Click here to switch to the map view.

The map label for this gene is tctD [H]

Identifier: 222111264

GI number: 222111264

Start: 2225247

End: 2225933

Strand: Direct

Name: tctD [H]

Synonym: Dtpsy_2073

Alternate gene names: 222111264

Gene position: 2225247-2225933 (Clockwise)

Preceding gene: 222111260

Following gene: 222111265

Centisome position: 58.61

GC content: 70.16

Gene sequence:

>687_bases
ATGCAACTGCTTCTCGTCGAAGACGACGCCACCATGCAGGCCACGCTGCAGCGCTCGTTGGCGCGCCGCGGCATGGCCGT
TACCGCCCTTGCGGACGGGCGCGCCGCGCTGGCCGAATGGCGCGCGCACCCGCCCGACGCCGTGGTGCTGGACCTCACCC
TGCCCGGCCTGGACGGCCTGCAGGTACTGCAACAGGCACGCGCCGGCGGCCTGCGCACCCCCGTGCTGCTGCTGACCGCG
CGCGGCACCGTGGGCGACCGCGTGCTGGGCCTGAACGCGGGGGCCGACGACTACCTGCCCAAGCCCTTCGACCTGGACGA
GCTGGAGGCCCGGCTGCGCGCCCTGCTGCGCCGCAGCGGCGGCGATACGGCAGATGACAAACAGGCCTCCAACGCCCTGG
TGATGGGCGCCCTGCGCTATGAAAAAGAAAGCGGCGCCATCTATCTGCACGATGCGCCCATGGACCTCACCCCGCGGGAG
TTGGCGCTGCTGCGCACCCTGCTGACCCAGCCGGGGCGCGCAGTCGCCAAGGAGCGGCTGTATGAGCTGGTCTTCCCCGG
CCAGAGCGAGGTGCAATACGAGGCTATCGAAGTGGTGGTGTACCGCGTGCGCAAAAAACTCGCAGGCACCGGCGTGGCCC
TGATGACGCTGCGCGGCCTGGGCTACCTGCTCAAGCCAGAGACATGA

Upstream 100 bases:

>100_bases
ATGCGCGCGCAAGCTGTCAAACGGCTGTCCACGGCACCAGGGTTAACACCGAGATCCGCGCGCCAACCGCCACCCGCCGC
AAACGCGTTCTAATCCGCGG

Downstream 100 bases:

>100_bases
AACAGCCCGTGAGTCGCTGCGCGCCTTCCCCCCCCAGGCGGGCGATGCCGCAGGCCCGGCCGGGCCCGCTGCGCGGCGCG
CGCTGGCATGGTTTGCGCCA

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MQLLLVEDDATMQATLQRSLARRGMAVTALADGRAALAEWRAHPPDAVVLDLTLPGLDGLQVLQQARAGGLRTPVLLLTA
RGTVGDRVLGLNAGADDYLPKPFDLDELEARLRALLRRSGGDTADDKQASNALVMGALRYEKESGAIYLHDAPMDLTPRE
LALLRTLLTQPGRAVAKERLYELVFPGQSEVQYEAIEVVVYRVRKKLAGTGVALMTLRGLGYLLKPET

Sequences:

>Translated_228_residues
MQLLLVEDDATMQATLQRSLARRGMAVTALADGRAALAEWRAHPPDAVVLDLTLPGLDGLQVLQQARAGGLRTPVLLLTA
RGTVGDRVLGLNAGADDYLPKPFDLDELEARLRALLRRSGGDTADDKQASNALVMGALRYEKESGAIYLHDAPMDLTPRE
LALLRTLLTQPGRAVAKERLYELVFPGQSEVQYEAIEVVVYRVRKKLAGTGVALMTLRGLGYLLKPET
>Mature_228_residues
MQLLLVEDDATMQATLQRSLARRGMAVTALADGRAALAEWRAHPPDAVVLDLTLPGLDGLQVLQQARAGGLRTPVLLLTA
RGTVGDRVLGLNAGADDYLPKPFDLDELEARLRALLRRSGGDTADDKQASNALVMGALRYEKESGAIYLHDAPMDLTPRE
LALLRTLLTQPGRAVAKERLYELVFPGQSEVQYEAIEVVVYRVRKKLAGTGVALMTLRGLGYLLKPET

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=40.1785714285714, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=37.0535714285714, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=32.15859030837, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=31.304347826087, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=32.5892857142857, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=34.070796460177, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=31.5555555555556, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=32, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=32.4561403508772, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=32.3008849557522, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=36.0169491525424, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=29.1304347826087, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=38.3177570093458, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790299, Length=134, Percent_Identity=32.8358208955224, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=25.5506607929515, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=36.2068965517241, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=119, Percent_Identity=32.7731092436975, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=30.7692307692308, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24766; Mature: 24766

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLLVEDDATMQATLQRSLARRGMAVTALADGRAALAEWRAHPPDAVVLDLTLPGLDGL
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCHHH
QVLQQARAGGLRTPVLLLTARGTVGDRVLGLNAGADDYLPKPFDLDELEARLRALLRRSG
HHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GDTADDKQASNALVMGALRYEKESGAIYLHDAPMDLTPRELALLRTLLTQPGRAVAKERL
CCCCCHHHHCCCEEEHEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
YELVFPGQSEVQYEAIEVVVYRVRKKLAGTGVALMTLRGLGYLLKPET
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEECCCC
>Mature Secondary Structure
MQLLLVEDDATMQATLQRSLARRGMAVTALADGRAALAEWRAHPPDAVVLDLTLPGLDGL
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCHHH
QVLQQARAGGLRTPVLLLTARGTVGDRVLGLNAGADDYLPKPFDLDELEARLRALLRRSG
HHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GDTADDKQASNALVMGALRYEKESGAIYLHDAPMDLTPRELALLRTLLTQPGRAVAKERL
CCCCCHHHHCCCEEEHEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
YELVFPGQSEVQYEAIEVVVYRVRKKLAGTGVALMTLRGLGYLLKPET
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]