGCACTTTTCTTCTC
ACCTCTTATGTCCGTTGTAACGAGTGCGGTGACTGCACCTGCTCTAGTAATCGTGGGTGTATTAATGGTGGCGAACTTAA
ATAAAATAGAGTGGAACAAGTTTGAAATTGCAGTTCCTGCATTTTTAACTATTATTATGATGCCACTTACGTATTCGATT
GCTACAGGTATTGCATGTGGATTTATTTTCTATCCGATAACGATGCTAATGGCAAATCGCAGAAAAGAGATTCACCCAAT
TATGTATTTCATGGCAGTAGTATTTATTTTATACTTTATATTTATCCAGCACTAA

Upstream 100 bases:

>100_bases
ATACGAATATTAAAATTAAAAATGATAAAATTGTATTGATTTTTCCGAACATTGAGATTAGACTATACAAGTATAAAAAT
TAAAAAGAGGGAAGTGCACA

Downstream 100 bases:

>100_bases
AAAACAAGGAGCTCAGACATGTGTCTGAGCTCCTTGTTTTTATTTTTCTTTGTTATAATCTCTCACAGTCTCGCCGCTGC
GGTATGGATCATAGTAAGTC

Product: xanthine/uracil permeases family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MRNYFKFDELGTSYKREIMGGLTTFLSMAYILAVNPAMLSLAGVEGIPDSMRMDAGAVFVATILASIVGCLFMGLIANYP
IALAPGMGLNAFFAFTVVLQYNIPWQTGLTGVLFSGLFFALLTMTGLRETIINAIPFELKMAVSAGIGLFITFVGLKGAG
IVKGNESTLVSLGNVHDPHVLLAVGGIALTIILMAKRVPGSIFIGMVLTAIFGMLFGLIDAPKQIVGSVPSIEPTFGKAF
DAFAHPEHIFNLQFLVIVLTFLFIDFFDTAGTLVAVATQANLVKDNKLPRAGRSLFADSLATIVGAIFGTSTTTSYIESS
AGVAVGARTGFASVVTALCFALALFFSPLMSVVTSAVTAPALVIVGVLMVANLNKIEWNKFEIAVPAFLTIIMMPLTYSI
ATGIACGFIFYPITMLMANRRKEIHPIMYFMAVVFILYFIFIQH

Sequences:

>Translated_444_residues
MRNYFKFDELGTSYKREIMGGLTTFLSMAYILAVNPAMLSLAGVEGIPDSMRMDAGAVFVATILASIVGCLFMGLIANYP
IALAPGMGLNAFFAFTVVLQYNIPWQTGLTGVLFSGLFFALLTMTGLRETIINAIPFELKMAVSAGIGLFITFVGLKGAG
IVKGNESTLVSLGNVHDPHVLLAVGGIALTIILMAKRVPGSIFIGMVLTAIFGMLFGLIDAPKQIVGSVPSIEPTFGKAF
DAFAHPEHIFNLQFLVIVLTFLFIDFFDTAGTLVAVATQANLVKDNKLPRAGRSLFADSLATIVGAIFGTSTTTSYIESS
AGVAVGARTGFASVVTALCFALALFFSPLMSVVTSAVTAPALVIVGVLMVANLNKIEWNKFEIAVPAFLTIIMMPLTYSI
ATGIACGFIFYPITMLMANRRKEIHPIMYFMAVVFILYFIFIQH
>Mature_444_residues
MRNYFKFDELGTSYKREIMGGLTTFLSMAYILAVNPAMLSLAGVEGIPDSMRMDAGAVFVATILASIVGCLFMGLIANYP
IALAPGMGLNAFFAFTVVLQYNIPWQTGLTGVLFSGLFFALLTMTGLRETIINAIPFELKMAVSAGIGLFITFVGLKGAG
IVKGNESTLVSLGNVHDPHVLLAVGGIALTIILMAKRVPGSIFIGMVLTAIFGMLFGLIDAPKQIVGSVPSIEPTFGKAF
DAFAHPEHIFNLQFLVIVLTFLFIDFFDTAGTLVAVATQANLVKDNKLPRAGRSLFADSLATIVGAIFGTSTTTSYIESS
AGVAVGARTGFASVVTALCFALALFFSPLMSVVTSAVTAPALVIVGVLMVANLNKIEWNKFEIAVPAFLTIIMMPLTYSI
ATGIACGFIFYPITMLMANRRKEIHPIMYFMAVVFILYFIFIQH

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=444, Percent_Identity=39.6396396396396, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI87082309, Length=445, Percent_Identity=38.4269662921348, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1790499, Length=444, Percent_Identity=33.1081081081081, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI48994909, Length=430, Percent_Identity=34.6511627906977, Blast_Score=204, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47529; Mature: 47529

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNYFKFDELGTSYKREIMGGLTTFLSMAYILAVNPAMLSLAGVEGIPDSMRMDAGAVFV
CCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHCCHHHHH
ATILASIVGCLFMGLIANYPIALAPGMGLNAFFAFTVVLQYNIPWQTGLTGVLFSGLFFA
HHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHEECCCHHHCHHHHHHHHHHHH
LLTMTGLRETIINAIPFELKMAVSAGIGLFITFVGLKGAGIVKGNESTLVSLGNVHDPHV
HHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCHH
LLAVGGIALTIILMAKRVPGSIFIGMVLTAIFGMLFGLIDAPKQIVGSVPSIEPTFGKAF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
DAFAHPEHIFNLQFLVIVLTFLFIDFFDTAGTLVAVATQANLVKDNKLPRAGRSLFADSL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCCHHHHHHHHHHH
ATIVGAIFGTSTTTSYIESSAGVAVGARTGFASVVTALCFALALFFSPLMSVVTSAVTAP
HHHHHHHHCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVIVGVLMVANLNKIEWNKFEIAVPAFLTIIMMPLTYSIATGIACGFIFYPITMLMANR
HHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RKEIHPIMYFMAVVFILYFIFIQH
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNYFKFDELGTSYKREIMGGLTTFLSMAYILAVNPAMLSLAGVEGIPDSMRMDAGAVFV
CCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHCCHHHHH
ATILASIVGCLFMGLIANYPIALAPGMGLNAFFAFTVVLQYNIPWQTGLTGVLFSGLFFA
HHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHEECCCHHHCHHHHHHHHHHHH
LLTMTGLRETIINAIPFELKMAVSAGIGLFITFVGLKGAGIVKGNESTLVSLGNVHDPHV
HHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCHH
LLAVGGIALTIILMAKRVPGSIFIGMVLTAIFGMLFGLIDAPKQIVGSVPSIEPTFGKAF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
DAFAHPEHIFNLQFLVIVLTFLFIDFFDTAGTLVAVATQANLVKDNKLPRAGRSLFADSL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCCHHHHHHHHHHH
ATIVGAIFGTSTTTSYIESSAGVAVGARTGFASVVTALCFALALFFSPLMSVVTSAVTAP
HHHHHHHHCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVIVGVLMVANLNKIEWNKFEIAVPAFLTIIMMPLTYSIATGIACGFIFYPITMLMANR
HHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RKEIHPIMYFMAVVFILYFIFIQH
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]