Click here to switch to the map view.

The map label for this gene is lpsJ [H]

Identifier: 222110956

GI number: 222110956

Start: 1874470

End: 1875108

Strand: Direct

Name: lpsJ [H]

Synonym: Dtpsy_1763

Alternate gene names: 222110956

Gene position: 1874470-1875108 (Clockwise)

Preceding gene: 222110955

Following gene: 222110957

Centisome position: 49.37

GC content: 64.32

Gene sequence:

>639_bases
ATGCCGTGGACCCAAGACCAGATGGCGGCCCGCGCCGCGCAAGAACTCGAAGACGGCTTCTACGTCAACTTAGGGATAGG
CATTCCCACGCTGGTGGCCAACTTCACCGGCGATAAAGAGGTGTGGCTGCAGTCGGAGAACGGCATGCTGGGCATCGGTG
CCTTTCCCACCGAGGACAAGGTGGATGCCGACCTCATCAACGCCGGCAAGCAGACCGTCACCACCATCCCCGGTTCGTCC
ATCTTCAGTTCGGACCAGTCGTTCGCGATGATCCGCGGCGGCAAGATCAACCTGTCCATCCTGGGCGCCATGCAGGTCAG
CGAGAAGGGCGACCTGGCCAACTGGATGATCCCCGGCAAGATGGTCAAGGGCATGGGCGGCGCCATGGACCTGGTGGCCG
GTGTCAAGCGCGTGATCGTGCTCATGGAGCATGTGGCGCGCAAGAAGGACGGCACCACCGACCTGAAGATCCTGCCGGCC
TGCACGCTGCCGCTGACGGGCGTGGGCGTGGTGGACCGCATCATCACCGACCTGGGCGTGATGGACGTCACCCCCGAAGG
CCTGAAGCTGGTGGAACTGGCGCCGGGCGTGAGCTTCGAGGACATCCAGTCCAAGACCGGCGTGCCGCTGCTGCGCTGA

Upstream 100 bases:

>100_bases
CCACCTGCCCGGCATCTACGTGCACCGCATCGTGCACAACCCGAACCCCGAGAAGCGCATCGAGAAGCGCACCATCACCG
AGAAAGCAGGAGCCTGAACC

Downstream 100 bases:

>100_bases
GGGCAGGCACCGCCAGGCCGCATGCGCATGCACGGCGGGGGCGCGGGGCCAAAACTACGGGCCGGGTGGGATCACCCGGC
TTTTTTGTCTTTTTGCGCAA

Product: 3-oxoacid CoA-transferase subunit B

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MPWTQDQMAARAAQELEDGFYVNLGIGIPTLVANFTGDKEVWLQSENGMLGIGAFPTEDKVDADLINAGKQTVTTIPGSS
IFSSDQSFAMIRGGKINLSILGAMQVSEKGDLANWMIPGKMVKGMGGAMDLVAGVKRVIVLMEHVARKKDGTTDLKILPA
CTLPLTGVGVVDRIITDLGVMDVTPEGLKLVELAPGVSFEDIQSKTGVPLLR

Sequences:

>Translated_212_residues
MPWTQDQMAARAAQELEDGFYVNLGIGIPTLVANFTGDKEVWLQSENGMLGIGAFPTEDKVDADLINAGKQTVTTIPGSS
IFSSDQSFAMIRGGKINLSILGAMQVSEKGDLANWMIPGKMVKGMGGAMDLVAGVKRVIVLMEHVARKKDGTTDLKILPA
CTLPLTGVGVVDRIITDLGVMDVTPEGLKLVELAPGVSFEDIQSKTGVPLLR
>Mature_211_residues
PWTQDQMAARAAQELEDGFYVNLGIGIPTLVANFTGDKEVWLQSENGMLGIGAFPTEDKVDADLINAGKQTVTTIPGSSI
FSSDQSFAMIRGGKINLSILGAMQVSEKGDLANWMIPGKMVKGMGGAMDLVAGVKRVIVLMEHVARKKDGTTDLKILPAC
TLPLTGVGVVDRIITDLGVMDVTPEGLKLVELAPGVSFEDIQSKTGVPLLR

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=207, Percent_Identity=58.4541062801932, Blast_Score=234, Evalue=5e-62,
Organism=Homo sapiens, GI11545841, Length=201, Percent_Identity=62.1890547263682, Blast_Score=229, Evalue=1e-60,
Organism=Escherichia coli, GI1788552, Length=203, Percent_Identity=48.2758620689655, Blast_Score=182, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17531517, Length=208, Percent_Identity=55.2884615384615, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21358325, Length=206, Percent_Identity=58.7378640776699, Blast_Score=226, Evalue=9e-60,
Organism=Drosophila melanogaster, GI24655794, Length=206, Percent_Identity=58.7378640776699, Blast_Score=225, Evalue=2e-59,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 22515; Mature: 22383

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWTQDQMAARAAQELEDGFYVNLGIGIPTLVANFTGDKEVWLQSENGMLGIGAFPTEDK
CCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCC
VDADLINAGKQTVTTIPGSSIFSSDQSFAMIRGGKINLSILGAMQVSEKGDLANWMIPGK
CCHHHHHCCCCEEEECCCCHHHCCCCCEEEEECCEEEEEEEEEEEECCCCCCCEEECCHH
MVKGMGGAMDLVAGVKRVIVLMEHVARKKDGTTDLKILPACTLPLTGVGVVDRIITDLGV
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCC
MDVTPEGLKLVELAPGVSFEDIQSKTGVPLLR
CCCCCCCCEEEEECCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
PWTQDQMAARAAQELEDGFYVNLGIGIPTLVANFTGDKEVWLQSENGMLGIGAFPTEDK
CCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCC
VDADLINAGKQTVTTIPGSSIFSSDQSFAMIRGGKINLSILGAMQVSEKGDLANWMIPGK
CCHHHHHCCCCEEEECCCCHHHCCCCCEEEEECCEEEEEEEEEEEECCCCCCCEEECCHH
MVKGMGGAMDLVAGVKRVIVLMEHVARKKDGTTDLKILPACTLPLTGVGVVDRIITDLGV
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCC
MDVTPEGLKLVELAPGVSFEDIQSKTGVPLLR
CCCCCCCCEEEEECCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134 [H]