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The map label for this gene is mauR [H]

Identifier: 222111007

GI number: 222111007

Start: 1929789

End: 1930700

Strand: Direct

Name: mauR [H]

Synonym: Dtpsy_1814

Alternate gene names: 222111007

Gene position: 1929789-1930700 (Clockwise)

Preceding gene: 222111001

Following gene: 222111013

Centisome position: 50.83

GC content: 69.19

Gene sequence:

>912_bases
ATGGATTGGGACAATTTGCGCTACTTCCTGGAGCTGGCGCGCACCGGCACGCTGGCAGGGGCCGCGCGCCGCACGGGCGT
GGAACACACGACAGTGGCGCGGCGCATCCAGGCGCTGGAAAAACAGATGGGTGCGCCGCTGTTCGCCCGCGAGGCAGCGG
GACATCGGCTGACGGAAACCGGCCGCCACCTGCTGCCCGCCGTCGAGGCCATGGAGGCCGCCGTGCTGGGGGTGGAGCGC
GCATCGCCCGCCAACTCCCCGGGCGCGGGCCCCTCGGGACTGGTGCGCGTGGGTGCCACCGAGGGTTTTGGCACGGTGGT
GCTGGCGCCGCATCTGGCGCGGCTCACACAGAAGCACCCGCACTTGTCCATCGACCTGCTGGCCCTGCCGCGCATGCTGC
ACCTGAGCCGGCGCGAGGCGGACATCGTGATCTCCCTGGAGCGGCCCAAGCGCGGCTCGGTGATCGTCACCAAACTCGCC
GACTACACCCTGCGTCTCTACGGCCAGCGCGAGTACCTGGCGCGCAGACCGCTGGTGGCCAAGCGTGAAGACCTGCGCCA
CCACGCCTTCATCAGCTACGTGGACGATCTGCTGTTCACAAAAGAGCTGCAGTTCATCGACCAACTCTACCCGCCCGAGC
GTTTTGCGCTGCGCAGCACCAGCATCACCGCGCAGTACGAGGCCGTGCGCGCCGGCGCGGGCCTGGCCGTGCTGCCCGCA
TTCCTGGCCGACCGTGACCCCGTACTTGCGCGCGTGCTGCCCCACGAGGCCGAGTTCACACGCACCTTCTGGATGAGCAT
GCCGGCCGAGTCCAAGCACTTGGCGCGCATGCAGGCGGTGTGGGCCTTCCTGAAAGACGTGGGCCAGCGCGAGGCGGCAT
CGCTGGTCCCACGGAAACCAGCGGCAGGCTAG

Upstream 100 bases:

>100_bases
GACTTGGCATGGCTGCATCGTAGTTGTGCGAAATTGCGTAGGCAATAGACAATCACGCACCTTGGCTTTGCAAATTTGCA
CATCACCGCAGAGGAGCCGT

Downstream 100 bases:

>100_bases
GGCACGCTGCGGCATACAGAAAAAGGCCCCCGCATGCGGGGGCCTTGCGGACCAGGGGATCAGCGAGGATCAACCCTGTT
CTTTGTTCTTGCCCGACGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDWDNLRYFLELARTGTLAGAARRTGVEHTTVARRIQALEKQMGAPLFAREAAGHRLTETGRHLLPAVEAMEAAVLGVER
ASPANSPGAGPSGLVRVGATEGFGTVVLAPHLARLTQKHPHLSIDLLALPRMLHLSRREADIVISLERPKRGSVIVTKLA
DYTLRLYGQREYLARRPLVAKREDLRHHAFISYVDDLLFTKELQFIDQLYPPERFALRSTSITAQYEAVRAGAGLAVLPA
FLADRDPVLARVLPHEAEFTRTFWMSMPAESKHLARMQAVWAFLKDVGQREAASLVPRKPAAG

Sequences:

>Translated_303_residues
MDWDNLRYFLELARTGTLAGAARRTGVEHTTVARRIQALEKQMGAPLFAREAAGHRLTETGRHLLPAVEAMEAAVLGVER
ASPANSPGAGPSGLVRVGATEGFGTVVLAPHLARLTQKHPHLSIDLLALPRMLHLSRREADIVISLERPKRGSVIVTKLA
DYTLRLYGQREYLARRPLVAKREDLRHHAFISYVDDLLFTKELQFIDQLYPPERFALRSTSITAQYEAVRAGAGLAVLPA
FLADRDPVLARVLPHEAEFTRTFWMSMPAESKHLARMQAVWAFLKDVGQREAASLVPRKPAAG
>Mature_303_residues
MDWDNLRYFLELARTGTLAGAARRTGVEHTTVARRIQALEKQMGAPLFAREAAGHRLTETGRHLLPAVEAMEAAVLGVER
ASPANSPGAGPSGLVRVGATEGFGTVVLAPHLARLTQKHPHLSIDLLALPRMLHLSRREADIVISLERPKRGSVIVTKLA
DYTLRLYGQREYLARRPLVAKREDLRHHAFISYVDDLLFTKELQFIDQLYPPERFALRSTSITAQYEAVRAGAGLAVLPA
FLADRDPVLARVLPHEAEFTRTFWMSMPAESKHLARMQAVWAFLKDVGQREAASLVPRKPAAG

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=198, Percent_Identity=26.2626262626263, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994962, Length=175, Percent_Identity=29.7142857142857, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=21.4285714285714, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33585; Mature: 33585

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWDNLRYFLELARTGTLAGAARRTGVEHTTVARRIQALEKQMGAPLFAREAAGHRLTET
CCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHH
GRHLLPAVEAMEAAVLGVERASPANSPGAGPSGLVRVGATEGFGTVVLAPHLARLTQKHP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCEEHHHHHHHHHHCCC
HLSIDLLALPRMLHLSRREADIVISLERPKRGSVIVTKLADYTLRLYGQREYLARRPLVA
CCEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHCCHHHHHHCCCHH
KREDLRHHAFISYVDDLLFTKELQFIDQLYPPERFALRSTSITAQYEAVRAGAGLAVLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHCCCHHHHHH
FLADRDPVLARVLPHEAEFTRTFWMSMPAESKHLARMQAVWAFLKDVGQREAASLVPRKP
HHCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAG
CCC
>Mature Secondary Structure
MDWDNLRYFLELARTGTLAGAARRTGVEHTTVARRIQALEKQMGAPLFAREAAGHRLTET
CCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHH
GRHLLPAVEAMEAAVLGVERASPANSPGAGPSGLVRVGATEGFGTVVLAPHLARLTQKHP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCEEHHHHHHHHHHCCC
HLSIDLLALPRMLHLSRREADIVISLERPKRGSVIVTKLADYTLRLYGQREYLARRPLVA
CCEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHCCHHHHHHCCCHH
KREDLRHHAFISYVDDLLFTKELQFIDQLYPPERFALRSTSITAQYEAVRAGAGLAVLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHCCCHHHHHH
FLADRDPVLARVLPHEAEFTRTFWMSMPAESKHLARMQAVWAFLKDVGQREAASLVPRKP
HHCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]