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The map label for this gene is ribB [H]

Identifier: 222110808

GI number: 222110808

Start: 1704042

End: 1704713

Strand: Direct

Name: ribB [H]

Synonym: Dtpsy_1613

Alternate gene names: 222110808

Gene position: 1704042-1704713 (Clockwise)

Preceding gene: 222110807

Following gene: 222110811

Centisome position: 44.88

GC content: 70.68

Gene sequence:

>672_bases
ATGTCTTTTCCCGCCACTTTCTTGTCCGCCCCTGGCGATCTCCCACAGGAGGTCACGCTCGCGCCCATGCCAGCGGTGAT
CGCTGCGATCGCGGCCGGCCGCCCTGTACTGGTGCTCGATGACGCCGACCGCGAAAACGAGGCCGATCTGGTCTGCGCTG
CCGCCAACATGACCGAGGCCACCATGGCACTCATGATCCGTGAGGGCAGCGGCATCGTTTGCCTGTGCCTGACGCCCGCG
CATGCCAAGGCGCTGGGGTTGCGGCCCATGGTGGAGGTGAACCGCTCGGCGTTCTCCACCGCGTTCACCCAGTCCATCGA
AGCCGCGCATGGCGTGAGTACCGGCGTGTCGGCGGCCGACCGTCTGCAGACCGTGCGGTGCGCCCTGCGCATTCCGGCGC
CGGGGTGCGTGCCCGAGGTCGTAAGCCCGGGCCACGTGTTCCCACTGGTGGCACGCGCGGGCGGGGTGCTGGAGCGTGAC
GGCCATACCGAGTCGGCCGTGGACCTGGCCGTGCTGGCCGGCCTGCCGCCTGCGGGCGTGCTGTGCGAGCTCATGAACCC
CGACGGCAGCATGGCGCGCGGCGCACAGGTGGCCCGCTTTGCCCGTGCGCATGGCTTGCTGTGCACCACGGTGCGGGCGC
TGGCCGACTACCGTCGCGCGCGCCAGCCCTGA

Upstream 100 bases:

>100_bases
GGCCGTGTGCTTCGCGCGTGCCGGGCCCCGGGCCCATGGCGCGCGTGGGTGCTTCTTGCATGCCTTGAGGCGTTTCTTCA
TTTCAACCGAGGAGCGTTTC

Downstream 100 bases:

>100_bases
CACCGCGCTAGACCCAGCCGAACGCGCCCAGCAACGCCCCCGCGCCCAGCAGCCATAACAGGTGGATGCGCGTGCGCCAC
ACCAGCAGGGTGGTGGCCGC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSFPATFLSAPGDLPQEVTLAPMPAVIAAIAAGRPVLVLDDADRENEADLVCAAANMTEATMALMIREGSGIVCLCLTPA
HAKALGLRPMVEVNRSAFSTAFTQSIEAAHGVSTGVSAADRLQTVRCALRIPAPGCVPEVVSPGHVFPLVARAGGVLERD
GHTESAVDLAVLAGLPPAGVLCELMNPDGSMARGAQVARFARAHGLLCTTVRALADYRRARQP

Sequences:

>Translated_223_residues
MSFPATFLSAPGDLPQEVTLAPMPAVIAAIAAGRPVLVLDDADRENEADLVCAAANMTEATMALMIREGSGIVCLCLTPA
HAKALGLRPMVEVNRSAFSTAFTQSIEAAHGVSTGVSAADRLQTVRCALRIPAPGCVPEVVSPGHVFPLVARAGGVLERD
GHTESAVDLAVLAGLPPAGVLCELMNPDGSMARGAQVARFARAHGLLCTTVRALADYRRARQP
>Mature_222_residues
SFPATFLSAPGDLPQEVTLAPMPAVIAAIAAGRPVLVLDDADRENEADLVCAAANMTEATMALMIREGSGIVCLCLTPAH
AKALGLRPMVEVNRSAFSTAFTQSIEAAHGVSTGVSAADRLQTVRCALRIPAPGCVPEVVSPGHVFPLVARAGGVLERDG
HTESAVDLAVLAGLPPAGVLCELMNPDGSMARGAQVARFARAHGLLCTTVRALADYRRARQP

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=197, Percent_Identity=55.8375634517767, Blast_Score=207, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6320695, Length=210, Percent_Identity=38.0952380952381, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23071; Mature: 22940

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPATFLSAPGDLPQEVTLAPMPAVIAAIAAGRPVLVLDDADRENEADLVCAAANMTEA
CCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHH
TMALMIREGSGIVCLCLTPAHAKALGLRPMVEVNRSAFSTAFTQSIEAAHGVSTGVSAAD
EEEEEEECCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RLQTVRCALRIPAPGCVPEVVSPGHVFPLVARAGGVLERDGHTESAVDLAVLAGLPPAGV
HHHHHHHEEECCCCCCCHHHCCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCHHH
LCELMNPDGSMARGAQVARFARAHGLLCTTVRALADYRRARQP
EEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFPATFLSAPGDLPQEVTLAPMPAVIAAIAAGRPVLVLDDADRENEADLVCAAANMTEA
CCCCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCHHH
TMALMIREGSGIVCLCLTPAHAKALGLRPMVEVNRSAFSTAFTQSIEAAHGVSTGVSAAD
EEEEEEECCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RLQTVRCALRIPAPGCVPEVVSPGHVFPLVARAGGVLERDGHTESAVDLAVLAGLPPAGV
HHHHHHHEEECCCCCCCHHHCCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCHHH
LCELMNPDGSMARGAQVARFARAHGLLCTTVRALADYRRARQP
EEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]