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The map label for this gene is ltrA [H]

Identifier: 222110715

GI number: 222110715

Start: 1599956

End: 1600909

Strand: Direct

Name: ltrA [H]

Synonym: Dtpsy_1518

Alternate gene names: 222110715

Gene position: 1599956-1600909 (Clockwise)

Preceding gene: 222110713

Following gene: 222110716

Centisome position: 42.14

GC content: 71.38

Gene sequence:

>954_bases
ATGCAGGATCTGAACGACATGCTTTATTTCGCCGAGGTGGCCGAGCGCGGCGGCTTTGCCGCGGCGGGCCGGGCGCTGGG
GATCCCGAAGTCGCGCCTGTCGCGCCGCGTGGCCGAGTTGGAAGCGCGCCTGGGCGTGCGCCTGCTGCAGCGCACCACGC
GCACGCTGTCGCTCACCGAGGTGGGCGAGGCCTACCTGCGCCATTGCCAGGCCATGCGTGATTCGGCCCAGGCAGCGCAG
GACACGGTGGACCAGGTACAGACCGAACCGCGCGGCACCGTGCGCGTGACCTGCCCGGTGACGCTGGCGCAGACGGTGGT
GGCCGAGCTGATGCCGCAGTTCCTGCAGCGCCACCCCCAGGTGCGCCTGGAGATGCAGGTCACCAACCGCGTGGTGAACG
TGGTGGAAGAGGGCGTGGACGTGGCGCTGCGCGTGCGCCCCACGCTGGAGGACAGCGGCAGCATGGTGGTCAAGCGCCTG
GACGAGGTGCGCCTGCTGCTGGTGGCCAGCCCCGAGCAACTGCGGCGCCAGGGCACGCCCACCTCGCTGCGCGACCTGGC
GCTGCTGGACACGCTGGCCATGTCCGCGGCCGACGGGCGCGCCAGCCTGCGCCTGATCGGCCCCGAGGGGCGCGAGGAAA
CCGTGCACTTCACGCCGCGCTACGTGGCCGACGACCTGCTGACGCTCAAATTCGCCGCGTTGGCGGGCACGGGCCTGTGC
TGGATGCCGGACTACATGTGCATGTCCGAATTGCAGGAGGGCCGGCTGGTGCACCTGCTGCCCCAGTGGACGCAGCCGCG
CAGCGTGGTGCATGCAGTGTTTGCGTCGCGTCGCGGCTTGTCGCCGGCGGTGCGCAGCTTCCTGGACTTTCTGGGTGAAA
CCGTGCCCGGCCATTCCGCCGCGGTCTGTGAGCGGGGCGACACGGCCACGGCCGGCGCGGCACTGCCCCGCTGA

Upstream 100 bases:

>100_bases
CCGCAATGGGGCGATGGATAGATTGTCGTTTTGGACCGAATGTTTGATAAGCAGGCGGTGATGCGATAGATTGTTCTGAA
TTTGGAACGAAAGGCGAGCG

Downstream 100 bases:

>100_bases
TGCGGCGGCGCGTGGTGTACGCAAGAGCGCGGGATGCATGGGCGGTGCGGCTTGATCCCCAGTGGGGGGGCGATGTAAGG
GTGCTTTGCTTTTGATAGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MQDLNDMLYFAEVAERGGFAAAGRALGIPKSRLSRRVAELEARLGVRLLQRTTRTLSLTEVGEAYLRHCQAMRDSAQAAQ
DTVDQVQTEPRGTVRVTCPVTLAQTVVAELMPQFLQRHPQVRLEMQVTNRVVNVVEEGVDVALRVRPTLEDSGSMVVKRL
DEVRLLLVASPEQLRRQGTPTSLRDLALLDTLAMSAADGRASLRLIGPEGREETVHFTPRYVADDLLTLKFAALAGTGLC
WMPDYMCMSELQEGRLVHLLPQWTQPRSVVHAVFASRRGLSPAVRSFLDFLGETVPGHSAAVCERGDTATAGAALPR

Sequences:

>Translated_317_residues
MQDLNDMLYFAEVAERGGFAAAGRALGIPKSRLSRRVAELEARLGVRLLQRTTRTLSLTEVGEAYLRHCQAMRDSAQAAQ
DTVDQVQTEPRGTVRVTCPVTLAQTVVAELMPQFLQRHPQVRLEMQVTNRVVNVVEEGVDVALRVRPTLEDSGSMVVKRL
DEVRLLLVASPEQLRRQGTPTSLRDLALLDTLAMSAADGRASLRLIGPEGREETVHFTPRYVADDLLTLKFAALAGTGLC
WMPDYMCMSELQEGRLVHLLPQWTQPRSVVHAVFASRRGLSPAVRSFLDFLGETVPGHSAAVCERGDTATAGAALPR
>Mature_317_residues
MQDLNDMLYFAEVAERGGFAAAGRALGIPKSRLSRRVAELEARLGVRLLQRTTRTLSLTEVGEAYLRHCQAMRDSAQAAQ
DTVDQVQTEPRGTVRVTCPVTLAQTVVAELMPQFLQRHPQVRLEMQVTNRVVNVVEEGVDVALRVRPTLEDSGSMVVKRL
DEVRLLLVASPEQLRRQGTPTSLRDLALLDTLAMSAADGRASLRLIGPEGREETVHFTPRYVADDLLTLKFAALAGTGLC
WMPDYMCMSELQEGRLVHLLPQWTQPRSVVHAVFASRRGLSPAVRSFLDFLGETVPGHSAAVCERGDTATAGAALPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=33.1081081081081, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789639, Length=291, Percent_Identity=30.9278350515464, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI87081978, Length=309, Percent_Identity=29.7734627831715, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=26.551724137931, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=27.9863481228669, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=29.0969899665552, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=23.9583333333333, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI157672245, Length=118, Percent_Identity=32.2033898305085, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=27.34375, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082132, Length=300, Percent_Identity=24.3333333333333, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790208, Length=171, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790011, Length=264, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=183, Percent_Identity=26.2295081967213, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34849; Mature: 34849

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLNDMLYFAEVAERGGFAAAGRALGIPKSRLSRRVAELEARLGVRLLQRTTRTLSLTE
CCCHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEAYLRHCQAMRDSAQAAQDTVDQVQTEPRGTVRVTCPVTLAQTVVAELMPQFLQRHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCC
VRLEMQVTNRVVNVVEEGVDVALRVRPTLEDSGSMVVKRLDEVRLLLVASPEQLRRQGTP
EEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEECHHHHHHCCCC
TSLRDLALLDTLAMSAADGRASLRLIGPEGREETVHFTPRYVADDLLTLKFAALAGTGLC
CHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCC
WMPDYMCMSELQEGRLVHLLPQWTQPRSVVHAVFASRRGLSPAVRSFLDFLGETVPGHSA
CCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCH
AVCERGDTATAGAALPR
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQDLNDMLYFAEVAERGGFAAAGRALGIPKSRLSRRVAELEARLGVRLLQRTTRTLSLTE
CCCHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEAYLRHCQAMRDSAQAAQDTVDQVQTEPRGTVRVTCPVTLAQTVVAELMPQFLQRHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCC
VRLEMQVTNRVVNVVEEGVDVALRVRPTLEDSGSMVVKRLDEVRLLLVASPEQLRRQGTP
EEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEECHHHHHHCCCC
TSLRDLALLDTLAMSAADGRASLRLIGPEGREETVHFTPRYVADDLLTLKFAALAGTGLC
CHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCC
WMPDYMCMSELQEGRLVHLLPQWTQPRSVVHAVFASRRGLSPAVRSFLDFLGETVPGHSA
CCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCH
AVCERGDTATAGAALPR
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]