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The map label for this gene is qseC [H]

Identifier: 222111265

GI number: 222111265

Start: 2226112

End: 2227515

Strand: Direct

Name: qseC [H]

Synonym: Dtpsy_2074

Alternate gene names: 222111265

Gene position: 2226112-2227515 (Clockwise)

Preceding gene: 222111264

Following gene: 222111266

Centisome position: 58.63

GC content: 70.3

Gene sequence:

>1404_bases
ATGACGCGCCCGCAGTCGCTGCGCCGCCAATTGCTCGTGGGCATCCTGCTGCCCACGCTGCTCTTCGTGGGCGTGAACAC
CTACAGCCTGCACCGCCAGGCGCTGGCCGCGCTGCACACTGCCTATGACCGCACGCTGCTGGCTTCGGCCAAGACCATCA
GCGAGCAGCTGGACGTGCGCGGCTGGGACGACATGGCCGAGCTGCGCGCCATCGTGCCTTACGCGGCGCTGGAGGCCTTC
GAGGCCGACAACCAGAGCCGCATGTTCTACCGCGTGTCCAACCTGCGCGGCGACTTGGTTTCCGGCTTTGCCGAACTACC
CGCCTGGCACGGCACCATCCCGCAGCGCCCGCCCTATGCGGCGCTCGTGGACTTCTATGACGACCGTTTTCGCGATCAGC
CCGTGCGCGTGGCCGTGCTGCTGCAGCCCGTGGCCAGCAGCGAGGGCCGCGGCATGGCCGTGATCCAGGTGGCGGAAACA
CTGGAGCTGCGCGAAGCGGCGGCCCTGCAGATCCTGCACACCACGCTGGCACGCCAGGCGCTGCTGCTGGCGCTCATCGC
GGGCATCGTGGTGCTGGTGGTGCAGCGCGCCACGCAACCGGTGCGCCAACTAAGCAGCGACCTGCAGGCCCGTACCGAAG
GCGACCTGGCCCCCCTTGCCGCCCCCGCCGCGCCGCGCGAACTGCAGCCGCTGATCGACGCCACCAACGCGGTCATGCAG
CGCCTGTCGCGCCTGCTCGCCCACCAGCAGCGCTTCGTGCGCGACGCGTCACACCAGCTGCGCACGCCGCTGGCCGTGCT
CAAGACGCAGGTGCAGTCCGCCCTGCGCGGCGACCTGCCGCCCACGCAGGCGCTGCGGGAGATTGGAGACACCGTGGACC
GCGCCACGCAGCTGGCCAACCAGATGCTGGCGCTGGCCAAAGTGGAGCAGCTGCGCCAGCAGGGCGAGGTGCCCGTGACG
CGGCTGGACACAGTGCTGCGCGAGATGGCGCTCGAGCTTTCTCCGCTGATCGCACAGGGCGACCTGGACTTCGGCATCAC
CACCGACACCGCGCCCATTCGCGCGCATGAATGGATGCTGCGCGAGCTGTGCCGCAACTTGCTGCACAACGCCATACGCC
ATGCGCCGCCCGGCACCGAACTCGCCGTCACGCTGCACAGCGATGACCATGAGGCCGTCCTCACCCTGGCCGACGCGGGC
CCCGGCATCGACGAAGAACTCGCGGCGCGGCTGTTCCAACCGTTTTCGGCCGGCGACGTGCGCACGGGTTCGGGCCTGGG
CCTGGCGATTTGCCAGGAGATCGTGCACGCGCTGGGCGGCAGCATCACCCTCGCCAATCGCCAGGCGGACGGCCGCGTGC
TGGGCCTGGACGCCGTGGTGCGGCTGCCACTGGCCGACGCCTGA

Upstream 100 bases:

>100_bases
CGCGCTGGCATGGTTTGCGCCACCGCCACCGCCACCGGACAGGAGCCGGCGCGCCTGTGCGCCAGGCTCCCCACCACGCA
CAACGCAGCCGGGTGGCGGC

Downstream 100 bases:

>100_bases
ACCGTTTTTCACGCACGCCGCCCCAGGCAAAATCACGCAGATGACGACACCACCCGATGCAATGCGCCTGGACAAATGGC
TGTGGTGCGCGCGCTTTTAC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTRPQSLRRQLLVGILLPTLLFVGVNTYSLHRQALAALHTAYDRTLLASAKTISEQLDVRGWDDMAELRAIVPYAALEAF
EADNQSRMFYRVSNLRGDLVSGFAELPAWHGTIPQRPPYAALVDFYDDRFRDQPVRVAVLLQPVASSEGRGMAVIQVAET
LELREAAALQILHTTLARQALLLALIAGIVVLVVQRATQPVRQLSSDLQARTEGDLAPLAAPAAPRELQPLIDATNAVMQ
RLSRLLAHQQRFVRDASHQLRTPLAVLKTQVQSALRGDLPPTQALREIGDTVDRATQLANQMLALAKVEQLRQQGEVPVT
RLDTVLREMALELSPLIAQGDLDFGITTDTAPIRAHEWMLRELCRNLLHNAIRHAPPGTELAVTLHSDDHEAVLTLADAG
PGIDEELAARLFQPFSAGDVRTGSGLGLAICQEIVHALGGSITLANRQADGRVLGLDAVVRLPLADA

Sequences:

>Translated_467_residues
MTRPQSLRRQLLVGILLPTLLFVGVNTYSLHRQALAALHTAYDRTLLASAKTISEQLDVRGWDDMAELRAIVPYAALEAF
EADNQSRMFYRVSNLRGDLVSGFAELPAWHGTIPQRPPYAALVDFYDDRFRDQPVRVAVLLQPVASSEGRGMAVIQVAET
LELREAAALQILHTTLARQALLLALIAGIVVLVVQRATQPVRQLSSDLQARTEGDLAPLAAPAAPRELQPLIDATNAVMQ
RLSRLLAHQQRFVRDASHQLRTPLAVLKTQVQSALRGDLPPTQALREIGDTVDRATQLANQMLALAKVEQLRQQGEVPVT
RLDTVLREMALELSPLIAQGDLDFGITTDTAPIRAHEWMLRELCRNLLHNAIRHAPPGTELAVTLHSDDHEAVLTLADAG
PGIDEELAARLFQPFSAGDVRTGSGLGLAICQEIVHALGGSITLANRQADGRVLGLDAVVRLPLADA
>Mature_466_residues
TRPQSLRRQLLVGILLPTLLFVGVNTYSLHRQALAALHTAYDRTLLASAKTISEQLDVRGWDDMAELRAIVPYAALEAFE
ADNQSRMFYRVSNLRGDLVSGFAELPAWHGTIPQRPPYAALVDFYDDRFRDQPVRVAVLLQPVASSEGRGMAVIQVAETL
ELREAAALQILHTTLARQALLLALIAGIVVLVVQRATQPVRQLSSDLQARTEGDLAPLAAPAAPRELQPLIDATNAVMQR
LSRLLAHQQRFVRDASHQLRTPLAVLKTQVQSALRGDLPPTQALREIGDTVDRATQLANQMLALAKVEQLRQQGEVPVTR
LDTVLREMALELSPLIAQGDLDFGITTDTAPIRAHEWMLRELCRNLLHNAIRHAPPGTELAVTLHSDDHEAVLTLADAGP
GIDEELAARLFQPFSAGDVRTGSGLGLAICQEIVHALGGSITLANRQADGRVLGLDAVVRLPLADA

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=327, Percent_Identity=30.5810397553517, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1790551, Length=309, Percent_Identity=31.7152103559871, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786783, Length=329, Percent_Identity=25.531914893617, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=28.9855072463768, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788279, Length=281, Percent_Identity=24.9110320284698, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786600, Length=212, Percent_Identity=31.1320754716981, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=29.2792792792793, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790346, Length=275, Percent_Identity=25.8181818181818, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=24.4019138755981, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=375, Percent_Identity=28, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=23.6, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=310, Percent_Identity=24.8387096774194, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=28.0701754385965, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789808, Length=300, Percent_Identity=25.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=199, Percent_Identity=25.6281407035176, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=25.6410256410256, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50935; Mature: 50804

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPQSLRRQLLVGILLPTLLFVGVNTYSLHRQALAALHTAYDRTLLASAKTISEQLDVR
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GWDDMAELRAIVPYAALEAFEADNQSRMFYRVSNLRGDLVSGFAELPAWHGTIPQRPPYA
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCHH
ALVDFYDDRFRDQPVRVAVLLQPVASSEGRGMAVIQVAETLELREAAALQILHTTLARQA
HHHHHHHHHCCCCCEEEEEEEEHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LLLALIAGIVVLVVQRATQPVRQLSSDLQARTEGDLAPLAAPAAPRELQPLIDATNAVMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RLSRLLAHQQRFVRDASHQLRTPLAVLKTQVQSALRGDLPPTQALREIGDTVDRATQLAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QMLALAKVEQLRQQGEVPVTRLDTVLREMALELSPLIAQGDLDFGITTDTAPIRAHEWML
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
RELCRNLLHNAIRHAPPGTELAVTLHSDDHEAVLTLADAGPGIDEELAARLFQPFSAGDV
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCC
RTGSGLGLAICQEIVHALGGSITLANRQADGRVLGLDAVVRLPLADA
CCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEECHHHHHHCCCCCC
>Mature Secondary Structure 
TRPQSLRRQLLVGILLPTLLFVGVNTYSLHRQALAALHTAYDRTLLASAKTISEQLDVR
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GWDDMAELRAIVPYAALEAFEADNQSRMFYRVSNLRGDLVSGFAELPAWHGTIPQRPPYA
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCHH
ALVDFYDDRFRDQPVRVAVLLQPVASSEGRGMAVIQVAETLELREAAALQILHTTLARQA
HHHHHHHHHCCCCCEEEEEEEEHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LLLALIAGIVVLVVQRATQPVRQLSSDLQARTEGDLAPLAAPAAPRELQPLIDATNAVMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RLSRLLAHQQRFVRDASHQLRTPLAVLKTQVQSALRGDLPPTQALREIGDTVDRATQLAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QMLALAKVEQLRQQGEVPVTRLDTVLREMALELSPLIAQGDLDFGITTDTAPIRAHEWML
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
RELCRNLLHNAIRHAPPGTELAVTLHSDDHEAVLTLADAGPGIDEELAARLFQPFSAGDV
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCC
RTGSGLGLAICQEIVHALGGSITLANRQADGRVLGLDAVVRLPLADA
CCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEECHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]