BacMap

Definition	Macrococcus caseolyticus JCSC5402, complete genome.
Accession	NC_011999
Length	2,102,324

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The map label for this gene is yhxD [H]

Identifier: 222150340

GI number: 222150340

Start: 93683

End: 94558

Strand: Direct

Name: yhxD [H]

Synonym: MCCL_0090

Alternate gene names: 222150340

Gene position: 93683-94558 (Clockwise)

Preceding gene: 222150339

Following gene: 222150341

Centisome position: 4.46

GC content: 40.53

Gene sequence:

>876_bases
ATGTCAAATCCATTAAATAAATATTATAATGCGTCTTATGAAAAGCAACCACAAGCATACCCAGGTATTCAGAGTGAAAT
GAAGCCGGTACCAGATTGTGGCGAACATTCATATAAAGGGGCAGATAAGCTTACTGACAAGAAAGCATTCGTTACCGGAG
GAGACTCAGGTATTGGTAGAGCAGCTGCAATTGCTTATGCTAAAGAAGGTGCAGATGTCGCAATCAACTATCATCCAGAT
GAACAAAAAGACGCAGAAGATGTAAAGCGTGTCATTGAAACTGTAGGCAGAAAGTGCGTATTATTGCCTGGTGACTTACG
TGAGTCAACATTTGCGCGTGAAGTAGCAATTAAAGCATATGAAGCATTAGGTGGATTAGATATACTAGTATTAAATGCAG
GTATGCAGCAGTTTGAATATGATATTGAGCAACTGGATGAACAGCAAGTACGTGATACATTCGAAGTGAATGTATTCTCA
AATATCTTTACGATACAAAGCGTATTGAAACATTTACAGCCAGGTGCAAGCATTATTATTACAAGTTCTATTCAAGGTGT
TAAGCCGAGTGCGCATCTTGTTGACTATGCAATGACGAAAAGTTGTAATATTTCAATGACGAAGAGCTTAGCAGCACAAC
TTGGGCCTAAAGGCATTCGAGTGAACAGTGTAGCGCCTGGACCAGTATGGACACCACTTCAAATTAGTGGAGGTCAGCCA
CAGGATAATATTCCTGAATTCGGTAAAAAAGAACCGCTTGGTAGAGCAGGGCAACCCGTAGAGCTCGCAGATGTTTATGT
TTTACTTGCAAGTGACAATGCAAGCTATATTACCGGACAAGTTTATGGTATTACCGGTGGCTCACCAATCAACTAA

Upstream 100 bases:

>100_bases
GGTACTCTCTCTATCTCTTTGATGTATAGTTTTATACCCTGGATAATTAAACAAGCAACGATAGGGTATTGTTAATTATA
CCAATCAAGGAGGTCATACT

Downstream 100 bases:

>100_bases
AATCTCCCGTTAAGGGAGATTTTTTTGTGAAATATACTTATATAGCATCAGTTTTGATTTTTTGCGATATACTGTATTCT
CAAACCATTATTGATTTGAA

Product: short-chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: ORFY [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSNPLNKYYNASYEKQPQAYPGIQSEMKPVPDCGEHSYKGADKLTDKKAFVTGGDSGIGRAAAIAYAKEGADVAINYHPD
EQKDAEDVKRVIETVGRKCVLLPGDLRESTFAREVAIKAYEALGGLDILVLNAGMQQFEYDIEQLDEQQVRDTFEVNVFS
NIFTIQSVLKHLQPGASIIITSSIQGVKPSAHLVDYAMTKSCNISMTKSLAAQLGPKGIRVNSVAPGPVWTPLQISGGQP
QDNIPEFGKKEPLGRAGQPVELADVYVLLASDNASYITGQVYGITGGSPIN

Sequences:

>Translated_291_residues
MSNPLNKYYNASYEKQPQAYPGIQSEMKPVPDCGEHSYKGADKLTDKKAFVTGGDSGIGRAAAIAYAKEGADVAINYHPD
EQKDAEDVKRVIETVGRKCVLLPGDLRESTFAREVAIKAYEALGGLDILVLNAGMQQFEYDIEQLDEQQVRDTFEVNVFS
NIFTIQSVLKHLQPGASIIITSSIQGVKPSAHLVDYAMTKSCNISMTKSLAAQLGPKGIRVNSVAPGPVWTPLQISGGQP
QDNIPEFGKKEPLGRAGQPVELADVYVLLASDNASYITGQVYGITGGSPIN
>Mature_290_residues
SNPLNKYYNASYEKQPQAYPGIQSEMKPVPDCGEHSYKGADKLTDKKAFVTGGDSGIGRAAAIAYAKEGADVAINYHPDE
QKDAEDVKRVIETVGRKCVLLPGDLRESTFAREVAIKAYEALGGLDILVLNAGMQQFEYDIEQLDEQQVRDTFEVNVFSN
IFTIQSVLKHLQPGASIIITSSIQGVKPSAHLVDYAMTKSCNISMTKSLAAQLGPKGIRVNSVAPGPVWTPLQISGGQPQ
DNIPEFGKKEPLGRAGQPVELADVYVLLASDNASYITGQVYGITGGSPIN

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=32.9411764705882, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=29.9610894941634, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=30.5555555555556, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=31.0077519379845, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=31.1688311688312, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=27.7992277992278, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI33667109, Length=204, Percent_Identity=31.8627450980392, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=28.9795918367347, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI66933014, Length=237, Percent_Identity=32.0675105485232, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI32455239, Length=146, Percent_Identity=31.5068493150685, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI5031765, Length=146, Percent_Identity=31.5068493150685, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI4503301, Length=199, Percent_Identity=28.1407035175879, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789378, Length=287, Percent_Identity=57.4912891986063, Blast_Score=339, Evalue=1e-94,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=32.7935222672065, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87082100, Length=264, Percent_Identity=32.1969696969697, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=30.7377049180328, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=32.520325203252, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=29.7619047619048, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=30.5220883534137, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=31.5573770491803, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=28.0155642023346, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=26.9076305220884, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=28.6290322580645, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787526, Length=255, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=32.9545454545455, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=34.9809885931559, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=31.9391634980989, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=31.1787072243346, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=262, Percent_Identity=29.3893129770992, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=28.4584980237154, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.9242424242424, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=31.3253012048193, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=30.0751879699248, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=282, Percent_Identity=30.4964539007092, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=32.089552238806, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=32.5301204819277, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=28.3400809716599, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.4820717131474, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=31.9548872180451, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.7878787878788, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=29.5454545454545, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=30.6818181818182, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=28.6821705426357, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=30.3370786516854, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=28.4132841328413, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=28.6792452830189, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=25.7936507936508, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=275, Percent_Identity=29.4545454545455, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=30.8823529411765, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=28.5185185185185, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=29.4820717131474, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=240, Percent_Identity=24.5833333333333, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=31.3829787234043, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=30.8080808080808, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=32.8, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=30.0395256916996, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=29.2, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=29.0322580645161, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=29.5546558704453, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24644337, Length=231, Percent_Identity=32.9004329004329, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=32.4110671936759, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=32.4, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31365; Mature: 31234

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPLNKYYNASYEKQPQAYPGIQSEMKPVPDCGEHSYKGADKLTDKKAFVTGGDSGIGR
CCCCHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHCCCCEEEECCCCCCCH
AAAIAYAKEGADVAINYHPDEQKDAEDVKRVIETVGRKCVLLPGDLRESTFAREVAIKAY
HHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHH
EALGGLDILVLNAGMQQFEYDIEQLDEQQVRDTFEVNVFSNIFTIQSVLKHLQPGASIII
HHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCCEEEE
TSSIQGVKPSAHLVDYAMTKSCNISMTKSLAAQLGPKGIRVNSVAPGPVWTPLQISGGQP
ECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEECCCCC
QDNIPEFGKKEPLGRAGQPVELADVYVLLASDNASYITGQVYGITGGSPIN
CCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
SNPLNKYYNASYEKQPQAYPGIQSEMKPVPDCGEHSYKGADKLTDKKAFVTGGDSGIGR
CCCHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHCCCCEEEECCCCCCCH
AAAIAYAKEGADVAINYHPDEQKDAEDVKRVIETVGRKCVLLPGDLRESTFAREVAIKAY
HHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHH
EALGGLDILVLNAGMQQFEYDIEQLDEQQVRDTFEVNVFSNIFTIQSVLKHLQPGASIII
HHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCCEEEE
TSSIQGVKPSAHLVDYAMTKSCNISMTKSLAAQLGPKGIRVNSVAPGPVWTPLQISGGQP
ECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEECCCCC
QDNIPEFGKKEPLGRAGQPVELADVYVLLASDNASYITGQVYGITGGSPIN
CCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8196543 [H]