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The map label for this gene is cdsA [H]

Identifier: 222110431

GI number: 222110431

Start: 1289640

End: 1290494

Strand: Direct

Name: cdsA [H]

Synonym: Dtpsy_1228

Alternate gene names: 222110431

Gene position: 1289640-1290494 (Clockwise)

Preceding gene: 222110430

Following gene: 222110432

Centisome position: 33.97

GC content: 68.89

Gene sequence:

>855_bases
ATGCTCAAGCAACGTGTCATCACCGCGTTGGTCCTGCTGGCCATTCTGTTGCCGGCATTGTTCTATCCCTCGTTCGTGCC
CTTTGCCGTGGTGACGCTGGTCATGATGGCTGCGGCGGCGTGGGAATGGGGTCGGCTCAACGGCCTCGGCGGTGGCGGCA
GCATCGGCCTGGGGGCGGCGTGTGTAGTGCTGTGCGGCCTCGGGTGGGCCGCGGGCTGGCTGCACCAGCCGCTGCCCTGG
CTGTGGCTGGTGGGCGGCGCTGCCTGGGTGCTGGGTGGGGCCGCCTTGCTGCGCGTGGGCGTGGCCGGCTGGCCGCAGCT
GCCGCGCGGGCTGCGCGTGGCCGGCGGCGTGCTGGCGCTGTGGATGGCCTGGCTGGCCGTGGCCCAGGCGCGCGTGGTGG
GGGTCAATTTCCTTCTGTCGGTTCTGACCCTGGTGTGGGCGGCCGATATCTTTGCCTACTTTGCCGGCCGCGCTTTTGGC
CTGCGCTTCACGCGCAACAAGCTGGCTCCCTCTATCAGCCCCGGCAAGAGCTGGGAAGGGGTGTGGGGTGGCATGCTGGG
TGTGCTGGTGCTGGCCGCGGCCTGGACCGCGGCCGATGGGGCCTGGCAGGCCAGCGTGCCCAGCCTGTACTCACGCCTGG
CAGCCCAGGGCGTATGGCTGCTAGTCGTTGGCGCATTGTTCATGGCCGCCATGAGCGTGGTAGGCGACCTGGTGGAGTCG
CTCATCAAGCGCAGCGCCGGTGTCAAGGACAGCAGCGGCCTGCTGCCTGGCCACGGCGGCGTACTGGACCGCATTGATGC
GCTGCTGCCCACGCTGCCCTTGGCCATGATGCTTTCTCATTTCGCATCCGCATGA

Upstream 100 bases:

>100_bases
CGAGCGCCGCTTTGGCCAAACCTCCGACCAGGTACAAGCGCAGCAGCCCGGTTCGCTGCGTGCCTGATTCCGTCCACCGC
ACATCGCTGAAGGGGTCTGG

Downstream 100 bases:

>100_bases
AACAACGTCTCACGGTGCTGGGTTCTACGGGATCCATCGGCACCAGCACCCTCGACGTGGTGGCACGCCACCCCGATCGC
TACGAAGTCTTTGCGCTGAG

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MLKQRVITALVLLAILLPALFYPSFVPFAVVTLVMMAAAAWEWGRLNGLGGGGSIGLGAACVVLCGLGWAAGWLHQPLPW
LWLVGGAAWVLGGAALLRVGVAGWPQLPRGLRVAGGVLALWMAWLAVAQARVVGVNFLLSVLTLVWAADIFAYFAGRAFG
LRFTRNKLAPSISPGKSWEGVWGGMLGVLVLAAAWTAADGAWQASVPSLYSRLAAQGVWLLVVGALFMAAMSVVGDLVES
LIKRSAGVKDSSGLLPGHGGVLDRIDALLPTLPLAMMLSHFASA

Sequences:

>Translated_284_residues
MLKQRVITALVLLAILLPALFYPSFVPFAVVTLVMMAAAAWEWGRLNGLGGGGSIGLGAACVVLCGLGWAAGWLHQPLPW
LWLVGGAAWVLGGAALLRVGVAGWPQLPRGLRVAGGVLALWMAWLAVAQARVVGVNFLLSVLTLVWAADIFAYFAGRAFG
LRFTRNKLAPSISPGKSWEGVWGGMLGVLVLAAAWTAADGAWQASVPSLYSRLAAQGVWLLVVGALFMAAMSVVGDLVES
LIKRSAGVKDSSGLLPGHGGVLDRIDALLPTLPLAMMLSHFASA
>Mature_284_residues
MLKQRVITALVLLAILLPALFYPSFVPFAVVTLVMMAAAAWEWGRLNGLGGGGSIGLGAACVVLCGLGWAAGWLHQPLPW
LWLVGGAAWVLGGAALLRVGVAGWPQLPRGLRVAGGVLALWMAWLAVAQARVVGVNFLLSVLTLVWAADIFAYFAGRAFG
LRFTRNKLAPSISPGKSWEGVWGGMLGVLVLAAAWTAADGAWQASVPSLYSRLAAQGVWLLVVGALFMAAMSVVGDLVES
LIKRSAGVKDSSGLLPGHGGVLDRIDALLPTLPLAMMLSHFASA

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=293, Percent_Identity=37.2013651877133, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787677, Length=137, Percent_Identity=35.036496350365, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29614; Mature: 29614

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQRVITALVLLAILLPALFYPSFVPFAVVTLVMMAAAAWEWGRLNGLGGGGSIGLGAA
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
CVVLCGLGWAAGWLHQPLPWLWLVGGAAWVLGGAALLRVGVAGWPQLPRGLRVAGGVLAL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
WMAWLAVAQARVVGVNFLLSVLTLVWAADIFAYFAGRAFGLRFTRNKLAPSISPGKSWEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
VWGGMLGVLVLAAAWTAADGAWQASVPSLYSRLAAQGVWLLVVGALFMAAMSVVGDLVES
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIKRSAGVKDSSGLLPGHGGVLDRIDALLPTLPLAMMLSHFASA
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8654980; 10984043 [H]