Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 222110443

GI number: 222110443

Start: 1301789

End: 1304083

Strand: Direct

Name: rnr [H]

Synonym: Dtpsy_1240

Alternate gene names: 222110443

Gene position: 1301789-1304083 (Clockwise)

Preceding gene: 222110441

Following gene: 222110444

Centisome position: 34.29

GC content: 63.14

Gene sequence:

>2295_bases
TTGTATATCAAAAAAAATCACTCTGAATCATCCGTCGCCAAAGTTTCACTGGACGAGATCGAAGGCACCGTCCAGGGACA
CCGCGACGGGCATGGCTTCGTCCTGCGCGATGACGGCCAGCCTGACATTTACCTTCCTGCCAATGAGATGCGGGCGGTAT
TGCACAAGGACCGGGTGCGCGTGCGCATCGCGCGCCAGGACCGGCGCGGCCGGCCTGAAGGCCGCGTGGTCGAGATTCTG
GAGCGCCCGCCCCAACCCATCATCGGGCGCCTTCTTCAGGAGAGCGGTGTCTGGCTGGTCGCCCCTGAGGACAAACGGTA
CGGCCAGGACGTGCTGATTCCCAAGGGTGCTACGGGGGCTGCTGCGACGGGACAGGTCGTGGTGGTGGAACTGACCGAGC
CGCCGGCTTTGTTTGGGCAACCCGTGGGGCGGGTGGTCGAAGTGCTGGGGGAGGTAGATGACCCCGGGATGGAGGTGGAA
ATTGCCGTGCGCAAATACGGGGTTCCGCACGAATTCTCCGAAGCGTGCCTTGACCAGGCGAAGGCGCTGCCGGACAAGGT
GCGCGCTCAGGACAAGCGTCGACGCGTTGATCTGACGGATGTCCCCCTGGTCACCATCGATGGTGAAGATGCGCGCGACT
TCGACGACGCGGTGTATTGCGAGCCCGCCAAGATCGGGCGCGCCAAGGGGTGGCGCCTGCTCGTGGCCATCGCGGACGTG
AGCCACTATGTGGAGACGGGCAATGCCATCGATATTGACGCCTACGACCGGGCGACCAGCGTTTATTTCCCGCGGCGCGT
TATCCCCATGCTGCCGGAGAAGCTCTCCAACGGGCTGTGCTCGCTGAACCCCCATGTCGAGCGCCTGTGCATGGTGTGCG
ACATGATGGTTACCGCCAAAGGTGAAATTCACGCCTATCAGTTCTATCCTGCGGTCATGCTCAGCCACGCGCGGCTTACC
TATACCGAGGTGGCTGCGGTGCTGGCCAATACGCGCGGCCCGGAAGCGCTGAAGCATCAAGAGCGCGTGGGCAACCTGCT
CAACCTCTACGAGGTCTACCGCGCATTGCTAGCCGCGCGGCAGGCGCGCGGCGCCGTGGACTTCGAGACGACCGAGACGC
AAATCGTCTGTGATGACAATGGCCGTATCGAGAAAATCGTCCCCCGTGTACGCACCGAGGCGCACCGCCTGATTGAGGAG
GCGATGCTCGCCGCCAACGTCTGCAGCGCCGATTTCATCGGTCATGCCGGCCGGGCGGGGCTGTATCGCGTTCATGAGGG
GCCTACGCCGGAGAAGCAAGAGATCCTGCGTGCATATCTCAAAGCCATGGGTGTTGGCATGTCGATCGGGGACGATCCGC
GGCCGGCAGAATTCCAGGCGATTGCCGAGGCCACCAAGGACCGGGTGGATGCGCAGCAGATCCACACCATGCTGCTGCGT
TCGATGCAGCAGGCGATCTACACGCCTGTCAACAGCGGTCACTTCGGTTTGGCATTCGAAGCCTATACACACTTCACCAG
TCCTATTCGCCGCTACCCGGATCTGCTGGTGCATCGCGTGATCAAGTCCATCTTGAGCGGCACCAAATATGTGCTGCCCG
CGCTGCCGACGCCGGGGGAGGCTCAGTTCAAGCTGGCCAAGCGTCTGGCTTCCAAGGGCGGAGAATCCTCTGCACGCCCT
TCCAAGACGGGTGGCGTTATCAGCGTCCGGGAGACGCAGGCGTGGGAGGCCGCGGGACTGCACTGCAGTGCGAACGAACG
CCGTGCGGACGAGGCCAGTCGTGACGTGGAAGCATGGCTCAAGTGCCAGTACATGCGTGAGCATCTGGGTGAGGAGTACA
GCGGTGTCGTCAGCGCGGTGACGAGCTTCGGCATCTTCGTGACGCTTGATGCCCTCTATGTGGAAGGGCTGGTGCACATC
ACGGAACTGGGTGGGGAGTACTTTAAGTTCGATGAGGCGCGGCAAGAACTGCGGGGGGAGCGCACGGGTATCCGCTATGC
GATTGGTGCACGCGTGCGTGTTCAGGTCAGCCGCGTCGACCTCGATGGCCGCAAGATCGACTTCCGGCTGGTGCATGAAG
CCGGCGATGGTTTCTCCACCAAAGGCCCCAAGTCCAGGGACGGCGCGAAACGCGGGTCCTCGGCAGCGGCCTTGGATGGT
CGATCCGCCTCGGTGCCCACGGCCCGGGAAAGCAGAGAGGAGGGGAGCCGGCGGCGCCCGCACAAGCAGGCCTTGGCCGG
CAAAAAAGCGGCAGGTGGCAAGAACCCCTCTAAGGGCCGCAAATCCCGCGGTTGA

Upstream 100 bases:

>100_bases
GCCCAGGAGAGGACTCGAACCTCCACGATGTTACTCGCTAGTACCTGAAACTAGTGCGTCTACCAATTCCGCCACCTGGG
CATTTCAGGAAAGTCATAGA

Downstream 100 bases:

>100_bases
GTAGATTGATGGGTATGAAGGACAGGAGACAAGCGTCGCATATGGTTAAAGCATCGAAGGTGGCCATCGTTACTGGGGCT
GGGTCAGGGATTGGCAAGGC

Product: ribonuclease r

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MYIKKNHSESSVAKVSLDEIEGTVQGHRDGHGFVLRDDGQPDIYLPANEMRAVLHKDRVRVRIARQDRRGRPEGRVVEIL
ERPPQPIIGRLLQESGVWLVAPEDKRYGQDVLIPKGATGAAATGQVVVVELTEPPALFGQPVGRVVEVLGEVDDPGMEVE
IAVRKYGVPHEFSEACLDQAKALPDKVRAQDKRRRVDLTDVPLVTIDGEDARDFDDAVYCEPAKIGRAKGWRLLVAIADV
SHYVETGNAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPHVERLCMVCDMMVTAKGEIHAYQFYPAVMLSHARLT
YTEVAAVLANTRGPEALKHQERVGNLLNLYEVYRALLAARQARGAVDFETTETQIVCDDNGRIEKIVPRVRTEAHRLIEE
AMLAANVCSADFIGHAGRAGLYRVHEGPTPEKQEILRAYLKAMGVGMSIGDDPRPAEFQAIAEATKDRVDAQQIHTMLLR
SMQQAIYTPVNSGHFGLAFEAYTHFTSPIRRYPDLLVHRVIKSILSGTKYVLPALPTPGEAQFKLAKRLASKGGESSARP
SKTGGVISVRETQAWEAAGLHCSANERRADEASRDVEAWLKCQYMREHLGEEYSGVVSAVTSFGIFVTLDALYVEGLVHI
TELGGEYFKFDEARQELRGERTGIRYAIGARVRVQVSRVDLDGRKIDFRLVHEAGDGFSTKGPKSRDGAKRGSSAAALDG
RSASVPTARESREEGSRRRPHKQALAGKKAAGGKNPSKGRKSRG

Sequences:

>Translated_764_residues
MYIKKNHSESSVAKVSLDEIEGTVQGHRDGHGFVLRDDGQPDIYLPANEMRAVLHKDRVRVRIARQDRRGRPEGRVVEIL
ERPPQPIIGRLLQESGVWLVAPEDKRYGQDVLIPKGATGAAATGQVVVVELTEPPALFGQPVGRVVEVLGEVDDPGMEVE
IAVRKYGVPHEFSEACLDQAKALPDKVRAQDKRRRVDLTDVPLVTIDGEDARDFDDAVYCEPAKIGRAKGWRLLVAIADV
SHYVETGNAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPHVERLCMVCDMMVTAKGEIHAYQFYPAVMLSHARLT
YTEVAAVLANTRGPEALKHQERVGNLLNLYEVYRALLAARQARGAVDFETTETQIVCDDNGRIEKIVPRVRTEAHRLIEE
AMLAANVCSADFIGHAGRAGLYRVHEGPTPEKQEILRAYLKAMGVGMSIGDDPRPAEFQAIAEATKDRVDAQQIHTMLLR
SMQQAIYTPVNSGHFGLAFEAYTHFTSPIRRYPDLLVHRVIKSILSGTKYVLPALPTPGEAQFKLAKRLASKGGESSARP
SKTGGVISVRETQAWEAAGLHCSANERRADEASRDVEAWLKCQYMREHLGEEYSGVVSAVTSFGIFVTLDALYVEGLVHI
TELGGEYFKFDEARQELRGERTGIRYAIGARVRVQVSRVDLDGRKIDFRLVHEAGDGFSTKGPKSRDGAKRGSSAAALDG
RSASVPTARESREEGSRRRPHKQALAGKKAAGGKNPSKGRKSRG
>Mature_764_residues
MYIKKNHSESSVAKVSLDEIEGTVQGHRDGHGFVLRDDGQPDIYLPANEMRAVLHKDRVRVRIARQDRRGRPEGRVVEIL
ERPPQPIIGRLLQESGVWLVAPEDKRYGQDVLIPKGATGAAATGQVVVVELTEPPALFGQPVGRVVEVLGEVDDPGMEVE
IAVRKYGVPHEFSEACLDQAKALPDKVRAQDKRRRVDLTDVPLVTIDGEDARDFDDAVYCEPAKIGRAKGWRLLVAIADV
SHYVETGNAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPHVERLCMVCDMMVTAKGEIHAYQFYPAVMLSHARLT
YTEVAAVLANTRGPEALKHQERVGNLLNLYEVYRALLAARQARGAVDFETTETQIVCDDNGRIEKIVPRVRTEAHRLIEE
AMLAANVCSADFIGHAGRAGLYRVHEGPTPEKQEILRAYLKAMGVGMSIGDDPRPAEFQAIAEATKDRVDAQQIHTMLLR
SMQQAIYTPVNSGHFGLAFEAYTHFTSPIRRYPDLLVHRVIKSILSGTKYVLPALPTPGEAQFKLAKRLASKGGESSARP
SKTGGVISVRETQAWEAAGLHCSANERRADEASRDVEAWLKCQYMREHLGEEYSGVVSAVTSFGIFVTLDALYVEGLVHI
TELGGEYFKFDEARQELRGERTGIRYAIGARVRVQVSRVDLDGRKIDFRLVHEAGDGFSTKGPKSRDGAKRGSSAAALDG
RSASVPTARESREEGSRRRPHKQALAGKKAAGGKNPSKGRKSRG

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=483, Percent_Identity=31.8840579710145, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI190014623, Length=495, Percent_Identity=31.3131313131313, Blast_Score=190, Evalue=6e-48,
Organism=Homo sapiens, GI134288890, Length=411, Percent_Identity=30.4136253041363, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI19115966, Length=501, Percent_Identity=29.940119760479, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI219521928, Length=501, Percent_Identity=29.940119760479, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI87082383, Length=677, Percent_Identity=46.2333825701625, Blast_Score=597, Evalue=1e-171,
Organism=Escherichia coli, GI1787542, Length=530, Percent_Identity=29.0566037735849, Blast_Score=161, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI212645896, Length=410, Percent_Identity=31.219512195122, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17553506, Length=424, Percent_Identity=29.4811320754717, Blast_Score=144, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324552, Length=516, Percent_Identity=26.937984496124, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24649634, Length=480, Percent_Identity=29.5833333333333, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24654592, Length=448, Percent_Identity=30.1339285714286, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI19922976, Length=448, Percent_Identity=30.1339285714286, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24654597, Length=448, Percent_Identity=30.1339285714286, Blast_Score=139, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 84251; Mature: 84251

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIKKNHSESSVAKVSLDEIEGTVQGHRDGHGFVLRDDGQPDIYLPANEMRAVLHKDRVR
CCCCCCCCCCHHHEEEHHHHHHHHCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHE
VRIARQDRRGRPEGRVVEILERPPQPIIGRLLQESGVWLVAPEDKRYGQDVLIPKGATGA
EEEEHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCC
AATGQVVVVELTEPPALFGQPVGRVVEVLGEVDDPGMEVEIAVRKYGVPHEFSEACLDQA
CCCCCEEEEEECCCCHHHCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
KALPDKVRAQDKRRRVDLTDVPLVTIDGEDARDFDDAVYCEPAKIGRAKGWRLLVAIADV
HCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEECHHHCCCCCCCEEEEEEHHH
SHYVETGNAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPHVERLCMVCDMMVTAK
HHHHHCCCEEEECCCCCCHHCCCCHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
GEIHAYQFYPAVMLSHARLTYTEVAAVLANTRGPEALKHQERVGNLLNLYEVYRALLAAR
CCEEEEEEHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARGAVDFETTETQIVCDDNGRIEKIVPRVRTEAHRLIEEAMLAANVCSADFIGHAGRAG
HHCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LYRVHEGPTPEKQEILRAYLKAMGVGMSIGDDPRPAEFQAIAEATKDRVDAQQIHTMLLR
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
SMQQAIYTPVNSGHFGLAFEAYTHFTSPIRRYPDLLVHRVIKSILSGTKYVLPALPTPGE
HHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCH
AQFKLAKRLASKGGESSARPSKTGGVISVRETQAWEAAGLHCSANERRADEASRDVEAWL
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHHH
KCQYMREHLGEEYSGVVSAVTSFGIFVTLDALYVEGLVHITELGGEYFKFDEARQELRGE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
RTGIRYAIGARVRVQVSRVDLDGRKIDFRLVHEAGDGFSTKGPKSRDGAKRGSSAAALDG
CCCEEEEECCEEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCHHCCCCCEEECC
RSASVPTARESREEGSRRRPHKQALAGKKAAGGKNPSKGRKSRG
CCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYIKKNHSESSVAKVSLDEIEGTVQGHRDGHGFVLRDDGQPDIYLPANEMRAVLHKDRVR
CCCCCCCCCCHHHEEEHHHHHHHHCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHE
VRIARQDRRGRPEGRVVEILERPPQPIIGRLLQESGVWLVAPEDKRYGQDVLIPKGATGA
EEEEHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCC
AATGQVVVVELTEPPALFGQPVGRVVEVLGEVDDPGMEVEIAVRKYGVPHEFSEACLDQA
CCCCCEEEEEECCCCHHHCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
KALPDKVRAQDKRRRVDLTDVPLVTIDGEDARDFDDAVYCEPAKIGRAKGWRLLVAIADV
HCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEECHHHCCCCCCCEEEEEEHHH
SHYVETGNAIDIDAYDRATSVYFPRRVIPMLPEKLSNGLCSLNPHVERLCMVCDMMVTAK
HHHHHCCCEEEECCCCCCHHCCCCHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
GEIHAYQFYPAVMLSHARLTYTEVAAVLANTRGPEALKHQERVGNLLNLYEVYRALLAAR
CCEEEEEEHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARGAVDFETTETQIVCDDNGRIEKIVPRVRTEAHRLIEEAMLAANVCSADFIGHAGRAG
HHCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LYRVHEGPTPEKQEILRAYLKAMGVGMSIGDDPRPAEFQAIAEATKDRVDAQQIHTMLLR
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
SMQQAIYTPVNSGHFGLAFEAYTHFTSPIRRYPDLLVHRVIKSILSGTKYVLPALPTPGE
HHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCH
AQFKLAKRLASKGGESSARPSKTGGVISVRETQAWEAAGLHCSANERRADEASRDVEAWL
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHHH
KCQYMREHLGEEYSGVVSAVTSFGIFVTLDALYVEGLVHITELGGEYFKFDEARQELRGE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
RTGIRYAIGARVRVQVSRVDLDGRKIDFRLVHEAGDGFSTKGPKSRDGAKRGSSAAALDG
CCCEEEEECCEEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCHHCCCCCEEECC
RSASVPTARESREEGSRRRPHKQALAGKKAAGGKNPSKGRKSRG
CCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]