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The map label for this gene is lytR [H]

Identifier: 222150360

GI number: 222150360

Start: 116318

End: 117028

Strand: Direct

Name: lytR [H]

Synonym: MCCL_0110

Alternate gene names: 222150360

Gene position: 116318-117028 (Clockwise)

Preceding gene: 222150359

Following gene: 222150361

Centisome position: 5.53

GC content: 32.77

Gene sequence:

>711_bases
ATGAGAATATTAATTGTAGATGATGAACCATTAGCAAGAAATGAGCTGCGTTATTTACTTAATAACATCGATAATACATT
AGTGGTTGATGAAGCGGATTCTGTAGAAGAAACATTGACATCATTACTATCAGAAACATATGAATTATTGTTTTTGGATA
TCAACTTGATTGATGAAAGCGGGCTTGAACTTGCCGAAAAGATTAATAAGATGAAGCATCCGCCTAAGATTGTCTTTGCA
ACAGCACATGATAGTTTTGCTGTGAAGGCCTTTGAATTGAATGCATTAGATTATATATTAAAACCTTTCGAACAAAAGCG
TATTGAAGCAGCATTGAATAAAGCCAAGGCATCATCTATCAATACAAATCAAGAATCGAAATTGCCAACCTTGTCGATAC
AAATTGATGACAAAATCTATGTCATTAATATACAGGATATTATCGCCTTGTATGTAGAAGAAGGGCAATTAAATATCATA
ACTGTAAACTCAGAATATGCGATTCACGAGCCATTAAGTGCATTTGAAAAGAAGCTTCCAGAGAATGTATTTATGCGCAT
ACATCGATCAAGCATTATTAACAAACATCATATTAAATCAGCAGAACAATGGTTTAATCATACTTATCAAGTGCAGTTGA
CGAAAGATATAAAACTGCAAGTCTCAAGATCGTATATAAAGCAATTTAAACACGAAATAGGGCTCAAATAA

Upstream 100 bases:

>100_bases
TCATCGGATTGTACAATAGTAATGCGCAACTAAATTTTACGACAAGTGATTCGGGTACTAAGTTTTATACATCTATACCT
TTAGAGAGGGAGGAAGATGC

Downstream 100 bases:

>100_bases
TTTGAGTCCTATTTTTTGCATTTCAACACTTAATTTTTGCATTTCATCGTGAAAACTCTCACAAAACAATATGTAAGCGG
TATGATGTAATCAAGATAAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MRILIVDDEPLARNELRYLLNNIDNTLVVDEADSVEETLTSLLSETYELLFLDINLIDESGLELAEKINKMKHPPKIVFA
TAHDSFAVKAFELNALDYILKPFEQKRIEAALNKAKASSINTNQESKLPTLSIQIDDKIYVINIQDIIALYVEEGQLNII
TVNSEYAIHEPLSAFEKKLPENVFMRIHRSSIINKHHIKSAEQWFNHTYQVQLTKDIKLQVSRSYIKQFKHEIGLK

Sequences:

>Translated_236_residues
MRILIVDDEPLARNELRYLLNNIDNTLVVDEADSVEETLTSLLSETYELLFLDINLIDESGLELAEKINKMKHPPKIVFA
TAHDSFAVKAFELNALDYILKPFEQKRIEAALNKAKASSINTNQESKLPTLSIQIDDKIYVINIQDIIALYVEEGQLNII
TVNSEYAIHEPLSAFEKKLPENVFMRIHRSSIINKHHIKSAEQWFNHTYQVQLTKDIKLQVSRSYIKQFKHEIGLK
>Mature_236_residues
MRILIVDDEPLARNELRYLLNNIDNTLVVDEADSVEETLTSLLSETYELLFLDINLIDESGLELAEKINKMKHPPKIVFA
TAHDSFAVKAFELNALDYILKPFEQKRIEAALNKAKASSINTNQESKLPTLSIQIDDKIYVINIQDIIALYVEEGQLNII
TVNSEYAIHEPLSAFEKKLPENVFMRIHRSSIINKHHIKSAEQWFNHTYQVQLTKDIKLQVSRSYIKQFKHEIGLK

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=245, Percent_Identity=35.5102040816327, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082052, Length=243, Percent_Identity=30.8641975308642, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27232; Mature: 27232

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIVDDEPLARNELRYLLNNIDNTLVVDEADSVEETLTSLLSETYELLFLDINLIDES
CEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHEEEEEEEEEECCC
GLELAEKINKMKHPPKIVFATAHDSFAVKAFELNALDYILKPFEQKRIEAALNKAKASSI
CHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEHHHHHHHHCHHHHHHHHHHHHHHHCCCC
NTNQESKLPTLSIQIDDKIYVINIQDIIALYVEEGQLNIITVNSEYAIHEPLSAFEKKLP
CCCCCCCCCEEEEEECCEEEEEEHHHEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCC
ENVFMRIHRSSIINKHHIKSAEQWFNHTYQVQLTKDIKLQVSRSYIKQFKHEIGLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRILIVDDEPLARNELRYLLNNIDNTLVVDEADSVEETLTSLLSETYELLFLDINLIDES
CEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHEEEEEEEEEECCC
GLELAEKINKMKHPPKIVFATAHDSFAVKAFELNALDYILKPFEQKRIEAALNKAKASSI
CHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEHHHHHHHHCHHHHHHHHHHHHHHHCCCC
NTNQESKLPTLSIQIDDKIYVINIQDIIALYVEEGQLNIITVNSEYAIHEPLSAFEKKLP
CCCCCCCCCEEEEEECCEEEEEEHHHEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCC
ENVFMRIHRSSIINKHHIKSAEQWFNHTYQVQLTKDIKLQVSRSYIKQFKHEIGLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA