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The map label for this gene is intZ [H]

Identifier: 222110465

GI number: 222110465

Start: 1325211

End: 1326467

Strand: Direct

Name: intZ [H]

Synonym: Dtpsy_1262

Alternate gene names: 222110465

Gene position: 1325211-1326467 (Clockwise)

Preceding gene: 222110464

Following gene: 222110466

Centisome position: 34.91

GC content: 63.72

Gene sequence:

>1257_bases
ATGCTTACCGACACCGCACTGCGCAATTTCAAGCCTAAGTCCAAGACTTACAAGGCTTCCGACCGTGACGGCATGTACGT
GACGGTATCGCCCACCGGTACCGTCACTTTCCGCTTCGATTACCGTCTCAACGGCCGGCGCGAGACGCTGACCATTGGAC
GGTATGGGCCGTCCGGCATTTCGCTCGCGATGGCCCGCGAAAAGCTGCTGGATGCCAAGAAGGCTGTCGCCCTGGGCAAA
TCCCCCGCGCTGGAGAAGCAGCGCGAGAAACGCCGACTGACCTCCGCCAAGAACTTCGGCGACATGACCTCCCAATGGCT
GGCCGGTGCCCGGATGGCCGACAGCACGCGAGCGATGCGCAAGAGCATCGTCGATCGGGACATCCTGCCGGCCTTCCAGA
ACCGCCTGCTCAACGAAGTCACCGCCGACGACTTGCGCGCCTTGTGCGGCAAGGTGAAGGGGCGCGGCGCCCCGGCCACC
GCGGTGCACATTCGCGACATCGTGAAGCAGGTCTATGCCTTCGCCATCCTGCATGGGGAGAAGGTAGACAACCCGGCGGC
CGACGTGGGCGCAGCCTCGATTGCGACCTTCGTGCCCAAGGACCGCGCCTTGTCGCCGCTGGAGATCCGCTTGATGTCGC
GGCAGATGGAGTCGGTGGCCACCTATCCGACCATTCGGCTGGCGTTGCGAATGATCCTGCTGACGCTGGTGCGCAAGAGC
GAGCTGATCGAGGCCACCTGGGACGAGGTCGATTTCGAGAACGCGACCTGGACCATTCCGAAGCAGCGGATGAAGGGGCG
CAACCCACATGTGATCTACCTGTCGCGCCAGGCGTTGGACATCCTCGTGGCGCTGCACACCTGCGCGGCCGGCTCGAAGT
TCGTGCTGCCATCGCGCTACGACTCCGACCATTGCATGTCTCACGCGACTCTCAACCGGGTCACGCAGATCGTGGCGCAA
CGGGCCAAGGCCGCAGGCCTGCCGCTGGAGCCGTTCACCGTCCACGATCTGCGCCGCACAGGTTCGACGTTGCTCAACGA
GATCGGGTTCAACCGAGACTGGATCGAGAAGTGCCTTGCGCACGAAGAAGGGCGTTCCTCGCGCTCGATCTACAACAAGG
CCGAGTACGCCGAGCAGCGGCGCCACATGCTGCAGGAGTGGGCCAACATGGTCGATGCCTGGATCGACGGGCAGACCTAC
GTGCCGAAGCTGATGCCGGAGAACGTGGTCGTGCCGGTGTTGAGTGCGATGGCCTGA

Upstream 100 bases:

>100_bases
TCACTCCTCTGGAAAGCTTGTTTTATGCGGCTTTCCGGGCATCAGCAGGTCTCCTGACCCCTGACGGTAAAAGCCGTCAT
GAACAGGAGGAAAAACCTCG

Downstream 100 bases:

>100_bases
AGCATGGCCGAGGTTGTCGCTTGACAACCTCGGCAATCATTCCCATACTGGAGACTGTTGATGGCCCGGCCCTCTCATCC
GAAGAAAGAAGTCGAGGAAG

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLTDTALRNFKPKSKTYKASDRDGMYVTVSPTGTVTFRFDYRLNGRRETLTIGRYGPSGISLAMAREKLLDAKKAVALGK
SPALEKQREKRRLTSAKNFGDMTSQWLAGARMADSTRAMRKSIVDRDILPAFQNRLLNEVTADDLRALCGKVKGRGAPAT
AVHIRDIVKQVYAFAILHGEKVDNPAADVGAASIATFVPKDRALSPLEIRLMSRQMESVATYPTIRLALRMILLTLVRKS
ELIEATWDEVDFENATWTIPKQRMKGRNPHVIYLSRQALDILVALHTCAAGSKFVLPSRYDSDHCMSHATLNRVTQIVAQ
RAKAAGLPLEPFTVHDLRRTGSTLLNEIGFNRDWIEKCLAHEEGRSSRSIYNKAEYAEQRRHMLQEWANMVDAWIDGQTY
VPKLMPENVVVPVLSAMA

Sequences:

>Translated_418_residues
MLTDTALRNFKPKSKTYKASDRDGMYVTVSPTGTVTFRFDYRLNGRRETLTIGRYGPSGISLAMAREKLLDAKKAVALGK
SPALEKQREKRRLTSAKNFGDMTSQWLAGARMADSTRAMRKSIVDRDILPAFQNRLLNEVTADDLRALCGKVKGRGAPAT
AVHIRDIVKQVYAFAILHGEKVDNPAADVGAASIATFVPKDRALSPLEIRLMSRQMESVATYPTIRLALRMILLTLVRKS
ELIEATWDEVDFENATWTIPKQRMKGRNPHVIYLSRQALDILVALHTCAAGSKFVLPSRYDSDHCMSHATLNRVTQIVAQ
RAKAAGLPLEPFTVHDLRRTGSTLLNEIGFNRDWIEKCLAHEEGRSSRSIYNKAEYAEQRRHMLQEWANMVDAWIDGQTY
VPKLMPENVVVPVLSAMA
>Mature_418_residues
MLTDTALRNFKPKSKTYKASDRDGMYVTVSPTGTVTFRFDYRLNGRRETLTIGRYGPSGISLAMAREKLLDAKKAVALGK
SPALEKQREKRRLTSAKNFGDMTSQWLAGARMADSTRAMRKSIVDRDILPAFQNRLLNEVTADDLRALCGKVKGRGAPAT
AVHIRDIVKQVYAFAILHGEKVDNPAADVGAASIATFVPKDRALSPLEIRLMSRQMESVATYPTIRLALRMILLTLVRKS
ELIEATWDEVDFENATWTIPKQRMKGRNPHVIYLSRQALDILVALHTCAAGSKFVLPSRYDSDHCMSHATLNRVTQIVAQ
RAKAAGLPLEPFTVHDLRRTGSTLLNEIGFNRDWIEKCLAHEEGRSSRSIYNKAEYAEQRRHMLQEWANMVDAWIDGQTY
VPKLMPENVVVPVLSAMA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=404, Percent_Identity=32.1782178217822, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1788974, Length=399, Percent_Identity=30.0751879699248, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788690, Length=396, Percent_Identity=28.030303030303, Blast_Score=154, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46886; Mature: 46886

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDTALRNFKPKSKTYKASDRDGMYVTVSPTGTVTFRFDYRLNGRRETLTIGRYGPSGI
CCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCEEEEEEECCCCCCH
SLAMAREKLLDAKKAVALGKSPALEKQREKRRLTSAKNFGDMTSQWLAGARMADSTRAMR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
KSIVDRDILPAFQNRLLNEVTADDLRALCGKVKGRGAPATAVHIRDIVKQVYAFAILHGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KVDNPAADVGAASIATFVPKDRALSPLEIRLMSRQMESVATYPTIRLALRMILLTLVRKS
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ELIEATWDEVDFENATWTIPKQRMKGRNPHVIYLSRQALDILVALHTCAAGSKFVLPSRY
HHHHHHHHHCCCCCCEEECCHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEECCCCC
DSDHCMSHATLNRVTQIVAQRAKAAGLPLEPFTVHDLRRTGSTLLNEIGFNRDWIEKCLA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
HEEGRSSRSIYNKAEYAEQRRHMLQEWANMVDAWIDGQTYVPKLMPENVVVPVLSAMA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLTDTALRNFKPKSKTYKASDRDGMYVTVSPTGTVTFRFDYRLNGRRETLTIGRYGPSGI
CCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCEEEEEEECCCCCCH
SLAMAREKLLDAKKAVALGKSPALEKQREKRRLTSAKNFGDMTSQWLAGARMADSTRAMR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
KSIVDRDILPAFQNRLLNEVTADDLRALCGKVKGRGAPATAVHIRDIVKQVYAFAILHGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KVDNPAADVGAASIATFVPKDRALSPLEIRLMSRQMESVATYPTIRLALRMILLTLVRKS
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ELIEATWDEVDFENATWTIPKQRMKGRNPHVIYLSRQALDILVALHTCAAGSKFVLPSRY
HHHHHHHHHCCCCCCEEECCHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEECCCCC
DSDHCMSHATLNRVTQIVAQRAKAAGLPLEPFTVHDLRRTGSTLLNEIGFNRDWIEKCLA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
HEEGRSSRSIYNKAEYAEQRRHMLQEWANMVDAWIDGQTYVPKLMPENVVVPVLSAMA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]