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The map label for this gene is citT [C]

Identifier: 222150440

GI number: 222150440

Start: 198769

End: 200238

Strand: Direct

Name: citT [C]

Synonym: MCCL_0190

Alternate gene names: 222150440

Gene position: 198769-200238 (Clockwise)

Preceding gene: 222150439

Following gene: 222150442

Centisome position: 9.45

GC content: 41.56

Gene sequence:

>1470_bases
TTGAGCTTTCTTGTATTGATTGCGATCGTATTGCTACCGACACCTGCTTCTTTACCAGTGATGGGTAAGATGGCACTTGC
GATTCTTGCATTTGCCGTAATTATGTGGGTTACTGAAGCGGTAAGTTATCCTGTTTCCAGTACGATGATTGTTGCTTTAA
TCATCACACTTATTGGGTTCAGCCCGATCGAGAAACTTGGGCCATCGATGGGAAATCCAATGGCTGCAGGTAAACCGTTA
ACTGAAGATGCCTTGTTCGGTACACAGAATGCATTAAAGATTGCCTTTAGTGGATTTTCAAGTTCGGCAGTAGCACTCGT
TGCAGCTGCGCTGTTTTTAGCCACGGCTATGCAAGTAACAAACTTGCATAAACGTCTTGCGCTTTTAGTACTCTCGGTAG
TAGGGAATAAAACGAATGCAGTTGTCGCAGGTTCTATCATTGTTTCAATCATTCTTGCATTTTTCGTTCCTTCAGCAACT
GCACGTGCAAGCGCTGTCGTACCGATACTGCTTGGTATGGTTACAGCGTTTGGCGCTAAGAAAGAATCCCGCCTGGCAGC
ATTGCTTGTGATTACCGCTGTCCAAGCTGTGTCTATATGGAATATCGGTATTAAGACTGGAGCCGCTCAAAATATGGTTG
CAATGGGCTTTATCAATAAAACCTTCAACGAAGATATCTCTTGGGGTCAATGGTTTATGTACGCGGCACCGTGGTCCATT
GTTATGTCGATTGTCTTATACTTTGTCATGATTAATTTGATTAAACCTGAAACGAAAGAAATTGAAGGTGGAAAGGAACT
TGTAAAGGCACAGCTAGCAGAACTTGGACCGGTGACGCCGAAAGAATGGCGATTAATTGCAATCTCAGTAGCATTGCTCT
TATTCTGGGCAACTGAAGGTAAGTTTCATCCAATTGATTCTTCATCGATTACTTTAATTGCGTTAGCTATTATGCTCACT
CCGAAGATTGGCATCTTCTCGTGGAGCGATGTAGAAAAATTGATTCCATGGGGAACAATTATAGTGTTTGCAATTGGGAT
ATCTTTAGGGAATTTATTGCTGCAGACGACTGGGGCGCAGTGGCTAAGTGATAAGACCTTTGGATTGATGGGGTTAGAGC
ATTTGCCGTTACTTGCTACAATTGCTTTAATTACGATATTTAATATTCTGATTCATTTAGGATTCGCGAGCGCAACAAGC
TTATCAAGTGCACTTATACCAGTGTTTATTGCACTTACAAGTACTTTAGGATTAAAGGATAATGCAGTTGGATTCGTATT
GATACAACAATTTGTGATTAGCTTTGGATTCTTGCTTCCGGTGTCAGCGCCACAAAACATGCTTGCATATGGTACAGGCA
CTTTCACTGTAAAAGATTTCTTGAAGTCGGGTATACCTTTAACGGTTATTGGCTATTTACTTATCCTGCTCTTCAGCGCA
ACTTATTGGAAGTGGATTGGATTAATATAA

Upstream 100 bases:

>100_bases
CAATACTTCACAAATTGTTAAAATAGAAGTGAATAAAATAGGGGGTGTTTCTATGGAAAACGTAAAACAAAAGAAGAATC
TCAAACCAATTTGGATTATT

Downstream 100 bases:

>100_bases
TCAACGAAAAGAAAGATGCTGAGACAAATGTCTCAGCATCTTTTTATGCATCTTGAGATAAGATTTTCATATCTTTAGCA
TCGAGTTCAAACTCTTTCGT

Product: anion transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSFLVLIAIVLLPTPASLPVMGKMALAILAFAVIMWVTEAVSYPVSSTMIVALIITLIGFSPIEKLGPSMGNPMAAGKPL
TEDALFGTQNALKIAFSGFSSSAVALVAAALFLATAMQVTNLHKRLALLVLSVVGNKTNAVVAGSIIVSIILAFFVPSAT
ARASAVVPILLGMVTAFGAKKESRLAALLVITAVQAVSIWNIGIKTGAAQNMVAMGFINKTFNEDISWGQWFMYAAPWSI
VMSIVLYFVMINLIKPETKEIEGGKELVKAQLAELGPVTPKEWRLIAISVALLLFWATEGKFHPIDSSSITLIALAIMLT
PKIGIFSWSDVEKLIPWGTIIVFAIGISLGNLLLQTTGAQWLSDKTFGLMGLEHLPLLATIALITIFNILIHLGFASATS
LSSALIPVFIALTSTLGLKDNAVGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKSGIPLTVIGYLLILLFSA
TYWKWIGLI

Sequences:

>Translated_489_residues
MSFLVLIAIVLLPTPASLPVMGKMALAILAFAVIMWVTEAVSYPVSSTMIVALIITLIGFSPIEKLGPSMGNPMAAGKPL
TEDALFGTQNALKIAFSGFSSSAVALVAAALFLATAMQVTNLHKRLALLVLSVVGNKTNAVVAGSIIVSIILAFFVPSAT
ARASAVVPILLGMVTAFGAKKESRLAALLVITAVQAVSIWNIGIKTGAAQNMVAMGFINKTFNEDISWGQWFMYAAPWSI
VMSIVLYFVMINLIKPETKEIEGGKELVKAQLAELGPVTPKEWRLIAISVALLLFWATEGKFHPIDSSSITLIALAIMLT
PKIGIFSWSDVEKLIPWGTIIVFAIGISLGNLLLQTTGAQWLSDKTFGLMGLEHLPLLATIALITIFNILIHLGFASATS
LSSALIPVFIALTSTLGLKDNAVGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKSGIPLTVIGYLLILLFSA
TYWKWIGLI
>Mature_488_residues
SFLVLIAIVLLPTPASLPVMGKMALAILAFAVIMWVTEAVSYPVSSTMIVALIITLIGFSPIEKLGPSMGNPMAAGKPLT
EDALFGTQNALKIAFSGFSSSAVALVAAALFLATAMQVTNLHKRLALLVLSVVGNKTNAVVAGSIIVSIILAFFVPSATA
RASAVVPILLGMVTAFGAKKESRLAALLVITAVQAVSIWNIGIKTGAAQNMVAMGFINKTFNEDISWGQWFMYAAPWSIV
MSIVLYFVMINLIKPETKEIEGGKELVKAQLAELGPVTPKEWRLIAISVALLLFWATEGKFHPIDSSSITLIALAIMLTP
KIGIFSWSDVEKLIPWGTIIVFAIGISLGNLLLQTTGAQWLSDKTFGLMGLEHLPLLATIALITIFNILIHLGFASATSL
SSALIPVFIALTSTLGLKDNAVGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKSGIPLTVIGYLLILLFSAT
YWKWIGLI

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. SODIT1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=464, Percent_Identity=21.1206896551724, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI301069346, Length=537, Percent_Identity=21.9739292364991, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI301069349, Length=293, Percent_Identity=23.2081911262799, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI31795546, Length=349, Percent_Identity=19.7707736389685, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786829, Length=476, Percent_Identity=25.4201680672269, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786986, Length=409, Percent_Identity=28.6063569682152, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1789444, Length=489, Percent_Identity=25.5623721881391, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI32564681, Length=458, Percent_Identity=22.4890829694323, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32565804, Length=400, Percent_Identity=22.75, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71988385, Length=400, Percent_Identity=22.75, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324340, Length=483, Percent_Identity=22.5672877846791, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281362116, Length=468, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281362114, Length=472, Percent_Identity=23.0932203389831, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362112, Length=472, Percent_Identity=23.0932203389831, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45551633, Length=533, Percent_Identity=21.2007504690432, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281366409, Length=534, Percent_Identity=21.1610486891386, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737623, Length=534, Percent_Identity=21.1610486891386, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666468, Length=534, Percent_Identity=21.1610486891386, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 52144; Mature: 52013

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLVLIAIVLLPTPASLPVMGKMALAILAFAVIMWVTEAVSYPVSSTMIVALIITLIGF
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
SPIEKLGPSMGNPMAAGKPLTEDALFGTQNALKIAFSGFSSSAVALVAAALFLATAMQVT
CCHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHH
NLHKRLALLVLSVVGNKTNAVVAGSIIVSIILAFFVPSATARASAVVPILLGMVTAFGAK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
KESRLAALLVITAVQAVSIWNIGIKTGAAQNMVAMGFINKTFNEDISWGQWFMYAAPWSI
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHCCHHH
VMSIVLYFVMINLIKPETKEIEGGKELVKAQLAELGPVTPKEWRLIAISVALLLFWATEG
HHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
KFHPIDSSSITLIALAIMLTPKIGIFSWSDVEKLIPWGTIIVFAIGISLGNLLLQTTGAQ
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
WLSDKTFGLMGLEHLPLLATIALITIFNILIHLGFASATSLSSALIPVFIALTSTLGLKD
HHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
NAVGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKSGIPLTVIGYLLILLFSA
CCHHHHHHHHHHHHHHHHEECCCCCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
TYWKWIGLI
HHHHHHCCC
>Mature Secondary Structure 
SFLVLIAIVLLPTPASLPVMGKMALAILAFAVIMWVTEAVSYPVSSTMIVALIITLIGF
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
SPIEKLGPSMGNPMAAGKPLTEDALFGTQNALKIAFSGFSSSAVALVAAALFLATAMQVT
CCHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHH
NLHKRLALLVLSVVGNKTNAVVAGSIIVSIILAFFVPSATARASAVVPILLGMVTAFGAK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
KESRLAALLVITAVQAVSIWNIGIKTGAAQNMVAMGFINKTFNEDISWGQWFMYAAPWSI
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHCCHHH
VMSIVLYFVMINLIKPETKEIEGGKELVKAQLAELGPVTPKEWRLIAISVALLLFWATEG
HHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
KFHPIDSSSITLIALAIMLTPKIGIFSWSDVEKLIPWGTIIVFAIGISLGNLLLQTTGAQ
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
WLSDKTFGLMGLEHLPLLATIALITIFNILIHLGFASATSLSSALIPVFIALTSTLGLKD
HHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
NAVGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKSGIPLTVIGYLLILLFSA
CCHHHHHHHHHHHHHHHHEECCCCCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
TYWKWIGLI
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8405966 [H]