BacMap

Definition	Acidovorax ebreus TPSY chromosome, complete genome.
Accession	NC_011992
Length	3,796,573

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The map label for this gene is budC [H]

Identifier: 222110444

GI number: 222110444

Start: 1304092

End: 1304880

Strand: Direct

Name: budC [H]

Synonym: Dtpsy_1241

Alternate gene names: 222110444

Gene position: 1304092-1304880 (Clockwise)

Preceding gene: 222110443

Following gene: 222110445

Centisome position: 34.35

GC content: 61.22

Gene sequence:

>789_bases
ATGGGTATGAAGGACAGGAGACAAGCGTCGCATATGGTTAAAGCATCGAAGGTGGCCATCGTTACTGGGGCTGGGTCAGG
GATTGGCAAGGCGGCGGCTTTGGCGCTGCTGCGCGATGGATGGAGCGTTGTTCTCGCTGGGCGGCGTGAGTCGCTATTGC
AGGAGGTCGTGGGCGAATCAGAGGGTGGGGTGCGTGCGCTCGCCGTTCCCACCGATGTGTCCGACCCCGCTGCGGTGCGC
ACGCTGTTTGACCGGGCTGTGCTTCAGTTCGGGCGCGTGGATCTGTTGTTTAACAATGCGGGCGTGAGTGCTCCCGCCGT
GCCGCTGGAGGATCTGGCGGTGGAGCAGTGGCGGCAGGTGGTCGACGTCAACCTCAATGGCATGTTCTTTTGCATGCAGA
ACGCTTTTCGGGTCATGAAGACGCAGTCGCCACGGGGCGGGCGCATCATCAATAACGGCTCGATTTCAGCGCACGCCCCG
CGGCCCAACTCCATCGCCTACACCGCCACCAAGCATGCGGTGATGGGCCTGACAAAGACAGCGGCTCTCGATGGGCGCAA
GTACGATATTGCGGTGGGACAAATCGATGTCGGGAACGCCCAGACCGAGCTGGCCCAGCGCATGACGCAGGGCGTGCAAC
AGGCCAATGGCCAGATTGCGGCGGAACCTCTGATGGACGTGGACATCGTGGGGCAGTCCGTGCTTTACATGGCCAATCTT
CCGCTGGAGGCTAATGTGTTGTTCCATACCGTCATGGCGACCAAAATGCCTTTTGTCGGGCGTGGCTGA

Upstream 100 bases:

>100_bases
GGAGCCGGCGGCGCCCGCACAAGCAGGCCTTGGCCGGCAAAAAAGCGGCAGGTGGCAAGAACCCCTCTAAGGGCCGCAAA
TCCCGCGGTTGAGTAGATTG

Downstream 100 bases:

>100_bases
GAAATTCTTACGCCCCTTGCTGCACGCGGCAGGGGCGCTGTGCATGCTGCTCGCTGCCTCGGTGGCCGCCGCGCCGGCCG
TGGATATGGCGCCGCGTGTG

Product: short-chain dehydrogenase/reductase sdr

Products: NA

Alternate protein names: Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MGMKDRRQASHMVKASKVAIVTGAGSGIGKAAALALLRDGWSVVLAGRRESLLQEVVGESEGGVRALAVPTDVSDPAAVR
TLFDRAVLQFGRVDLLFNNAGVSAPAVPLEDLAVEQWRQVVDVNLNGMFFCMQNAFRVMKTQSPRGGRIINNGSISAHAP
RPNSIAYTATKHAVMGLTKTAALDGRKYDIAVGQIDVGNAQTELAQRMTQGVQQANGQIAAEPLMDVDIVGQSVLYMANL
PLEANVLFHTVMATKMPFVGRG

Sequences:

>Translated_262_residues
MGMKDRRQASHMVKASKVAIVTGAGSGIGKAAALALLRDGWSVVLAGRRESLLQEVVGESEGGVRALAVPTDVSDPAAVR
TLFDRAVLQFGRVDLLFNNAGVSAPAVPLEDLAVEQWRQVVDVNLNGMFFCMQNAFRVMKTQSPRGGRIINNGSISAHAP
RPNSIAYTATKHAVMGLTKTAALDGRKYDIAVGQIDVGNAQTELAQRMTQGVQQANGQIAAEPLMDVDIVGQSVLYMANL
PLEANVLFHTVMATKMPFVGRG
>Mature_261_residues
GMKDRRQASHMVKASKVAIVTGAGSGIGKAAALALLRDGWSVVLAGRRESLLQEVVGESEGGVRALAVPTDVSDPAAVRT
LFDRAVLQFGRVDLLFNNAGVSAPAVPLEDLAVEQWRQVVDVNLNGMFFCMQNAFRVMKTQSPRGGRIINNGSISAHAPR
PNSIAYTATKHAVMGLTKTAALDGRKYDIAVGQIDVGNAQTELAQRMTQGVQQANGQIAAEPLMDVDIVGQSVLYMANLP
LEANVLFHTVMATKMPFVGRG

Specific function: Catalyzes the reversible reduction of (S)-acetoin to 2,3-butanediol in the presence of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=28.755364806867, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI31542939, Length=171, Percent_Identity=34.5029239766082, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=34.1176470588235, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI15277342, Length=206, Percent_Identity=32.0388349514563, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI59889578, Length=178, Percent_Identity=30.3370786516854, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI32483357, Length=195, Percent_Identity=28.7179487179487, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI10190704, Length=238, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI7706318, Length=205, Percent_Identity=31.219512195122, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=31.1224489795918, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=196, Percent_Identity=31.1224489795918, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19923817, Length=174, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4504505, Length=245, Percent_Identity=31.4285714285714, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI40548397, Length=191, Percent_Identity=29.8429319371728, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI214010158, Length=191, Percent_Identity=29.8429319371728, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI214010156, Length=191, Percent_Identity=29.8429319371728, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI22758144, Length=191, Percent_Identity=29.8429319371728, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI209862901, Length=219, Percent_Identity=27.8538812785388, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI19923983, Length=219, Percent_Identity=27.8538812785388, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4503817, Length=179, Percent_Identity=28.4916201117318, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI83715985, Length=179, Percent_Identity=31.8435754189944, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1788459, Length=213, Percent_Identity=35.6807511737089, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789208, Length=208, Percent_Identity=32.6923076923077, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=30.1204819277108, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082100, Length=198, Percent_Identity=32.3232323232323, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082160, Length=193, Percent_Identity=32.1243523316062, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787335, Length=193, Percent_Identity=28.4974093264249, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787820, Length=245, Percent_Identity=24.8979591836735, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790717, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=192, Percent_Identity=28.125, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789057, Length=189, Percent_Identity=31.2169312169312, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786812, Length=165, Percent_Identity=33.9393939393939, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787905, Length=204, Percent_Identity=30.8823529411765, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=172, Percent_Identity=35.4651162790698, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=218, Percent_Identity=29.3577981651376, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=173, Percent_Identity=32.9479768786127, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=206, Percent_Identity=32.0388349514563, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=227, Percent_Identity=30.3964757709251, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=206, Percent_Identity=31.5533980582524, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=216, Percent_Identity=30.0925925925926, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=196, Percent_Identity=30.1020408163265, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=205, Percent_Identity=29.7560975609756, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=224, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=243, Percent_Identity=32.5102880658436, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=207, Percent_Identity=29.4685990338164, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=204, Percent_Identity=28.921568627451, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=179, Percent_Identity=31.8435754189944, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997099, Length=272, Percent_Identity=28.6764705882353, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=225, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=198, Percent_Identity=28.2828282828283, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=201, Percent_Identity=30.3482587064677, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=207, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=176, Percent_Identity=28.9772727272727, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=215, Percent_Identity=29.7674418604651, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=208, Percent_Identity=33.1730769230769, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322067, Length=197, Percent_Identity=30.4568527918782, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=25.9414225941423, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007236, Length=254, Percent_Identity=31.1023622047244, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=34.4086021505376, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859837, Length=206, Percent_Identity=35.9223300970874, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=236, Percent_Identity=30.0847457627119, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639444, Length=203, Percent_Identity=33.4975369458128, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=30.4123711340206, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364494, Length=173, Percent_Identity=32.9479768786127, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641232, Length=175, Percent_Identity=34.2857142857143, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=29.8969072164948, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24580925, Length=183, Percent_Identity=30.0546448087432, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24663911, Length=246, Percent_Identity=28.4552845528455, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24644339, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355319, Length=211, Percent_Identity=25.1184834123223, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648944, Length=232, Percent_Identity=28.0172413793103, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007234, Length=255, Percent_Identity=30.9803921568627, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737361, Length=212, Percent_Identity=31.1320754716981, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641388, Length=248, Percent_Identity=28.2258064516129, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=170, Percent_Identity=34.7058823529412, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571387, Length=240, Percent_Identity=27.9166666666667, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24648693, Length=170, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355889, Length=170, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007232, Length=188, Percent_Identity=33.5106382978723, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358495, Length=213, Percent_Identity=26.7605633802817, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584748, Length=181, Percent_Identity=31.4917127071823, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076933, Length=181, Percent_Identity=31.4917127071823, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014007
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.304 [H]

Molecular weight: Translated: 27868; Mature: 27736

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMKDRRQASHMVKASKVAIVTGAGSGIGKAAALALLRDGWSVVLAGRRESLLQEVVGES
CCCCHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCC
EGGVRALAVPTDVSDPAAVRTLFDRAVLQFGRVDLLFNNAGVSAPAVPLEDLAVEQWRQV
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
VDVNLNGMFFCMQNAFRVMKTQSPRGGRIINNGSISAHAPRPNSIAYTATKHAVMGLTKT
HCCCCCEEEEEHHHHHHHHHCCCCCCCEEEECCCEEECCCCCCCEEEEEHHHHHHHHHHH
AALDGRKYDIAVGQIDVGNAQTELAQRMTQGVQQANGQIAAEPLMDVDIVGQSVLYMANL
HHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCEEEEECC
PLEANVLFHTVMATKMPFVGRG
CCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GMKDRRQASHMVKASKVAIVTGAGSGIGKAAALALLRDGWSVVLAGRRESLLQEVVGES
CCCHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCC
EGGVRALAVPTDVSDPAAVRTLFDRAVLQFGRVDLLFNNAGVSAPAVPLEDLAVEQWRQV
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
VDVNLNGMFFCMQNAFRVMKTQSPRGGRIINNGSISAHAPRPNSIAYTATKHAVMGLTKT
HCCCCCEEEEEHHHHHHHHHCCCCCCCEEEECCCEEECCCCCCCEEEEEHHHHHHHHHHH
AALDGRKYDIAVGQIDVGNAQTELAQRMTQGVQQANGQIAAEPLMDVDIVGQSVLYMANL
HHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCEEEEECC
PLEANVLFHTVMATKMPFVGRG
CCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11173520 [H]