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The map label for this gene is fabZ [H]

Identifier: 222110437

GI number: 222110437

Start: 1297031

End: 1297471

Strand: Direct

Name: fabZ [H]

Synonym: Dtpsy_1234

Alternate gene names: 222110437

Gene position: 1297031-1297471 (Clockwise)

Preceding gene: 222110436

Following gene: 222110438

Centisome position: 34.16

GC content: 61.68

Gene sequence:

>441_bases
ATGATGGATATCCACCAAATTCTCAAACTCCTGCCCCACCGCTATCCGTTCCTGCTGGTGGATCGGGTGAATGAGCTCGA
ACGCGGCAAGCGCATCCTGGCCATCAAGAACGTGACCATTAACGAGCCGTTTTTCACGGGGCACTTCCCCGCACGCCCGG
TGATGCCCGGGGTGTTGATTCTCGAAGCACTCGCGCAGGCGGCGGGCTTGCTGTCGTTCGACATGATGGGTGAGGCGCCG
GGCGACGACAAGGTCTTTTACTTCGTCGGTATCGATGGTGCGCGCTTCAAGCGCCCCGTGGAGCCAGGCGATCAGCTCAT
CCTCGACGTGGAACTGGACCGCATCAAGGGCGGCATCTACAAGTTCAAGGGCGTCGCGCGCGTGGGCGACAGCGTCGCGT
GCGAGGCCGAGATCATGTGCACCATGCGCACGGTGGCCTGA

Upstream 100 bases:

>100_bases
GGAAAAGAACGCGGCCACGCTGCGGCAGCTGTACCGGCTGCGTGAACGCATCAAGGCTCTCGAACAAACACGAAAAGACG
GCTAGGCCGCTCACAGAAAA

Downstream 100 bases:

>100_bases
CGGGCCGAGGATTTCGCTTGGCGCCCAACATCCATTCCACGGCCCTCGTTGATGCGGCCGCGCAGTTGGACCCTACTGTT
ACGGTGGGGCCGTATGCGGT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MMDIHQILKLLPHRYPFLLVDRVNELERGKRILAIKNVTINEPFFTGHFPARPVMPGVLILEALAQAAGLLSFDMMGEAP
GDDKVFYFVGIDGARFKRPVEPGDQLILDVELDRIKGGIYKFKGVARVGDSVACEAEIMCTMRTVA

Sequences:

>Translated_146_residues
MMDIHQILKLLPHRYPFLLVDRVNELERGKRILAIKNVTINEPFFTGHFPARPVMPGVLILEALAQAAGLLSFDMMGEAP
GDDKVFYFVGIDGARFKRPVEPGDQLILDVELDRIKGGIYKFKGVARVGDSVACEAEIMCTMRTVA
>Mature_146_residues
MMDIHQILKLLPHRYPFLLVDRVNELERGKRILAIKNVTINEPFFTGHFPARPVMPGVLILEALAQAAGLLSFDMMGEAP
GDDKVFYFVGIDGARFKRPVEPGDQLILDVELDRIKGGIYKFKGVARVGDSVACEAEIMCTMRTVA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=57.1428571428571, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16273; Mature: 16273

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDIHQILKLLPHRYPFLLVDRVNELERGKRILAIKNVTINEPFFTGHFPARPVMPGVLI
CCCHHHHHHHCCCCCCEEEEHHHHHHHCCCEEEEEECEEECCCEEECCCCCCCCCCHHHH
LEALAQAAGLLSFDMMGEAPGDDKVFYFVGIDGARFKRPVEPGDQLILDVELDRIKGGIY
HHHHHHHHCCEEEECCCCCCCCCEEEEEEECCCHHCCCCCCCCCEEEEEEEHHHHCCCHH
KFKGVARVGDSVACEAEIMCTMRTVA
EECCHHHCCCCCEECCEEEEEEEECC
>Mature Secondary Structure
MMDIHQILKLLPHRYPFLLVDRVNELERGKRILAIKNVTINEPFFTGHFPARPVMPGVLI
CCCHHHHHHHCCCCCCEEEEHHHHHHHCCCEEEEEECEEECCCEEECCCCCCCCCCHHHH
LEALAQAAGLLSFDMMGEAPGDDKVFYFVGIDGARFKRPVEPGDQLILDVELDRIKGGIY
HHHHHHHHCCEEEECCCCCCCCCEEEEEEECCCHHCCCCCCCCCEEEEEEEHHHHCCCHH
KFKGVARVGDSVACEAEIMCTMRTVA
EECCHHHCCCCCEECCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA