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The map label for this gene is dnaQ [H]

Identifier: 222110838

GI number: 222110838

Start: 1735218

End: 1735931

Strand: Direct

Name: dnaQ [H]

Synonym: Dtpsy_1644

Alternate gene names: 222110838

Gene position: 1735218-1735931 (Clockwise)

Preceding gene: 222110837

Following gene: 222110839

Centisome position: 45.7

GC content: 62.89

Gene sequence:

>714_bases
ATGTCCCGACAGATTGTTCTGGACACGGAGACCACCGGCCTGTCGGCGGAAGGGGGCGACCGCATCATCGAGCTGGGCTG
CGTGGAGCTCGTCAACCGCAAGCTCACCGGCAACAATCTGCATCTGTACCTGAACCCCGAGCGCGACAGCCATGAGGACG
CGCTGAAGGTGCACGGCATCAGCAATGAATTCCTGCGCGACAAGCCCAAGTTTGCCGAGCGGGTGCAAGACATCCTGCAA
TACCTGCAGGGCGCGGAACTCATCATCCACAACGCGAGCTTCGACGTGGGCTTCCTGGACAAGGAGCTGGAACTGGTCGG
CCTGGCGCCGCTGTCCGCGCATGTCGGGGGCGTGATCGACACCCTGGCCATGGCCAAGGAGATGTTCCCGGGCAAGCGCA
ACTCGCTGGACTCGCTGTGCGACCGGCTGGGCGTTGACAATTCCAGTCGTACGCTGCACGGCGCCTTGCTGGACGCGGAG
TTGCTGGCGGATGTCTACATCAACATGACCCGCGGGCAGGATGCCCTGCTGATCATGGATGAGGCCACCGCCGGGGCAGG
AGGCACCACCGTGGCCGCGGTAGATCTGAGCCGCATTGCGCTGACGGTGCTGACCGCCAGTGCGCAGGAGCTTGCCGAGC
ATGAGGAAGTACTCGTGCAGATCGACAAGTCCAGCGGCGGTAAAACAATTTGGCGGACTTTGTCTGAGGCGTGA

Upstream 100 bases:

>100_bases
AGCCGCAATCGCGCCTGTCGTGCCAGGCCATCCTGGCGCAGAGCGATGTGACGGTGGAGATTCCCAAGTACTCGATCAAC
CACGCCAAGGAGAACCACTG

Downstream 100 bases:

>100_bases
GAAAGCTATGCCATAATCGCGGGCTGTCGCAGCAACGACACGGGTGATTAGCTCAGCGGTAGAGCACTGCCTTCACACGG
CAGGGGTCACATGTTCGATC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSRQIVLDTETTGLSAEGGDRIIELGCVELVNRKLTGNNLHLYLNPERDSHEDALKVHGISNEFLRDKPKFAERVQDILQ
YLQGAELIIHNASFDVGFLDKELELVGLAPLSAHVGGVIDTLAMAKEMFPGKRNSLDSLCDRLGVDNSSRTLHGALLDAE
LLADVYINMTRGQDALLIMDEATAGAGGTTVAAVDLSRIALTVLTASAQELAEHEEVLVQIDKSSGGKTIWRTLSEA

Sequences:

>Translated_237_residues
MSRQIVLDTETTGLSAEGGDRIIELGCVELVNRKLTGNNLHLYLNPERDSHEDALKVHGISNEFLRDKPKFAERVQDILQ
YLQGAELIIHNASFDVGFLDKELELVGLAPLSAHVGGVIDTLAMAKEMFPGKRNSLDSLCDRLGVDNSSRTLHGALLDAE
LLADVYINMTRGQDALLIMDEATAGAGGTTVAAVDLSRIALTVLTASAQELAEHEEVLVQIDKSSGGKTIWRTLSEA
>Mature_236_residues
SRQIVLDTETTGLSAEGGDRIIELGCVELVNRKLTGNNLHLYLNPERDSHEDALKVHGISNEFLRDKPKFAERVQDILQY
LQGAELIIHNASFDVGFLDKELELVGLAPLSAHVGGVIDTLAMAKEMFPGKRNSLDSLCDRLGVDNSSRTLHGALLDAEL
LADVYINMTRGQDALLIMDEATAGAGGTTVAAVDLSRIALTVLTASAQELAEHEEVLVQIDKSSGGKTIWRTLSEA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=239, Percent_Identity=49.7907949790795, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25632; Mature: 25501

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQIVLDTETTGLSAEGGDRIIELGCVELVNRKLTGNNLHLYLNPERDSHEDALKVHGI
CCCEEEEECCCCCCCCCCCCEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECC
SNEFLRDKPKFAERVQDILQYLQGAELIIHNASFDVGFLDKELELVGLAPLSAHVGGVID
CHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHH
TLAMAKEMFPGKRNSLDSLCDRLGVDNSSRTLHGALLDAELLADVYINMTRGQDALLIMD
HHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEE
EATAGAGGTTVAAVDLSRIALTVLTASAQELAEHEEVLVQIDKSSGGKTIWRTLSEA
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
SRQIVLDTETTGLSAEGGDRIIELGCVELVNRKLTGNNLHLYLNPERDSHEDALKVHGI
CCEEEEECCCCCCCCCCCCEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECC
SNEFLRDKPKFAERVQDILQYLQGAELIIHNASFDVGFLDKELELVGLAPLSAHVGGVID
CHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHH
TLAMAKEMFPGKRNSLDSLCDRLGVDNSSRTLHGALLDAELLADVYINMTRGQDALLIMD
HHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEE
EATAGAGGTTVAAVDLSRIALTVLTASAQELAEHEEVLVQIDKSSGGKTIWRTLSEA
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]