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The map label for this gene is phbC [H]

Identifier: 222110875

GI number: 222110875

Start: 1781948

End: 1783666

Strand: Direct

Name: phbC [H]

Synonym: Dtpsy_1681

Alternate gene names: 222110875

Gene position: 1781948-1783666 (Clockwise)

Preceding gene: 222110873

Following gene: 222110876

Centisome position: 46.94

GC content: 65.74

Gene sequence:

>1719_bases
ATGAGCACGAATTTCGACGCCAGCTGGGCCGACAGCGCCCGGCAGTTTCAGCAGATGGTGGGCGAGGGCTGGAGCCAGAT
GCTGCAGGTCCTGCAGCCCAAAGAAATGGGCGCCGCGCTGTCCATGCCAGCTGCCGGCCCGGTGGGCTTCGCACCCGACA
AGCTGGCTGCGGTGCAGCAGCGGTACCTGCAAGAGGTGCAGGCGCTGTGGAGCCACGCGCTGCATCACGACGATGCACCC
CTCAGCAACGACCGCCGGTTCGCGGGCGAGAATTGGGCGCACAACCCGTTGTCGGCGTTCTCGGTCGCGGCCTACCAGTT
GCAGGCGCATGCGCTCATGGGCCTGGCCGACGCGGTGCAGGCCGACGACAAGACCCGTGCACGCATCCGCTTCAGCGTGG
AGCAATGGCTGGCCGCCATGGCGCCCAGCAACTTCCTGGTATTCAACGCGGACGCGCAGCAAAAAGCCCTGGAAACGCAC
GGCGAGAGCATCGCCAAGGGCGTCGCCAACCTGCTGCACGACCTGGGCCAGGGGCATATCTCGATGACCGACGAGAGCCG
CTTCGAAGTGGGCCGCAACGTGGCCACTACCGAGGGCGCCGTTGTGTTCGAGAACGAGCTGTTTCAGCTGCTGGAATACA
AGCCGCTCACCCCCAAGGTGTACGAGCGGCCCTTGCTTATGGTGCCGCCGTGCATCAACAAGTACTACATCCTGGACCTG
CAGCCCGACAACTCGCTGATCCGCCATGCCGTGGCCCAGGGCCACCGCACCTTCGTGGTGAGCTGGCGCAACCCCGATGC
GTCGCTGGCGCACAAGACCTGGGACGACTACATCGACGAGGCCGTGCTCACGGCCATCGCCACCGTGCAGCAGATCGCTG
GCGCCAAGCAGATCAACGCCCTGGGCTTTTGCGTGGGCGGCACCATGCTGGCCACGGCGCTCGCGGTGCTGGCGGCGCGC
GGCGAGGAGCCTGTGGCCAGCTGCACTTTCCTGACCACGCTGATCGATTTTGCCGACACCGGGATCCTCGACGTGTTCAT
CGACGAAGGCTTCGTGCGCATGCGCGAACTGCAGATGGGGCAGGGCGGGCTCATGAAGGGCCAGGACCTGGCATCCACCT
TCAGCTTTCTGCGCCCGAACGACCTGGTGTGGAACTACGTGGTGGGCAACTACCTCAAGGGCGAGACGCCGCCGCCCTTC
GACCTGCTGTACTGGAACAGTGACAGCACCAACCTGCCTGGGCCGTACTACGCCTGGTACCTGCGCAACTTCTACCTGGA
GAACAACCTCATCCGGCCGGGGCGGCTCACCGTGTGCGGCGAGTCACTCGACCTGACCCAGGTCCAACTGCCTGTGTACA
TCTACGGCTCGCGCGAGGATCACATCGTGCCAATCGGCGCGGCCTACGCCTCCACGCAGGTATTGCCGGGGGACAAGCGT
TTCGTGATGGGCGCGTCGGGCCATATCGCGGGGGTCATCAACCCGCCCGCCAAGAAAAAGCGCAGCCACTGGCTGCGCGA
GGATGGGCAACTGCCCGCCACGCTGGATGCGTGGCTGGCTGGGGCCACCGAACTGCCCGGCAGTTGGTGGGACGACTGGT
GCGCATGGCTGCACGGCCACGCCGGTCGGCAGATCGCCGCACCCAAGGCCTATGGAAAGGCGCCGAAGTTCAAGGCCATC
GAACCCGCGCCAGGGCGCTACGTGCAGCAAAAGGCCTGA

Upstream 100 bases:

>100_bases
GAAACCCAAAGCCCTGCGAATGCGCTGCAGTTTTCCGAGGCACCGCCTGCTGGGCAACAATGGCATACGGGGCCCGCGCC
TGGGCCGCGATGGAGGCTGC

Downstream 100 bases:

>100_bases
GGCCGGCGCCGCACGCTCCCGGGGCGGCGTTGCGGCGCGCTGCGGGGTGACTACGCAATAGTCCTGACACCGGGCCGACA
GACAATGGCTACTGGCCTGC

Product: poly(r)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MSTNFDASWADSARQFQQMVGEGWSQMLQVLQPKEMGAALSMPAAGPVGFAPDKLAAVQQRYLQEVQALWSHALHHDDAP
LSNDRRFAGENWAHNPLSAFSVAAYQLQAHALMGLADAVQADDKTRARIRFSVEQWLAAMAPSNFLVFNADAQQKALETH
GESIAKGVANLLHDLGQGHISMTDESRFEVGRNVATTEGAVVFENELFQLLEYKPLTPKVYERPLLMVPPCINKYYILDL
QPDNSLIRHAVAQGHRTFVVSWRNPDASLAHKTWDDYIDEAVLTAIATVQQIAGAKQINALGFCVGGTMLATALAVLAAR
GEEPVASCTFLTTLIDFADTGILDVFIDEGFVRMRELQMGQGGLMKGQDLASTFSFLRPNDLVWNYVVGNYLKGETPPPF
DLLYWNSDSTNLPGPYYAWYLRNFYLENNLIRPGRLTVCGESLDLTQVQLPVYIYGSREDHIVPIGAAYASTQVLPGDKR
FVMGASGHIAGVINPPAKKKRSHWLREDGQLPATLDAWLAGATELPGSWWDDWCAWLHGHAGRQIAAPKAYGKAPKFKAI
EPAPGRYVQQKA

Sequences:

>Translated_572_residues
MSTNFDASWADSARQFQQMVGEGWSQMLQVLQPKEMGAALSMPAAGPVGFAPDKLAAVQQRYLQEVQALWSHALHHDDAP
LSNDRRFAGENWAHNPLSAFSVAAYQLQAHALMGLADAVQADDKTRARIRFSVEQWLAAMAPSNFLVFNADAQQKALETH
GESIAKGVANLLHDLGQGHISMTDESRFEVGRNVATTEGAVVFENELFQLLEYKPLTPKVYERPLLMVPPCINKYYILDL
QPDNSLIRHAVAQGHRTFVVSWRNPDASLAHKTWDDYIDEAVLTAIATVQQIAGAKQINALGFCVGGTMLATALAVLAAR
GEEPVASCTFLTTLIDFADTGILDVFIDEGFVRMRELQMGQGGLMKGQDLASTFSFLRPNDLVWNYVVGNYLKGETPPPF
DLLYWNSDSTNLPGPYYAWYLRNFYLENNLIRPGRLTVCGESLDLTQVQLPVYIYGSREDHIVPIGAAYASTQVLPGDKR
FVMGASGHIAGVINPPAKKKRSHWLREDGQLPATLDAWLAGATELPGSWWDDWCAWLHGHAGRQIAAPKAYGKAPKFKAI
EPAPGRYVQQKA
>Mature_571_residues
STNFDASWADSARQFQQMVGEGWSQMLQVLQPKEMGAALSMPAAGPVGFAPDKLAAVQQRYLQEVQALWSHALHHDDAPL
SNDRRFAGENWAHNPLSAFSVAAYQLQAHALMGLADAVQADDKTRARIRFSVEQWLAAMAPSNFLVFNADAQQKALETHG
ESIAKGVANLLHDLGQGHISMTDESRFEVGRNVATTEGAVVFENELFQLLEYKPLTPKVYERPLLMVPPCINKYYILDLQ
PDNSLIRHAVAQGHRTFVVSWRNPDASLAHKTWDDYIDEAVLTAIATVQQIAGAKQINALGFCVGGTMLATALAVLAARG
EEPVASCTFLTTLIDFADTGILDVFIDEGFVRMRELQMGQGGLMKGQDLASTFSFLRPNDLVWNYVVGNYLKGETPPPFD
LLYWNSDSTNLPGPYYAWYLRNFYLENNLIRPGRLTVCGESLDLTQVQLPVYIYGSREDHIVPIGAAYASTQVLPGDKRF
VMGASGHIAGVINPPAKKKRSHWLREDGQLPATLDAWLAGATELPGSWWDDWCAWLHGHAGRQIAAPKAYGKAPKFKAIE
PAPGRYVQQKA

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 63138; Mature: 63007

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNFDASWADSARQFQQMVGEGWSQMLQVLQPKEMGAALSMPAAGPVGFAPDKLAAVQQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEECCCCCCCCCCCCHHHHHHHH
RYLQEVQALWSHALHHDDAPLSNDRRFAGENWAHNPLSAFSVAAYQLQAHALMGLADAVQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADDKTRARIRFSVEQWLAAMAPSNFLVFNADAQQKALETHGESIAKGVANLLHDLGQGHI
CCCCCHHEEEECHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
SMTDESRFEVGRNVATTEGAVVFENELFQLLEYKPLTPKVYERPLLMVPPCINKYYILDL
EECCCHHHHHCCCEECCCCCEEEHHHHHHHHHCCCCCHHHHCCCEEECCCCCCCEEEEEE
QPDNSLIRHAVAQGHRTFVVSWRNPDASLAHKTWDDYIDEAVLTAIATVQQIAGAKQINA
CCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGFCVGGTMLATALAVLAARGEEPVASCTFLTTLIDFADTGILDVFIDEGFVRMRELQMG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCC
QGGLMKGQDLASTFSFLRPNDLVWNYVVGNYLKGETPPPFDLLYWNSDSTNLPGPYYAWY
CCCCCCCHHHHHHHHHCCCCCCEEHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHH
LRNFYLENNLIRPGRLTVCGESLDLTQVQLPVYIYGSREDHIVPIGAAYASTQVLPGDKR
HHHHHHCCCCCCCCCEEEECCCCCCEEEEEEEEEECCCCCCEEEEECHHHCCEECCCCCE
FVMGASGHIAGVINPPAKKKRSHWLREDGQLPATLDAWLAGATELPGSWWDDWCAWLHGH
EEEECCCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCC
AGRQIAAPKAYGKAPKFKAIEPAPGRYVQQKA
CCCEECCCHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STNFDASWADSARQFQQMVGEGWSQMLQVLQPKEMGAALSMPAAGPVGFAPDKLAAVQQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEECCCCCCCCCCCCHHHHHHHH
RYLQEVQALWSHALHHDDAPLSNDRRFAGENWAHNPLSAFSVAAYQLQAHALMGLADAVQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADDKTRARIRFSVEQWLAAMAPSNFLVFNADAQQKALETHGESIAKGVANLLHDLGQGHI
CCCCCHHEEEECHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
SMTDESRFEVGRNVATTEGAVVFENELFQLLEYKPLTPKVYERPLLMVPPCINKYYILDL
EECCCHHHHHCCCEECCCCCEEEHHHHHHHHHCCCCCHHHHCCCEEECCCCCCCEEEEEE
QPDNSLIRHAVAQGHRTFVVSWRNPDASLAHKTWDDYIDEAVLTAIATVQQIAGAKQINA
CCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGFCVGGTMLATALAVLAARGEEPVASCTFLTTLIDFADTGILDVFIDEGFVRMRELQMG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCC
QGGLMKGQDLASTFSFLRPNDLVWNYVVGNYLKGETPPPFDLLYWNSDSTNLPGPYYAWY
CCCCCCCHHHHHHHHHCCCCCCEEHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHH
LRNFYLENNLIRPGRLTVCGESLDLTQVQLPVYIYGSREDHIVPIGAAYASTQVLPGDKR
HHHHHHCCCCCCCCCEEEECCCCCCEEEEEEEEEECCCCCCEEEEECHHHCCEECCCCCE
FVMGASGHIAGVINPPAKKKRSHWLREDGQLPATLDAWLAGATELPGSWWDDWCAWLHGH
EEEECCCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCC
AGRQIAAPKAYGKAPKFKAIEPAPGRYVQQKA
CCCEECCCHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670936; 1987116 [H]