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The map label for this gene is clpX [H]

Identifier: 222110342

GI number: 222110342

Start: 1185892

End: 1187157

Strand: Direct

Name: clpX [H]

Synonym: Dtpsy_1129

Alternate gene names: 222110342

Gene position: 1185892-1187157 (Clockwise)

Preceding gene: 222110341

Following gene: 222110343

Centisome position: 31.24

GC content: 56.24

Gene sequence:

>1266_bases
ATGGCCGAGAAAAAAGGCTCCTCCAGCGAAAAAACCCTTTACTGCTCTTTCTGCGGTAAAAGCCAGCACGAAGTAAAGAA
GCTGATCGCCGGTCCGTCGGTCTTTATCTGCGACGAGTGCATTGACCTGTGCAACGAGATCATCCGTGATGAGCTGCCCA
CCGGCGATGCCGGACGCGAAGGCCGCGGAGATCTGCCTACGCCTGCGGAAATCAAGACCAACCTTGATCATTACGTGATT
GGCCAGGAAAAGGCCAAACGTACGCTGGCCGTCGCCGTGTACAACCATTACAAGCGTCTGCGCCACAAGGACAAGGCCGG
TAAGGACGAGGTGGAACTGTCCAAGAGCAACATCCTGTTGATCGGCCCTACGGGGTCGGGCAAGACGTTGCTTGCGCAGA
CCTTGGCGCGGCAGCTCGATGTGCCTTTCGTGATGGCTGACGCCACCACGCTGACGGAAGCCGGCTATGTTGGAGAGGAC
GTGGAGAACATCGTCCAGAAACTCCTGCAAAGCTGCAACTACGATGTGGAACGTGCCCAGCGGGGCATTGTCTACATCGA
CGAAATCGACAAAATTTCGCGCAAATCCGACAACCCCAGTATTACGCGGGATGTCTCAGGTGAAGGTGTGCAGCAAGCGC
TGCTCAAGCTCATCGAGGGGACCATGGCGAGCGTGCCTCCACAAGGTGGACGCAAGCATCCCAATCAGGATTTTCTGCAG
ATCGATACCACCAACATTCTGTTCATTTGTGGTGGTGCGTTTGCTGGGCTGGAAAAGGTCATTGAGAACCGTACTGAAGC
TTCCGGTATTGGCTTTGGCGCGGCAGTGCGTAGCAAAAAGCAGCGTTCTTTGACCGAGGTGTTTCAGGATATCGAGCCTG
AGGATCTCATCAAATTCGGCCTGATTCCAGAGTTGGTGGGTCGCATGCCCGTGGTCACAGCGCTGGCCGAACTGAGCGAG
GACGCGCTGGTGCAAATTCTCACCGAGCCCAAAAACGCCTTGGTCAAGCAGTACAGCAAGTTGCTGGCGATGGAAGGCGT
TGAGCTGGAAATTCGTCCCGCTGCGTTGAAGTCCATCGCGCGAAAAGCCATCGCACGCAAGACGGGTGCCCGCGGCTTGC
GCTCCATTCTTGAGCAAGCGTTGATTGGCACCATGTTTGACTTGCCCAACGTCTCCAACGTGGAAAAGGTGGTGGTGGAC
GAGGCCACCATCGAAGAGAACAAGGCCCCTTTGCTGGTTTATCGCGAGGCCGCCAAGACCGCCTGA

Upstream 100 bases:

>100_bases
TGAGTTTGGGCCGGCGCGCGCGGCGTTTCCCCCTGTGGGAAACGCCGTTTTTATTTCGTTATCATCTTGACAACATCCCC
AGTCATAAGGCATTGCCCCC

Downstream 100 bases:

>100_bases
AAGCCGTGAGCCGCCGGGAGCAGAGCGCGTGATTGATGCGCCCGGCGGGCCATGTCGCTAACACCTGGGTGCAGATGCTG
CCGGGTTGAAAAATGTGGTC

Product: ATP-dependent protease ATP-binding subunit clpx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MAEKKGSSSEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPTGDAGREGRGDLPTPAEIKTNLDHYVI
GQEKAKRTLAVAVYNHYKRLRHKDKAGKDEVELSKSNILLIGPTGSGKTLLAQTLARQLDVPFVMADATTLTEAGYVGED
VENIVQKLLQSCNYDVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
IDTTNILFICGGAFAGLEKVIENRTEASGIGFGAAVRSKKQRSLTEVFQDIEPEDLIKFGLIPELVGRMPVVTALAELSE
DALVQILTEPKNALVKQYSKLLAMEGVELEIRPAALKSIARKAIARKTGARGLRSILEQALIGTMFDLPNVSNVEKVVVD
EATIEENKAPLLVYREAAKTA

Sequences:

>Translated_421_residues
MAEKKGSSSEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPTGDAGREGRGDLPTPAEIKTNLDHYVI
GQEKAKRTLAVAVYNHYKRLRHKDKAGKDEVELSKSNILLIGPTGSGKTLLAQTLARQLDVPFVMADATTLTEAGYVGED
VENIVQKLLQSCNYDVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
IDTTNILFICGGAFAGLEKVIENRTEASGIGFGAAVRSKKQRSLTEVFQDIEPEDLIKFGLIPELVGRMPVVTALAELSE
DALVQILTEPKNALVKQYSKLLAMEGVELEIRPAALKSIARKAIARKTGARGLRSILEQALIGTMFDLPNVSNVEKVVVD
EATIEENKAPLLVYREAAKTA
>Mature_420_residues
AEKKGSSSEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPTGDAGREGRGDLPTPAEIKTNLDHYVIG
QEKAKRTLAVAVYNHYKRLRHKDKAGKDEVELSKSNILLIGPTGSGKTLLAQTLARQLDVPFVMADATTLTEAGYVGEDV
ENIVQKLLQSCNYDVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQI
DTTNILFICGGAFAGLEKVIENRTEASGIGFGAAVRSKKQRSLTEVFQDIEPEDLIKFGLIPELVGRMPVVTALAELSED
ALVQILTEPKNALVKQYSKLLAMEGVELEIRPAALKSIARKAIARKTGARGLRSILEQALIGTMFDLPNVSNVEKVVVDE
ATIEENKAPLLVYREAAKTA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=329, Percent_Identity=50.7598784194529, Blast_Score=311, Evalue=9e-85,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=72.1153846153846, Blast_Score=611, Evalue=1e-176,
Organism=Escherichia coli, GI1790366, Length=102, Percent_Identity=43.1372549019608, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=307, Percent_Identity=47.2312703583062, Blast_Score=267, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=307, Percent_Identity=47.2312703583062, Blast_Score=267, Evalue=9e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=423, Percent_Identity=39.0070921985816, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=264, Percent_Identity=41.2878787878788, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6319704, Length=437, Percent_Identity=38.6727688787185, Blast_Score=279, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=46.5408805031447, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=46.5408805031447, Blast_Score=283, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45972; Mature: 45841

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKGSSSEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPTGDAGRE
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCC
GRGDLPTPAEIKTNLDHYVIGQEKAKRTLAVAVYNHYKRLRHKDKAGKDEVELSKSNILL
CCCCCCCCHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECCCCEEE
IGPTGSGKTLLAQTLARQLDVPFVMADATTLTEAGYVGEDVENIVQKLLQSCNYDVERAQ
EECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCCEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
IDTTNILFICGGAFAGLEKVIENRTEASGIGFGAAVRSKKQRSLTEVFQDIEPEDLIKFG
EECCEEEEEECCHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
LIPELVGRMPVVTALAELSEDALVQILTEPKNALVKQYSKLLAMEGVELEIRPAALKSIA
CHHHHHCCCHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
RKAIARKTGARGLRSILEQALIGTMFDLPNVSNVEKVVVDEATIEENKAPLLVYREAAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
A
C
>Mature Secondary Structure 
AEKKGSSSEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPTGDAGRE
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCC
GRGDLPTPAEIKTNLDHYVIGQEKAKRTLAVAVYNHYKRLRHKDKAGKDEVELSKSNILL
CCCCCCCCHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECCCCEEE
IGPTGSGKTLLAQTLARQLDVPFVMADATTLTEAGYVGEDVENIVQKLLQSCNYDVERAQ
EECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCCEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
IDTTNILFICGGAFAGLEKVIENRTEASGIGFGAAVRSKKQRSLTEVFQDIEPEDLIKFG
EECCEEEEEECCHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
LIPELVGRMPVVTALAELSEDALVQILTEPKNALVKQYSKLLAMEGVELEIRPAALKSIA
CHHHHHCCCHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
RKAIARKTGARGLRSILEQALIGTMFDLPNVSNVEKVVVDEATIEENKAPLLVYREAAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA