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The map label for this gene is acoR [H]

Identifier: 222110884

GI number: 222110884

Start: 1793270

End: 1795273

Strand: Direct

Name: acoR [H]

Synonym: Dtpsy_1691

Alternate gene names: 222110884

Gene position: 1793270-1795273 (Clockwise)

Preceding gene: 222110883

Following gene: 222110889

Centisome position: 47.23

GC content: 72.41

Gene sequence:

>2004_bases
ATGCACCGCACCGCAACGCCCGGCGCGCATCCTTCCGCGGGTGCCGCGCTGGCGCTGACCACGGCAGGCGTCGTCGCCCA
GGCCCACGCCCGCTCGCAGTCGTTCGGGCTGCAGCCCCATGAGCAGGCCGACCTGCACCTGCTGGACCGCCAGACCCTGG
CCTGGACCGTGGCACGCAACGAGGCCCTGTGCGCCCATGCGCGGCCCGTCATGGAAACCCTGGCGCAGCAGCTGCGCGGC
ACGCAGAGCATGGTGATGCTGACCGACGCGCAGGGGGTGATCCTGCATGCCGAGGGCGATGATGCCTTCCTGGACCGCGC
CGGCCGCGTGGCCCTGCAGCCCGGTGCGGGCTGGTCGGAGCGCAGCAAGGGCACCAACGCCATTGGTACGGCGTTGGCCC
TGGGCGATGCGGTGCAGATCAACGGGCGCCAGCATTACCTGGAAGCCAACCAGTTCCTCACCTGTTCATGCGCTCCCATC
CTGGATCCGCAGGGGCAGATCCTCGGCGCGCTGGACGTGAGCGGCGACCGCCGCGGCCACAGCGCCCACACGCTGGCGCT
GGTGCGCATGTCCGCCGCGATGGTGGAGAACCACCTCTTCGGCAAGGTGTACGAGGATGCCGTGCGCCTGCGCTTTCATG
CGCGCGCGGAGTTCCTGTGCACGCTCATGGAAGGGCTGGCGGCGTTCACCCCGCAGGGGCGCTTTCTGGCGGCCAACCGC
AGCGCGCAGTTCCAGCTGGGGTTGTCGGGACCGGCGCTGGCGGCACACACCTTCACCTCGCTGTTCGGCCTGTCGATGGG
CGCGCTGCTGGAGCATGCGCGCCGCTCGGTGCCCACGCTGCTTGCGCTGCAACTGCCGGCAGGCGTGTCGGTGCACGCAC
AGGTGGAGTTTGCGCCACGCGGCGGCGTCACGCTGCCGGTGTGCCCGGACGGCCCGGCCGCGGCCCCGCCGCCGCGCGCG
CGACCCGCCGCGGCGCCGGGCCTGTCCAGCCTGCGCTACCTGGACACGGGCGATGCCCAGCTGGCGCAGGTGATCGAGCG
CGTCACGCGGCTGCTGGGGCGTGGCGTGCCCACGATGATCCTGGGTGAGACGGGCACCGGCAAGGAGCTGCTGGCACGTG
CCATCCATAACGACGGCCCGCGCGCGCGGGGGCCCTTCGTGGCGGTGAACTGCGCGTCCATTCCCGAGTCGCTGATCGAG
GCCGAGTTGTTCGGCTACGAAGAGGGCGCCTTCACCGGCGCGCGGCGCAAGGGCAGCGTGGGCAAGATCGTGCAGGCGCA
CGGCGGCACGCTGTTCCTGGACGAGATTGGCGACATGCCGCTGGCCATGCAGGCGCGGCTGCTGCGCGTGCTGCAGGAGC
GCAGCGTGGCGCCTCTGGGCAGCACGCGACAGATCGAGGTGGACGTGAACGTGGTCTGCGCCACGCACCGCAACCTGCGC
GCCATGATGGCCGACGGCCAGTTCCGTGACGACCTGTACTACCGGCTGAACGGCCTGGTGGTGCGACTGCCTGCGCTGCG
CGAGCGCACGGACCTGGCGGTGATCGTGCAGCGGTTGCTGCGCGCCCAGCACGACTCTCCCGGCGCGGACAGCCCCATGC
CGGTGGCGCCCGAGGTGATGGCGTTGTTCGCCGCCCACCCCTGGCCGGGCAACCTGCGCCAGCTGTCCAACGTGCTGCGC
ACGTCGACGCTGTTGGCCGAGGGCGCGGACGCGATCACGTGCGCGCACCTGCCGGAGGACTTCCTGGAGGAATGCGAGGC
GCTGGCGCAGCAGGGCCGCGTGGTGGCGCAGGCGTTCTCTCAGCCGGCGGTGCCGCCAGCGGACGGCGCGCGCGCCGCGG
CCCCAGCCCCGGCCAGCGTGCGGCCGCTGGGCGACGTGGCGGCCCATGCGCTGCAGCAGGCACTGGATGCGCACGCGGGC
AATGTCTCCGCCGCCGCGCGCGCGTTGGGCGTGTCGCGCAACACGGTGTACCGCTACCTGCGCGCGCAGTCGTGTCGCTC
CTGA

Upstream 100 bases:

>100_bases
GCGGTTGCTGGGCTCGTCAGCGGCCGTTGATGCTATCGTCCGGTCCCAAAGCGCCGCCTGGCCGCGTGCCGTGCAGCGCA
TAGCTTGCATAGGAGACACC

Downstream 100 bases:

>100_bases
AAAAGGAGCGCTTTGCGCTGGTTGGGCGGGTGATTCAGTCGAAATTGACCTGAAAAACGCCACCGATACAGCGCGAGCAG
CTATTAAATAAAGAGCAACT

Product: gaf modulated Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MHRTATPGAHPSAGAALALTTAGVVAQAHARSQSFGLQPHEQADLHLLDRQTLAWTVARNEALCAHARPVMETLAQQLRG
TQSMVMLTDAQGVILHAEGDDAFLDRAGRVALQPGAGWSERSKGTNAIGTALALGDAVQINGRQHYLEANQFLTCSCAPI
LDPQGQILGALDVSGDRRGHSAHTLALVRMSAAMVENHLFGKVYEDAVRLRFHARAEFLCTLMEGLAAFTPQGRFLAANR
SAQFQLGLSGPALAAHTFTSLFGLSMGALLEHARRSVPTLLALQLPAGVSVHAQVEFAPRGGVTLPVCPDGPAAAPPPRA
RPAAAPGLSSLRYLDTGDAQLAQVIERVTRLLGRGVPTMILGETGTGKELLARAIHNDGPRARGPFVAVNCASIPESLIE
AELFGYEEGAFTGARRKGSVGKIVQAHGGTLFLDEIGDMPLAMQARLLRVLQERSVAPLGSTRQIEVDVNVVCATHRNLR
AMMADGQFRDDLYYRLNGLVVRLPALRERTDLAVIVQRLLRAQHDSPGADSPMPVAPEVMALFAAHPWPGNLRQLSNVLR
TSTLLAEGADAITCAHLPEDFLEECEALAQQGRVVAQAFSQPAVPPADGARAAAPAPASVRPLGDVAAHALQQALDAHAG
NVSAAARALGVSRNTVYRYLRAQSCRS

Sequences:

>Translated_667_residues
MHRTATPGAHPSAGAALALTTAGVVAQAHARSQSFGLQPHEQADLHLLDRQTLAWTVARNEALCAHARPVMETLAQQLRG
TQSMVMLTDAQGVILHAEGDDAFLDRAGRVALQPGAGWSERSKGTNAIGTALALGDAVQINGRQHYLEANQFLTCSCAPI
LDPQGQILGALDVSGDRRGHSAHTLALVRMSAAMVENHLFGKVYEDAVRLRFHARAEFLCTLMEGLAAFTPQGRFLAANR
SAQFQLGLSGPALAAHTFTSLFGLSMGALLEHARRSVPTLLALQLPAGVSVHAQVEFAPRGGVTLPVCPDGPAAAPPPRA
RPAAAPGLSSLRYLDTGDAQLAQVIERVTRLLGRGVPTMILGETGTGKELLARAIHNDGPRARGPFVAVNCASIPESLIE
AELFGYEEGAFTGARRKGSVGKIVQAHGGTLFLDEIGDMPLAMQARLLRVLQERSVAPLGSTRQIEVDVNVVCATHRNLR
AMMADGQFRDDLYYRLNGLVVRLPALRERTDLAVIVQRLLRAQHDSPGADSPMPVAPEVMALFAAHPWPGNLRQLSNVLR
TSTLLAEGADAITCAHLPEDFLEECEALAQQGRVVAQAFSQPAVPPADGARAAAPAPASVRPLGDVAAHALQQALDAHAG
NVSAAARALGVSRNTVYRYLRAQSCRS
>Mature_667_residues
MHRTATPGAHPSAGAALALTTAGVVAQAHARSQSFGLQPHEQADLHLLDRQTLAWTVARNEALCAHARPVMETLAQQLRG
TQSMVMLTDAQGVILHAEGDDAFLDRAGRVALQPGAGWSERSKGTNAIGTALALGDAVQINGRQHYLEANQFLTCSCAPI
LDPQGQILGALDVSGDRRGHSAHTLALVRMSAAMVENHLFGKVYEDAVRLRFHARAEFLCTLMEGLAAFTPQGRFLAANR
SAQFQLGLSGPALAAHTFTSLFGLSMGALLEHARRSVPTLLALQLPAGVSVHAQVEFAPRGGVTLPVCPDGPAAAPPPRA
RPAAAPGLSSLRYLDTGDAQLAQVIERVTRLLGRGVPTMILGETGTGKELLARAIHNDGPRARGPFVAVNCASIPESLIE
AELFGYEEGAFTGARRKGSVGKIVQAHGGTLFLDEIGDMPLAMQARLLRVLQERSVAPLGSTRQIEVDVNVVCATHRNLR
AMMADGQFRDDLYYRLNGLVVRLPALRERTDLAVIVQRLLRAQHDSPGADSPMPVAPEVMALFAAHPWPGNLRQLSNVLR
TSTLLAEGADAITCAHLPEDFLEECEALAQQGRVVAQAFSQPAVPPADGARAAAPAPASVRPLGDVAAHALQQALDAHAG
NVSAAARALGVSRNTVYRYLRAQSCRS

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=38.5802469135802, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1788905, Length=308, Percent_Identity=41.5584415584416, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1788550, Length=311, Percent_Identity=39.5498392282958, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786524, Length=336, Percent_Identity=40.1785714285714, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI1790299, Length=322, Percent_Identity=39.4409937888199, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1790437, Length=306, Percent_Identity=38.8888888888889, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI87082117, Length=214, Percent_Identity=48.1308411214953, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1789087, Length=231, Percent_Identity=43.7229437229437, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87082152, Length=250, Percent_Identity=41.6, Blast_Score=172, Evalue=9e-44,
Organism=Escherichia coli, GI1787583, Length=238, Percent_Identity=38.655462184874, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI87081872, Length=225, Percent_Identity=39.5555555555556, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI87081858, Length=620, Percent_Identity=22.258064516129, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1789828, Length=257, Percent_Identity=36.5758754863813, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70676; Mature: 70676

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRTATPGAHPSAGAALALTTAGVVAQAHARSQSFGLQPHEQADLHLLDRQTLAWTVARN
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECC
EALCAHARPVMETLAQQLRGTQSMVMLTDAQGVILHAEGDDAFLDRAGRVALQPGAGWSE
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCHHHHHCCCCEEECCCCCCCC
RSKGTNAIGTALALGDAVQINGRQHYLEANQFLTCSCAPILDPQGQILGALDVSGDRRGH
CCCCCCHHHHHHHHCCEEEECCCCEEEECCCEEEEECCCCCCCCCCEEEEEECCCCCCCC
SAHTLALVRMSAAMVENHLFGKVYEDAVRLRFHARAEFLCTLMEGLAAFTPQGRFLAANR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
SAQFQLGLSGPALAAHTFTSLFGLSMGALLEHARRSVPTLLALQLPAGVSVHAQVEFAPR
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEECCC
GGVTLPVCPDGPAAAPPPRARPAAAPGLSSLRYLDTGDAQLAQVIERVTRLLGRGVPTMI
CCCEEEECCCCCCCCCCCCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCEEE
LGETGTGKELLARAIHNDGPRARGPFVAVNCASIPESLIEAELFGYEEGAFTGARRKGSV
EECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GKIVQAHGGTLFLDEIGDMPLAMQARLLRVLQERSVAPLGSTRQIEVDVNVVCATHRNLR
CCEEECCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCHH
AMMADGQFRDDLYYRLNGLVVRLPALRERTDLAVIVQRLLRAQHDSPGADSPMPVAPEVM
HHHCCCCCHHHHHHEECCEEEEECCHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
ALFAAHPWPGNLRQLSNVLRTSTLLAEGADAITCAHLPEDFLEECEALAQQGRVVAQAFS
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHC
QPAVPPADGARAAAPAPASVRPLGDVAAHALQQALDAHAGNVSAAARALGVSRNTVYRYL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHH
RAQSCRS
HHHHCCC
>Mature Secondary Structure
MHRTATPGAHPSAGAALALTTAGVVAQAHARSQSFGLQPHEQADLHLLDRQTLAWTVARN
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECC
EALCAHARPVMETLAQQLRGTQSMVMLTDAQGVILHAEGDDAFLDRAGRVALQPGAGWSE
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCHHHHHCCCCEEECCCCCCCC
RSKGTNAIGTALALGDAVQINGRQHYLEANQFLTCSCAPILDPQGQILGALDVSGDRRGH
CCCCCCHHHHHHHHCCEEEECCCCEEEECCCEEEEECCCCCCCCCCEEEEEECCCCCCCC
SAHTLALVRMSAAMVENHLFGKVYEDAVRLRFHARAEFLCTLMEGLAAFTPQGRFLAANR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
SAQFQLGLSGPALAAHTFTSLFGLSMGALLEHARRSVPTLLALQLPAGVSVHAQVEFAPR
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEECCC
GGVTLPVCPDGPAAAPPPRARPAAAPGLSSLRYLDTGDAQLAQVIERVTRLLGRGVPTMI
CCCEEEECCCCCCCCCCCCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCEEE
LGETGTGKELLARAIHNDGPRARGPFVAVNCASIPESLIEAELFGYEEGAFTGARRKGSV
EECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GKIVQAHGGTLFLDEIGDMPLAMQARLLRVLQERSVAPLGSTRQIEVDVNVVCATHRNLR
CCEEECCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCHH
AMMADGQFRDDLYYRLNGLVVRLPALRERTDLAVIVQRLLRAQHDSPGADSPMPVAPEVM
HHHCCCCCHHHHHHEECCEEEEECCHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
ALFAAHPWPGNLRQLSNVLRTSTLLAEGADAITCAHLPEDFLEECEALAQQGRVVAQAFS
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHC
QPAVPPADGARAAAPAPASVRPLGDVAAHALQQALDAHAGNVSAAARALGVSRNTVYRYL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHH
RAQSCRS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]