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The map label for this gene is argK [C]

Identifier: 222111043

GI number: 222111043

Start: 1970417

End: 1971445

Strand: Direct

Name: argK [C]

Synonym: Dtpsy_1850

Alternate gene names: 222111043

Gene position: 1970417-1971445 (Clockwise)

Preceding gene: 222111042

Following gene: 222111044

Centisome position: 51.9

GC content: 68.32

Gene sequence:

>1029_bases
GTGACCCCCCAGCAGCTGCAAGAAGGCATCCTGCACGGCGCGCCCGCCGTGCGGCGCCGCGCCATGGCCAAGGCCATCAC
GCTGCTGGAATCCACGCGGGCCGACCATCGCACGCAGGGCGACGAACTGCTCACCGCGCTGCTGCCGCACACGGGCCGGG
CGTTTCGCCTCGGCATCAGCGGCGTGCCTGGCGTGGGCAAGAGCACCTTCATCGAAGCCTTGGGCCTGCACCTGATCGCA
CAAGGCCTGAAGGTGGCGGTGCTGGCCATCGACCCGTCATCCACCGTCTCGGGCGGCTCCATCCTCGGTGACAAGACGCG
CATGGAGCACCTGTCGGTCCACCCCGATGCCTACATCCGCCCCAGCCCGTCCAGCGGCACGCTGGGCGGCGTGGCCGAGA
AGACGCGCGAGGCCATGCTGGTGTGCGAGGCTGCGGGCTATGACGTGGTCATCATCGAGACCGTGGGCGTGGGCCAGAGC
GAGATCGCCGTGCAGGGCATGACCGACATGTTCTGCGTGCTGCAGTTGCCCAACGCGGGCGACGACCTGCAGGCCATCAA
GAAGGGTGTGATGGAGCTGGCCGACCTGGTGGTCATCAACAAGGCCGACATCGACCCGCACGCCGCCACACGCGCGCAGG
CGCAGATCACTTCCAGCCTGCGCCTGCTGTCCATGCATGGCAACCCCGAGCATGCGCACCACGACGAATCCCTGTGGACG
CCGAAGGTCATCACGCTCAGCGCGCTGAAAGGCGAGGGGGTGGATGGCTTCTGGGCCGCGGTGCAGGAGTTCCGCCGCCT
GCAGACGGCCAACGGCCGCCTGGCCGCGCGGCGCGAGCGGCAATCACTGGCGTGGATGTGGGAGCGCATCGACGCAGGCC
TGAAGCAGGCCTTCCGCCAGCACCCGCAGGTGCGCGAGCTGCTGCCCCGCCTGCAGCAGGACGTGGCCGCGGGGCGCGTA
GCGGCTTCCACTGCAGCACGAAATTTGCTTGCGGCGCAATCTGGACAAGCGCTGCAAGCTACTATTTAA

Upstream 100 bases:

>100_bases
TCCTCTACGGTGCAGGCGTCAAGGGCGTCTATGGTCCCGGCACGCCGATCCCGGCCAGCGCCAAGGATGTGCTGGAGCAA
ATCAAGAAGGCGCAGGCGCA

Downstream 100 bases:

>100_bases
ATAGCACTTCACTGAAAGAGCGACCATGCAAGACATCCTGGATCAACTGGAGAAAAAGCGCGAACTCGCCCGCCTGGGCG
GTGGCCAGAAGCGCATCGAC

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTPQQLQEGILHGAPAVRRRAMAKAITLLESTRADHRTQGDELLTALLPHTGRAFRLGISGVPGVGKSTFIEALGLHLIA
QGLKVAVLAIDPSSTVSGGSILGDKTRMEHLSVHPDAYIRPSPSSGTLGGVAEKTREAMLVCEAAGYDVVIIETVGVGQS
EIAVQGMTDMFCVLQLPNAGDDLQAIKKGVMELADLVVINKADIDPHAATRAQAQITSSLRLLSMHGNPEHAHHDESLWT
PKVITLSALKGEGVDGFWAAVQEFRRLQTANGRLAARRERQSLAWMWERIDAGLKQAFRQHPQVRELLPRLQQDVAAGRV
AASTAARNLLAAQSGQALQATI

Sequences:

>Translated_342_residues
MTPQQLQEGILHGAPAVRRRAMAKAITLLESTRADHRTQGDELLTALLPHTGRAFRLGISGVPGVGKSTFIEALGLHLIA
QGLKVAVLAIDPSSTVSGGSILGDKTRMEHLSVHPDAYIRPSPSSGTLGGVAEKTREAMLVCEAAGYDVVIIETVGVGQS
EIAVQGMTDMFCVLQLPNAGDDLQAIKKGVMELADLVVINKADIDPHAATRAQAQITSSLRLLSMHGNPEHAHHDESLWT
PKVITLSALKGEGVDGFWAAVQEFRRLQTANGRLAARRERQSLAWMWERIDAGLKQAFRQHPQVRELLPRLQQDVAAGRV
AASTAARNLLAAQSGQALQATI
>Mature_341_residues
TPQQLQEGILHGAPAVRRRAMAKAITLLESTRADHRTQGDELLTALLPHTGRAFRLGISGVPGVGKSTFIEALGLHLIAQ
GLKVAVLAIDPSSTVSGGSILGDKTRMEHLSVHPDAYIRPSPSSGTLGGVAEKTREAMLVCEAAGYDVVIIETVGVGQSE
IAVQGMTDMFCVLQLPNAGDDLQAIKKGVMELADLVVINKADIDPHAATRAQAQITSSLRLLSMHGNPEHAHHDESLWTP
KVITLSALKGEGVDGFWAAVQEFRRLQTANGRLAARRERQSLAWMWERIDAGLKQAFRQHPQVRELLPRLQQDVAAGRVA
ASTAARNLLAAQSGQALQATI

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=339, Percent_Identity=46.9026548672566, Blast_Score=287, Evalue=9e-78,
Organism=Escherichia coli, GI1789285, Length=269, Percent_Identity=52.4163568773234, Blast_Score=273, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI71994271, Length=339, Percent_Identity=43.0678466076696, Blast_Score=264, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI71994275, Length=278, Percent_Identity=45.6834532374101, Blast_Score=247, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 36653; Mature: 36521

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQQLQEGILHGAPAVRRRAMAKAITLLESTRADHRTQGDELLTALLPHTGRAFRLGIS
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHCCCCCEEEEECC
GVPGVGKSTFIEALGLHLIAQGLKVAVLAIDPSSTVSGGSILGDKTRMEHLSVHPDAYIR
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHEECCCCCEEC
PSPSSGTLGGVAEKTREAMLVCEAAGYDVVIIETVGVGQSEIAVQGMTDMFCVLQLPNAG
CCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEEEECCCCHHHHHHCCHHEEEEEECCCCC
DDLQAIKKGVMELADLVVINKADIDPHAATRAQAQITSSLRLLSMHGNPEHAHHDESLWT
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCC
PKVITLSALKGEGVDGFWAAVQEFRRLQTANGRLAARRERQSLAWMWERIDAGLKQAFRQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HPQVRELLPRLQQDVAAGRVAASTAARNLLAAQSGQALQATI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
TPQQLQEGILHGAPAVRRRAMAKAITLLESTRADHRTQGDELLTALLPHTGRAFRLGIS
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHCCCCCEEEEECC
GVPGVGKSTFIEALGLHLIAQGLKVAVLAIDPSSTVSGGSILGDKTRMEHLSVHPDAYIR
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHEECCCCCEEC
PSPSSGTLGGVAEKTREAMLVCEAAGYDVVIIETVGVGQSEIAVQGMTDMFCVLQLPNAG
CCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEEEECCCCHHHHHHCCHHEEEEEECCCCC
DDLQAIKKGVMELADLVVINKADIDPHAATRAQAQITSSLRLLSMHGNPEHAHHDESLWT
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCC
PKVITLSALKGEGVDGFWAAVQEFRRLQTANGRLAARRERQSLAWMWERIDAGLKQAFRQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HPQVRELLPRLQQDVAAGRVAASTAARNLLAAQSGQALQATI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]